TWAS hub - NCKAP1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Liver	0.501	0.1250	0.00180	-0.007	NA	0.003	NA	0.012	5.8e-01	NA	0.25000	NA	0.14000
2	ROSMAP	Brain Pre-frontal Cortex	0.081	0.0268	0.00013	0.020	0.02	0.021	0.024	0.020	1.1e-03	0.0011	0.00089	0.00035	0.00110
3	TCGA	Liver Hepatocellular Carcinoma	0.074	0.0450	0.00780	0.092	0.03	0.038	NA	0.070	4.2e-05	0.0140	0.00680	NA	0.00034

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Reason for reducing amount of alcohol drunk: Health precaution	6.7	7.9	13.1	-2.2	2.4	-3.6
Breastfed as a baby	5.9	7.4	8.9	2.9	-3.0	2.3
Exposure to tobacco smoke outside home	5.9	7.8	10.7	-3.3	2.5	-2.6
Irritability	5.4	9.2	14.6	0.0	3.8	-3.6
Guilty feelings	5.1	7.7	12.7	1.0	3.6	-3.1
Tense / ‘highly strung’	4.9	8.2	14.8	-0.1	3.8	-3.1
Number of full brothers	4.7	5.9	8.8	3.0	-1.5	2.5
Neuroticism	4.6	11.2	18.5	-1.1	4.3	-3.7
Nervous feelings	4.4	8.3	11.1	-2.1	3.1	-3.3
Medication: Bendroflumethiazide	3.9	6.0	12.7	-3.6	1.3	-1.9
Worry (Nagel 2018)	3.8	8.0	12.6	-1.0	3.6	-3.2
Heel T-Score	3.8	30.1	46.9	2.5	-6.1	6.8
Medication: Omeprazole	3.8	4.6	7.8	-0.0	2.8	-2.4
Shortness of breath walking on level ground	3.7	4.3	7.2	-1.8	2.7	-1.6
Heel bone mineral density (BMD) T-score, automated (left)	3.6	8.1	13.6	0.6	-3.2	3.7
Neuroticism score	3.6	7.6	12.0	-0.4	3.5	-3.2
Qualifications: CSEs or equivalent	3.3	4.3	7.6	-2.8	2.1	-1.0
Hypertension (Self-reported)	3.3	9.2	12.3	-2.2	3.5	-3.3
Age when periods started (menarche)	3.2	7.6	14.5	-3.8	1.3	-2.6
Tinnitus: Yes, but not now, but have in the past	3.2	3.4	4.7	-2.2	1.5	-1.8
Hearing difficulty/problems: Yes	3.1	4.7	11.5	-0.1	3.4	-1.6
Glaucoma (self-reported)	3.1	3.7	5.3	1.1	-2.3	2.1
Suffer from ‘nerves’	3.1	4.9	8.7	-0.6	2.4	-3.0
Miserableness	3.1	5.3	10.0	-1.0	3.2	-2.2
High blood pressure	2.9	8.0	9.1	-2.5	3.0	-3.0
Neuroticism (Nagel 2018)	2.8	6.5	10.4	-0.3	3.2	-3.0
Number of children fathered	2.8	3.1	5.2	-0.7	1.9	-2.3
Comparative height size at age 10	2.8	15.4	36.6	6.0	-2.1	2.3
Trunk fat-free mass	2.7	15.5	41.0	6.4	-1.6	1.7
Trunk predicted mass	2.7	15.5	41.0	6.4	-1.6	1.7
Frequency of tenseness / restlessness in last 2 weeks	2.6	4.0	8.0	0.1	2.8	-2.0
Worrier / anxious feelings	2.6	4.9	9.9	-0.2	3.1	-2.2
Arm fat-free mass (right)	2.6	13.1	34.3	5.9	-1.5	1.7
Arm fat-free mass (left)	2.6	13.2	36.0	6.0	-1.0	1.6
Arm predicted mass (left)	2.6	13.0	35.0	5.9	-1.1	1.7
Arm predicted mass (right)	2.5	12.5	33.1	5.8	-1.3	1.7
Vascular/heart problems diagnosed by doctor	2.5	6.8	7.7	2.6	-2.4	2.8
Hair/balding pattern: Pattern 3	2.4	3.6	9.0	-0.9	1.0	-3.0
Whole body fat-free mass	2.4	13.6	35.6	6.0	-1.5	1.7
Ever had prostate specific antigen (PSA) test	2.4	2.8	4.8	1.3	1.4	-2.2
Alzheimer’s Disease (in mother)	2.3	2.7	7.3	2.7	0.8	0.3
Hand grip strength (left)	2.3	6.0	6.4	2.5	-2.4	2.5
Frequency of unenthusiasm / disinterest in last 2 weeks	2.3	3.1	4.5	0.5	2.1	-2.1
Heel bone mineral density (BMD) T-score, automated (right)	2.3	5.2	8.1	0.3	-2.9	2.7
Loneliness, isolation	2.3	3.2	4.8	-0.6	2.2	-2.1
Illnesses of father: None of the above (group 1)	2.3	2.8	3.6	1.8	-1.3	1.9
Whole body water mass	2.3	13.1	34.9	5.9	-1.4	1.6
Cardiovascular Disease	2.2	7.2	9.1	-2.1	2.8	-3.0
Hearing difficulty/problems with background noise	2.2	3.6	8.7	1.0	3.0	-1.0
Loud music exposure frequency	2.2	2.4	4.7	0.1	1.6	-2.2
Medication for pain relief, constipation, heartburn	2.2	3.8	6.3	-0.1	-2.3	2.5
Ever depressed for a whole week	2.2	2.7	6.7	0.7	1.0	-2.6
Basal cell carcinoma (self-reported)	2.2	2.6	3.0	-1.5	1.7	-1.6
Diabetes (mother)	2.1	2.7	4.3	-1.4	1.4	-2.1
Medication: Ibuprofen	2.1	2.6	5.2	-0.0	2.3	-1.6
Frequency of depressed mood in last 2 weeks	2.0	2.8	5.2	1.0	2.3	-1.5
Basal metabolic rate	2.0	11.1	29.7	5.5	-1.1	1.5
Medication: Omeprazole (e.g. Zanprol)	2.0	2.4	4.2	0.9	2.1	-1.5
Pain experienced in last month	2.0	3.3	8.0	-2.8	0.2	-1.4
Depression (Nagel 2018)	1.9	2.8	5.4	-0.1	1.7	-2.3
Ulcerative Colitis	1.9	2.8	5.7	2.4	-0.1	1.7
Standing height	1.9	19.0	31.5	5.6	-4.1	2.9
Osteoporosis (self-reported)	1.9	2.3	2.7	-1.5	1.4	-1.6
Medication: Metformin	1.8	2.6	4.9	0.2	1.7	-2.2
Average weekly fortified wine intake	1.8	2.1	3.0	1.7	-1.6	0.9
Alcohol intake versus 10 years previously	1.8	2.7	7.1	-0.4	-2.7	0.9
Medication: Ventolin 100micrograms inhaler	1.8	2.3	3.5	-1.8	-0.2	-1.9
Medication: Seretide 50 evohaler	1.8	2.1	6.1	-2.5	0.1	-0.5
Pain type(s) experienced in last month: Hip pain	1.8	2.2	4.2	2.1	1.5	-0.3
Schizophrenia vs Biploar Disorder	1.7	2.2	4.5	-2.1	-0.4	-1.4
Noisy workplace	1.7	2.1	6.0	-0.3	0.5	-2.4
Qualifications: A levels/AS levels or equivalent	1.7	3.7	7.4	2.7	-0.5	1.9
Medication: Ibuprofen (e.g. Nurofen)	1.7	2.1	4.3	0.5	2.1	-1.3
Depression (self-reported)	1.7	2.1	4.3	-0.8	1.1	-2.1
Medication: Paracetamol	1.7	2.8	3.2	1.7	1.8	-1.5
Knee pain experienced in last month	1.7	2.7	6.5	2.6	0.5	1.1
Illnesses of siblings: Diabetes	1.7	2.1	6.2	2.5	0.2	0.4
Back pain experienced in last month	1.7	2.5	3.4	1.7	-1.2	1.8
Wears glasses or contact lenses	1.7	1.9	3.3	1.2	-1.1	1.8
Height	1.6	31.4	52.9	7.3	-4.3	4.8
Leg fat-free mass (left)	1.6	8.7	23.0	4.8	-1.1	1.3
Sitting height	1.6	11.5	20.4	4.5	-2.3	3.0
Had other major operations	1.6	1.9	4.1	0.1	2.0	-1.3
Time employed in main current job	1.6	1.9	3.8	2.0	1.1	-0.7
Number of self-reported non-cancer illnesses	1.6	2.7	5.2	0.0	2.3	-1.7
Medication: Atenolol	1.5	1.9	2.5	-1.3	1.2	-1.6
Leg predicted mass (left)	1.5	8.2	22.0	4.7	-1.0	1.2
Hair/balding pattern: Pattern 4	1.5	3.5	5.5	2.4	-0.6	2.2
Leg fat-free mass (right)	1.5	7.8	20.7	4.5	-1.1	1.1
Leg predicted mass (right)	1.5	7.9	21.0	4.6	-1.2	1.2
Reaction Time	1.4	2.6	6.0	-0.3	2.5	-1.3
Eye problems/disorders: Diabetes related eye disease	1.4	1.5	1.8	-1.0	1.3	-1.4
Severe depression (siblings)	1.4	1.6	2.7	-0.5	1.4	-1.6
Impedance of arm (left)	1.4	6.3	17.7	-4.2	-1.0	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.6	4.2	2.1	0.4	0.6
Financial situation satisfaction	1.4	1.8	2.0	-1.2	1.4	-1.4
Commuting to job workplace: Cycle	1.4	1.7	3.5	0.1	1.9	-1.3
Maternal smoking around birth	1.3	1.9	5.2	-0.1	2.3	-0.7
Chronic bronchitis/emphysema (father)	1.3	1.5	4.0	0.7	2.0	-0.4
Illnesses of father: Heart disease	1.3	1.8	2.7	-1.7	0.2	-1.7
Number of operations (self-reported)	1.3	2.0	3.7	0.2	1.5	-1.9
Fed-up feelings	1.2	2.1	4.3	0.8	2.1	-1.2
Frequency of tiredness / lethargy in last 2 weeks	1.2	1.9	3.4	0.7	1.4	-1.8
Mouth/teeth dental problems: Bleeding gums	1.2	1.5	1.8	-1.3	1.4	-1.0
Worry too long after embarrassment	1.2	2.1	3.0	1.0	1.5	-1.7
Migraine (self-reported)	1.2	1.5	2.4	1.6	-0.4	1.4
Age at last live birth	1.2	1.8	3.3	-1.8	1.2	-0.7
Average weekly red wine intake	1.2	1.8	4.3	2.1	-0.6	0.9
Myopia	1.2	1.7	3.1	-0.9	-1.8	1.1
Impedance of whole body	1.2	6.1	18.1	-4.2	-0.6	-0.1
Medication for hormone replacement therapy	1.1	1.3	2.5	-0.3	1.6	-1.1
Medication: Simvastatin	1.1	1.7	2.7	0.6	-1.4	1.6
Weight	1.1	5.3	13.4	3.7	-0.8	1.4
Forced expiratory volume in 1-second (FEV1)	1.1	3.7	6.0	2.4	-1.6	1.7
Medication: Lansoprazole	1.1	1.3	2.5	1.6	-0.1	1.1
Eye problems/disorders: None of the above	1.1	1.3	2.5	-1.1	1.6	-0.5
Had major operations	1.1	1.3	3.0	0.9	-1.7	0.5
Eye problems/disorders: Cataract	1.1	1.2	2.0	0.5	-1.2	-1.4
Medication: Paracetamol	1.1	1.7	3.2	1.8	1.1	-0.9
Heart disease (siblings)	1.1	1.3	3.2	-0.2	-1.8	0.8
Depressed Affect (Nagel 2018)	1.0	2.1	3.5	0.7	1.9	-1.5
Schizophrenia (2018)	1.0	2.1	3.5	-1.1	1.3	-1.9
Lupus	1.0	1.4	2.2	-0.8	1.5	-1.2
Type 2 Diabetes (T2D) (2012)	1.0	1.2	3.5	0.2	1.9	-0.3
Blood Platelet Count	1.0	11.1	12.2	-3.4	3.1	-3.5
Fluid intelligence score	1.0	2.1	2.8	0.9	-1.6	1.7
Impedance of arm (right)	1.0	4.8	13.8	-3.7	-0.7	0.1
Illnesses of mother	1.0	1.3	3.0	-1.7	0.8	-0.5
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.1	6.5	2.5	-0.8	1.4
Peak expiratory flow (PEF)	1.0	2.4	3.7	0.9	-1.9	1.7
Headache pain in last month	1.0	1.7	2.0	-1.1	1.4	-1.4
Wheeze or whistling in the chest in last year	1.0	1.7	4.7	-0.3	2.2	-0.6
Qualifications: College or University degree	1.0	3.0	7.9	2.8	-0.7	0.8
Leg pain on walking	1.0	1.3	1.9	-0.7	1.4	-1.2
Illnesses of father: High blood pressure	1.0	1.3	1.5	-1.2	1.0	-1.2
Average weekly beer plus cider intake	1.0	1.4	2.4	-1.1	1.5	-0.8
Bipolar Disorder (2018)	0.9	1.5	3.1	1.8	0.4	1.1
Chronotype (morning person)	0.9	2.2	4.5	1.0	-1.0	2.1
Hand grip strength (right)	0.9	2.4	4.1	0.9	-2.0	1.5
Hair/balding pattern: Pattern 2	0.9	1.1	2.8	-0.4	-1.7	0.6
Forced vital capacity (FVC)	0.9	3.6	5.2	2.3	-1.4	1.9
Pulse wave reflection index	0.9	1.1	2.3	1.5	-1.0	-0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	1.8	1.2	0.4	-1.3
Breast cancer (self-reported)	0.9	1.1	1.6	1.3	-0.3	1.2
Medication: Aspirin	0.9	1.2	3.0	-1.7	0.4	-0.6
Eye problems/disorders: Glaucoma	0.9	1.0	1.6	0.4	-1.3	1.1
Alzheimer’s Disease (including proxy)	0.8	1.1	2.9	1.7	0.6	0.1
Irritable Bowel Disease (IBD)	0.8	1.8	3.0	-0.4	-1.7	1.5
Major Depression (MDD)	0.8	1.0	1.3	-1.0	0.8	-1.1
Neuroticism (2016)	0.8	1.2	2.6	0.4	1.6	-0.9
Ever used hormone-replacement therapy (HRT)	0.8	1.0	1.7	1.0	1.3	-0.5
Supplements: Zinc	0.8	0.9	2.0	1.4	-0.5	0.7
High blood pressure (mother)	0.8	1.1	2.9	-1.7	-0.4	-0.5
Ever unenthusiastic/disinterested for a whole week	0.8	0.9	1.9	0.9	0.4	-1.4
Father’s age at death	0.8	1.0	1.9	1.4	0.4	-1.0
Happiness	0.8	1.0	1.8	0.1	1.4	-1.0
Asthma	0.8	1.5	1.7	-1.3	1.3	-1.1
Comparative body size at age 10	0.8	2.3	4.8	1.3	-2.2	0.7
Pulse wave peak to peak time	0.8	0.9	1.3	-1.1	-0.6	1.0
Mouth/teeth dental problems: Loose teeth	0.8	0.9	2.6	0.3	0.4	-1.6
Asthma (self-reported)	0.8	1.5	2.5	-1.6	1.2	-0.9
Ever taken oral contraceptive pill	0.8	0.9	2.0	-0.8	1.4	-0.1
Tinnitus: Yes, now most or all of the time	0.8	0.9	2.3	1.5	-0.5	0.3
Fractured/broken bones in last 5 years	0.8	1.1	2.2	-1.5	0.4	-0.9
Respiratory disease	0.7	1.6	2.7	-0.8	1.6	-1.2
Other serious medical condition/disability diagnosed by doctor	0.7	1.0	1.5	0.2	-1.2	1.2
Vitamin and mineral supplements	0.7	0.9	1.8	0.8	-0.7	1.3
Townsend deprivation index at recruitment	0.7	1.0	2.2	-1.5	-0.1	0.9
Multivitamins +/- minerals	0.7	0.9	2.3	-0.0	0.6	-1.5
Pulse wave Arterial Stiffness index	0.7	0.9	2.0	1.4	0.3	-0.7
Forced vital capacity (FVC), Best measure	0.7	2.4	5.4	2.3	-0.5	1.2
Medication: Blood pressure	0.7	1.3	2.1	-1.1	0.8	-1.4
Mean time to correctly identify matches	0.7	1.3	2.5	-0.2	1.6	-1.2
Medication: Aspirin	0.7	0.9	2.6	-1.6	0.1	-0.3
Friendships satisfaction	0.7	0.9	1.1	1.0	-0.8	1.0
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	1.6	1.3	-0.8	1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	1.3	0.1	1.1	-1.1
Diastolic blood pressure, automated reading	0.7	2.1	5.0	0.6	2.2	-1.0
Crohns Disease (2017)	0.6	1.3	1.7	-1.0	-1.3	1.1
Age at First Birth	0.6	0.9	2.2	0.1	0.6	-1.5
Primary Biliary Cirrhosis	0.6	0.9	2.1	-0.3	-0.8	1.4
Medication: Levothyroxine sodium	0.6	0.9	1.3	-0.6	1.1	-1.1
Impedance of leg (left)	0.6	2.7	8.0	-2.8	-0.2	0.5
Financial difficulties in last 2 years	0.6	0.8	1.6	0.1	0.9	-1.3
Diabetes (self-reported)	0.6	0.9	2.6	1.6	-0.0	-0.2
Exposure to tobacco smoke at home	0.6	0.6	1.8	0.3	-0.2	1.3
Birth weight of first child	0.6	1.0	1.6	1.3	-0.8	0.9
High blood pressure (siblings)	0.6	0.9	1.7	-1.3	0.8	-0.6
Health satisfaction	0.6	0.8	1.8	1.4	0.6	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	2.6	1.6	0.9	-0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	1.4	0.5	1.2	-0.4
Medication for cholesterol	0.6	0.9	1.9	0.5	-1.4	0.8
Medication: Blood pressure	0.6	1.1	1.9	-1.1	1.4	-0.5
Cholesterol lowering medication	0.6	0.9	1.4	-1.2	-0.9	0.7
Ulcerative Colitis (UC)	0.5	1.0	1.4	0.2	-1.2	1.2
Prostate Cancer	0.5	0.7	1.6	-1.3	-0.6	0.4
Crohns Disease (2012)	0.5	0.7	2.1	0.2	-0.3	1.4
Medication: Co-codamol	0.5	0.6	1.1	-0.9	0.2	1.1
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	0.8	-0.8	0.7	-0.9
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.1	-0.7	-0.6	-1.0
Mouth/teeth dental problems	0.5	0.7	1.7	1.3	-0.0	0.7
Heart attack	0.5	0.7	1.7	-0.1	-1.3	0.6
Hip circumference	0.5	2.0	5.3	2.3	0.5	0.6
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	0.9	0.9	1.0	-0.0
Mouth/teeth dental problems: Dentures	0.5	0.9	1.4	-1.2	0.9	-0.8
Lung cancer (father)	0.5	0.6	1.3	0.1	-1.1	0.7
Neck or shoulder pain in last month	0.5	0.7	1.8	1.3	0.5	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.1	-0.7	-1.1	-0.4
Alcohol intake frequency.	0.5	1.0	3.1	-1.8	0.2	-0.2
Qualifications: nursing, teaching	0.5	0.8	1.3	1.1	-0.8	0.7
Mineral and other dietary supplements	0.5	0.7	1.2	1.1	0.9	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	2.8	0.2	1.7	-0.4
Commuting to job workplace: Public transport	0.5	0.6	0.9	-1.0	-0.9	-0.0
Medication: Lisinopril	0.5	0.6	1.4	-0.6	1.2	-0.3
Age started oral contraceptive pill	0.5	0.6	1.7	-0.0	-1.3	0.4
Ovarian Cancer	0.4	0.5	0.8	-0.9	-0.5	-0.7
Mean Putamen Volume	0.4	0.5	0.7	-0.8	-0.8	0.1
Fasting Glucose	0.4	0.4	1.2	-1.1	0.0	-0.4
Schizophrenia (2014)	0.4	1.0	1.5	-0.9	0.8	-1.2
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.3	0.0	0.8	-1.2
Lung FEV1/FVC ratio	0.4	2.1	3.8	0.8	-1.9	1.4
Stomach or abdominal pain in last month	0.4	0.6	1.0	1.0	0.7	-0.3
Had menopause	0.4	0.5	1.2	1.1	-0.5	-0.1
Falls in the last year	0.4	0.5	0.7	-0.8	0.7	0.6
Pulse rate	0.4	0.6	1.7	-1.3	0.1	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.7	1.9	0.2	-0.1	-1.4
Leg fat mass (right)	0.4	1.7	4.4	2.1	0.4	0.8
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.0	-1.0	-0.7	0.3
Handedness (chirality/laterality): Left-handed	0.4	0.4	0.5	-0.6	0.7	-0.6
Diabetes diagnosed by doctor	0.4	0.6	0.8	0.7	0.6	-0.9
Osteoarthritis (self-reported)	0.4	0.5	1.1	1.1	0.5	-0.1
Mother’s age at death	0.4	0.5	0.8	0.1	-0.9	-0.8
Leg fat mass (left)	0.4	1.4	3.4	1.9	0.6	0.7
Bipolar Disorder or Schizophrenia	0.3	0.7	1.5	0.3	1.2	-0.7
Intelligence (Savage-Jansen 2018)	0.3	0.8	1.8	0.5	-1.4	0.7
Bipolar Disorder (2011)	0.3	0.3	0.7	0.8	0.4	-0.0
HbA1C	0.3	0.4	0.5	-0.7	0.7	-0.4
Ever had hysterectomy (womb removed)	0.3	0.4	0.7	0.5	-0.8	-0.3
Systolic blood pressure, automated reading	0.3	0.9	2.3	1.5	0.5	0.6
Impedance of leg (right)	0.3	1.6	4.0	-2.0	-0.3	0.8
Current tobacco smoking	0.3	0.6	0.9	-0.9	0.9	-0.0
Relative age voice broke	0.3	0.5	1.4	-0.2	-0.2	-1.2
Taking other prescription medications	0.3	0.5	0.8	0.4	0.7	-0.9
Waist circumference	0.3	1.0	2.5	1.6	0.7	0.3
Alcohol usually taken with meals	0.3	0.5	0.8	0.9	-0.8	0.4
Medication: Ramipril	0.3	0.4	0.8	0.5	0.9	0.5
Arm fat mass (right)	0.3	1.2	3.2	1.8	0.4	0.5
Ever highly irritable/argumentative for 2 days	0.3	0.3	0.6	-0.5	0.8	-0.3
Birth weight	0.3	0.7	1.3	1.1	-0.5	0.7
Heart disease (mother)	0.3	0.4	0.6	0.6	-0.5	0.8
Whole body fat mass	0.3	1.1	2.3	1.5	-0.3	0.9
Commuting to job workplace: Walk	0.3	0.4	0.5	-0.7	0.4	-0.6
Medication: Gliclazide	0.3	0.4	0.6	-0.8	-0.0	-0.7
Smoking status: Current	0.3	0.5	0.8	-0.8	0.9	0.1
Arm fat mass (left)	0.3	1.3	3.3	1.8	0.3	0.6
Supplements: Fish oil (including cod liver oil)	0.3	0.4	0.7	-0.8	-0.1	0.8
Alcohol drinker status: Never	0.3	0.4	0.9	-1.0	0.4	-0.2
Risk taking	0.3	0.5	1.3	-0.3	-1.1	-0.1
Unable to work because of sickness or disability	0.3	0.4	0.8	0.4	-0.4	0.9
Alzheimer’s Disease (in father)	0.2	0.2	0.4	-0.4	0.6	0.0
Coronary Artery Disease (CAD)	0.2	0.2	0.4	-0.4	-0.6	-0.4
Rheumatoid Arthritis	0.2	0.3	0.8	0.3	0.3	-0.9
Triglycerides	0.2	0.3	0.6	-0.6	0.8	0.0
Blood Red Count	0.2	1.7	3.9	-2.0	0.4	-1.0
Hair Pigment	0.2	5.9	9.5	2.4	-1.6	3.1
Number of treatments/medications taken	0.2	0.3	0.5	-0.2	0.7	-0.6
Sensitivity / hurt feelings	0.2	0.4	0.7	0.4	0.9	-0.5
Angina	0.2	0.2	0.7	-0.0	0.1	0.8
Diabetes (father)	0.2	0.2	0.3	0.6	0.4	0.5
Body mass index (BMI)	0.2	0.9	1.7	1.3	1.1	0.2
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	0.5	0.3	0.7	0.4
Length of working week for main job	0.2	0.2	0.4	0.7	-0.4	0.3
Blood clot in the leg (DVT)	0.2	0.2	0.4	-0.7	0.0	0.4
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	0.4	0.6	-0.5	0.6
Gout (self-reported)	0.2	0.3	1.0	-0.1	1.0	0.0
Medication: Amlodipine	0.2	0.3	0.5	-0.6	0.7	0.2
Chronic bronchitis/emphysema (mother)	0.2	0.3	0.7	0.8	-0.4	0.2
Leg fat percentage (right)	0.2	0.8	1.5	0.8	1.2	0.6
Angina (self-reported)	0.2	0.2	0.7	0.2	0.0	0.8
Pulse rate, automated reading	0.2	0.7	1.6	-1.3	0.3	0.5
Number of full sisters	0.2	0.3	0.6	-0.3	0.2	-0.8
Overall health rating	0.2	0.5	1.1	-0.4	0.2	-1.1
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.6	0.2	0.8	-0.3
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.3	0.5	0.5	-0.4
Smoking status: Previous	0.2	0.3	0.6	0.2	-0.8	0.4
High cholesterol (Self-reported)	0.2	0.3	0.6	0.6	-0.7	0.0
Medication: Atorvastatin	0.2	0.2	0.6	-0.8	-0.2	-0.2
Leg fat percentage (left)	0.2	0.8	2.3	0.3	1.5	0.3
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.8	-0.1	-0.9	0.1
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.5	-0.4	-0.4	0.7
Alcohol drinker status: Previous	0.2	0.2	0.4	-0.6	0.4	0.1
Verbal and Numeric Reasoning (VNR)	0.1	0.1	0.2	0.4	-0.5	0.2
Body Mass Index (BMI) (2010)	0.1	0.2	0.3	-0.4	0.1	-0.6
HDL Cholesterol	0.1	0.2	0.5	0.7	0.1	-0.4
LDL Cholesterol	0.1	0.2	0.2	-0.5	0.4	-0.1
Blood Eosinophil Count	0.1	0.5	1.4	0.4	1.2	-0.3
Blood White Count	0.1	0.8	1.3	-1.1	0.3	-1.0
BMI	0.1	0.8	1.3	1.1	0.7	0.8
Waist Hip Ratio (WHR)	0.1	0.2	0.6	-0.4	0.7	0.2
Systolic Blood Pressure	0.1	0.7	1.3	0.4	1.2	0.8
Smoking Status	0.1	0.3	0.6	-0.2	0.4	0.7
Allergy or Eczema	0.1	0.1	0.4	0.6	-0.2	0.0
Lung FVC	0.1	0.4	0.6	-0.7	-0.0	0.8
Tanning	0.1	0.9	1.7	-0.9	-1.3	0.5
Average weekly spirits intake	0.1	0.1	0.3	-0.1	-0.6	0.1
Relative age of first facial hair	0.1	0.2	0.4	0.5	-0.6	-0.1
Pack years adult smoking proportion	0.1	0.2	0.2	0.5	0.4	0.3
Trunk fat percentage	0.1	0.3	0.6	-0.8	0.5	0.1
Supplements: Glucosamine	0.1	0.2	0.2	0.4	-0.4	-0.4
Trunk fat mass	0.1	0.4	0.9	1.0	-0.2	0.6
Number of incorrect matches in round	0.1	0.1	0.2	0.2	-0.0	-0.5
Past tobacco smoking	0.1	0.2	0.3	0.0	0.5	-0.4
Qualifications: None of the above	0.1	0.3	0.7	-0.8	0.3	0.2
Allergy	0.1	0.2	0.4	0.6	-0.5	-0.4
Illnesses of siblings	0.1	0.2	0.3	-0.6	0.3	-0.3
Arm fat percentage (right)	0.1	0.5	1.5	0.2	1.2	-0.0
Medication: Cholesterol lowering	0.1	0.1	0.2	0.5	-0.2	0.4
Prospective memory result	0.1	0.1	0.3	-0.1	0.3	-0.5
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.4	0.5	0.7	-0.2
Hypothyroidism/myxoedema (self-reported)	0.1	0.1	0.2	-0.5	-0.3	-0.3
Age at first live birth	0.1	0.1	0.2	-0.5	-0.4	-0.1
Emphysema/chronic bronchitis	0.1	0.1	0.4	-0.6	-0.0	-0.1
Family relationship satisfaction	0.1	0.2	0.3	0.5	-0.5	0.1
Supplements: Vitamin C	0.1	0.1	0.1	0.2	0.1	0.4
Arm fat percentage (left)	0.1	0.4	1.1	-0.2	1.0	-0.1
Mood swings	0.1	0.1	0.2	-0.4	0.2	-0.3
Long-standing illness, disability or infirmity	0.1	0.1	0.3	-0.0	0.6	-0.3
Ever had bowel cancer screening	0.1	0.2	0.3	-0.2	0.4	-0.5
Average weekly champagne plus white wine intake	0.1	0.1	0.3	-0.1	-0.0	-0.5
Hearing aid user	0.1	0.1	0.2	-0.3	0.1	0.4
Ever smoked	0.1	0.2	0.5	-0.3	-0.2	-0.7
Supplements: Calcium	0.1	0.1	0.1	0.1	0.2	0.4
Pack years of smoking	0.1	0.2	0.5	0.1	-0.1	0.7
Breast Cancer	0.0	0.0	0.0	-0.0	-0.1	-0.2
Hypothyroidism (self reported)	0.0	0.1	0.1	-0.3	0.3	-0.3
Serious illness, injury or assault to yourself	0.0	0.0	0.0	-0.2	-0.1	-0.2
Hayfever, allergic rhinitis or eczema	0.0	0.0	0.1	0.2	0.3	0.2
Pain all over the body in last month	0.0	0.0	0.0	-0.0	0.1	0.2
Number of live births	0.0	0.0	0.1	0.2	-0.2	-0.2
Body fat percentage	0.0	0.2	0.4	-0.3	0.7	0.2
Medication: Allopurinol	0.0	0.1	0.1	0.3	0.2	-0.2
Chest pain or discomfort	0.0	0.0	0.0	-0.2	0.2	0.1

Hub : Genes

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