Best TWAS P=1.46e-201 · Best GWAS P=7.13e-302 conditioned to 5.56e-110
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | GREM2 | 0.15 | 0.07 | bslmm | 717 | 0.10 | 1.5e-12 | -1.9 | 5.3 | 1.0e-07 | -0.03 | 0.99 | 0.0 | TRUE |
2 | GTEx | Cells Transformed fibroblasts | GREM2 | 0.29 | 0.13 | enet | 51 | 0.13 | 1.1e-09 | 37.1 | 30.3 | 1.5e-201 | 0.73 | 0.00 | 1.0 | TRUE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | FMN2 | 0.14 | 0.03 | lasso | 7 | 0.06 | 2.2e-06 | -11.7 | 9.8 | 1.7e-22 | 0.35 | 0.24 | 0.3 | FALSE |