TWAS hub - ITGA4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0670	0.0250	0.00028	0.008	0.030	0.036	0.030	0.014	2.9e-02	1.2e-04	3.1e-05	1.3e-04	6.3e-03
2	GTEx	Cells Transformed fibroblasts	0.1550	0.0550	0.00120	0.121	NA	0.070	NA	0.091	2.3e-09	NA	6.2e-06	NA	2.7e-07
3	GTEx	Esophagus Muscularis	0.1160	0.0470	0.00320	0.029	NA	0.034	NA	0.044	7.2e-03	NA	3.8e-03	NA	1.1e-03
4	METSIM	Adipose	0.0427	0.0183	0.00270	-0.002	0.006	0.000	0.006	-0.001	9.3e-01	3.7e-02	3.7e-01	3.7e-02	5.8e-01
5	NTR	Blood	0.0307	0.0116	0.00013	0.007	0.016	0.014	0.018	0.009	1.5e-03	4.5e-06	2.3e-05	1.0e-06	5.5e-04
6	TCGA	Bladder Urothelial Carcinoma	0.0820	0.0430	0.00360	0.000	0.043	0.023	NA	0.007	3.1e-01	1.5e-04	4.8e-03	NA	7.9e-02
7	TCGA	Colon Adenocarcinoma	0.0550	0.0290	0.00310	0.023	0.020	0.016	NA	0.011	1.7e-02	2.4e-02	3.8e-02	NA	7.2e-02
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.0418	0.0274	0.00650	-0.001	0.014	-0.001	NA	0.001	4.2e-01	8.9e-03	5.1e-01	NA	2.1e-01
9	TCGA	Pancreatic Adenocarcinoma	0.1860	0.0860	0.00055	0.065	0.086	0.062	NA	0.079	1.1e-03	1.8e-04	1.3e-03	NA	3.4e-04
10	TCGA	Prostate Adenocarcinoma	0.0382	0.0207	0.00100	0.030	0.028	0.035	NA	0.038	3.9e-04	6.2e-04	1.4e-04	NA	7.5e-05
11	TCGA	Thyroid Carcinoma	0.0360	0.0190	0.00190	0.034	0.027	0.002	NA	0.026	2.7e-04	1.1e-03	2.1e-01	NA	1.4e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Blood White Count	7.4	54.9	169.0	-3.1	3.0	1.8	-9.7	-13.0	-10.6	2.7	-3.8	-6.7	-8.1	8.6
Had major operations	3.0	3.6	11.3	-0.2	-1.8	0.4	2.6	1.1	3.4	0.0	2.6	2.9	1.0	-0.1
Past tobacco smoking	2.7	5.0	23.2	-4.8	-0.7	0.3	-2.9	-4.2	-0.4	0.8	0.0	0.5	-0.8	1.9
Breastfed as a baby	2.6	3.2	9.9	-1.1	0.4	1.8	2.5	1.8	3.1	1.1	0.6	1.8	2.2	-1.2
Crohns Disease (2017)	2.4	5.4	21.7	0.4	-0.7	-0.8	2.7	4.7	2.4	-0.3	1.3	2.0	2.7	-3.1
Ever smoked	2.4	4.1	16.2	4.0	0.2	0.6	2.9	3.9	0.9	0.1	0.2	-0.2	1.4	-1.6
Smoking Status	2.3	5.5	21.6	4.6	0.7	1.9	3.5	3.8	1.2	0.5	0.3	-0.2	2.2	-1.2
Average weekly fortified wine intake	2.3	2.7	9.7	0.3	-1.3	-3.1	-0.8	0.5	-0.8	-2.0	-1.9	-1.7	0.3	-2.5
Eye problems/disorders: None of the above	2.3	2.7	10.5	0.7	-0.4	1.2	1.1	0.6	-1.2	3.2	2.1	0.9	-0.6	2.8
Medication: Gliclazide	2.3	2.6	6.6	0.7	1.0	2.2	2.0	1.1	0.2	2.6	2.3	1.5	0.2	1.8
Irritable Bowel Disease (IBD)	2.2	5.1	19.0	-0.8	-0.5	-1.3	2.4	4.4	2.3	-0.7	1.1	2.7	2.2	-3.2
Smoking status: Previous	2.1	3.1	13.4	3.6	-0.3	-0.8	2.1	3.7	-0.1	-0.9	0.0	-0.6	0.2	-1.4
Fed-up feelings	2.0	3.7	11.5	1.6	1.2	3.4	3.2	0.9	0.4	2.7	0.7	0.1	2.0	1.5
Stomach or abdominal pain in last month	2.0	2.5	7.3	0.4	0.4	2.7	2.7	0.9	1.5	1.8	0.4	1.9	1.5	0.5
Medication: Ibuprofen	2.0	2.4	10.9	-3.3	-2.2	-1.1	-1.3	-2.2	-0.4	-0.7	-1.5	0.2	-0.6	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.0	2.3	12.7	0.2	-0.2	-0.9	-0.3	-1.0	0.7	-3.6	-2.0	-0.9	-0.3	-2.3
Hair/balding pattern: Pattern 3	1.9	2.9	7.9	1.5	-2.3	-2.8	-1.6	-0.5	-1.7	-1.5	-2.1	-1.2	-1.7	-0.1
Length of working week for main job	1.9	2.1	6.1	-0.1	-0.3	-1.6	-0.3	-0.6	-0.3	-2.0	-2.5	-2.1	0.3	-2.4
Supplements: Zinc	1.8	2.0	10.0	-2.2	0.6	-1.4	-3.2	0.1	-0.5	-1.4	-0.8	-0.3	-0.5	-1.3
Medication: Ventolin 100micrograms inhaler	1.8	2.4	6.7	1.1	-0.4	-2.2	-0.5	-0.3	-1.3	-2.6	-2.2	-1.4	-0.5	-2.0
Crohns Disease (2012)	1.7	2.8	10.0	0.8	-1.7	-0.3	2.2	3.2	1.3	0.2	-0.3	0.4	2.1	-2.4
Peak expiratory flow (PEF)	1.7	3.8	7.6	-1.8	-2.1	-1.3	-2.0	-1.8	-2.1	-2.0	-2.8	-2.7	-0.2	-1.6
Chronic bronchitis/emphysema (mother)	1.7	2.0	5.7	1.0	-1.2	-0.0	2.3	2.3	1.0	0.5	0.0	0.9	2.4	-1.1
Smoking status: Current	1.7	2.7	10.2	3.2	1.5	2.2	1.9	1.8	0.7	1.7	0.4	0.2	1.4	0.4
Heart disease (siblings)	1.7	2.1	6.6	0.8	0.8	-0.3	2.0	1.8	2.6	-0.4	0.6	0.8	1.8	-1.8
Bipolar Disorder (2011)	1.6	1.5	6.6	2.6	-0.6	-1.5	0.8	2.5	-0.7	0.2	-0.2	-0.0	0.3	-0.6
Hypothyroidism (self reported)	1.6	3.6	13.0	-2.5	-1.3	0.4	-1.8	-3.6	-2.4	1.1	-1.9	-2.1	-0.4	1.1
Chronotype (morning person)	1.6	3.7	8.4	0.9	1.0	-2.4	-1.8	-2.1	-2.9	-1.8	-1.7	-2.5	-2.2	-0.2
Chest pain or discomfort	1.6	2.3	8.2	0.2	0.8	-1.6	0.5	-0.2	-0.1	-2.9	-2.0	-1.4	0.6	-2.8
Supplements: Vitamin C	1.6	1.9	7.5	-1.2	-0.3	-2.7	-0.9	-1.0	0.4	-2.0	-1.1	-0.2	0.1	-2.1
Current tobacco smoking	1.5	2.5	10.7	3.3	1.4	2.2	2.0	1.5	0.4	1.5	0.1	-0.2	1.1	0.4
Multivitamins +/- minerals	1.5	2.0	6.9	-0.4	-1.6	-1.2	-1.2	-0.0	-1.7	-0.6	-2.2	-2.6	0.2	-0.8
Medication: Lansoprazole	1.5	1.7	6.2	2.5	-1.2	-1.0	1.4	0.4	0.9	-2.1	-1.0	-1.0	-0.1	-1.1
Exposure to tobacco smoke outside home	1.5	2.0	8.2	2.9	-0.6	-1.0	2.1	1.5	0.6	-0.5	-0.4	-0.7	1.8	-1.3
Medication: Omeprazole	1.5	1.8	5.4	1.1	-0.4	-0.6	2.3	0.9	1.6	-2.1	-0.3	0.8	0.6	-1.9
Commuting to job workplace: Walk	1.5	1.6	4.2	2.0	0.6	0.3	0.9	1.4	0.1	2.0	1.4	1.3	-0.3	1.5
Illnesses of father: None of the above (group 1)	1.5	1.8	4.5	-0.5	-0.5	1.6	2.1	1.1	1.8	1.8	0.8	0.6	1.5	1.0
Average weekly champagne plus white wine intake	1.5	2.0	4.8	-1.7	0.9	2.2	1.0	1.0	2.0	1.3	1.1	1.2	1.8	0.8
Mother’s age at death	1.5	1.8	4.9	1.4	-0.7	-2.2	-0.7	0.8	-1.5	-1.1	-1.9	-1.5	-0.4	-1.4
Financial situation satisfaction	1.5	1.9	5.6	2.4	-0.4	-0.4	2.3	1.3	-0.5	-0.5	-0.8	-1.5	1.6	-1.5
Pack years of smoking	1.5	2.2	6.0	1.7	2.1	2.1	2.5	1.2	1.2	1.0	0.6	0.8	1.4	0.1
Depressed Affect (Nagel 2018)	1.4	3.0	9.4	1.1	0.1	2.8	2.0	0.5	0.3	3.1	1.5	1.0	0.8	2.5
Reaction Time	1.4	2.6	5.9	0.2	-1.6	-2.4	-0.8	-1.3	-0.2	-2.0	-2.2	-2.4	0.4	-1.8
Type 2 Diabetes (T2D) (2018)	1.4	2.6	6.2	2.0	-0.8	-1.3	1.6	0.2	-1.1	-1.5	-2.4	-2.5	0.3	-2.0
Hair/balding pattern: Pattern 4	1.4	3.3	8.0	2.0	2.1	2.5	2.8	0.9	0.9	2.0	1.8	1.5	1.0	1.0
Birth weight of first child	1.4	2.5	11.7	-3.4	0.6	-0.2	0.4	-0.8	1.2	-0.9	-0.5	-1.2	2.3	-2.4
Loud music exposure frequency	1.4	1.6	4.0	0.7	-1.7	-1.4	0.7	0.1	-0.1	-1.9	-0.9	-1.7	0.2	-2.0
Handedness (chirality/laterality): Left-handed	1.4	1.7	5.0	0.9	0.9	1.8	0.9	0.9	-1.0	2.2	1.8	0.6	0.4	1.5
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	4.1	1.9	0.4	-0.7	0.3	1.2	1.6	-1.8	0.1	-0.5	1.1	-2.0
Mineral and other dietary supplements	1.4	1.9	4.9	0.1	1.8	1.6	1.3	-1.4	0.9	0.3	2.0	2.2	-0.6	1.3
Medication: Atorvastatin	1.4	1.7	6.8	2.6	1.4	0.2	2.4	0.2	0.7	-0.3	-0.9	0.1	1.4	-1.0
Alzheimer’s Disease (in father)	1.3	1.4	4.9	1.4	1.0	0.1	-0.7	-0.2	-1.8	-0.9	-2.2	-1.3	-0.8	-0.3
Primary Biliary Cirrhosis	1.3	1.9	4.3	1.8	2.1	-1.3	-1.3	0.4	-1.9	-1.6	-0.8	-1.5	-0.8	-0.6
Hayfever, allergic rhinitis or eczema	1.3	2.9	5.4	2.2	-2.3	-2.2	0.7	1.5	0.3	-2.2	-1.6	-1.1	-0.2	-2.2
Falls in the last year	1.3	1.7	3.9	1.1	0.8	0.7	1.2	0.8	1.9	-1.8	0.1	1.3	1.5	-2.0
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.6	4.8	-2.2	-1.8	-1.3	-0.9	-1.7	-0.6	-0.7	-1.8	-0.3	-0.5	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	2.1	9.2	3.0	-1.0	0.3	2.5	1.2	-0.9	1.2	-0.2	-0.6	1.3	-0.3
Hypothyroidism/myxoedema (self-reported)	1.3	2.5	11.4	-2.8	-0.9	0.7	-1.2	-3.4	-1.2	0.5	-1.6	-1.1	0.2	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.3	1.6	4.8	2.2	-0.4	0.2	0.8	2.1	-1.3	0.3	-1.3	-1.5	0.7	-1.0
Illnesses of father: Heart disease	1.3	1.9	6.2	-1.0	0.1	-2.4	-1.2	-1.4	0.5	-2.5	0.7	0.3	-0.8	-1.7
Osteoporosis (self-reported)	1.3	1.6	5.4	0.5	0.7	1.0	0.0	1.5	0.6	1.2	2.0	2.3	-1.1	1.1
Number of self-reported non-cancer illnesses	1.3	2.3	6.1	2.1	-0.6	-1.2	1.5	-0.4	0.5	-2.5	-1.7	-0.8	0.9	-2.4
Vascular/heart problems diagnosed by doctor	1.3	3.4	17.1	-4.1	-1.8	-0.7	-3.7	-0.1	-1.0	0.7	-0.2	-0.5	-1.3	0.4
Heel T-Score	1.2	9.3	57.8	-7.6	-2.4	-1.6	-4.5	-3.6	-1.1	0.9	-0.3	-0.3	-0.3	0.6
Number of treatments/medications taken	1.2	2.1	6.0	0.4	0.8	0.8	2.5	-1.5	1.9	-1.8	-2.0	0.3	0.5	-1.5
Ever used hormone-replacement therapy (HRT)	1.2	1.5	6.4	2.5	0.1	1.0	2.5	1.7	-0.2	-0.1	-0.4	-0.4	-0.4	-0.0
Pack years adult smoking proportion	1.2	1.8	4.8	1.8	1.9	1.9	2.2	0.9	1.0	0.8	0.2	0.4	1.5	-0.4
Age when periods started (menarche)	1.2	2.8	12.2	-2.3	0.3	0.6	-3.5	-1.1	1.2	0.8	1.8	2.1	0.0	1.2
High blood pressure (mother)	1.2	1.7	3.9	1.9	-0.9	-2.0	0.2	-0.5	-0.7	-1.8	-1.7	0.0	-1.1	-1.3
Financial difficulties in last 2 years	1.2	1.7	5.0	1.8	1.6	-0.2	1.0	0.3	0.2	-1.4	-1.8	-0.5	1.0	-2.2
Diabetes (self-reported)	1.2	1.9	5.8	1.3	1.3	-0.6	2.0	0.0	-0.1	-1.7	-1.7	-1.3	0.6	-2.4
Noisy workplace	1.2	1.4	4.2	-0.1	-1.1	-0.0	1.6	1.3	0.9	-0.2	-1.3	-0.7	1.8	-2.0
Ever highly irritable/argumentative for 2 days	1.2	1.5	3.7	-0.5	-1.9	0.8	1.5	0.0	0.8	1.3	1.7	1.8	0.5	0.9
Medication: Amlodipine	1.2	1.7	6.8	2.6	1.7	1.0	2.4	0.1	1.2	-0.3	0.3	0.4	0.0	0.0
Medication: Allopurinol	1.2	1.6	5.1	2.1	-1.5	0.7	2.3	2.1	0.0	0.8	0.2	0.0	-0.0	0.6
Ever had bowel cancer screening	1.2	1.4	3.9	0.6	0.1	2.0	1.8	1.8	1.1	0.4	-0.7	0.1	1.6	-0.4
Osteoarthritis (self-reported)	1.2	1.5	5.2	1.0	-0.2	-0.3	-0.9	-0.3	-1.9	-1.2	-2.3	-1.9	-0.8	-0.6
Ever taken oral contraceptive pill	1.2	1.3	3.5	1.6	-1.5	-0.8	1.5	1.9	-0.1	-0.9	-0.3	-0.9	0.5	-1.2
Allergy or Eczema	1.1	2.9	8.6	2.9	-1.5	-0.6	1.9	2.9	1.2	-1.6	-0.7	-0.0	0.4	-1.9
Townsend deprivation index at recruitment	1.1	1.5	10.1	3.2	1.4	0.4	1.1	0.2	-0.7	0.7	0.9	0.8	-0.5	0.6
High blood pressure	1.1	3.2	13.6	3.7	1.8	0.7	3.7	0.1	1.1	-0.5	0.3	0.7	1.3	-0.3
Had other major operations	1.1	1.4	3.9	1.1	-0.8	-0.2	1.1	1.1	1.7	-1.1	-0.5	-0.5	1.4	-2.0
Forced expiratory volume in 1-second (FEV1)	1.1	3.7	7.2	-2.4	-2.1	-1.8	-2.3	-0.3	-1.6	-1.7	-2.7	-1.9	0.4	-2.2
Medication: Blood pressure	1.1	2.0	8.0	2.8	2.1	0.0	1.9	-0.8	0.6	-1.4	-0.8	-0.5	0.9	-1.1
Heart disease (mother)	1.1	1.3	7.3	0.7	-0.1	-0.0	2.7	-0.6	1.2	-0.4	0.9	1.5	0.5	-1.1
Medication: Aspirin	1.1	1.5	6.3	2.5	1.2	-0.7	0.8	0.0	-0.2	-2.4	-0.5	-0.4	-0.9	-0.8
Hypertension (Self-reported)	1.1	3.0	12.3	3.5	1.6	0.8	3.5	-0.4	1.4	-0.4	0.5	0.9	1.2	-0.1
Eye problems/disorders: Glaucoma	1.1	1.3	4.2	-0.2	0.6	-1.4	-0.3	-0.3	0.1	-1.8	-2.1	-1.2	0.4	-1.7
Number of operations (self-reported)	1.1	1.6	5.5	-0.7	-0.7	0.0	1.2	-0.1	2.4	-1.7	-0.5	0.7	1.5	-1.8
Heart attack/myocardial infarction (self-reported)	1.1	1.4	6.1	2.5	1.5	0.9	1.2	-0.6	-1.1	0.0	-0.4	-1.7	-0.1	-0.3
Ulcerative Colitis (UC)	1.0	1.9	4.9	-1.4	-0.9	-1.4	1.1	2.2	1.0	-1.0	0.1	1.5	0.9	-2.2
Major Depression (MDD)	1.0	1.2	4.7	0.1	0.1	0.8	2.2	1.2	1.1	1.0	1.5	0.4	1.4	-0.1
Neuroticism (2016)	1.0	1.4	8.4	0.9	-0.6	-0.2	-0.4	-0.7	-2.9	1.0	-0.6	-1.6	-1.0	0.4
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.3	19.2	-4.4	-1.7	-0.7	-0.7	-1.3	0.0	0.1	0.8	0.5	-0.0	-0.3
Heart attack	1.0	1.3	4.5	2.1	1.4	0.6	1.2	-0.7	-1.0	-0.3	-0.7	-1.7	0.2	-0.8
Alcohol intake versus 10 years previously	1.0	1.5	4.7	-0.1	0.4	1.9	2.2	-0.5	1.4	0.5	1.0	-0.1	1.9	-0.7
Pulse wave Arterial Stiffness index	1.0	1.2	5.0	0.7	0.4	0.3	-1.1	-1.0	-0.3	0.1	-0.3	0.6	-2.2	2.1
Tense / ‘highly strung’	1.0	1.6	8.4	-1.2	-2.9	-0.5	0.5	-1.1	-1.8	0.3	-0.3	-0.7	-1.1	1.1
Health satisfaction	1.0	1.3	4.8	0.9	-1.0	-0.4	1.2	-0.2	0.3	-2.2	-1.1	-0.8	0.2	-2.2
Qualifications: College or University degree	1.0	3.0	9.7	-0.0	-0.9	-2.2	-1.1	0.6	-0.3	-2.6	-2.5	-1.6	0.7	-3.1
Overall health rating	1.0	2.2	8.9	3.0	0.8	0.5	2.7	-0.4	0.3	-1.3	-0.9	-1.1	0.7	-1.6
Illnesses of siblings: Diabetes	1.0	1.3	6.3	2.5	0.3	-0.8	1.3	1.1	0.2	-1.2	-0.3	-0.1	0.5	-1.4
Friendships satisfaction	1.0	1.3	5.0	2.2	-0.5	-1.6	0.0	1.4	-0.0	-1.1	0.2	-0.7	0.4	-1.5
Medication: Aspirin	1.0	1.2	5.6	2.3	0.9	-0.4	1.0	0.1	0.3	-2.4	-0.3	-0.3	-0.3	-0.8
Supplements: Fish oil (including cod liver oil)	1.0	1.3	7.3	-0.7	-2.7	-1.1	-1.1	1.1	-0.6	-0.3	-1.1	-1.2	-0.0	-0.6
Average weekly beer plus cider intake	1.0	1.4	4.0	-0.0	1.6	1.7	0.5	1.2	0.6	2.0	1.4	0.8	0.2	1.0
Risk taking	1.0	1.5	3.8	1.4	-1.8	-0.2	1.4	1.4	1.9	-0.6	0.8	1.1	1.1	-0.7
Fractured/broken bones in last 5 years	1.0	1.3	3.4	1.7	0.7	-0.9	-1.2	0.4	-1.0	-1.8	-1.3	-1.2	-0.9	-0.7
Fasting Glucose	0.9	1.1	4.8	-0.3	0.3	0.6	0.0	-1.2	-1.4	0.1	-1.5	-2.2	-0.9	0.3
Type 2 Diabetes (T2D) (2012)	0.9	1.0	3.4	1.2	-0.1	-0.1	-0.3	-0.4	-1.8	0.6	-1.4	-1.8	0.8	0.0
Waist Hip Ratio (WHR)	0.9	3.9	18.7	3.4	-1.4	-0.2	2.6	4.3	0.1	1.2	1.1	-1.0	0.4	0.6
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	3.8	0.4	-0.8	-0.5	0.6	0.8	1.3	-1.9	-1.3	0.2	0.2	-1.9
Vitamin and mineral supplements	0.9	1.2	3.4	0.3	1.2	1.4	0.7	0.4	1.0	0.8	1.9	1.7	-0.1	1.0
Taking other prescription medications	0.9	1.3	3.7	1.6	-0.8	0.5	1.3	0.0	1.9	-1.6	-1.1	0.3	0.6	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.1	16.2	-4.0	-1.5	-1.0	-0.2	-0.7	0.1	-0.5	1.0	0.4	0.5	-1.2
Hearing difficulty/problems with background noise	0.9	1.4	3.8	1.9	1.8	1.3	1.5	1.1	0.7	0.4	0.3	0.8	1.4	-0.5
Allergy	0.9	2.2	5.6	-2.4	2.1	1.1	-1.2	-1.4	-0.0	1.4	1.7	1.3	0.1	1.6
Number of live births	0.9	1.2	4.3	-2.1	0.2	1.2	0.9	0.3	0.9	0.8	1.6	1.6	0.3	0.3
Wheeze or whistling in the chest in last year	0.9	1.6	8.7	3.0	-0.8	-0.1	1.5	1.4	-1.2	-0.3	-0.7	-0.7	-1.4	0.1
Pulse wave peak to peak time	0.9	1.1	4.3	-0.5	-0.2	-0.5	0.9	1.1	-0.0	-0.3	0.1	-0.9	2.0	-2.1
Medication for pain relief, constipation, heartburn	0.9	1.5	4.4	-0.3	1.3	1.2	-1.3	0.5	0.3	2.1	2.1	0.8	0.5	1.5
Migraine (self-reported)	0.9	1.1	2.5	-0.4	-1.6	-0.7	0.7	1.3	1.2	0.1	1.1	1.6	0.6	-0.9
Mean time to correctly identify matches	0.9	1.7	4.2	0.0	-1.0	-1.5	-0.4	-0.8	0.7	-2.1	-2.0	-1.5	0.5	-1.9
Family relationship satisfaction	0.9	1.1	2.8	1.2	-0.6	-0.7	0.6	1.3	-0.1	-1.2	-0.7	-1.5	0.9	-1.7
Commuting to job workplace: Car/motor vehicle	0.9	1.1	4.0	-0.9	-2.0	-1.0	-0.1	0.1	0.1	-1.1	-1.3	-1.5	0.4	-0.8
Mood swings	0.9	1.6	5.5	0.6	-1.0	2.3	1.9	0.1	0.8	1.7	0.7	0.4	1.4	0.8
Medication for cholesterol	0.9	1.3	7.2	-1.2	-0.9	-1.2	-2.7	0.4	-0.4	-0.5	-0.2	-1.6	0.2	-0.8
Back pain experienced in last month	0.9	1.3	3.7	1.1	1.0	-0.5	0.3	-0.1	-1.1	-1.5	-1.9	-1.3	-1.3	-1.2
Wears glasses or contact lenses	0.9	1.0	8.1	-2.9	-0.0	-0.1	-0.3	0.1	0.3	-0.5	-0.6	0.4	0.7	-1.2
Medication: Paracetamol	0.9	1.4	6.9	-2.6	-0.5	1.3	1.2	-0.2	1.0	1.3	0.2	1.6	0.3	0.1
Cholesterol lowering medication	0.9	1.4	6.6	2.3	0.6	0.5	2.6	0.5	0.0	0.6	0.8	1.1	0.6	0.2
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	2.6	1.1	-1.2	-1.0	1.5	0.6	1.1	-1.6	-0.0	0.6	-0.0	-1.1
Body Mass Index (BMI) (2010)	0.8	1.0	2.5	1.6	1.4	0.1	0.6	-0.8	-0.7	-1.2	-1.4	-1.3	-0.2	-0.8
Mean Putamen Volume	0.8	0.9	4.2	1.3	2.1	0.8	0.3	0.2	1.3	-0.6	-0.1	-0.6	0.8	-0.7
BMI	0.8	4.5	9.3	2.2	1.9	-0.3	2.2	-3.0	-1.4	-3.0	-2.6	-2.3	-1.4	-1.4
Medication: Levothyroxine sodium	0.8	1.4	6.1	-1.4	-0.8	-0.0	-1.8	-2.5	-1.3	0.2	-1.0	-0.1	0.2	0.3
Had menopause	0.8	1.0	2.7	-0.1	1.6	-0.4	1.6	0.8	1.4	-0.6	-0.0	0.8	0.8	-1.3
Illnesses of siblings	0.8	1.1	2.7	-1.6	-1.1	0.5	-0.2	-1.2	-1.3	0.7	-0.7	-1.6	-0.5	0.8
Time employed in main current job	0.8	0.9	2.3	-1.4	-0.7	1.3	0.6	-0.7	1.5	0.6	0.3	1.2	0.2	0.9
Father’s age at death	0.8	1.1	3.9	-1.2	-0.3	0.3	-2.0	-1.4	-0.9	0.1	-0.6	-0.6	-1.2	1.2
Worrier / anxious feelings	0.8	1.6	7.8	0.1	-0.4	-0.1	-0.1	-2.8	-2.1	0.9	-0.4	-1.1	-1.1	1.1
Happiness	0.8	1.0	2.8	0.2	-0.4	-0.8	1.7	0.9	-0.2	-0.0	-0.4	-1.2	1.6	-1.4
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	3.5	1.9	-0.4	1.1	1.2	1.5	-0.0	0.3	-0.6	-0.1	0.8	-0.2
Illnesses of mother	0.8	1.0	3.6	-1.4	0.1	0.9	-1.0	0.5	0.2	1.9	0.8	-0.4	0.2	1.7
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	3.6	-1.9	-1.4	0.2	-1.2	0.3	-0.5	1.2	1.3	0.9	-0.9	1.3
Glaucoma (self-reported)	0.8	1.0	3.6	1.1	0.2	-0.8	0.5	0.5	-0.0	-1.1	-1.9	-1.2	0.7	-1.3
Neck or shoulder pain in last month	0.8	1.2	3.8	-0.3	-0.7	-1.3	-0.3	-0.0	0.3	-1.7	-1.7	-0.9	0.1	-2.0
Leg pain on walking	0.8	1.0	4.5	-0.6	-2.1	-0.8	1.2	-1.4	0.5	-1.2	-0.5	0.2	-0.3	-0.5
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	5.5	-1.5	0.1	-0.0	-0.7	0.0	0.5	1.2	2.3	0.4	0.1	0.9
Pain type(s) experienced in last month: Hip pain	0.8	1.0	3.9	-0.3	2.0	1.7	-1.2	-0.6	0.3	-0.2	-1.0	-1.1	-0.4	0.3
Depression (Nagel 2018)	0.7	1.1	4.4	0.7	-1.0	0.7	2.1	1.0	0.9	0.8	0.8	0.5	1.5	0.0
Neuroticism (Nagel 2018)	0.7	1.7	5.6	0.6	-1.2	1.5	2.0	0.1	0.2	2.4	1.2	0.9	0.6	1.5
HbA1C	0.7	0.7	2.3	-1.2	0.6	-0.6	-1.1	-0.6	-0.4	-1.5	-0.1	0.1	-1.1	-0.8
Cardiovascular Disease	0.7	2.4	9.6	3.1	0.9	-0.1	2.7	-1.7	1.2	-1.4	-0.6	-0.3	1.0	-1.2
Hand grip strength (left)	0.7	1.8	4.9	-0.1	-1.0	1.1	-1.7	0.6	-2.0	2.2	0.5	-1.0	-0.5	1.9
Average weekly spirits intake	0.7	0.9	4.1	-0.1	0.2	2.0	0.8	-1.4	-0.1	0.3	0.1	0.2	-0.6	1.5
Hearing difficulty/problems: Yes	0.7	1.0	4.6	1.4	1.9	2.1	0.1	1.0	-0.2	-0.1	-0.1	0.5	0.1	-0.2
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	1.7	0.9	1.2	-0.8	1.3	0.3	1.0	-0.9	0.6	0.6	-0.4	-1.2
Trunk fat percentage	0.7	2.7	5.7	1.8	2.2	-0.3	1.4	-2.3	-1.0	-2.4	-1.6	-1.0	-1.9	-0.5
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	3.1	0.0	0.1	0.2	0.4	0.5	-0.2	-1.6	-1.3	-0.7	0.3	-1.8
Trunk fat mass	0.7	3.0	6.9	2.3	2.6	-0.2	1.6	-1.8	-1.3	-2.3	-1.8	-1.5	-1.5	-0.8
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.0	3.1	1.4	-1.4	0.1	1.8	1.1	0.5	1.0	0.2	0.9	0.8	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	3.6	1.2	0.1	1.9	0.9	-0.0	0.1	1.8	0.8	0.5	0.9	1.3
Pulse rate	0.7	1.1	3.8	-0.3	-0.1	-0.3	-1.9	-1.4	-0.1	0.1	-0.1	0.4	-1.7	1.9
Medication: Cholesterol lowering	0.7	1.0	2.7	0.8	1.2	-0.5	0.9	-0.9	-0.5	-0.8	-1.6	-1.6	0.3	-1.1
Body fat percentage	0.7	2.6	6.1	1.8	2.0	-0.4	1.7	-2.2	-0.9	-2.5	-1.6	-0.9	-1.7	-0.6
Number of children fathered	0.7	0.8	2.2	-1.3	0.8	1.4	0.0	-0.5	-0.2	0.8	-0.9	0.5	-0.8	1.5
Suffer from ‘nerves’	0.7	1.1	6.4	0.5	-2.5	-0.8	0.9	-0.9	-0.5	-0.6	-1.1	-0.7	0.3	-0.6
Average weekly red wine intake	0.7	1.1	5.3	-0.1	-0.9	-2.3	-1.4	1.3	-0.5	-1.1	0.1	-0.3	-0.9	-0.0
Diabetes diagnosed by doctor	0.7	1.1	3.3	1.3	1.2	-0.8	1.8	-0.2	0.2	-1.4	-0.8	-0.5	0.2	-1.6
Breast cancer (self-reported)	0.7	0.8	4.0	-2.0	0.4	1.0	0.3	-0.6	1.1	0.4	0.3	1.1	0.3	0.6
Miserableness	0.7	1.2	4.5	0.7	-0.2	1.3	1.1	0.7	-0.4	2.1	1.0	0.3	0.4	1.6
Guilty feelings	0.7	1.0	4.5	2.1	-0.6	-0.3	1.6	0.8	-1.1	1.2	0.4	0.4	0.1	0.3
Commuting to job workplace: Public transport	0.7	0.8	3.2	0.9	0.3	-0.5	-0.3	1.8	-0.4	-0.4	-0.7	-0.7	0.8	-1.6
Medication: Bendroflumethiazide	0.7	1.1	3.8	1.2	-0.1	0.6	1.9	-0.0	1.1	0.1	0.3	1.3	1.7	-0.6
Illnesses of father: High blood pressure	0.7	0.9	4.2	0.3	1.1	-0.4	-2.1	-0.7	-0.7	-0.6	-1.2	-1.0	0.1	-0.6
Ever had prostate specific antigen (PSA) test	0.7	0.8	2.5	-0.3	0.2	1.6	1.3	-0.6	1.2	0.2	0.6	1.2	1.0	0.2
Ever depressed for a whole week	0.7	0.9	2.5	-0.0	-0.9	-0.2	1.5	0.7	1.6	0.5	0.6	0.9	1.2	-0.7
Unable to work because of sickness or disability	0.7	0.9	3.1	1.8	0.7	0.8	1.4	-0.4	1.3	-0.5	0.4	1.2	0.6	-0.1
Myopia	0.7	1.0	2.9	-0.7	0.0	-1.1	-1.7	-1.2	-1.4	-0.3	-0.2	0.0	-1.7	0.5
Bipolar Disorder (2018)	0.6	1.0	1.8	1.0	-1.1	-1.1	0.8	1.2	1.3	-1.3	0.8	0.6	-0.4	-1.0
Intelligence (Savage-Jansen 2018)	0.6	1.8	7.6	1.0	0.4	-0.8	-2.8	1.0	-2.5	0.1	-0.6	-0.6	-1.1	1.1
Lupus	0.6	1.0	3.7	0.3	1.9	-0.2	-0.4	-0.7	0.3	-1.3	-1.0	-1.3	-1.2	-0.7
Blood Eosinophil Count	0.6	4.6	13.4	1.0	0.4	3.3	-1.7	-2.8	-1.8	2.2	-0.0	-2.5	-0.4	3.7
Blood Red Count	0.6	6.0	23.4	4.8	4.2	0.0	2.8	1.3	1.4	-2.1	1.5	1.9	-0.3	-1.9
Sensitivity / hurt feelings	0.6	1.0	6.2	-1.4	-0.4	-0.6	-0.2	-2.5	-1.1	0.0	-0.5	0.5	-0.5	0.5
Angina	0.6	0.8	4.7	1.2	0.4	-0.1	0.2	-2.2	-0.6	-0.9	-0.6	-0.5	0.2	-0.3
Medication: Metformin	0.6	0.8	5.0	0.8	2.2	0.7	1.2	-0.2	0.6	0.3	0.6	0.9	-0.0	-0.0
Diabetes (mother)	0.6	0.8	2.9	-0.7	1.7	1.7	0.9	-1.2	0.2	0.3	-0.3	-0.3	-0.3	0.5
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.4	0.3	1.1	1.6	0.9	0.0	1.0	0.7	0.6	0.8	-0.1	0.8
Qualifications: CSEs or equivalent	0.6	0.8	2.9	-0.2	0.0	0.7	-1.7	-0.6	-0.6	0.9	0.6	0.8	-1.0	1.2
Nervous feelings	0.6	1.2	6.0	-0.4	-2.4	0.5	-0.3	-0.6	-1.4	1.6	-0.2	-1.0	0.0	0.9
Hair/balding pattern: Pattern 2	0.6	0.7	1.8	-0.8	0.4	1.3	0.7	1.0	0.4	1.1	1.4	0.2	0.6	0.4
Forced vital capacity (FVC)	0.6	2.3	4.9	-1.5	-1.6	-1.5	-1.8	1.0	-1.2	-1.4	-2.0	-1.5	0.5	-2.2
Mouth/teeth dental problems	0.6	0.9	2.6	-1.2	-0.7	0.5	-1.0	0.0	-1.6	1.4	0.6	-0.3	-0.7	1.2
Neuroticism score	0.6	1.2	3.6	0.5	-0.7	1.4	1.9	-1.2	-0.8	1.6	-0.2	-0.4	0.6	1.0
Arm fat percentage (right)	0.6	2.2	6.4	1.3	1.8	-0.3	2.1	-2.5	-0.6	-2.0	-1.3	-0.7	-1.4	-0.3
Mouth/teeth dental problems: Dentures	0.6	1.0	5.0	-0.2	-0.2	0.2	2.2	-0.2	0.6	-1.0	-1.2	-0.3	1.3	-1.1
Depression (self-reported)	0.6	0.8	2.8	0.4	-1.3	0.0	-0.3	-0.9	-1.5	-0.1	-0.2	-0.0	-1.7	0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	5.3	-2.3	-1.6	-0.9	-1.2	-0.3	-0.8	-0.9	-1.5	-0.9	1.3	-1.8
Arm fat mass (right)	0.6	2.4	5.6	1.9	2.4	-0.0	1.8	-1.7	-1.4	-1.7	-1.4	-1.4	-1.2	-0.4
Medication: Paracetamol	0.6	1.0	6.7	-2.6	-0.8	0.4	1.0	-0.3	0.7	0.3	-0.5	1.0	0.0	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	4.0	2.0	-0.8	-0.7	0.4	0.6	-0.6	-1.1	-0.1	-0.8	-0.8	-0.8
Whole body fat mass	0.6	2.6	5.9	2.2	2.4	-0.2	1.8	-1.8	-1.2	-2.1	-1.5	-1.3	-1.3	-0.7
Arm fat percentage (left)	0.6	2.6	8.3	1.2	1.8	-0.4	2.0	-2.9	-0.5	-2.5	-1.4	-0.6	-1.4	-0.6
Loneliness, isolation	0.6	0.9	3.3	0.9	-0.3	0.8	0.9	-0.9	-0.2	1.4	0.9	0.4	-0.5	1.8
Long-standing illness, disability or infirmity	0.6	0.9	3.1	1.1	-0.0	-0.2	0.8	-1.4	0.4	-1.6	-1.8	0.0	0.0	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	5.3	2.3	0.2	0.7	0.7	1.2	0.7	-0.4	-0.6	-0.0	1.3	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	5.9	-2.4	-1.9	-1.1	-1.4	-0.2	-0.6	-0.9	-0.6	0.4	0.1	-0.3
Arm fat mass (left)	0.6	2.5	5.5	1.7	2.3	-0.3	1.7	-2.1	-1.3	-2.0	-1.5	-1.2	-1.4	-0.6
High cholesterol (Self-reported)	0.6	1.0	6.5	2.5	0.5	-0.1	1.7	0.4	-0.5	0.7	0.1	-0.1	0.1	0.4
Medication: Lisinopril	0.6	0.7	5.1	1.5	-0.5	-0.2	2.3	-0.1	0.2	0.1	-0.3	0.5	0.1	-0.4
Supplements: Calcium	0.6	0.7	4.2	0.1	2.0	0.0	-0.7	0.0	-0.4	-1.1	-0.6	0.2	-0.6	-0.8
Basal cell carcinoma (self-reported)	0.6	0.7	2.6	-0.2	0.4	1.1	-0.6	0.9	1.1	1.1	1.6	0.0	0.5	0.4
Schizophrenia (2018)	0.5	0.9	3.1	0.2	-0.3	1.3	1.7	0.3	0.3	1.4	0.9	0.8	1.1	0.6
Worry (Nagel 2018)	0.5	1.1	4.0	-0.0	-2.0	0.8	1.3	-0.5	-0.7	1.9	0.3	-0.1	-0.0	1.4
Ovarian Cancer	0.5	0.7	2.2	-1.5	-0.4	-0.4	-0.9	-1.3	0.7	-0.5	-0.3	-0.5	1.2	-0.8
Prostate Cancer	0.5	0.7	2.1	0.1	1.4	0.3	-0.7	-1.3	0.1	-0.4	-0.8	-0.9	-1.4	0.1
Blood Platelet Count	0.5	5.6	15.9	-2.3	4.0	3.0	0.8	-1.7	1.1	3.3	2.6	1.7	1.0	2.2
Systolic Blood Pressure	0.5	2.3	10.6	3.3	2.9	1.0	0.3	-1.1	-1.4	-0.1	-0.5	-1.0	-0.4	0.6
Respiratory disease	0.5	1.1	3.9	1.2	-0.7	-0.3	0.6	0.7	-0.5	-2.0	-1.3	-0.9	-0.3	-1.5
Neuroticism	0.5	1.3	6.8	1.0	-1.2	0.9	2.6	-0.1	-0.5	1.8	0.1	0.1	0.2	0.9
Medication: Co-codamol	0.5	0.6	2.3	0.3	-0.4	0.2	0.2	0.8	-0.2	0.2	0.8	1.5	-0.8	1.2
Severe depression (siblings)	0.5	0.5	1.4	-0.7	0.8	-0.5	0.5	-1.2	0.3	-1.1	-0.4	-0.2	-0.1	-1.2
Chronic bronchitis/emphysema (father)	0.5	0.6	1.8	0.3	-1.1	-0.1	0.2	-0.8	-1.2	-1.1	-1.4	-0.0	-0.2	-0.8
Body mass index (BMI)	0.5	2.2	6.3	1.4	2.5	0.2	1.8	-2.2	-1.0	-1.7	-1.3	-0.9	-1.1	-0.6
Waist circumference	0.5	1.9	7.3	2.7	1.8	-0.1	2.5	-0.0	-1.1	-1.0	-0.7	-1.2	-0.6	-0.3
Alcohol usually taken with meals	0.5	0.8	3.3	-0.6	-1.7	-0.0	0.4	0.6	1.8	0.2	0.1	0.1	1.2	-0.7
Pain all over the body in last month	0.5	0.5	1.3	1.1	-0.9	-1.2	0.4	-0.4	-1.2	-0.4	-0.2	-0.4	-0.7	0.2
Weight	0.5	2.6	7.0	2.5	2.6	0.1	1.3	-1.1	-1.9	-1.4	-1.4	-1.6	-1.2	-0.6
Hip circumference	0.5	2.1	5.0	1.1	1.9	-0.3	1.0	-2.2	-2.0	-1.3	-1.7	-1.1	-1.3	-0.5
Prospective memory result	0.5	0.6	1.7	-1.1	-1.3	0.4	1.1	-1.0	0.5	0.8	0.3	0.8	-0.1	0.1
Qualifications: O levels/GCSEs or equivalent	0.5	0.7	3.4	-0.3	-0.0	-0.1	0.3	0.2	1.1	0.9	1.6	1.8	0.1	0.2
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	1.9	-0.2	0.5	0.1	-0.9	-0.4	1.3	-0.7	0.1	1.4	-1.0	0.4
Headache pain in last month	0.5	0.9	4.6	-1.0	-0.7	0.3	-0.8	-2.1	0.8	-0.4	-0.9	0.3	0.8	-0.4
Leg fat percentage (right)	0.5	1.7	4.2	1.5	1.8	0.2	2.0	-1.9	-0.7	-1.4	-0.5	0.1	-1.5	0.4
Arm fat-free mass (right)	0.5	2.5	6.0	2.5	2.1	-0.3	0.4	0.8	-2.3	-1.1	-1.5	-2.3	-0.3	-1.5
Angina (self-reported)	0.5	0.7	3.8	1.2	0.6	-0.2	0.1	-2.0	-0.7	-1.1	-0.5	-0.5	0.2	-0.4
Leg fat mass (right)	0.5	1.9	5.5	2.0	2.3	0.1	1.9	-1.4	-0.7	-1.7	-0.7	-0.5	-1.2	-0.3
Arm predicted mass (right)	0.5	2.6	6.1	2.5	2.3	-0.1	0.0	0.4	-2.4	-1.0	-1.5	-2.5	-0.5	-1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	4.3	0.3	1.0	0.6	-2.0	0.2	-2.1	0.9	-0.1	-1.1	0.1	0.7
Alcohol drinker status: Never	0.5	0.6	1.9	1.2	-0.9	-0.7	-0.2	-0.3	-0.4	-1.4	-0.4	-1.3	-0.2	-0.6
Arm fat-free mass (left)	0.5	2.6	7.1	2.7	2.4	0.1	0.4	0.5	-2.4	-0.5	-1.4	-2.5	-0.3	-0.9
Pain experienced in last month	0.5	0.8	3.5	-0.2	-0.2	0.5	0.3	0.8	0.5	1.2	1.9	1.3	0.6	0.8
Alcohol drinker status: Previous	0.5	0.6	1.9	0.7	-1.4	-1.2	0.2	0.8	-0.8	0.1	-0.6	0.6	-0.6	0.3
Leg fat mass (left)	0.5	2.0	6.0	2.0	2.5	0.1	1.9	-1.5	-0.5	-1.9	-0.8	-0.7	-0.8	-0.7
Arm predicted mass (left)	0.5	2.8	7.8	2.8	2.4	-0.1	0.4	0.6	-2.5	-0.6	-1.5	-2.6	-0.3	-1.1
Bipolar Disorder or Schizophrenia	0.4	0.9	3.6	0.8	-0.9	0.3	1.9	1.0	1.1	0.3	1.2	1.0	0.6	-0.1
Schizophrenia vs Biploar Disorder	0.4	0.5	1.6	-1.3	0.9	0.8	-0.1	-0.6	0.3	0.6	0.4	-0.1	1.0	0.1
Alzheimer’s Disease (including proxy)	0.4	0.6	2.5	0.6	1.0	0.8	-0.4	-0.4	-1.6	-0.2	-0.3	-0.1	-1.1	0.5
Breast Cancer	0.4	0.9	4.5	2.1	-0.4	-0.3	-0.3	-0.4	-1.5	-0.6	-0.9	-1.2	0.6	-0.4
Age at First Birth	0.4	0.5	2.1	-0.8	-0.4	-0.0	-0.2	0.5	0.7	0.9	1.2	0.2	-0.1	1.4
Rheumatoid Arthritis	0.4	0.6	1.1	0.3	-1.0	-1.0	-0.2	0.6	-0.8	-0.9	-0.9	-0.3	-1.1	-0.4
Triglycerides	0.4	0.7	2.4	1.0	-0.5	0.1	1.6	0.3	1.2	-0.8	0.6	0.9	0.3	-0.4
Ever had hysterectomy (womb removed)	0.4	0.4	3.1	-0.2	-0.2	0.9	1.8	0.5	0.0	0.3	-0.2	0.7	-0.1	-0.1
Systolic blood pressure, automated reading	0.4	1.2	7.3	1.3	2.7	1.2	1.2	-0.3	-0.2	-0.0	0.6	0.1	-0.7	0.4
Diabetes (father)	0.4	0.5	1.4	1.2	0.4	0.4	0.8	0.8	-0.5	0.7	-0.2	-0.8	0.5	-0.7
Leg fat-free mass (left)	0.4	2.2	5.8	2.0	2.4	-0.3	0.2	-0.9	-2.1	-1.2	-1.4	-2.0	-0.9	-0.6
Hand grip strength (right)	0.4	1.1	3.5	0.2	-0.6	1.1	-1.1	0.3	-1.2	1.9	0.6	-0.7	-0.7	1.7
Relative age voice broke	0.4	0.6	1.6	0.5	0.7	0.8	-0.7	0.5	-1.1	0.4	-1.0	-0.5	-1.3	0.9
Serious illness, injury or assault to yourself	0.4	0.5	1.7	0.6	-0.9	0.4	-0.0	0.7	-0.1	0.2	0.0	0.9	-1.3	1.0
Leg predicted mass (left)	0.4	2.1	5.8	1.9	2.4	-0.3	0.3	-1.0	-2.0	-1.2	-1.3	-2.0	-0.9	-0.6
Number of incorrect matches in round	0.4	0.7	2.7	1.6	-0.6	-0.8	-0.2	0.3	-1.0	0.0	-1.1	-0.4	-1.2	0.3
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.7	0.7	0.3	-0.8	-0.6	-0.8	0.5	-1.2	-1.3	-0.1	-0.1	-0.4
Medication: Ramipril	0.4	0.6	2.7	-0.3	0.9	-1.0	-0.1	-1.6	-0.1	-0.6	0.4	0.5	-0.8	0.2
Fluid intelligence score	0.4	0.8	4.5	-0.2	-0.2	-0.8	-2.1	0.1	-1.4	0.5	0.4	0.1	-0.2	1.2
Lung cancer (father)	0.4	0.5	1.1	-0.8	0.7	0.9	0.8	-0.3	0.6	0.9	-0.7	-0.4	1.0	0.2
Exposure to tobacco smoke at home	0.4	0.5	1.8	-0.2	-0.1	0.3	1.0	-0.6	1.1	0.1	-0.4	1.4	0.5	-0.7
Gout (self-reported)	0.4	0.5	3.6	0.9	-0.8	0.3	1.9	0.7	0.1	0.1	0.1	0.1	-0.1	0.2
High blood pressure (siblings)	0.4	0.5	3.2	0.8	-0.0	-0.4	-0.7	0.4	0.7	-0.5	0.3	1.8	-0.2	0.2
Comparative body size at age 10	0.4	1.0	2.5	-1.5	-0.7	-0.7	0.9	-1.0	-0.6	-1.2	-1.6	-0.7	-1.0	-0.7
Number of full brothers	0.4	0.4	1.6	0.1	-0.2	-0.6	-0.8	0.3	-0.3	-0.7	-0.3	-1.1	0.5	-1.3
Age at first live birth	0.4	0.7	3.2	-0.7	0.3	-0.2	-1.8	0.2	-0.2	0.8	1.1	0.1	-0.3	1.5
Emphysema/chronic bronchitis	0.4	0.4	2.8	0.4	0.0	-0.0	-0.0	-0.8	-0.7	-0.4	-0.1	-0.7	-1.7	0.1
Number of full sisters	0.4	0.5	2.3	1.1	0.5	-0.1	0.4	1.5	-0.3	0.7	0.8	-0.1	0.8	-0.3
Age at last live birth	0.4	0.6	3.0	-0.7	0.4	-0.2	-0.4	1.0	0.7	0.9	1.7	0.4	0.7	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.8	0.7	0.9	0.5	0.9	0.2	-0.6	1.4	0.4	-0.3	-0.2	0.7
Whole body fat-free mass	0.4	2.1	5.4	2.3	2.3	-0.1	0.6	0.3	-2.1	-0.7	-1.2	-2.2	-0.2	-1.0
Leg fat-free mass (right)	0.4	2.1	5.7	2.2	2.4	-0.2	0.5	-0.7	-1.8	-1.1	-1.3	-2.1	-0.5	-1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.4	1.8	1.3	-0.4	0.3	-0.1	0.2	0.1	-0.6	-1.3	-0.6	-0.1	0.3
Asthma (self-reported)	0.4	0.7	2.9	1.7	-0.2	0.0	0.1	0.9	0.7	-1.5	-0.5	0.3	0.1	-1.2
Whole body water mass	0.4	2.2	5.6	2.4	2.2	-0.1	0.3	0.3	-2.3	-0.7	-1.3	-2.4	-0.4	-0.9
Leg predicted mass (right)	0.4	2.1	6.2	2.1	2.5	-0.2	0.4	-0.8	-1.9	-1.2	-1.3	-2.1	-0.5	-1.0
Medication: Blood pressure	0.4	0.8	4.3	2.1	0.0	-0.0	1.7	0.3	-0.2	-0.4	-0.1	0.8	-0.1	0.3
Basal metabolic rate	0.4	2.4	6.1	2.5	2.4	-0.1	0.6	-0.1	-2.2	-0.9	-1.4	-2.3	-0.5	-0.9
Leg fat percentage (left)	0.4	1.6	4.9	1.6	1.9	0.3	2.2	-1.8	-0.3	-1.5	-0.5	0.0	-0.9	-0.1
Age started oral contraceptive pill	0.4	0.5	2.4	-0.1	1.5	-0.5	0.0	0.9	-0.4	-0.2	-0.0	0.7	-1.1	0.3
Diastolic blood pressure, automated reading	0.4	1.2	4.5	2.1	1.6	-0.5	0.6	-1.0	-0.2	-1.4	-0.8	-1.0	-0.5	-0.7
Commuting to job workplace: Cycle	0.4	0.5	2.9	0.5	-0.5	-0.9	-0.0	0.0	-0.6	-0.3	-1.7	-0.2	0.0	-0.7
Alzheimer’s Disease (in mother)	0.3	0.3	0.9	-0.4	0.7	0.6	0.6	-0.6	-1.0	0.2	0.5	0.3	-0.6	0.2
Verbal and Numeric Reasoning (VNR)	0.3	0.8	3.4	-0.6	-0.2	-0.2	-1.9	-0.4	-1.3	0.6	0.6	-0.4	-0.2	1.4
Coronary Artery Disease (CAD)	0.3	0.3	1.0	-0.4	-0.4	0.3	0.9	-1.0	0.4	-0.5	0.2	0.8	-0.1	0.2
HDL Cholesterol	0.3	0.5	1.6	-0.3	-0.3	0.0	-0.2	0.9	-0.9	1.2	0.6	0.2	-0.7	0.9
Ulcerative Colitis	0.3	0.4	1.3	-1.1	-0.9	-0.9	0.4	0.7	0.1	-0.4	-0.1	0.0	0.3	-0.7
Lung FEV1/FVC ratio	0.3	1.6	5.2	-1.4	-0.6	-1.2	-0.8	-2.0	-2.3	-0.1	-1.4	-1.4	-0.2	-0.3
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.4	0.4	-0.8	0.4	1.2	-0.5	0.1	0.7	0.5	0.3	0.9	0.6
Medication for hormone replacement therapy	0.3	0.3	1.4	-1.0	0.1	0.3	0.3	-0.4	0.3	0.1	-0.6	1.2	-0.6	0.2
Impedance of leg (right)	0.3	1.4	5.1	-0.5	-2.3	-0.1	-1.3	1.2	0.1	1.2	1.0	0.9	-0.7	1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.5	1.2	1.1	0.5	0.4	1.0	1.1	-0.1	0.7	0.3	-0.4	0.7	-0.1
Supplements: Glucosamine	0.3	0.4	1.9	0.0	-0.2	-0.7	0.2	1.4	1.0	0.8	0.2	-0.4	0.8	0.1
Medication: Atenolol	0.3	0.4	1.2	0.8	-0.4	0.8	0.5	0.5	0.7	0.2	0.2	0.8	1.1	0.2
Sitting height	0.3	1.8	7.1	2.2	2.7	-0.3	-0.5	-0.3	-1.7	-0.9	-0.6	-1.5	-1.0	-0.8
Trunk fat-free mass	0.3	2.0	5.2	2.3	2.2	0.4	0.6	0.9	-2.1	-0.0	-1.0	-2.1	0.0	-0.7
Trunk predicted mass	0.3	1.9	5.3	2.3	2.1	0.4	0.5	1.1	-2.1	0.1	-0.8	-2.0	0.1	-0.6
Blood clot in the leg (DVT)	0.3	0.4	0.9	0.9	-0.9	0.1	0.1	1.0	-0.7	0.5	-0.7	-0.5	-0.2	-0.6
Forced vital capacity (FVC), Best measure	0.3	1.0	2.2	-1.5	-1.4	-0.7	-1.1	0.5	-0.8	-0.6	-1.1	-0.6	1.0	-1.4
Worry too long after embarrassment	0.3	0.5	2.0	0.6	-1.4	0.5	0.7	-1.2	-0.1	0.6	-0.1	-0.5	0.5	0.3
Shortness of breath walking on level ground	0.3	0.3	1.1	-0.1	0.6	0.2	1.0	-0.5	0.2	-1.0	-0.6	0.3	0.1	-0.2
Mouth/teeth dental problems: Loose teeth	0.3	0.3	1.0	0.3	-0.9	-0.5	0.9	0.7	1.0	-0.2	-0.4	-0.1	-0.2	0.3
Medication: Seretide 50 evohaler	0.3	0.3	0.9	1.0	-0.7	-0.6	0.4	0.2	0.6	-0.6	0.1	0.5	-0.4	-0.7
Pulse rate, automated reading	0.3	1.0	5.2	0.3	2.3	0.5	0.3	-1.1	0.4	0.3	0.6	1.4	-1.0	0.6
Alcohol intake frequency.	0.3	0.8	2.1	0.1	-0.9	-1.1	0.8	-1.4	-0.4	-1.3	-0.4	-0.4	0.1	-1.1
Comparative height size at age 10	0.3	1.7	7.5	2.4	0.1	-1.3	0.5	2.7	-1.4	-0.1	0.3	-1.0	0.2	-0.8
Qualifications: nursing, teaching	0.3	0.5	1.7	1.1	0.5	-1.1	0.2	0.1	-0.5	-1.0	-0.3	0.2	-1.3	-0.5
Eye problems/disorders: Cataract	0.3	0.4	1.2	0.7	0.5	0.3	0.0	1.0	1.0	-0.2	0.4	1.1	0.4	-0.1
Hearing aid user	0.3	0.3	1.5	0.0	0.1	0.9	0.2	-0.3	-0.5	0.1	-0.1	1.2	-0.6	0.6
Tinnitus: Yes, now most or all of the time	0.3	0.4	1.1	0.5	-1.1	-0.1	0.7	0.5	-0.5	-0.3	-1.0	-0.6	0.3	-0.6
Irritability	0.3	0.4	1.0	0.6	-0.3	0.4	1.0	0.7	-0.6	0.8	0.7	1.0	-0.5	0.5
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.0	1.0	-0.7	0.0	-0.2	0.9	-1.0	0.5	-0.6	-0.7	-0.2	-0.5
Schizophrenia (2014)	0.2	0.4	2.2	0.1	-0.3	0.5	1.5	0.0	0.1	0.7	0.8	0.2	0.8	0.5
Height	0.2	3.5	7.8	2.5	2.6	2.3	0.4	2.8	-0.6	2.7	1.2	0.8	0.8	1.2
Lung FVC	0.2	1.0	6.0	-2.4	-1.4	0.4	-1.6	-0.1	0.0	-0.3	-0.5	-0.2	0.0	-0.0
Relative age of first facial hair	0.2	0.5	1.6	0.4	0.4	1.2	0.1	0.9	0.2	1.3	-0.3	0.1	-0.4	1.0
Maternal smoking around birth	0.2	0.4	1.0	0.7	1.0	0.8	0.8	0.3	-0.5	0.5	-0.3	-0.1	0.4	-0.5
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.7	0.3	-0.3	-0.1	0.8	-0.8	0.2	0.5	-0.7	-0.2	-0.2	-0.6
Impedance of leg (left)	0.2	1.1	4.7	-0.3	-2.2	-0.0	-0.8	1.4	0.5	1.2	1.1	0.9	0.0	1.1
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.8	0.3	0.4	-0.6	-0.7	-0.3	-0.4	0.7	0.7	0.0	-0.1	0.9
Qualifications: None of the above	0.2	0.5	1.2	0.6	-0.9	0.9	0.9	-0.7	-0.3	-0.1	-0.9	0.2	-0.2	1.1
Medication: Simvastatin	0.2	0.4	2.2	0.4	0.4	0.0	1.5	-0.8	0.2	-0.4	-0.1	0.1	-0.4	-0.3
Impedance of arm (right)	0.2	0.8	4.5	-0.4	-2.1	-0.5	-0.5	-0.3	0.6	0.5	0.2	0.8	-0.7	1.3
Asthma	0.2	0.5	2.3	1.5	0.1	0.3	0.0	0.7	0.5	-1.1	-0.3	0.4	0.1	-0.9
Impedance of arm (left)	0.2	1.1	5.2	-0.8	-2.3	-0.8	-1.0	-1.0	0.6	-0.2	-0.1	0.8	-1.0	1.0
Standing height	0.2	1.8	6.3	2.5	0.7	-0.3	-0.8	2.3	-2.0	0.5	-0.4	-1.6	-0.2	-0.2
Pulse wave reflection index	0.2	0.2	0.6	0.7	0.5	0.4	-0.8	0.2	-0.2	-0.2	-0.3	-0.6	-0.7	0.4
Birth weight	0.2	0.4	1.1	-0.8	0.2	0.1	0.8	-0.6	-0.9	1.1	0.2	-0.1	-0.4	1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	1.3	-1.1	0.8	0.6	0.3	-0.5	0.1	0.1	-0.3	-0.0	0.4	0.1
Impedance of whole body	0.2	0.9	5.7	-0.5	-2.4	-0.8	-1.1	0.3	0.5	0.2	0.2	0.8	-0.7	1.0
LDL Cholesterol	0.1	0.2	0.8	0.1	0.6	0.0	-0.5	-0.3	-0.5	-0.1	-0.3	-0.1	-0.9	0.4
Tanning	0.1	0.6	1.8	-0.5	-1.4	1.1	-0.3	1.1	-0.2	0.3	-0.9	-0.3	1.1	-0.1
Qualifications: A levels/AS levels or equivalent	0.1	0.3	1.1	0.6	-0.3	-0.5	-0.1	0.7	-0.5	0.1	-0.7	-1.1	0.1	-0.1
Knee pain experienced in last month	0.1	0.2	0.7	0.5	-0.2	0.8	0.1	0.5	-0.1	0.7	-0.2	0.3	0.2	0.5
Hair Pigment	0.0	1.1	2.0	-0.0	-1.2	1.4	1.1	1.1	1.0	1.2	1.0	1.2	-0.3	1.2

Hub : Genes

ITGA4

Models

Trait associations