[Hub]/) : Traits : Heel T-Score : ← →

chr19:58,218,846-59,095,126

Best TWAS P=1.3e-09 · Best GWAS P=1.44e-07 conditioned to 0.029

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Aorta	ZBTB45	0.12	0.04	lasso	7	0.08	5.2e-05	4.3	-5.3	1.2e-07	0.59	0.08	0.85	FALSE
2	GTEx	Brain Cerebellum	ZNF584	0.24	0.10	lasso	4	0.12	2.0e-04	-4.9	-6.0	1.9e-09	0.86	0.02	0.77	FALSE
3	GTEx	Brain Cortex	ZNF584	0.30	0.21	lasso	12	0.15	6.0e-05	5.0	-5.4	7.4e-08	0.42	0.05	0.87	FALSE
4	GTEx	Breast Mammary Tissue	RPL23AP79	0.16	0.12	lasso	3	0.13	3.6e-07	4.7	5.6	2.8e-08	-0.28	0.05	0.91	FALSE
5	GTEx	Breast Mammary Tissue (Female)	RPL23AP79	0.14	0.07	enet	6	0.12	1.4e-04	3.7	5.2	2.3e-07	-0.17	0.04	0.30	FALSE
6	GTEx	Cells Transformed fibroblasts	CTD-2619J13.14	0.07	0.01	lasso	2	0.03	4.6e-03	-4.9	-5.9	3.1e-09	0.86	0.04	0.79	FALSE
7	GTEx	Colon Sigmoid	AC016629.8	0.19	0.04	lasso	6	0.04	2.0e-02	4.7	-5.9	4.2e-09	0.65	0.02	0.65	FALSE
8	GTEx	Pancreas	RPL23AP79	0.13	0.04	enet	18	0.04	6.3e-03	4.8	5.2	2.6e-07	-0.30	0.05	0.83	FALSE
9	GTEx	Skin Not Sun Exposed Suprapubic	CTD-2619J13.14	0.14	0.03	lasso	3	0.02	1.9e-02	5.0	6.1	1.3e-09	-0.57	0.03	0.78	TRUE
10	The Cancer Genome Atlas	Breast Invasive Carcinoma	ZBTB45	0.02	0.01	enet	10	0.01	1.9e-03	4.7	5.5	3.2e-08	-0.43	0.01	0.42	FALSE
11	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MZF1	0.07	0.04	lasso	3	0.04	1.5e-05	4.7	-5.2	1.6e-07	0.50	0.00	0.94	FALSE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZNF584	0.09	0.06	enet	10	0.07	1.1e-08	-5.3	-5.5	4.1e-08	0.85	0.00	0.99	FALSE
13	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ZNF324B	0.10	0.08	blup	45	0.09	6.0e-05	4.7	5.2	2.4e-07	-0.46	0.05	0.86	FALSE
14	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ZNF584	0.19	0.13	lasso	7	0.13	4.9e-06	5.0	-5.4	6.0e-08	0.51	0.03	0.92	FALSE