[Hub]/) : Traits : Heel T-Score :

chr2:190,521,054-192,594,975

Best TWAS P=2.4e-15 · Best GWAS P=1.04e-14 conditioned to 0.776

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NAB1 0.06 0.06 lasso 2 0.04 4.3e-06 -7.16 7.5 4.7e-14 -0.74 0.21 0.79 FALSE
2 GTEx Adipose Visceral Omentum NAB1 0.15 0.00 lasso 3 0.00 2.5e-01 -7.52 -7.9 2.4e-15 0.84 0.03 0.58 TRUE
3 GTEx Artery Aorta AC005540.3 0.18 0.12 enet 22 0.18 2.9e-10 4.45 5.8 7.9e-09 -0.41 0.81 0.11 FALSE
4 GTEx Artery Tibial MFSD6 0.26 0.12 enet 25 0.22 3.2e-17 0.29 5.8 7.7e-09 -0.16 1.00 0.00 TRUE
5 GTEx Artery Tibial AC067945.4 0.09 0.02 lasso 4 0.02 7.2e-03 -6.09 6.7 2.5e-11 -0.58 0.13 0.23 FALSE
6 GTEx Artery Tibial AC005540.3 0.10 0.09 lasso 4 0.08 7.4e-07 -4.59 6.3 3.2e-10 -0.63 0.47 0.47 FALSE
7 GTEx Breast Mammary Tissue (Female) INPP1 0.16 0.02 lasso 4 0.03 5.2e-02 -5.60 6.7 1.9e-11 -0.65 0.04 0.42 FALSE
8 GTEx Esophagus Mucosa GLS 0.07 0.01 lasso 6 0.01 5.4e-02 -6.73 -6.6 4.5e-11 0.77 0.10 0.15 FALSE
9 GTEx Muscle Skeletal GLS 0.09 0.06 enet 21 0.05 1.0e-05 -4.59 -5.3 1.2e-07 0.47 0.96 0.04 FALSE
10 GTEx Testis NAB1 0.14 0.06 enet 20 0.10 5.1e-05 -6.49 -6.7 2.3e-11 0.78 0.08 0.90 FALSE
11 GTEx Testis AC067945.4 0.20 0.15 enet 16 0.15 4.6e-07 -3.71 5.3 1.4e-07 -0.53 0.72 0.24 FALSE
12 GTEx Thyroid AC005540.3 0.09 0.07 enet 5 0.04 2.5e-04 -4.59 6.0 1.9e-09 -0.60 0.20 0.75 FALSE
13 YFS Blood GLS 0.08 0.08 lasso 8 0.08 4.7e-26 -4.59 -6.1 1.1e-09 0.60 1.00 0.00 FALSE
14 The Cancer Genome Atlas Breast Invasive Carcinoma GLS 0.02 0.01 enet 6 0.02 9.6e-05 4.45 -6.2 5.9e-10 0.69 0.11 0.82 FALSE
15 The Cancer Genome Atlas Lung Adenocarcinoma GLS 0.02 0.01 blup 68 0.01 9.7e-03 -6.69 -6.3 3.1e-10 0.75 0.03 0.48 FALSE
16 The Cancer Genome Atlas Prostate Adenocarcinoma GLS 0.16 0.07 lasso 6 0.11 1.3e-11 -4.59 -6.1 9.5e-10 0.61 0.19 0.81 FALSE