[Hub]/) : Traits : Heel T-Score :

chr22:49,471,519-51,219,006

Best TWAS P=8.61e-15 · Best GWAS P=1.28e-17 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ALG12 0.04 0.03 lasso 2 0.02 7.6e-04 -5.2 -6.7 2.5e-11 0.12 0.03 0.96 FALSE
2 CommonMind Brain Pre-frontal Cortex CRELD2 0.03 0.01 lasso 5 0.02 2.9e-03 -5.5 -7.2 7.4e-13 0.11 0.05 0.82 FALSE
3 CommonMind Brain Pre-frontal Cortex MLC1 0.05 0.01 blup 412 0.02 8.2e-04 1.3 6.1 1.3e-09 -0.42 0.12 0.54 TRUE
4 CommonMind Brain Pre-frontal Cortex PPP6R2 0.14 0.02 blup 369 0.09 5.9e-11 -8.5 -6.6 5.4e-11 0.68 0.01 0.99 FALSE
5 CommonMind Brain Pre-frontal Cortex TUBGCP6 0.14 0.10 lasso 5 0.10 6.3e-12 -6.0 -6.2 5.5e-10 0.18 1.00 0.00 FALSE
6 GTEx Adipose Visceral Omentum PPP6R2 0.19 0.09 enet 7 0.03 7.8e-03 4.7 -5.6 1.8e-08 0.29 0.19 0.08 FALSE
7 GTEx Adipose Visceral Omentum ALG12 0.14 0.01 lasso 6 0.03 1.4e-02 -8.1 -7.8 8.6e-15 0.09 0.01 0.96 TRUE
8 GTEx Artery Aorta PPP6R2 0.14 0.14 lasso 3 0.16 2.8e-09 4.7 -5.3 1.0e-07 0.22 0.99 0.00 FALSE
9 GTEx Artery Tibial SELO 0.09 0.05 lasso 4 0.06 1.8e-05 -6.1 -6.0 1.7e-09 0.17 0.81 0.01 FALSE
10 GTEx Artery Tibial PPP6R2 0.14 0.07 lasso 4 0.08 5.6e-07 4.7 -5.6 1.7e-08 0.30 0.97 0.00 FALSE
11 GTEx Artery Tibial CRELD2 0.09 0.09 lasso 1 0.08 1.5e-06 -5.6 -5.6 2.3e-08 0.10 0.97 0.01 FALSE
12 GTEx Brain Cerebellar Hemisphere ZBED4 0.17 0.15 lasso 2 0.17 3.6e-05 -5.6 5.6 1.8e-08 -0.10 0.12 0.58 FALSE
13 GTEx Brain Cerebellum TUBGCP6 0.37 0.00 lasso 6 0.01 1.5e-01 -5.1 -7.7 1.8e-14 0.16 0.07 0.06 TRUE
14 GTEx Brain Cerebellum TRABD 0.32 0.01 lasso 8 0.07 5.3e-03 3.0 -5.5 4.3e-08 0.18 0.10 0.08 TRUE
15 GTEx Brain Hypothalamus BRD1 0.36 -0.01 lasso 11 -0.01 5.0e-01 -7.5 -6.5 5.6e-11 0.11 0.03 0.67 FALSE
16 GTEx Breast Mammary Tissue ALG12 0.24 -0.01 lasso 9 0.03 8.6e-03 -8.1 -6.7 2.2e-11 0.17 0.02 0.97 FALSE
17 GTEx Breast Mammary Tissue (Female) ALG12 0.20 -0.01 lasso 7 -0.01 8.6e-01 -6.7 -6.4 1.2e-10 0.15 0.04 0.70 FALSE
18 GTEx Breast Mammary Tissue (Female) CRELD2 0.07 -0.01 lasso 6 -0.01 6.5e-01 -6.0 -5.8 6.2e-09 0.11 0.07 0.12 FALSE
19 GTEx Colon Sigmoid CRELD2 0.20 0.07 lasso 6 0.04 1.7e-02 -7.0 -7.3 2.0e-13 0.11 0.02 0.90 FALSE
20 GTEx Colon Transverse ACR 0.18 0.01 lasso 7 0.04 4.0e-03 2.0 -7.2 7.3e-13 0.60 0.02 0.69 TRUE
21 GTEx Colon Transverse CRELD2 0.17 0.11 enet 9 0.10 2.2e-05 -6.6 -6.8 1.1e-11 0.07 0.61 0.33 FALSE
22 GTEx Esophagus Mucosa SELO 0.19 0.10 lasso 4 0.08 2.7e-06 -6.0 -6.1 1.3e-09 0.19 0.95 0.00 TRUE
23 GTEx Nerve Tibial ALG12 0.13 0.04 lasso 6 0.05 2.5e-04 -6.6 -6.5 8.5e-11 0.10 0.14 0.84 FALSE
24 GTEx Pancreas TRABD 0.22 -0.01 lasso 5 0.01 1.2e-01 -1.4 6.9 5.0e-12 -0.32 0.05 0.14 FALSE
25 GTEx Pancreas ALG12 0.22 0.15 lasso 4 0.15 7.9e-07 -5.7 -5.7 1.0e-08 0.09 0.76 0.16 FALSE
26 GTEx Pancreas RP3-402G11.26 0.20 0.04 lasso 4 0.02 4.1e-02 5.4 5.4 6.1e-08 -0.40 0.06 0.11 FALSE
27 GTEx Stomach SELO 0.13 0.08 lasso 2 0.05 2.1e-03 -6.1 -5.8 6.1e-09 0.18 0.21 0.05 FALSE
28 GTEx Thyroid SELO 0.15 0.06 lasso 3 0.06 2.1e-05 -6.1 -7.4 1.9e-13 0.22 0.64 0.05 TRUE
29 GTEx Whole Blood ZBED4 0.10 0.02 lasso 5 0.03 1.0e-03 -5.8 -6.8 1.3e-11 0.12 0.07 0.79 FALSE
30 NTR Blood CRELD2 0.02 0.02 lasso 2 0.02 2.9e-06 -6.6 -7.0 2.8e-12 0.10 0.08 0.92 FALSE
31 YFS Blood CRELD2 0.12 0.22 lasso 9 0.23 3.4e-73 -5.8 -6.3 2.6e-10 0.12 1.00 0.00 FALSE
32 YFS Blood PLXNB2 0.02 0.02 lasso 4 0.02 3.6e-07 4.7 -6.2 5.0e-10 0.40 0.95 0.04 TRUE
33 YFS Blood SBF1 0.11 0.04 blup 303 0.06 4.3e-19 5.2 6.0 1.9e-09 -0.38 1.00 0.00 FALSE
34 YFS Blood ZBED4 0.04 0.03 enet 15 0.04 4.4e-12 -7.9 -7.1 1.3e-12 0.11 0.03 0.97 FALSE
35 The Cancer Genome Atlas Bladder Urothelial Carcinoma SELO 0.05 0.01 blup 49 0.03 7.6e-04 -3.9 -5.4 6.2e-08 0.20 0.10 0.49 FALSE
36 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CRELD2 0.03 0.02 blup 38 0.02 3.2e-03 -5.9 -5.6 1.9e-08 0.09 0.23 0.18 FALSE
37 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SELO 0.04 0.03 lasso 3 0.03 2.0e-04 -6.9 -7.0 3.6e-12 0.23 0.00 0.98 FALSE
38 The Cancer Genome Atlas Brain Lower Grade Glioma ALG12 0.03 0.00 blup 43 0.02 2.8e-03 -7.8 -7.1 9.4e-13 0.12 0.02 0.84 FALSE
39 The Cancer Genome Atlas Lung Adenocarcinoma SELO 0.04 0.02 enet 7 0.03 3.5e-04 -6.0 -5.3 1.2e-07 0.08 0.15 0.57 FALSE
40 The Cancer Genome Atlas Prostate Adenocarcinoma CRELD2 0.04 0.06 lasso 1 0.06 1.7e-06 -5.5 -5.5 3.6e-08 0.12 0.88 0.09 FALSE
41 The Cancer Genome Atlas Prostate Adenocarcinoma SELO 0.07 0.04 blup 49 0.03 2.2e-04 -6.1 -7.0 2.0e-12 0.24 0.06 0.78 TRUE
42 The Cancer Genome Atlas Skin Cutaneous Melanoma BRD1 0.17 -0.01 blup 45 0.01 1.4e-01 -4.2 5.4 5.4e-08 -0.09 0.01 0.26 FALSE
43 The Cancer Genome Atlas Thyroid Carcinoma SELO 0.07 0.06 lasso 5 0.05 5.9e-06 -6.1 -5.8 5.2e-09 0.19 0.12 0.84 FALSE