Best TWAS P=2.18e-09 · Best GWAS P=1.98e-11 conditioned to 0.00311
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | RP11-21J18.1 | 0.30 | -0.01 | enet | 8 | -0.01 | 5.0e-01 | -6.7 | -6.0 | 2.2e-09 | 0.88 | 0.02 | 0.77 | TRUE |
| 2 | GTEx | Testis | ANKRD12 | 0.40 | 0.32 | enet | 35 | 0.37 | 1.6e-17 | -4.9 | -5.6 | 2.1e-08 | 0.89 | 0.00 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | PTPRM | 0.06 | 0.05 | lasso | 1 | 0.04 | 4.7e-05 | -5.8 | 5.8 | 6.1e-09 | -0.01 | 0.01 | 0.98 | TRUE |