[Hub]/) : Traits : Heel T-Score : ← →

chr22:45,199,058-47,338,438

Best TWAS P=1.39e-11 · Best GWAS P=3.22e-22 conditioned to 5.38e-11

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous LINC00899 0.17 0.04 lasso 5 0.06 1.1e-05 5.4 6.4 1.2e-10 0.50 0.22 0.72 FALSE
2 GTEx Cells Transformed fibroblasts FBLN1 0.09 0.04 lasso 9 0.06 2.4e-05 -5.9 6.2 5.4e-10 0.05 0.26 0.04 TRUE
3 GTEx Cells Transformed fibroblasts ATXN10 0.17 0.04 lasso 5 0.03 2.6e-03 5.1 6.0 2.0e-09 0.03 0.19 0.03 TRUE
4 GTEx Lung ATXN10 0.14 0.08 enet 20 0.08 5.2e-07 3.4 5.5 3.9e-08 0.07 0.57 0.03 FALSE
5 GTEx Muscle Skeletal LINC00899 0.24 0.09 lasso 9 0.07 8.3e-08 6.2 6.8 1.4e-11 0.52 0.91 0.09 TRUE
6 GTEx Nerve Tibial ATXN10 0.15 0.06 enet 57 0.04 8.6e-04 6.6 5.5 4.4e-08 0.10 0.14 0.32 FALSE
7 GTEx Nerve Tibial PPARA 0.14 0.04 enet 22 0.04 1.3e-03 4.2 -5.4 6.2e-08 -0.04 0.39 0.02 TRUE
8 The Cancer Genome Atlas Brain Lower Grade Glioma RIBC2 0.03 0.01 blup 59 0.03 1.8e-04 4.0 5.8 7.4e-09 0.05 0.14 0.73 FALSE
9 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ATXN10 0.04 0.02 blup 113 0.03 1.2e-04 4.1 5.8 5.9e-09 0.03 0.02 0.91 FALSE
10 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma RIBC2 0.11 0.02 blup 58 0.09 2.0e-04 4.7 5.7 1.0e-08 0.06 0.05 0.63 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma LOC100271722 0.05 0.04 enet 8 0.09 7.5e-09 4.4 5.4 6.6e-08 0.42 1.00 0.00 FALSE