[Hub]/) : Traits : Heel T-Score : ← →

chr18:12,520,514-14,816,209

Best TWAS P=2.01e-71 · Best GWAS P=8.21e-162 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum ZNF519 0.29 0.21 lasso 9 0.23 3.5e-12 -4.9 -7.6 3.5e-14 0.25 1.00 0.00 TRUE
2 GTEx Brain Cerebellar Hemisphere ZNF519 0.30 0.06 lasso 4 0.05 2.5e-02 -3.8 -10.7 1.1e-26 0.34 0.07 0.08 FALSE
3 GTEx Breast Mammary Tissue (Female) ZNF519 0.54 0.18 lasso 10 0.24 9.2e-08 -2.9 -10.1 6.3e-24 0.42 0.33 0.52 TRUE
4 GTEx Cells Transformed fibroblasts FAM210A 0.21 0.00 enet 34 0.09 4.3e-07 2.1 6.2 4.6e-10 -0.18 0.25 0.03 FALSE
5 GTEx Colon Sigmoid LDLRAD4 0.26 0.00 lasso 7 0.02 8.6e-02 4.8 5.3 1.3e-07 -0.05 0.16 0.06 TRUE
6 GTEx Lung RP11-411B10.3 0.15 0.07 enet 16 0.10 2.7e-08 -4.9 -6.5 6.3e-11 0.25 0.99 0.00 FALSE
7 GTEx Nerve Tibial FAM210A 0.25 0.02 enet 35 0.08 2.6e-06 11.3 12.1 7.3e-34 -0.45 0.04 0.76 FALSE
8 GTEx Pituitary ZNF519 0.39 0.27 lasso 4 0.18 3.1e-05 -3.5 -6.5 9.7e-11 0.30 0.24 0.30 TRUE
9 GTEx Skin Not Sun Exposed Suprapubic RP11-411B10.3 0.08 0.03 enet 10 0.05 1.6e-03 -2.2 -6.6 3.2e-11 0.16 0.11 0.05 FALSE
10 METSIM Adipose RNMT 0.06 0.04 lasso 7 0.05 6.6e-08 6.1 5.9 3.7e-09 -0.25 0.98 0.01 TRUE
11 NTR Blood RNMT 0.03 0.02 lasso 5 0.02 4.7e-06 6.1 6.4 2.0e-10 -0.26 0.99 0.00 FALSE
12 YFS Blood RNMT 0.11 0.12 lasso 6 0.12 8.0e-38 6.1 6.7 2.4e-11 -0.27 1.00 0.00 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma RNMT 0.03 0.00 enet 8 0.02 2.0e-03 6.0 17.9 2.0e-71 -0.48 0.02 0.37 TRUE
14 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C18orf19 0.07 0.01 blup 57 0.03 2.3e-03 13.8 13.8 1.4e-43 -0.29 0.04 0.09 TRUE
15 The Cancer Genome Atlas Prostate Adenocarcinoma C18orf19 0.17 0.05 enet 10 0.05 7.4e-06 3.6 10.4 4.1e-25 -0.42 0.38 0.31 TRUE