[Hub]/) : Traits : Heel T-Score : ← →

chr2:181,042,370-184,769,427

Best TWAS P=3.27e-32 · Best GWAS P=2.53e-32 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ITGA4	0.07	0.01	enet	15	0.04	3.1e-05	11.41	-7.6	3.0e-14	-0.63	0.09	0.76	FALSE
2	GTEx	Artery Aorta	UBE2E3	0.09	0.00	lasso	3	0.01	1.6e-01	11.08	10.6	2.8e-26	0.79	0.04	0.68	FALSE
3	GTEx	Artery Tibial	FRZB	0.14	0.04	enet	16	0.05	9.6e-05	-1.04	-5.1	2.9e-07	0.12	0.83	0.11	FALSE
4	GTEx	Artery Tibial	DUSP19	0.15	0.07	lasso	5	0.06	1.9e-05	4.00	5.3	1.2e-07	-0.12	0.93	0.00	TRUE
5	GTEx	Brain Cerebellum	UBE2E3	0.26	0.13	enet	11	0.21	9.4e-07	5.84	6.1	1.2e-09	0.48	0.26	0.30	FALSE
6	GTEx	Brain Cerebellum	RP11-438L19.1	0.28	0.01	lasso	7	0.02	9.8e-02	4.69	-5.8	9.0e-09	0.09	0.09	0.05	TRUE
7	GTEx	Brain Hippocampus	FTH1P20	0.18	0.02	lasso	6	0.00	4.3e-01	11.43	-11.0	4.8e-28	-0.88	0.04	0.55	FALSE
8	GTEx	Breast Mammary Tissue	FRZB	0.13	0.05	lasso	3	0.02	3.7e-02	-6.26	-7.7	1.6e-14	0.06	0.03	0.76	FALSE
9	GTEx	Esophagus Mucosa	FRZB	0.08	0.00	enet	12	0.02	2.1e-02	-3.55	-6.4	1.5e-10	0.10	0.01	0.93	TRUE
10	GTEx	Esophagus Mucosa	UBE2E3	0.07	0.02	enet	22	0.06	7.9e-05	-5.09	7.7	1.2e-14	0.62	0.14	0.76	FALSE
11	GTEx	Esophagus Muscularis	UBE2E3	0.10	0.09	lasso	3	0.08	2.2e-05	11.68	11.8	3.3e-32	0.97	0.01	0.98	TRUE
12	GTEx	Nerve Tibial	FRZB	0.26	0.26	lasso	4	0.26	2.1e-18	-9.58	-9.6	1.0e-21	0.05	0.00	1.00	TRUE
13	GTEx	Nerve Tibial	UBE2E3	0.09	0.03	lasso	3	0.03	6.4e-03	11.08	11.6	7.2e-31	0.89	0.03	0.94	FALSE
14	GTEx	Ovary	UBE2E3	0.25	0.09	lasso	8	0.10	1.5e-03	-6.90	7.9	3.7e-15	0.55	0.11	0.35	FALSE
15	GTEx	Skin Not Sun Exposed Suprapubic	UBE2E3	0.25	0.06	enet	39	0.12	2.5e-07	10.28	8.8	2.0e-18	0.72	0.02	0.98	FALSE
16	GTEx	Testis	NUP35	0.34	0.32	lasso	5	0.29	3.1e-13	5.64	-5.7	1.1e-08	0.04	1.00	0.00	FALSE
17	METSIM	Adipose	NUP35	0.06	0.00	bslmm	385	0.02	1.5e-04	-0.16	-5.7	1.5e-08	0.02	0.07	0.22	FALSE
18	NTR	Blood	UBE2E3	0.02	0.00	bslmm	446	0.00	1.1e-02	11.74	8.8	1.1e-18	0.79	0.01	0.94	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	NCKAP1	0.08	0.02	bslmm	441	0.02	3.5e-04	3.87	-6.1	1.2e-09	0.06	0.79	0.02	FALSE
20	The Cancer Genome Atlas	Breast Invasive Carcinoma	FRZB	0.06	0.03	lasso	5	0.05	2.8e-11	-9.58	-7.8	6.2e-15	0.07	0.00	1.00	TRUE
21	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FRZB	0.05	0.01	blup	64	0.03	6.9e-04	-1.28	-7.7	1.2e-14	0.11	0.07	0.14	FALSE
22	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	UBE2E3	0.02	0.00	blup	61	0.01	1.1e-02	-6.19	10.9	8.8e-28	0.88	0.01	0.80	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	UBE2E3	0.04	0.02	blup	61	0.02	1.4e-03	11.08	11.2	6.6e-29	0.86	0.01	0.88	FALSE
24	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	NCKAP1	0.07	0.09	lasso	3	0.07	3.4e-04	6.75	6.8	7.3e-12	-0.05	0.11	0.06	FALSE
25	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	FRZB	0.08	0.01	blup	64	0.05	8.1e-07	-9.58	-8.2	2.6e-16	0.11	0.00	0.96	TRUE
26	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	FRZB	0.23	0.08	enet	19	0.10	8.1e-05	-8.70	-6.0	2.0e-09	0.06	0.00	0.93	TRUE
27	The Cancer Genome Atlas	Prostate Adenocarcinoma	FRZB	0.13	0.01	lasso	5	0.05	1.3e-05	-1.28	-6.6	3.9e-11	0.08	0.02	0.96	FALSE
28	The Cancer Genome Atlas	Prostate Adenocarcinoma	UBE2E3	0.05	0.03	blup	61	0.03	4.0e-04	11.08	11.3	9.9e-30	0.91	0.02	0.96	FALSE
29	The Cancer Genome Atlas	Stomach Adenocarcinoma	FRZB	0.10	0.00	blup	64	0.03	1.6e-03	-8.82	-8.9	4.0e-19	0.15	0.04	0.28	FALSE