Best TWAS P=3.9e-11 · Best GWAS P=2.62e-87 conditioned to 3.68e-83
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | TMX4 | 0.10 | 0.04 | enet | 27 | 0.06 | 7.0e-08 | 5.14 | 5.9 | 3.0e-09 | -0.14 | 0.99 | 0.00 | FALSE |
2 | GTEx | Brain Cerebellum | TMX4 | 0.52 | 0.08 | enet | 34 | 0.18 | 6.8e-06 | 5.38 | 6.6 | 3.9e-11 | -0.13 | 0.43 | 0.04 | TRUE |
3 | GTEx | Brain Cortex | TMX4 | 0.32 | 0.03 | enet | 22 | 0.11 | 5.3e-04 | 2.96 | 6.5 | 6.8e-11 | -0.16 | 0.13 | 0.10 | TRUE |
4 | GTEx | Brain Hippocampus | BMP2 | 0.39 | 0.00 | enet | 27 | 0.04 | 3.6e-02 | -0.47 | -5.5 | 3.8e-08 | -0.08 | 0.11 | 0.05 | TRUE |