[Hub]/) : Traits : Heel T-Score :

chr17:19,142,226-21,023,006

Best TWAS P=2.46e-09 · Best GWAS P=6.46e-11 conditioned to 0.0074

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SPECC1 0.24 0.21 lasso 3 0.26 4.2e-31 -6.5 6.0 2.5e-09 -0.92 0.01 0.99 TRUE
2 GTEx Cells EBV-transformed lymphocytes SPECC1 0.12 0.13 lasso 2 0.11 1.6e-04 -5.8 5.8 4.8e-09 -1.00 0.03 0.91 FALSE
3 GTEx Pancreas RP11-78O7.2 0.10 0.00 enet 28 0.00 4.2e-01 -5.9 -5.5 2.8e-08 0.64 0.04 0.72 FALSE
4 GTEx Testis USP32P3 0.11 0.19 lasso 3 0.16 8.6e-08 -5.4 -5.6 1.7e-08 0.97 0.03 0.97 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma CYTSB 0.03 0.03 lasso 4 0.02 2.8e-05 -5.8 5.8 7.9e-09 -0.99 0.04 0.96 FALSE