Best TWAS P=2.34e-19 · Best GWAS P=1.72e-85 conditioned to 4.29e-72
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | MKKS | 0.13 | 0.00 | lasso | 5 | 0.00 | 0.94700 | 4.4 | -6.8 | 1.3e-11 | 0.12 | 0.09 | 0.06 | TRUE |
| 2 | YFS | Blood | JAG1 | 0.02 | 0.00 | bslmm | 580 | 0.00 | 0.27100 | 5.7 | -8.1 | 4.8e-16 | 0.11 | 0.21 | 0.01 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | JAG1 | 0.08 | 0.08 | lasso | 2 | 0.06 | 0.00042 | -9.0 | -9.0 | 2.3e-19 | -0.03 | 0.35 | 0.02 | TRUE |