Hub : Genes

INPP1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.140	0.0510	4.4e-06	0.140	0.049	0.120	0.130	0.134	1.1e-16	1.1e-06	2.3e-14	1.7e-15	5.5e-16
2	GTEx	Adipose Subcutaneous	0.078	0.0300	3.7e-04	0.009	NA	0.043	NA	0.032	5.3e-02	NA	2.0e-04	NA	1.1e-03
3	GTEx	Artery Coronary	0.145	0.0750	9.8e-03	0.004	NA	0.015	NA	0.043	2.2e-01	NA	9.8e-02	NA	1.4e-02
4	GTEx	Artery Tibial	0.128	0.0412	4.8e-06	0.039	NA	0.053	NA	0.053	4.8e-04	NA	5.5e-05	NA	5.3e-05
5	GTEx	Brain Cerebellar Hemisphere	0.260	0.0800	5.8e-06	0.257	NA	0.136	NA	0.235	2.7e-07	NA	2.4e-04	NA	1.0e-06
6	GTEx	Brain Cerebellum	0.298	0.0770	6.2e-08	0.417	NA	0.346	NA	0.407	1.4e-13	NA	5.0e-11	NA	3.4e-13
7	GTEx	Brain Cortex	0.194	0.0750	5.5e-04	0.158	NA	0.083	NA	0.096	3.9e-05	NA	2.7e-03	NA	1.3e-03
8	GTEx	Brain Hypothalamus	0.121	0.0610	8.7e-03	0.018	NA	-0.008	NA	0.003	1.2e-01	NA	5.5e-01	NA	2.7e-01
9	GTEx	Brain Nucleus accumbens basal ganglia	0.196	0.0680	2.4e-05	0.234	NA	0.123	NA	0.186	6.0e-07	NA	3.6e-04	NA	1.0e-05
10	GTEx	Brain Putamen basal ganglia	0.353	0.1280	7.7e-05	0.101	NA	0.038	NA	0.119	2.2e-03	NA	4.4e-02	NA	9.3e-04
11	GTEx	Breast Mammary Tissue (Female)	0.164	0.0843	2.3e-02	0.017	NA	0.000	NA	0.027	1.0e-01	NA	3.2e-01	NA	5.2e-02
12	GTEx	Colon Sigmoid	0.331	0.0930	1.9e-05	0.054	NA	0.088	NA	0.041	5.5e-03	NA	5.1e-04	NA	1.4e-02
13	GTEx	Colon Transverse	0.141	0.0490	9.5e-06	0.162	NA	0.115	NA	0.151	3.9e-08	NA	4.0e-06	NA	1.1e-07
14	GTEx	Esophagus Mucosa	0.124	0.0370	1.2e-06	0.047	NA	0.102	NA	0.104	4.4e-04	NA	2.7e-07	NA	2.0e-07
15	GTEx	Heart Atrial Appendage	0.094	0.0430	2.0e-03	0.057	NA	0.029	NA	0.046	1.4e-03	NA	1.8e-02	NA	4.0e-03
16	GTEx	Nerve Tibial	0.200	0.0488	1.8e-14	0.232	NA	0.229	NA	0.230	1.9e-16	NA	3.1e-16	NA	2.8e-16
17	GTEx	Pituitary	0.319	0.0950	1.6e-05	0.257	NA	0.185	NA	0.217	3.9e-07	NA	2.1e-05	NA	3.6e-06
18	GTEx	Stomach	0.100	0.0460	2.0e-03	0.049	NA	0.018	NA	0.041	2.2e-03	NA	4.6e-02	NA	4.6e-03
19	GTEx	Testis	0.077	0.0400	6.8e-03	0.002	NA	-0.006	NA	-0.005	2.6e-01	NA	9.4e-01	NA	6.0e-01
20	GTEx	Thyroid	0.082	0.0310	3.8e-04	0.039	NA	0.019	NA	0.036	5.6e-04	NA	1.3e-02	NA	9.3e-04
21	ROSMAP	Brain Pre-frontal Cortex	0.220	0.0387	0.0e+00	0.385	0.356	0.373	0.382	0.384	1.9e-52	9.5e-48	1.7e-50	5.7e-52	2.8e-52
22	YFS	Blood	0.109	0.0289	3.0e-13	0.047	0.048	0.064	0.061	0.065	3.7e-15	2.3e-15	3.1e-20	2.6e-19	1.6e-20

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22
Bipolar Disorder (2018)	0.1	0.2	0.9	0.9	-0.4	-0.2	0.3	-0.2	0.0	-0.3	-0.1	-0.5	-0.3	0.2	0.1	-0.4	-0.6	-0.3	-0.1	0.0	-0.6	0.3	-0.6	-0.1	-0.4
Bipolar Disorder or Schizophrenia	0.2	0.4	2.8	0.6	0.0	-0.2	1.2	0.3	0.6	0.5	0.1	0.2	0.0	-0.6	0.9	0.3	-0.7	0.1	0.6	0.6	0.2	-0.1	-1.2	0.5	-1.7
Depressed Affect (Nagel 2018)	0.4	0.9	2.8	0.8	-0.8	-0.2	-0.2	-0.6	-0.7	-1.1	-0.8	-0.8	0.3	-1.7	-1.6	-1.0	-1.1	-0.7	-0.8	-0.9	-1.1	0.7	-1.3	-0.7	-0.7
Depression (Nagel 2018)	1.3	2.0	3.3	-0.2	-0.7	-0.5	-1.4	-1.6	-1.6	-1.6	-1.6	-1.7	-0.4	-1.8	-1.4	-1.5	-1.8	-1.5	-1.5	-1.4	-1.7	1.5	-1.2	-1.6	-1.1
Intelligence (Savage-Jansen 2018)	0.5	1.7	2.8	-1.5	1.3	0.4	0.4	1.4	1.2	1.5	1.7	1.4	1.2	-1.4	-1.2	1.5	1.5	1.4	1.2	1.2	1.5	-1.5	0.5	1.3	1.1
Neuroticism (Nagel 2018)	1.5	3.4	6.2	0.5	-2.2	-0.7	-1.8	-1.8	-1.8	-2.1	-1.5	-2.0	-0.9	-2.0	-2.1	-2.0	-2.5	-1.9	-1.9	-1.9	-2.2	1.9	-2.4	-1.8	-1.4
Schizophrenia (2018)	0.3	0.6	3.1	-0.0	0.3	-0.0	1.3	0.6	0.7	0.9	0.2	0.7	0.3	-1.0	0.9	0.7	-0.4	0.4	0.8	0.8	0.8	-0.4	-1.0	0.7	-1.8
Schizophrenia vs Biploar Disorder	0.2	0.3	2.4	-1.1	-0.4	0.1	-0.2	-0.0	-0.3	-0.3	0.1	0.2	0.5	-1.1	-0.6	-0.1	0.0	0.0	-0.2	-0.5	-0.1	-0.0	-0.4	-0.1	-1.6
Worry (Nagel 2018)	3.0	6.3	8.9	1.1	-2.6	-1.6	-2.6	-2.8	-2.9	-2.5	-3.0	-2.9	-2.5	-1.1	-1.6	-2.5	-2.8	-2.7	-2.9	-2.9	-2.7	2.7	-1.8	-2.9	-2.4
Alzheimer’s Disease (in mother)	0.7	0.8	5.2	1.0	-0.4	0.6	2.3	0.2	0.3	0.4	0.8	0.3	0.5	-1.5	0.4	0.3	-0.9	0.3	0.3	0.5	0.3	-0.3	-1.9	0.3	1.2
Alzheimer’s Disease (in father)	1.4	1.5	2.6	1.0	0.1	-1.4	-0.7	-1.5	-1.4	-1.3	-1.3	-1.6	-1.2	0.7	-1.4	-1.2	-0.9	-1.6	-1.4	-1.4	-1.2	1.6	0.2	-1.5	-0.3
Alzheimer’s Disease (including proxy)	0.4	0.6	2.4	0.8	-0.2	-0.4	1.0	-0.8	-0.7	-0.5	-0.1	-0.7	-0.6	-0.9	-0.6	-0.5	-1.4	-0.8	-0.7	-0.5	-0.6	0.8	-1.5	-0.8	0.6
Crohns Disease (2017)	0.8	1.7	6.5	1.3	-2.5	1.0	-1.5	-1.0	-1.1	-1.4	-0.8	-0.6	0.1	-0.6	-1.3	-1.3	-1.9	-0.6	-1.2	-0.7	-1.2	0.6	-2.4	-1.1	-1.5
Irritable Bowel Disease (IBD)	0.2	0.5	1.4	0.7	-0.2	1.2	-0.6	0.7	0.4	0.4	1.1	0.9	1.1	0.1	0.2	0.7	0.7	1.0	0.3	0.5	0.6	-1.0	0.2	0.5	-0.5
Ulcerative Colitis (UC)	1.3	2.4	6.2	-0.1	2.1	0.9	0.4	1.6	1.2	1.7	2.1	1.7	1.4	0.3	1.1	1.9	2.5	1.9	1.2	1.1	1.8	-1.9	2.4	1.5	0.2
Major Depression (MDD)	3.7	4.5	10.0	0.0	1.9	1.9	2.6	2.4	2.4	1.7	2.3	2.4	3.2	-1.3	1.9	1.7	2.4	2.3	2.2	2.2	1.5	-2.3	2.1	2.5	0.8
Reaction Time	0.2	0.4	2.9	0.0	-1.5	0.3	-0.5	-0.0	-0.3	0.2	-0.3	0.0	-0.7	1.7	0.5	0.2	-0.8	0.2	-0.1	-0.1	0.2	-0.2	-1.5	-0.2	-0.3
Verbal and Numeric Reasoning (VNR)	0.7	1.7	3.4	-1.1	0.6	0.8	0.2	1.5	1.2	1.7	1.8	1.6	0.9	-1.0	-0.8	1.8	1.5	1.6	1.3	1.2	1.8	-1.7	0.2	1.4	1.1
Breast Cancer	0.4	1.0	3.6	-1.2	0.5	1.8	0.7	1.2	0.8	0.2	0.5	0.9	1.1	1.9	1.2	-0.1	1.4	1.1	0.6	0.8	-0.1	-1.2	0.9	1.1	-0.3
Ovarian Cancer	0.7	0.9	3.9	-0.9	1.0	-0.9	-1.4	-0.8	-0.7	-1.1	-0.5	-0.8	-0.2	0.6	-2.0	-1.2	0.0	-1.0	-0.8	-0.7	-0.9	1.0	1.2	-0.8	0.2
Prostate Cancer	0.8	1.2	2.6	-1.2	0.1	0.5	1.3	1.2	1.2	1.1	1.4	1.1	0.5	-0.9	-0.1	1.3	0.9	1.2	1.1	1.2	1.2	-1.2	-0.4	1.1	1.6
Age at First Birth	1.0	1.4	4.7	-0.3	2.0	-0.1	-1.1	1.0	0.9	0.9	1.0	0.8	0.9	1.5	1.4	1.1	1.8	1.0	1.0	0.5	1.3	-1.0	2.2	1.0	1.2
Bipolar Disorder (2011)	0.5	0.5	3.0	0.0	-0.4	0.3	-0.7	-0.7	-0.4	-0.6	0.0	-0.6	0.4	-1.7	-0.5	-0.7	-1.4	-0.7	-0.4	-0.2	-0.6	0.8	-1.3	-0.6	0.1
Body Mass Index (BMI) (2010)	0.8	1.1	3.5	-0.4	-0.2	1.2	1.3	1.1	0.8	1.1	1.0	1.1	1.4	-1.9	0.8	1.2	0.8	1.3	0.9	0.8	0.9	-1.3	-0.2	1.0	0.8
Coronary Artery Disease (CAD)	2.1	2.5	6.1	0.0	-0.6	1.3	0.1	1.9	1.7	1.9	2.5	1.9	1.7	-1.4	0.6	1.9	1.8	1.9	1.8	1.7	1.7	-1.9	0.5	1.8	0.8
Crohns Disease (2012)	1.6	2.5	10.7	0.5	-3.3	0.4	-1.5	-1.4	-1.5	-1.5	-1.2	-1.2	-1.1	-0.9	-1.9	-1.4	-2.1	-1.2	-1.6	-1.2	-1.4	1.2	-2.5	-1.5	-1.7
Mean Putamen Volume	0.4	0.5	1.4	0.5	1.1	0.0	0.0	0.3	0.2	0.6	0.5	0.7	0.1	0.6	1.0	0.8	0.9	0.4	0.5	0.2	1.1	-0.4	1.2	0.3	1.2
Fasting Glucose	1.6	1.9	5.0	-0.2	0.8	1.8	2.2	1.5	1.1	1.3	1.4	1.8	1.2	0.2	1.1	1.5	1.7	1.5	1.1	1.3	1.9	-1.6	0.8	1.4	0.8
HbA1C	0.2	0.2	1.1	-0.4	0.5	1.1	0.1	-0.2	0.1	-0.5	0.3	0.0	1.0	-0.6	0.2	-0.5	0.2	-0.1	-0.1	0.0	-0.6	0.1	0.9	-0.1	0.7
HDL Cholesterol	0.5	0.9	2.2	0.6	0.4	-0.3	-0.7	-1.0	-0.7	-1.0	-1.2	-1.1	-0.8	0.4	-1.1	-1.2	-0.8	-1.5	-1.0	-0.8	-1.2	1.4	0.8	-0.9	-0.9
LDL Cholesterol	1.2	1.8	8.5	-0.8	2.9	0.6	0.7	0.8	0.7	1.1	1.1	1.1	0.6	1.7	1.1	1.2	2.2	1.1	1.1	0.5	1.4	-1.1	2.8	0.8	1.2
Lupus	5.9	8.9	30.2	-1.6	-3.2	1.7	1.6	3.3	3.1	3.4	2.5	2.8	3.5	-5.5	0.6	3.5	1.8	3.3	3.2	3.1	3.5	-3.4	-1.0	3.2	2.5
Neuroticism (2016)	3.1	4.5	8.2	0.5	-1.5	0.0	-1.8	-2.4	-2.3	-2.7	-2.4	-2.9	-1.9	-0.6	-2.5	-2.6	-2.7	-2.4	-2.5	-2.1	-2.6	2.4	-1.7	-2.4	0.3
Primary Biliary Cirrhosis	4.0	5.6	39.1	-0.2	-6.3	-0.3	-0.9	-1.7	-1.8	-1.5	-0.9	-1.5	-0.6	-4.2	-1.2	-1.2	-3.6	-1.4	-1.7	-1.5	-1.3	1.5	-4.9	-1.9	-0.9
Rheumatoid Arthritis	3.2	4.3	14.0	-0.3	-1.5	-0.1	0.5	2.4	2.3	2.5	2.1	2.2	2.8	-3.7	1.4	2.4	1.4	2.2	2.5	2.3	2.4	-2.3	-0.5	2.3	1.3
Schizophrenia (2014)	0.4	0.8	3.5	0.1	-0.3	0.1	1.4	0.6	0.8	0.9	0.6	0.6	0.6	-1.9	0.2	0.7	-0.6	0.5	0.9	0.9	0.7	-0.5	-1.5	0.7	-1.6
Triglycerides	3.4	5.5	13.6	-0.3	3.5	0.1	1.3	2.5	2.2	1.8	2.6	2.1	2.1	1.7	2.8	1.9	3.7	2.4	2.1	2.1	1.9	-2.5	3.5	2.4	2.8
Type 2 Diabetes (T2D) (2012)	4.2	4.9	10.0	-1.5	1.7	0.6	1.6	2.3	2.2	2.8	2.8	2.8	1.8	0.2	2.3	2.9	2.0	2.0	3.2	2.4	2.4	-2.0	0.7	2.2	3.1
Ulcerative Colitis	0.2	0.3	2.7	-0.3	0.7	0.1	-0.9	-0.0	-0.2	0.2	-0.0	-0.1	-0.5	1.0	0.2	0.3	0.9	0.1	-0.2	-0.4	0.2	-0.1	1.7	-0.1	-0.5
Blood Eosinophil Count	0.2	1.5	17.6	0.6	2.7	-0.0	0.2	-0.3	-0.4	-0.7	0.6	-0.2	-0.7	4.2	0.7	-0.7	0.6	-0.3	-0.5	-0.5	-0.5	0.3	1.5	-0.3	-0.8
Blood Platelet Count	0.4	4.5	28.8	-2.8	5.4	0.3	3.0	0.6	0.8	0.5	1.0	0.8	-0.5	3.9	1.5	0.5	2.9	0.5	0.6	0.2	0.6	-0.5	4.7	0.8	1.2
Blood Red Count	0.3	3.2	16.6	-0.5	0.0	0.1	-2.9	-1.7	-1.8	-2.2	-1.4	-1.6	-2.3	4.1	0.3	-2.1	-0.9	-1.5	-1.9	-2.0	-2.0	1.5	0.2	-1.8	-0.6
Blood White Count	0.4	3.2	14.7	-1.1	2.8	0.1	1.6	1.7	1.8	1.0	2.4	2.0	1.1	3.8	1.7	1.0	2.0	1.5	1.4	1.7	1.1	-1.6	1.7	1.8	0.3
Heel T-Score	0.4	3.5	45.2	-2.5	2.2	0.3	0.6	1.0	1.0	0.4	1.1	1.1	-1.2	6.7	2.0	0.3	1.5	1.0	0.8	1.0	0.4	-1.0	1.4	1.1	0.4
BMI	0.1	0.5	1.8	-0.3	-0.5	-0.6	0.8	0.7	1.1	0.5	-0.1	0.6	0.3	1.1	0.8	0.3	0.3	0.5	1.0	1.2	0.4	-0.5	-0.1	0.8	1.3
Height	0.6	12.2	59.3	-0.6	-3.8	-1.0	-3.9	-3.4	-3.5	-3.6	-3.0	-3.5	-0.8	-7.7	-4.9	-3.3	-3.4	-3.3	-3.5	-3.4	-3.5	3.3	-2.1	-3.5	-0.8
Waist Hip Ratio (WHR)	0.3	1.2	3.4	0.3	1.3	-0.2	1.3	1.1	0.9	0.8	1.0	1.3	1.8	-0.8	1.3	0.8	1.4	1.2	0.9	1.2	0.9	-1.2	1.1	1.0	0.5
Systolic Blood Pressure	1.4	7.0	52.3	-0.6	-0.9	-1.2	-2.1	-2.4	-2.1	-2.1	-2.8	-2.2	-4.8	7.2	-0.5	-2.2	-1.3	-2.3	-2.3	-2.7	-2.2	2.3	0.3	-2.2	-2.2
Smoking Status	0.1	0.3	1.1	1.0	0.5	-0.8	0.3	0.5	0.3	0.3	0.6	0.4	0.9	-0.7	0.1	0.4	0.4	0.6	0.2	0.4	0.5	-0.6	-0.1	0.4	1.1
Allergy or Eczema	2.2	5.8	18.1	-2.7	-3.5	1.3	-2.0	-2.2	-2.1	-2.0	-1.9	-2.1	-2.7	-1.1	-2.4	-2.1	-3.7	-2.3	-2.2	-1.9	-2.1	2.3	-4.3	-2.3	-1.2
Cardiovascular Disease	1.3	4.3	11.4	-1.4	-2.1	-1.1	-1.0	-2.0	-1.9	-1.7	-2.5	-1.6	-3.4	3.1	-1.3	-1.7	-2.8	-1.9	-1.8	-1.9	-1.6	1.9	-3.1	-1.9	-2.0
Hypothyroidism (self reported)	2.5	5.8	36.5	-0.2	-2.9	-0.3	2.6	2.1	2.4	2.3	1.1	2.0	2.6	-6.0	1.3	2.4	0.1	1.7	2.7	2.6	2.5	-1.7	-2.0	2.2	2.5
Respiratory disease	0.8	1.7	7.8	-1.9	-2.6	-0.9	-1.3	-0.9	-0.6	-1.0	-0.5	-0.9	-1.6	0.3	-0.8	-1.0	-2.0	-0.9	-0.9	-0.7	-1.1	0.9	-2.8	-0.8	0.1
Type 2 Diabetes (T2D) (2018)	1.7	3.2	5.2	-1.1	1.7	-0.5	0.8	2.1	2.1	2.1	2.1	2.3	2.2	0.3	0.4	1.9	2.1	2.0	2.1	2.2	2.1	-2.0	0.9	2.1	1.1
Lung FEV1/FVC ratio	0.2	0.8	3.2	-1.8	-0.8	-0.5	-0.7	-0.5	-0.4	-0.7	-1.2	-0.5	-0.7	1.2	-1.7	-0.9	-0.3	-0.6	-0.7	-0.5	-1.0	0.6	-0.3	-0.5	-1.6
Lung FVC	2.1	10.5	19.0	-0.6	-2.7	-2.1	-4.4	-3.5	-3.4	-3.5	-3.9	-3.7	-4.2	1.1	-2.9	-3.6	-2.8	-3.6	-3.6	-3.7	-3.6	3.6	-1.4	-3.5	-2.5
Neuroticism	2.5	6.1	10.0	1.0	-2.2	-2.5	-3.2	-2.6	-2.6	-2.7	-2.8	-2.9	-1.8	-1.3	-2.8	-2.7	-2.7	-2.6	-2.7	-2.7	-2.8	2.6	-1.6	-2.6	-1.5
Chronotype (morning person)	0.5	1.1	10.1	-0.5	0.7	0.6	-0.9	-0.4	-0.5	0.1	-0.1	-0.2	-1.4	3.2	0.0	-0.1	0.8	-0.4	-0.4	-0.7	-0.1	0.4	2.1	-0.4	-1.9
Hair Pigment	0.1	3.3	10.2	3.2	-2.7	-1.5	-1.4	-1.7	-1.8	-2.5	-1.6	-1.6	-0.6	-1.3	-1.6	-2.2	-1.9	-1.5	-1.9	-1.6	-2.4	1.5	-1.2	-1.8	-0.6
Tanning	0.1	1.0	3.5	0.6	-0.3	-1.1	-1.9	-1.2	-0.9	-0.8	-1.2	-1.0	-1.3	0.3	-1.1	-0.8	-1.1	-1.2	-1.0	-0.8	-0.7	1.2	-0.4	-1.1	-0.7
Hand grip strength (left)	2.0	5.3	9.4	1.3	-1.0	-1.0	-2.8	-2.6	-2.5	-2.9	-2.7	-2.8	-1.0	-0.8	-2.5	-2.9	-2.2	-2.7	-2.5	-2.4	-3.1	2.7	-0.8	-2.6	-1.9
Number of treatments/medications taken	1.0	1.8	9.1	-1.8	-2.7	-0.7	-2.0	-1.0	-1.1	-0.5	-1.5	-0.8	-1.7	-0.7	-0.3	-0.3	-1.8	-0.7	-1.0	-0.8	-0.3	0.7	-3.0	-1.1	-0.6
Average weekly spirits intake	1.4	1.7	4.8	0.9	-1.3	-0.9	-1.5	-1.2	-1.2	-1.6	-0.9	-1.3	0.0	-0.4	-0.0	-1.9	-1.5	-1.3	-1.3	-1.0	-1.9	1.3	-1.4	-1.2	-2.2
Sensitivity / hurt feelings	0.6	1.0	3.2	-1.6	-1.0	-0.4	-1.8	-0.7	-0.7	-1.1	-0.3	-0.8	-1.0	0.2	-1.3	-1.1	-1.2	-0.7	-0.9	-0.7	-1.1	0.7	-1.7	-0.7	-0.8
Frequency of depressed mood in last 2 weeks	1.0	1.4	2.7	-1.1	-1.0	-1.7	-0.4	-1.1	-0.9	-1.3	-1.1	-1.2	-0.3	-1.4	-1.4	-1.4	-1.5	-1.2	-1.0	-0.9	-1.4	1.2	-1.3	-1.1	-1.1
Hearing difficulty/problems: Yes	0.9	1.4	6.1	1.1	0.7	1.9	0.1	1.0	0.8	0.8	0.8	1.0	1.2	0.2	0.7	1.0	2.0	1.0	0.9	0.7	1.0	-1.1	2.5	1.0	2.1
Relative age of first facial hair	2.6	5.4	9.2	-0.3	-1.6	-1.5	-1.2	-2.9	-2.8	-2.5	-2.1	-2.8	-2.6	-0.8	-2.1	-2.4	-2.8	-2.8	-2.8	-3.0	-2.4	2.8	-1.4	-2.9	-1.8
Other serious medical condition/disability diagnosed by doctor	3.0	3.8	7.0	-1.5	-1.0	2.1	2.4	2.0	2.1	2.2	2.2	2.2	1.6	-2.6	1.5	2.3	0.7	1.9	2.1	2.1	2.3	-1.9	-0.9	2.0	2.0
Ever used hormone-replacement therapy (HRT)	2.9	3.7	8.3	2.0	-0.8	0.0	-2.7	-2.3	-2.9	-2.4	-1.7	-2.4	-1.3	0.1	-1.5	-2.0	-1.3	-1.8	-2.6	-2.8	-2.1	1.8	-0.1	-2.6	0.2
Ever had hysterectomy (womb removed)	0.7	0.8	2.9	0.8	1.5	0.4	1.3	0.8	0.7	0.6	0.7	0.6	0.4	1.1	0.0	0.6	1.2	0.9	0.7	0.8	0.5	-0.9	1.0	0.8	1.7
Systolic blood pressure, automated reading	1.6	4.6	16.6	0.6	-0.9	0.1	-2.1	-2.3	-2.4	-2.2	-2.6	-2.1	-3.5	4.1	-0.8	-2.0	-1.4	-2.0	-2.4	-2.6	-2.1	2.1	-0.3	-2.3	-1.2
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	3.3	0.5	0.9	-1.8	-0.8	1.1	1.2	1.2	1.7	1.4	1.5	-0.8	1.0	1.3	1.3	1.0	1.2	1.3	1.5	-1.0	0.7	1.1	1.1
Angina	0.3	0.4	2.2	0.9	0.2	0.8	-0.5	-0.6	-0.4	-0.5	-1.5	-0.7	-0.8	1.3	0.3	-0.6	-0.2	-0.7	-0.4	-0.3	-0.5	0.7	0.3	-0.6	-0.2
Medication for hormone replacement therapy	1.3	1.5	5.1	2.3	0.3	0.3	-0.7	-1.4	-1.9	-1.0	-1.2	-1.5	-1.8	0.7	-0.4	-0.8	-0.3	-1.1	-1.6	-1.8	-0.8	1.1	0.8	-1.6	-0.5
Vitamin and mineral supplements	0.4	0.5	1.7	-1.3	0.3	-0.1	0.5	-0.7	-0.7	-0.9	-1.0	-0.5	-0.3	0.3	-1.1	-1.0	-0.1	-0.6	-0.8	-0.5	-0.8	0.6	0.6	-0.7	0.3
Supplements: Zinc	1.0	1.1	3.9	0.8	0.0	-0.6	-2.0	-1.2	-1.2	-0.5	-1.1	-1.1	-1.0	-0.5	-1.7	-0.4	-1.2	-1.1	-0.9	-1.1	-0.4	1.1	-0.8	-1.2	-0.9
Medication: Co-codamol	0.8	0.9	2.2	-1.2	-0.9	-0.4	0.5	1.1	1.1	1.1	0.5	0.8	-0.1	-0.2	0.5	1.3	0.6	1.1	1.0	1.0	1.2	-1.1	-0.6	1.1	1.5
Medication: Metformin	0.6	0.9	3.0	-1.5	0.3	0.2	0.1	1.0	0.9	0.8	1.2	1.1	0.7	1.7	0.1	0.7	0.9	1.2	0.8	1.3	0.8	-1.2	-0.2	0.9	0.2
Diabetes (father)	1.1	1.3	4.0	-1.2	-0.2	2.0	0.5	1.2	1.0	1.3	0.6	1.3	1.6	-1.6	1.0	1.3	1.1	1.3	1.2	0.7	1.3	-1.3	0.2	1.2	0.1
Diabetes (mother)	1.5	2.0	3.5	-0.6	1.4	1.7	0.7	1.6	1.7	1.6	1.2	1.7	1.5	0.3	1.2	1.6	1.4	1.4	1.9	1.7	1.6	-1.4	1.0	1.6	0.2
Severe depression (siblings)	2.2	2.4	5.0	0.5	-1.6	-1.3	0.1	-1.6	-1.5	-2.2	-1.6	-1.6	-0.7	-1.5	-0.9	-2.2	-2.2	-1.7	-1.6	-1.7	-2.1	1.7	-1.5	-1.6	-0.5
Pack years adult smoking proportion	0.9	1.3	2.8	-0.9	0.4	0.2	-0.1	1.4	1.2	1.3	1.3	1.4	0.3	1.5	0.7	1.6	1.1	1.7	1.2	1.3	1.5	-1.6	-0.3	1.3	0.5
Impedance of leg (right)	0.1	0.3	1.5	-0.3	-0.8	-0.3	0.3	-0.4	-0.6	0.1	-0.2	-0.2	-0.6	-0.7	0.5	0.3	-0.7	-0.4	-0.3	-0.6	0.1	0.3	-1.0	-0.5	-1.2
Leg fat-free mass (left)	0.3	1.7	3.2	-0.2	-0.9	-1.2	-1.3	-1.5	-1.2	-1.8	-1.4	-1.6	-0.6	-0.6	-1.6	-1.8	-1.1	-1.5	-1.4	-1.3	-1.7	1.5	-0.1	-1.4	0.9
Trunk fat percentage	0.7	2.8	4.5	-0.0	-2.1	-1.8	-1.3	-2.0	-1.9	-1.9	-2.1	-1.9	-1.8	1.1	-0.7	-1.7	-1.9	-1.8	-1.9	-1.9	-1.7	1.8	-1.1	-2.0	0.8
Hand grip strength (right)	0.8	2.1	4.4	2.1	0.1	-1.0	-1.2	-1.6	-1.5	-1.8	-1.7	-1.9	0.0	-1.1	-1.1	-1.8	-1.0	-1.8	-1.4	-1.6	-1.9	1.8	0.5	-1.5	-1.0
Townsend deprivation index at recruitment	0.6	0.8	4.5	-2.1	0.2	-2.1	-1.2	-0.6	-0.2	-0.3	-0.7	-0.7	-1.2	1.4	-0.9	-0.4	-0.4	-0.7	-0.2	-0.1	-0.4	0.7	0.0	-0.4	-0.1
Current tobacco smoking	0.2	0.3	1.8	-0.8	-0.9	-1.3	-0.5	-0.3	-0.5	-0.4	0.3	-0.2	-0.5	0.3	-1.0	-0.2	-0.4	-0.2	-0.6	-0.3	-0.1	0.2	-1.1	-0.4	-0.3
Average weekly fortified wine intake	0.3	0.4	1.7	-1.1	-0.9	0.7	0.2	0.4	0.2	0.6	0.6	0.6	0.0	-1.3	-1.0	0.7	-0.0	0.6	0.2	0.2	0.8	-0.6	-0.6	0.3	-0.3
Maternal smoking around birth	0.2	0.3	1.9	1.3	0.6	-1.0	0.0	-0.2	-0.1	-0.4	-0.2	-0.3	0.4	-0.7	0.6	-0.3	-0.0	-0.1	-0.0	0.1	-0.2	0.1	0.2	-0.2	1.4
Fed-up feelings	1.0	1.7	5.1	0.4	-0.1	-2.2	-1.4	-1.3	-1.3	-1.6	-1.0	-1.5	-0.5	-0.4	-2.1	-1.5	-1.2	-1.2	-1.4	-1.6	-1.6	1.2	-0.7	-1.3	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	1.8	2.4	4.2	0.3	-0.7	-1.2	-1.3	-1.9	-2.0	-1.5	-1.8	-2.0	-1.8	-0.7	-0.8	-1.4	-1.6	-1.7	-1.8	-2.0	-1.5	1.8	-0.7	-2.0	-1.6
Relative age voice broke	0.3	0.5	1.2	-0.4	-0.1	-0.4	-0.4	-0.8	-0.6	-0.8	-0.5	-0.6	-0.9	0.9	-0.5	-0.8	-1.1	-0.9	-0.7	-0.9	-0.6	0.9	-0.4	-0.7	0.5
Taking other prescription medications	0.7	1.1	7.2	-2.7	-1.8	0.3	-1.3	-0.5	-0.8	-0.4	-0.7	-0.5	-1.3	-1.3	-0.3	0.0	-0.9	-0.2	-0.7	-0.6	-0.0	0.2	-1.6	-0.6	1.2
Age when periods started (menarche)	1.3	3.1	5.1	-0.1	-1.2	0.1	-2.2	-2.1	-2.1	-2.2	-1.6	-1.9	-2.0	1.7	-0.9	-2.3	-1.3	-2.0	-2.2	-2.1	-2.2	2.0	-0.3	-2.0	-1.4
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	4.4	2.1	0.7	0.1	-0.9	-0.3	-0.5	-0.2	-0.3	-0.4	-0.0	-0.0	-0.2	-0.0	0.3	-0.3	-0.3	-0.3	-0.0	0.2	0.5	-0.4	0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.4	12.5	-1.1	1.5	1.2	0.4	0.6	0.8	0.4	0.9	0.9	0.1	3.5	1.9	0.1	1.3	0.4	0.7	0.6	0.5	-0.4	1.7	0.7	0.5
Tinnitus: Yes, but not now, but have in the past	0.2	0.3	2.9	0.4	1.0	0.0	0.7	-0.1	0.1	0.3	-0.2	-0.3	-0.4	0.1	-0.0	0.1	0.8	-0.3	0.0	-0.3	0.1	0.3	1.7	0.1	0.2
Qualifications: CSEs or equivalent	0.3	0.4	2.7	1.0	-0.5	-1.6	0.2	-0.5	-0.1	-0.3	-0.8	-0.7	-1.0	0.4	0.4	-0.5	-0.6	-0.8	-0.1	-0.4	-0.5	0.8	-0.2	-0.4	-0.1
Serious illness, injury or assault to yourself	1.9	2.3	3.7	-1.2	0.7	-0.3	0.5	1.8	1.8	1.8	1.5	1.9	1.9	-1.0	0.7	1.8	1.5	1.9	1.9	1.8	1.8	-1.9	0.5	1.8	0.9
High blood pressure	0.6	1.7	8.6	-1.1	-1.7	-0.4	-0.6	-0.9	-1.0	-0.8	-1.5	-0.6	-2.1	2.5	-0.9	-0.7	-1.9	-0.6	-1.0	-0.8	-0.6	0.7	-2.9	-0.9	-0.8
Hayfever, allergic rhinitis or eczema	1.5	3.3	9.9	-2.2	-2.9	1.6	-1.5	-1.5	-1.6	-1.4	-1.3	-1.5	-1.9	-1.6	-2.0	-1.4	-2.6	-1.4	-1.7	-1.5	-1.5	1.4	-3.1	-1.6	-1.1
Multivitamins +/- minerals	0.3	0.4	3.8	0.6	-0.6	0.4	0.8	0.4	0.5	0.5	0.6	0.2	0.2	-0.5	0.7	0.4	-0.9	0.3	0.5	0.4	0.3	-0.3	-1.9	0.4	-0.4
Stomach or abdominal pain in last month	4.1	5.1	8.5	0.8	-2.2	-1.5	-2.6	-2.6	-2.5	-2.7	-2.0	-2.5	-1.5	-1.7	-1.1	-2.6	-2.9	-2.5	-2.6	-2.5	-2.6	2.5	-2.2	-2.6	-1.4
Supplements: Glucosamine	0.7	0.9	3.9	-0.9	-2.0	0.4	-0.6	-0.9	-0.8	-0.8	-1.0	-0.8	-0.8	-0.3	-1.2	-0.9	-1.3	-0.8	-0.8	-0.6	-0.8	0.8	-1.5	-0.8	-0.8
Diverticular disease/diverticulitis (self-reported)	0.4	0.4	2.1	-0.5	0.9	0.3	1.4	0.5	0.3	0.2	0.8	0.4	0.9	-1.1	0.0	0.4	0.8	0.7	0.2	-0.0	0.4	-0.7	0.4	0.5	0.6
Medication: Atenolol	0.6	0.8	3.2	-1.8	-1.3	-1.1	-0.8	-0.4	-0.3	-0.5	-1.0	-0.5	-1.3	1.6	-1.1	-0.6	-0.6	-0.3	-0.6	-0.3	-0.6	0.3	-1.2	-0.4	-0.9
Medication: Levothyroxine sodium	3.7	6.2	24.9	-0.7	-1.3	0.1	2.4	2.6	2.8	2.8	1.8	2.5	2.9	-5.0	1.7	2.8	1.5	2.3	3.0	2.8	2.9	-2.4	-0.5	2.7	2.4
Sitting height	0.3	1.8	5.6	-1.7	-1.7	0.2	-1.5	-1.4	-1.3	-1.6	-1.1	-1.3	-0.4	-2.4	-1.4	-1.4	-1.1	-1.3	-1.4	-1.4	-1.5	1.3	-0.4	-1.4	0.7
Chronic bronchitis/emphysema (father)	1.1	1.3	3.6	-1.1	-0.8	0.8	0.2	-1.3	-1.4	-1.0	-1.6	-1.2	-1.9	0.7	-0.4	-0.8	-1.3	-1.1	-1.3	-1.4	-0.8	1.1	-1.1	-1.3	0.1
High blood pressure (mother)	2.2	3.1	10.0	3.2	0.2	-0.2	-1.4	-1.9	-1.7	-2.2	-1.8	-1.9	-1.3	1.4	-1.1	-2.3	-0.4	-1.9	-1.9	-2.1	-2.2	1.9	2.2	-1.7	-0.8
Body mass index (BMI)	0.1	0.6	1.6	0.5	-0.5	-0.8	0.1	-0.8	-0.5	-1.0	-1.2	-0.9	-0.4	1.1	-0.1	-1.0	-0.9	-0.8	-0.7	-0.5	-0.9	0.8	-0.3	-0.7	1.3
Impedance of leg (left)	0.1	0.4	1.1	0.2	-0.7	-0.5	-0.6	-0.7	-1.0	-0.2	-0.5	-0.5	-0.8	-0.1	0.2	0.0	-0.6	-0.7	-0.6	-0.9	-0.2	0.7	-0.4	-0.8	-1.0
Leg predicted mass (left)	0.3	1.7	3.2	-0.2	-1.0	-1.1	-1.4	-1.5	-1.2	-1.8	-1.5	-1.6	-0.6	-0.7	-1.6	-1.8	-1.1	-1.5	-1.4	-1.3	-1.7	1.5	-0.2	-1.4	0.9
Trunk fat mass	0.8	3.3	5.4	-0.1	-2.1	-1.6	-1.6	-2.2	-2.1	-2.2	-2.3	-2.2	-1.6	0.4	-1.1	-2.0	-2.0	-2.0	-2.1	-2.0	-2.0	2.0	-1.1	-2.2	1.0
Waist circumference	0.2	0.8	1.8	0.3	-0.7	-1.4	-0.1	-1.0	-0.9	-1.2	-1.2	-1.0	-0.1	-0.4	-0.1	-1.1	-1.0	-0.8	-1.0	-0.7	-1.0	0.8	-0.6	-1.0	1.3
Number of incorrect matches in round	0.3	0.4	2.1	0.0	-0.2	1.4	1.5	0.3	0.2	0.6	0.9	0.5	0.1	-0.5	0.3	0.6	-0.4	0.3	0.3	0.1	0.6	-0.3	-1.1	0.3	-0.9
Past tobacco smoking	0.3	0.6	2.4	-1.3	-1.1	0.3	-0.6	-0.7	-0.7	-0.5	-0.5	-0.3	-1.0	0.2	-0.5	-0.3	-0.9	-0.6	-0.7	-0.8	-0.4	0.6	-0.9	-0.7	-1.6
Alcohol usually taken with meals	0.4	0.7	4.9	0.1	-0.9	1.1	0.2	0.6	0.6	0.9	0.6	0.8	1.0	-2.2	0.3	1.0	0.1	0.7	0.8	0.5	1.0	-0.7	-0.5	0.6	0.1
Nervous feelings	2.5	4.7	7.5	1.3	-1.0	-1.6	-2.4	-2.5	-2.7	-2.4	-2.0	-2.5	-2.4	0.5	-1.8	-2.3	-1.9	-2.3	-2.7	-2.7	-2.4	2.3	-0.7	-2.6	-2.5
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.8	5.2	-0.6	-0.9	-2.3	-0.6	-1.4	-1.1	-1.0	-1.3	-1.5	-1.5	-0.3	-0.5	-1.1	-1.7	-1.6	-1.1	-1.3	-1.2	1.5	-1.3	-1.3	-1.9
Hearing difficulty/problems with background noise	0.2	0.4	3.6	-1.0	-0.1	0.1	-1.9	-0.1	-0.1	-0.2	0.4	-0.1	0.1	-0.9	-0.8	0.0	-0.1	-0.1	-0.2	-0.1	-0.0	0.1	-0.3	-0.1	1.2
Hair/balding pattern: Pattern 2	0.4	0.5	1.5	1.0	1.0	-0.1	-0.1	0.5	0.6	0.6	0.1	0.5	0.5	1.1	-0.7	0.6	0.9	0.6	0.7	0.9	0.7	-0.6	1.2	0.5	0.5
Had menopause	1.1	1.4	6.2	1.0	-1.8	0.3	-1.0	-0.8	-1.2	-1.0	-0.7	-0.9	-0.1	-2.4	-1.2	-0.8	-1.5	-0.5	-1.1	-0.5	-0.9	0.5	-2.5	-1.0	0.8
Had other major operations	0.5	0.7	3.3	-1.8	-0.1	-1.4	-1.3	-0.6	-0.5	-0.6	-0.9	-0.8	-1.1	0.5	-0.6	-0.5	-0.2	-0.7	-0.5	-0.7	-0.5	0.7	0.0	-0.6	0.6
Forced vital capacity (FVC)	1.1	4.3	9.7	-0.9	-2.2	0.2	-3.1	-2.2	-2.3	-2.4	-1.8	-2.3	-1.4	-2.5	-1.9	-2.4	-1.6	-2.2	-2.4	-2.4	-2.5	2.2	-0.5	-2.3	-1.6
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	13.1	-1.4	1.1	1.8	-0.4	-0.0	0.2	-0.4	0.1	0.2	-0.6	3.6	0.6	-0.7	0.2	-0.2	-0.0	0.1	-0.4	0.2	0.6	0.1	-0.1
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	2.3	1.5	0.2	-1.5	-0.7	-0.9	-0.8	-0.7	-0.7	-0.8	-0.0	-1.3	0.2	-0.6	-0.5	-1.0	-0.6	-0.9	-0.5	1.0	0.9	-0.8	-0.1
Qualifications: None of the above	0.9	1.9	15.8	1.0	1.0	0.1	-0.4	-1.2	-1.2	-0.5	-1.7	-1.2	-2.8	4.0	0.2	-0.4	-0.3	-1.0	-1.0	-1.4	-0.5	1.1	0.7	-1.2	-0.9
Financial difficulties in last 2 years	2.1	2.9	6.5	-0.4	-1.9	-0.9	-0.6	-1.9	-1.7	-1.7	-1.7	-1.8	-2.2	0.1	-1.0	-1.8	-2.6	-1.8	-1.9	-1.7	-1.7	1.8	-2.3	-1.9	-1.3
Mouth/teeth dental problems	0.9	1.4	2.7	1.2	1.6	1.4	1.2	1.1	1.1	1.1	1.3	1.1	1.4	-0.0	1.5	1.1	1.3	0.9	1.3	0.8	1.2	-0.9	1.6	1.1	1.4
Heart attack	1.5	1.9	6.7	1.3	-0.6	0.3	-2.6	-1.5	-1.5	-1.2	-1.8	-1.3	-1.9	0.7	-0.8	-1.1	-1.3	-1.5	-1.4	-1.5	-1.0	1.5	-0.9	-1.5	-1.1
Allergy	1.9	4.4	15.9	2.0	3.4	-1.1	1.4	1.8	2.0	1.9	1.7	1.9	2.2	1.4	2.1	1.8	3.1	1.4	2.1	1.8	2.0	-1.4	4.0	2.0	0.7
Pain all over the body in last month	0.3	0.4	3.7	-0.8	0.5	1.9	0.4	-0.2	-0.4	-0.5	0.1	-0.1	-0.1	0.5	1.0	-0.5	0.0	-0.2	-0.4	-0.2	-0.5	0.2	0.2	-0.3	0.7
Diabetes (self-reported)	1.4	2.1	3.9	0.0	1.2	-0.3	0.4	1.7	1.6	1.4	2.0	1.8	1.8	0.8	0.8	1.5	1.7	1.8	1.6	1.7	1.7	-1.8	0.6	1.6	1.4
Hayfever/allergic rhinitis (self-reported)	2.4	3.1	5.2	-1.3	-1.8	0.9	-1.2	-1.8	-1.8	-1.8	-1.7	-1.8	-1.8	-1.1	-2.0	-1.9	-2.3	-1.8	-2.1	-1.7	-1.9	1.8	-2.2	-1.9	-1.5
Medication: Ramipril	0.3	0.4	2.7	0.8	1.6	0.2	0.6	0.2	0.1	0.3	-0.1	0.2	-0.1	1.0	0.5	0.4	0.8	0.3	0.2	0.0	0.4	-0.3	1.2	0.2	1.0
Medication: Simvastatin	0.7	1.0	6.1	-0.0	1.7	-0.2	1.8	0.5	0.5	0.7	-0.2	0.6	-0.3	2.5	0.9	0.8	1.4	0.7	0.5	0.0	0.9	-0.6	1.8	0.6	-0.3
Fluid intelligence score	0.6	1.3	3.1	-0.4	0.3	1.0	-0.3	1.4	1.1	1.6	1.3	1.5	0.8	-0.7	-0.9	1.8	1.1	1.4	1.2	1.2	1.7	-1.4	-0.1	1.3	0.6
Illnesses of siblings	0.2	0.2	1.1	-0.6	-0.7	1.1	0.0	-0.3	-0.3	-0.2	-0.0	-0.2	0.3	-0.8	-0.8	-0.1	-0.5	-0.2	-0.2	0.0	-0.3	0.2	-0.6	-0.4	-0.5
Neuroticism score	2.2	4.6	6.7	0.5	-1.7	-2.2	-2.4	-2.3	-2.4	-2.4	-2.3	-2.6	-1.9	-1.0	-2.2	-2.4	-2.3	-2.2	-2.5	-2.5	-2.5	2.2	-1.4	-2.4	-1.5
Weight	0.7	3.5	5.9	0.1	-1.7	-1.3	-1.8	-2.2	-2.0	-2.4	-2.4	-2.3	-1.3	-0.6	-1.7	-2.3	-2.0	-2.1	-2.2	-2.0	-2.2	2.2	-0.9	-2.2	0.8
Impedance of arm (right)	0.6	2.8	7.7	-1.0	-2.7	-1.7	-2.2	-1.6	-2.0	-1.0	-0.8	-1.3	-2.8	1.1	-1.2	-0.7	-1.6	-1.3	-1.7	-1.9	-0.8	1.3	-1.8	-1.8	-2.2
Arm fat percentage (right)	0.7	2.7	4.4	0.3	-2.1	-1.6	-1.2	-1.9	-1.8	-1.9	-1.9	-1.9	-1.9	1.5	-0.8	-1.7	-1.9	-1.6	-1.8	-1.7	-1.6	1.7	-1.3	-1.9	0.7
Trunk fat-free mass	0.4	2.3	4.4	-0.0	-0.8	-0.3	-1.8	-1.7	-1.5	-2.0	-1.8	-1.8	-0.3	-2.1	-2.1	-1.9	-1.4	-1.7	-1.7	-1.4	-2.0	1.7	-0.4	-1.6	0.2
Hip circumference	0.4	1.8	4.4	-0.5	-2.1	-1.3	-1.2	-1.4	-1.2	-1.5	-1.8	-1.5	-0.8	-0.8	-0.9	-1.3	-1.7	-1.4	-1.2	-1.1	-1.3	1.4	-1.2	-1.4	1.5
Time employed in main current job	0.2	0.2	1.1	-0.9	-0.2	0.1	-0.5	-0.2	-0.2	-0.5	0.1	-0.3	-1.1	1.0	0.2	-0.4	-0.2	-0.2	-0.4	-0.2	-0.4	0.2	-0.3	-0.2	0.4
Alcohol intake versus 10 years previously	0.4	0.6	4.7	-2.2	-0.9	0.7	0.9	0.3	0.4	0.8	0.3	0.6	-0.7	-0.2	-0.1	0.9	-0.3	0.4	0.4	0.2	0.9	-0.4	-1.3	0.4	-0.8
Father’s age at death	0.9	1.2	2.2	-1.5	0.6	0.4	1.3	1.4	1.3	1.2	1.2	1.4	0.9	-0.7	-0.3	1.3	1.0	1.4	1.2	1.3	1.0	-1.4	0.0	1.4	0.1
Worrier / anxious feelings	1.2	2.3	5.9	0.4	-2.4	-1.7	-1.7	-1.6	-1.5	-1.2	-1.3	-1.8	-2.4	-0.1	-0.5	-1.2	-1.8	-1.5	-1.5	-1.6	-1.3	1.6	-1.4	-1.5	-1.2
Frequency of tiredness / lethargy in last 2 weeks	1.5	2.4	4.3	-0.6	-1.1	-0.6	-2.1	-1.7	-1.8	-1.9	-1.7	-1.7	-1.6	0.9	-1.5	-1.8	-1.3	-1.5	-1.8	-1.8	-1.8	1.5	-0.6	-1.8	-1.6
Falls in the last year	0.7	1.0	3.8	-1.5	0.4	-0.9	1.0	0.9	1.1	0.8	0.8	0.7	1.0	-1.7	-0.2	0.8	0.6	0.7	1.0	1.2	0.7	-0.7	0.4	1.0	1.9
Hair/balding pattern: Pattern 3	1.2	1.8	3.6	0.6	-1.4	-1.1	-1.9	-1.5	-1.6	-1.5	-0.9	-1.6	-0.7	-0.7	-1.2	-1.4	-1.6	-1.4	-1.5	-1.6	-1.5	1.4	-1.3	-1.6	-0.4
Number of live births	0.2	0.2	0.7	-0.5	-0.0	-0.8	0.5	0.3	0.2	0.7	0.1	0.2	-0.7	0.8	0.4	0.7	0.3	0.4	0.3	0.4	0.6	-0.4	-0.0	0.2	-0.7
Forced expiratory volume in 1-second (FEV1)	1.0	3.5	8.1	-1.1	-1.8	0.2	-2.9	-1.9	-2.0	-2.2	-1.9	-2.0	-1.2	-1.3	-1.9	-2.3	-1.1	-1.9	-2.2	-2.2	-2.4	1.9	0.0	-1.9	-2.2
Pulse rate	5.4	9.1	15.9	0.2	-0.8	-0.6	-3.0	-3.5	-3.7	-3.8	-2.3	-3.1	-3.0	2.3	-2.1	-3.7	-2.7	-3.2	-3.9	-3.8	-3.8	3.2	-1.1	-3.6	-4.0
Happiness	0.4	0.5	4.6	2.1	1.3	-0.7	0.5	-0.4	-0.2	-0.5	-0.4	-0.5	0.3	-0.8	-0.3	-0.5	-0.3	-0.6	-0.2	-0.3	-0.5	0.6	0.4	-0.3	0.1
Noisy workplace	1.2	1.5	2.7	0.3	1.1	-0.6	1.4	1.3	1.3	1.4	0.8	1.0	1.1	-0.9	1.6	1.4	1.5	1.1	1.3	1.5	1.3	-1.2	1.4	1.3	1.1
Qualifications: A levels/AS levels or equivalent	0.0	0.1	0.8	0.2	-0.0	-0.6	-0.5	0.0	-0.1	-0.0	0.4	-0.1	0.2	-0.9	-0.1	-0.0	0.2	0.2	-0.2	-0.0	-0.1	-0.2	0.1	-0.0	0.6
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	2.8	-0.1	-0.2	0.5	0.6	0.9	0.8	1.1	1.2	1.2	0.4	0.9	1.7	0.9	0.8	0.9	0.9	0.7	1.1	-0.9	0.2	0.9	-0.5
Mouth/teeth dental problems: Dentures	1.4	2.3	5.8	-1.2	-2.4	-1.1	-0.4	-1.4	-1.5	-1.5	-1.6	-1.5	-2.2	0.8	-1.6	-1.4	-1.7	-1.2	-1.7	-1.3	-1.5	1.2	-2.2	-1.5	-0.8
Asthma	0.9	1.8	4.3	-1.7	-1.8	-0.6	-1.3	-1.2	-1.3	-1.4	-0.9	-1.3	-2.1	0.6	-1.2	-1.3	-1.6	-1.1	-1.4	-1.2	-1.4	1.1	-1.7	-1.3	0.1
Medication: Ibuprofen (e.g. Nurofen)	1.7	2.2	4.4	1.0	0.0	-2.1	-0.9	-1.6	-1.1	-1.3	-1.3	-1.5	-2.0	1.5	-0.8	-1.5	-1.5	-2.1	-1.3	-1.5	-1.5	2.1	-0.4	-1.4	-1.9
Medication: Cholesterol lowering	0.8	1.3	3.0	-0.2	-1.0	0.4	-1.6	-1.1	-1.3	-1.1	-1.5	-0.9	-1.3	1.2	-0.7	-1.0	-0.9	-1.0	-1.3	-1.3	-1.0	1.0	-0.6	-1.2	-1.7
Depression (self-reported)	0.7	0.9	13.2	-0.7	-0.7	0.0	-0.2	0.2	0.1	0.1	0.5	0.1	1.4	-3.6	-0.1	0.2	-0.6	0.4	0.2	0.3	0.1	-0.4	-1.2	0.1	0.9
Medication: Lansoprazole	0.3	0.4	1.8	-1.3	1.1	0.3	0.7	0.3	0.1	0.6	0.5	0.5	-0.3	0.5	1.2	0.7	0.4	0.5	0.3	0.1	0.8	-0.5	0.1	0.3	0.1
Prospective memory result	1.3	1.6	2.5	-0.3	1.4	1.6	1.0	1.4	1.3	1.1	1.5	1.5	1.4	1.2	0.8	0.9	1.5	1.6	1.2	1.4	1.0	-1.5	1.1	1.4	-0.7
Lung cancer (father)	0.2	0.2	1.9	-0.4	-1.4	-0.6	-0.5	-0.1	-0.2	0.1	-0.2	0.1	0.4	-1.2	0.0	0.2	-0.2	-0.0	-0.0	0.1	0.2	0.0	-0.6	-0.2	-0.0
Illnesses of mother	1.0	1.3	8.5	-2.9	-0.0	-0.7	-0.1	1.2	0.9	1.0	1.2	1.2	1.3	-0.2	0.9	1.1	0.9	1.2	1.0	1.3	1.1	-1.3	-0.4	1.0	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.9	5.9	9.3	-0.9	-1.9	-0.3	-2.7	-2.8	-2.7	-2.6	-2.6	-2.7	-2.6	-0.4	-2.2	-2.8	-2.0	-2.9	-2.8	-3.0	-2.8	2.9	-0.2	-2.7	-3.0
Pulse wave Arterial Stiffness index	0.4	0.5	3.4	-0.6	0.1	0.0	1.0	0.6	0.7	1.0	0.1	0.5	-0.1	0.4	1.9	0.9	0.3	0.6	0.8	0.8	0.8	-0.6	-0.3	0.6	0.1
Impedance of arm (left)	0.2	1.0	5.1	-0.7	-2.3	-1.0	-1.2	-0.8	-1.2	-0.2	-0.1	-0.5	-1.7	0.3	-0.4	-0.0	-0.9	-0.5	-0.9	-1.1	-0.1	0.5	-1.3	-1.0	-1.9
Arm fat mass (right)	0.6	2.6	4.4	0.2	-1.6	-1.4	-1.2	-1.9	-1.8	-2.0	-2.1	-2.0	-1.5	0.7	-0.9	-1.9	-1.8	-1.8	-1.8	-1.7	-1.8	1.8	-0.9	-1.9	0.8
Trunk predicted mass	0.4	2.4	4.5	-0.0	-0.8	-0.3	-1.7	-1.7	-1.5	-2.0	-1.8	-1.9	-0.3	-2.1	-2.1	-2.0	-1.4	-1.7	-1.7	-1.4	-2.0	1.7	-0.4	-1.6	0.3
Standing height	0.9	8.8	14.7	-0.9	-2.9	-1.1	-3.8	-3.4	-3.5	-3.2	-2.8	-3.3	-2.0	-3.5	-3.6	-2.9	-2.8	-3.2	-3.5	-3.5	-3.1	3.2	-1.4	-3.5	-1.1
Length of working week for main job	0.6	0.7	4.4	0.5	2.1	-0.2	1.2	0.6	0.6	0.6	0.1	0.6	0.1	1.4	0.7	0.6	1.1	0.6	0.6	0.4	0.6	-0.6	1.2	0.7	-0.2
Exposure to tobacco smoke at home	0.3	0.4	2.8	-1.0	0.7	-1.7	0.5	0.2	0.2	0.3	-0.4	0.1	-0.2	0.8	-0.2	0.1	0.3	0.1	0.2	0.2	0.2	-0.1	0.0	0.2	-1.6
Breastfed as a baby	1.4	1.7	3.9	1.2	-0.2	-0.6	-2.0	-1.5	-1.4	-1.3	-2.0	-1.7	-1.2	-0.5	-0.8	-1.1	-1.2	-1.6	-1.2	-1.5	-1.2	1.6	-0.7	-1.4	1.3
Tense / ‘highly strung’	1.8	3.0	5.3	0.4	-0.7	-1.5	-2.3	-1.9	-1.9	-2.2	-1.4	-2.0	-0.9	-0.8	-2.2	-2.2	-1.6	-1.9	-2.0	-1.9	-2.3	1.9	-0.4	-1.9	-1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	4.3	0.2	-1.3	-1.0	-1.5	-1.4	-1.6	-1.6	-1.0	-1.5	-0.2	-2.1	-0.5	-1.6	-1.6	-1.3	-1.6	-1.8	-1.7	1.3	-1.2	-1.4	-0.4
Hair/balding pattern: Pattern 4	0.5	1.2	4.0	1.2	0.4	0.0	-0.5	-1.0	-0.8	-1.5	-0.8	-1.1	-1.0	2.0	1.5	-1.5	-0.8	-1.1	-1.0	-0.9	-1.5	1.1	0.2	-0.9	1.0
Birth weight of first child	0.4	0.7	2.7	0.8	0.7	0.8	1.0	0.5	0.6	0.7	0.8	0.8	0.9	-1.1	-0.2	0.9	0.7	0.6	0.8	0.9	0.8	-0.6	1.0	0.5	1.7
Peak expiratory flow (PEF)	3.1	7.2	12.9	-1.5	-2.2	0.1	-2.8	-2.8	-3.0	-3.0	-3.0	-2.9	-3.3	1.1	-2.8	-3.1	-1.8	-2.7	-3.3	-3.6	-3.2	2.7	-0.8	-2.8	-3.4
Pulse wave reflection index	2.8	3.4	8.1	-0.7	-0.4	1.1	2.7	2.2	2.2	2.2	1.4	2.0	1.2	-0.4	2.8	2.0	0.7	2.1	2.3	2.6	1.9	-2.1	-1.2	2.1	0.9
Ever highly irritable/argumentative for 2 days	0.3	0.3	3.2	0.4	1.0	-1.8	-0.4	-0.2	-0.2	0.1	-0.6	-0.4	-0.7	0.0	-0.7	0.1	0.0	-0.3	-0.2	-0.3	0.1	0.3	0.4	-0.2	0.4
Loud music exposure frequency	0.8	0.9	9.9	3.1	0.1	-0.4	-0.9	-0.8	-0.6	-0.7	-0.5	-0.9	-0.3	0.1	-0.4	-0.7	-1.1	-0.9	-0.6	-0.4	-0.7	0.9	-0.7	-0.7	0.4
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	1.4	-0.5	0.7	0.3	0.3	0.9	1.0	0.2	1.2	1.0	0.9	0.4	0.5	0.1	0.3	0.9	0.7	0.9	0.2	-0.8	-0.3	0.9	0.1
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	3.5	-1.9	-0.7	-1.1	-0.6	-0.0	0.1	0.1	-0.3	-0.0	-0.6	0.5	-1.0	0.1	-0.1	-0.1	-0.1	0.1	-0.0	0.1	-0.5	0.0	-0.5
Blood clot in the leg (DVT)	0.2	0.2	1.1	-0.9	0.2	0.7	-0.1	0.2	-0.1	0.1	-0.5	0.1	0.2	-1.1	-0.9	0.2	0.1	0.4	0.0	0.5	0.1	-0.4	-0.2	0.0	-0.5
Medication: Paracetamol	1.4	2.3	3.9	-0.5	-1.0	-1.0	-1.8	-1.6	-1.4	-1.7	-1.5	-1.4	-1.7	0.9	-0.1	-1.8	-2.0	-1.7	-1.5	-1.4	-1.7	1.7	-1.7	-1.5	-1.9
Headache pain in last month	0.3	0.6	5.7	-1.4	-0.2	0.4	-1.2	-0.3	-0.1	-0.4	-0.3	-0.1	-0.7	1.1	-0.2	-0.6	-0.2	-0.4	-0.3	-0.3	-0.5	0.4	0.1	-0.2	-2.4
Medication for cholesterol, blood pressure or diabetes	1.1	1.9	3.8	-0.5	0.1	0.3	1.7	1.5	1.7	1.5	1.9	1.3	1.3	-1.7	1.4	1.4	0.8	1.3	1.6	1.7	1.3	-1.3	-0.2	1.6	1.4
Glaucoma (self-reported)	0.4	0.5	1.5	-1.0	0.0	-0.1	-0.9	-0.6	-0.5	-1.2	-0.9	-0.8	0.2	-0.2	0.2	-1.2	-0.4	-0.5	-0.6	-0.4	-1.2	0.5	0.1	-0.5	0.6
Gout (self-reported)	0.3	0.5	3.1	-0.1	-0.7	0.4	-0.8	0.4	-0.0	0.4	0.2	0.4	0.7	-1.2	-0.6	0.7	0.1	0.8	0.1	0.3	0.7	-0.8	-0.7	0.2	1.8
Hypothyroidism/myxoedema (self-reported)	3.0	5.8	32.3	-0.5	-2.2	0.4	2.0	2.3	2.6	2.5	1.5	2.3	2.9	-5.7	1.1	2.6	0.6	2.1	2.7	2.7	2.6	-2.1	-1.6	2.4	2.1
Medication: Amlodipine	0.8	1.1	4.1	-1.7	-0.3	-0.4	-0.8	-1.0	-1.0	-0.4	-1.4	-0.9	-2.0	1.1	-1.5	-0.3	-0.7	-0.9	-0.9	-1.0	-0.4	0.9	-0.2	-1.0	-1.7
Medication: Ventolin 100micrograms inhaler	0.4	0.6	4.4	-2.1	-0.8	-0.5	-1.1	-0.6	-0.8	-0.7	-0.2	-0.5	-0.8	0.2	-0.1	-0.5	-0.5	-0.4	-0.8	-0.7	-0.5	0.4	-0.7	-0.7	0.2
Birth weight	0.5	1.1	6.0	-0.2	1.4	0.7	-0.3	0.6	0.7	0.7	0.7	0.5	1.6	-2.5	0.5	0.9	0.8	0.6	0.8	0.7	0.9	-0.5	1.0	0.6	2.1
Chronic bronchitis/emphysema (mother)	0.7	0.8	2.2	0.9	0.2	1.5	1.4	0.8	0.8	1.0	1.4	0.9	0.5	-0.1	1.1	1.0	0.2	0.8	0.8	0.7	1.1	-0.8	-0.6	0.8	0.3
High blood pressure (siblings)	0.6	0.8	3.3	1.8	0.1	-1.8	-0.7	-0.8	-0.6	-0.8	-0.9	-0.9	-0.8	0.7	0.1	-0.9	-0.2	-0.9	-0.7	-0.9	-0.7	0.9	0.9	-0.7	0.9
Forced vital capacity (FVC), Best measure	2.0	7.4	11.8	-0.5	-2.1	-0.4	-3.1	-3.2	-3.2	-3.0	-2.8	-3.2	-2.8	-1.0	-2.2	-3.1	-2.5	-3.3	-3.2	-3.4	-3.2	3.3	-0.6	-3.2	-2.5
Body fat percentage	0.5	1.9	3.3	0.2	-1.7	-1.4	-0.7	-1.6	-1.6	-1.6	-1.8	-1.6	-1.5	1.2	-0.3	-1.4	-1.6	-1.4	-1.5	-1.5	-1.3	1.5	-1.0	-1.6	1.1
Leg fat percentage (right)	0.2	0.8	1.6	0.0	-1.0	-0.9	0.4	-0.9	-0.8	-1.0	-1.2	-1.0	-0.8	1.0	0.4	-0.9	-1.3	-0.8	-0.8	-0.8	-0.8	0.9	-1.1	-0.9	1.2
Arm fat-free mass (right)	0.2	1.1	4.0	-0.0	0.0	-0.3	-0.8	-1.0	-0.7	-1.4	-1.2	-1.2	0.6	-2.0	-1.3	-1.4	-0.6	-1.1	-1.0	-0.7	-1.4	1.1	0.4	-0.9	1.5
Exposure to tobacco smoke outside home	0.5	0.6	3.9	-0.8	-1.3	-0.3	0.8	-0.0	-0.1	0.2	0.4	0.0	-0.5	-1.7	0.6	0.3	-0.9	-0.0	-0.1	0.1	0.2	0.0	-2.0	-0.1	-1.5
Comparative body size at age 10	0.1	0.3	2.0	0.3	-0.4	0.8	-0.5	-0.3	-0.5	-0.2	0.0	-0.5	0.0	-1.2	0.0	-0.1	-0.9	-0.1	-0.5	-0.4	-0.2	0.1	-1.4	-0.4	-0.4
Number of full brothers	1.2	1.6	4.6	-0.4	1.2	0.5	2.1	1.3	1.3	1.6	0.9	1.4	0.1	0.8	0.5	1.7	1.7	1.3	1.3	0.8	1.7	-1.3	1.3	1.3	0.8
Worry too long after embarrassment	3.2	5.4	10.8	0.4	-2.3	-1.9	-2.8	-2.3	-2.0	-2.4	-2.8	-2.6	-1.4	-2.3	-2.7	-2.6	-3.3	-2.3	-2.2	-1.9	-2.7	2.3	-2.8	-2.2	-1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	9.9	-1.0	-0.7	0.2	-0.1	-0.0	-0.1	0.1	-0.6	-0.2	0.8	-3.1	0.1	0.1	-0.1	0.0	0.1	-0.0	-0.0	-0.0	0.2	-0.1	-0.4
Wheeze or whistling in the chest in last year	2.3	4.2	9.1	-0.9	-2.8	-1.2	-1.9	-2.2	-2.2	-2.1	-2.0	-2.3	-2.2	-0.6	-1.5	-2.0	-2.9	-2.0	-2.1	-1.9	-2.1	2.0	-3.0	-2.2	-0.5
Number of children fathered	0.3	0.4	2.3	-0.7	0.2	-0.9	-0.7	0.2	0.3	0.5	0.1	0.2	0.5	-1.5	0.5	0.6	0.2	0.0	0.4	0.3	0.7	-0.0	-0.0	0.2	1.2
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	2.7	-0.6	0.2	1.1	-0.2	-1.4	-1.3	-1.3	-1.1	-1.3	-1.6	1.2	-1.6	-1.3	-1.1	-1.3	-1.3	-1.4	-1.4	1.3	-0.3	-1.3	-0.5
Age at first live birth	0.1	0.2	1.5	0.2	-0.1	0.4	-1.2	-0.1	-0.0	-0.3	0.1	-0.0	0.2	0.6	-0.6	-0.3	0.4	-0.1	-0.2	-0.1	-0.4	0.1	1.0	-0.0	-0.4
Pulse wave peak to peak time	0.7	0.9	4.7	0.6	-0.6	-0.1	-1.3	-0.9	-1.0	-1.1	-0.3	-0.8	-0.2	-0.9	-2.2	-1.1	-0.6	-0.9	-1.0	-1.1	-0.9	0.9	-0.1	-0.9	-0.2
Health satisfaction	0.8	1.1	1.7	0.0	-0.3	-1.2	-0.8	-1.3	-1.3	-1.3	-1.1	-1.2	-0.4	-1.2	-0.8	-1.1	-0.9	-1.1	-1.3	-1.1	-1.2	1.1	-0.0	-1.3	-0.8
Shortness of breath walking on level ground	0.3	0.4	2.1	-0.4	1.3	0.2	1.1	0.0	-0.0	0.2	-0.2	0.1	-0.1	1.0	-0.6	0.3	0.7	0.3	0.0	-0.1	0.2	-0.3	1.4	0.0	0.5
Qualifications: College or University degree	0.6	1.8	11.2	0.7	0.9	0.5	-0.3	1.0	1.2	0.6	1.4	1.0	3.3	-3.1	0.2	0.5	1.2	1.0	1.1	1.2	0.5	-0.9	1.4	1.1	1.3
Eye problems/disorders: None of the above	0.5	0.6	2.5	-0.0	-1.2	0.5	0.6	-0.6	-0.6	-0.8	-0.3	-0.5	-0.5	0.9	0.3	-0.9	-0.8	-0.6	-0.6	-0.7	-0.9	0.6	-0.8	-0.6	-1.6
Mouth/teeth dental problems: Loose teeth	0.6	0.7	3.5	-0.1	1.9	-0.3	0.3	0.7	0.6	0.4	0.4	0.5	1.1	0.9	1.4	0.4	1.1	0.7	0.7	0.7	0.4	-0.7	1.3	0.7	0.6
Emphysema/chronic bronchitis	0.8	0.8	2.8	-0.8	-1.4	-0.1	-0.6	-0.9	-0.8	-0.8	-1.2	-0.8	-0.9	0.1	-0.8	-0.8	-1.5	-0.9	-0.8	-0.8	-0.7	0.9	-1.7	-0.9	0.1
Medication for pain relief, constipation, heartburn	1.2	2.1	4.1	0.3	0.6	1.7	2.0	1.5	1.2	1.3	1.7	1.4	2.0	-1.4	0.6	1.4	1.5	1.7	1.3	1.4	1.3	-1.7	1.0	1.4	1.9
Neck or shoulder pain in last month	1.5	2.1	6.0	0.9	0.5	-0.7	-0.6	-1.7	-1.7	-1.1	-1.4	-1.6	-2.4	2.0	-0.3	-1.1	-0.9	-1.6	-1.6	-2.0	-1.2	1.6	0.4	-1.6	-2.1
Medication: Blood pressure	1.0	1.7	4.3	1.1	0.9	-1.1	-1.8	-1.3	-1.5	-1.5	-1.8	-1.1	-0.9	2.1	-0.9	-1.3	-0.5	-1.1	-1.4	-1.5	-1.3	1.1	0.7	-1.3	-1.2
Angina (self-reported)	0.5	0.6	2.5	1.0	0.3	1.0	-0.6	-0.7	-0.5	-0.7	-1.6	-0.8	-0.9	1.6	0.2	-0.8	-0.3	-0.8	-0.5	-0.5	-0.7	0.8	0.3	-0.7	-0.4
Migraine (self-reported)	0.7	0.9	2.5	-1.4	-0.9	1.1	0.2	1.0	1.2	1.0	1.1	1.1	0.6	-1.6	0.2	0.9	0.3	0.7	1.0	1.3	0.9	-0.8	-0.7	1.1	0.7
Medication: Ibuprofen	1.9	2.3	5.0	0.4	-0.1	-2.2	-1.3	-1.8	-1.5	-1.5	-1.2	-1.6	-2.1	1.2	-0.4	-1.5	-1.7	-2.1	-1.5	-1.7	-1.4	2.1	-0.7	-1.6	-1.2
Medication: Allopurinol	1.3	1.7	4.9	0.7	-2.2	-0.4	-1.9	-1.1	-1.6	-1.1	-1.5	-1.1	-0.8	-1.5	-1.7	-0.7	-1.5	-0.6	-1.5	-1.4	-0.8	0.6	-1.9	-1.4	0.6
Medication: Omeprazole	0.3	0.4	1.6	-0.3	0.2	-0.3	1.3	0.7	0.7	0.5	0.5	0.5	0.6	0.0	0.4	0.4	0.7	0.8	0.6	0.7	0.4	-0.8	0.6	0.7	0.7
Medication: Seretide 50 evohaler	0.7	0.8	2.6	-1.6	-0.2	0.6	0.4	1.0	0.9	1.1	0.3	0.8	0.3	-0.3	0.5	1.0	1.4	1.1	0.8	0.7	0.9	-1.1	0.9	1.0	0.6
Mean time to correctly identify matches	0.2	0.3	2.7	0.6	-0.9	0.2	-0.8	-0.0	-0.3	0.1	-0.4	0.1	-0.4	1.6	0.4	0.2	-0.4	0.3	-0.2	-0.2	0.2	-0.3	-0.9	-0.1	-0.8
Heart disease (mother)	1.9	2.3	10.0	3.2	-0.8	0.7	-1.2	-1.6	-1.5	-1.6	-1.6	-1.7	-1.0	-1.2	-0.7	-1.6	-1.7	-1.6	-1.5	-1.7	-1.5	1.7	-0.8	-1.6	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.9	0.7	0.1	-1.4	-0.5	-0.5	-0.4	-0.4	-0.4	-0.6	0.6	-0.9	0.1	-0.4	-0.5	-0.5	-0.3	-0.6	-0.4	0.5	-0.3	-0.5	-0.1
Whole body fat mass	0.7	3.0	5.3	0.0	-1.9	-1.4	-1.2	-2.1	-2.0	-2.1	-2.3	-2.1	-1.6	0.5	-1.1	-1.9	-2.0	-1.9	-2.0	-1.9	-1.8	1.9	-1.1	-2.1	1.0
Leg fat mass (right)	0.4	1.6	3.5	0.2	-1.1	-1.1	-0.5	-1.5	-1.3	-1.6	-1.9	-1.6	-1.0	0.7	-0.4	-1.5	-1.4	-1.4	-1.3	-1.2	-1.4	1.4	-0.7	-1.4	1.4
Arm predicted mass (right)	0.2	1.0	3.5	-0.1	0.0	-0.1	-0.8	-0.9	-0.7	-1.4	-1.1	-1.1	0.7	-1.9	-1.3	-1.4	-0.5	-1.0	-0.9	-0.7	-1.4	1.0	0.5	-0.8	1.3
Pulse rate, automated reading	5.3	17.0	27.6	0.7	-1.1	-2.4	-4.7	-4.7	-4.9	-5.0	-4.4	-4.5	-5.1	4.7	-2.9	-4.7	-3.3	-4.5	-5.0	-5.2	-4.8	4.5	-0.7	-4.7	-2.4
Alcohol intake frequency.	2.4	5.5	9.3	-0.4	1.6	2.3	2.3	2.6	2.8	2.5	2.3	2.8	1.8	0.8	3.0	2.5	2.5	2.6	2.8	2.5	2.6	-2.5	1.4	2.8	1.7
Comparative height size at age 10	0.2	1.0	8.1	-1.2	-0.7	0.2	-1.4	-0.8	-0.8	-0.8	-0.4	-0.8	0.2	-2.9	-1.1	-0.7	-0.5	-0.8	-0.9	-0.7	-0.7	0.8	-0.2	-0.8	0.7
Number of full sisters	0.3	0.4	2.9	0.6	0.1	-1.7	0.6	-0.2	-0.1	0.3	-0.7	-0.3	-1.1	1.0	0.8	0.4	0.2	-0.4	-0.0	-0.2	0.3	0.4	0.6	-0.2	0.8
Suffer from ‘nerves’	4.1	6.4	13.6	1.0	-2.3	-1.8	-3.7	-2.9	-2.9	-2.6	-2.8	-3.0	-2.6	0.3	-1.1	-2.5	-2.8	-2.8	-2.8	-2.9	-2.8	2.9	-1.6	-3.0	-2.0
Overall health rating	2.1	4.5	7.7	-0.2	-1.6	-1.9	-0.9	-2.5	-2.5	-2.6	-2.3	-2.5	-2.8	0.9	-1.5	-2.4	-2.4	-2.2	-2.6	-2.6	-2.5	2.2	-1.6	-2.5	-0.8
Chest pain or discomfort	1.1	1.6	6.4	-0.4	-0.6	-0.8	-2.5	-1.6	-1.4	-1.0	-1.7	-1.4	-1.4	-0.2	-1.5	-0.9	-1.1	-1.6	-1.2	-1.3	-0.9	1.6	0.4	-1.5	-0.2
Had major operations	0.6	0.6	4.8	0.2	-1.6	-1.1	-0.2	0.3	0.4	0.4	-0.6	0.2	-0.1	-2.2	-0.8	0.4	-0.5	0.2	0.4	0.4	0.5	-0.2	-1.4	0.3	0.9
Age at last live birth	0.3	0.5	2.0	-0.1	0.6	0.6	0.4	0.7	0.8	0.8	0.6	0.7	0.6	0.7	0.8	0.5	1.0	0.6	0.8	0.8	0.5	-0.6	1.4	0.8	-0.3
Family relationship satisfaction	0.7	0.9	5.7	2.3	0.1	-0.7	0.1	-0.7	-0.7	-0.7	-1.0	-0.8	0.2	-2.4	-0.7	-0.5	-0.8	-0.6	-0.6	-0.7	-0.4	0.6	-0.7	-0.7	0.7
Leg pain on walking	0.3	0.4	3.8	-1.9	-1.1	0.5	0.6	0.1	0.3	0.3	0.1	0.2	-0.7	0.7	0.4	0.3	0.0	0.1	0.1	0.3	0.4	-0.1	-0.3	0.2	1.2
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	4.9	-0.9	-1.9	0.1	0.9	-0.1	-0.0	0.1	-0.0	-0.1	-0.8	-1.0	-1.3	-0.1	-1.2	-0.4	-0.0	-0.3	-0.1	0.4	-2.2	-0.1	-1.9
Commuting to job workplace: Car/motor vehicle	0.2	0.3	1.8	-1.4	1.1	-0.6	0.7	-0.1	-0.0	-0.0	0.1	-0.0	-0.1	-0.0	-0.2	-0.0	0.5	-0.1	-0.1	-0.3	-0.1	0.1	1.2	-0.0	-0.5
Illness, injury, bereavement, stress in last 2 years	0.4	0.4	2.8	0.5	-0.1	0.6	-0.5	-0.6	-1.0	-0.5	-0.7	-0.7	-0.1	-0.6	-1.7	-0.4	-0.3	-0.6	-0.9	-0.8	-0.5	0.5	-0.1	-0.8	-0.3
Medication: Aspirin	1.3	1.7	3.3	0.3	-1.4	-0.2	-1.8	-1.4	-1.4	-1.1	-1.8	-1.3	-1.5	0.6	-0.2	-1.1	-1.6	-1.3	-1.3	-1.4	-1.1	1.4	-1.3	-1.4	-1.8
Supplements: Vitamin C	0.6	0.7	3.8	0.3	1.8	0.0	-0.6	0.6	0.4	0.5	1.2	0.6	0.9	0.2	-0.3	0.6	1.6	0.7	0.6	0.5	0.6	-0.7	2.0	0.6	-0.2
Knee pain experienced in last month	0.3	0.5	3.1	-0.8	-1.4	0.6	0.2	0.0	0.2	-0.5	0.1	0.0	0.6	-1.2	0.4	-0.7	-0.8	-0.1	-0.1	0.4	-0.5	0.1	-1.8	0.0	-0.2
Hypertension (Self-reported)	0.5	1.5	9.3	-1.1	-2.0	-0.5	-0.8	-0.7	-0.8	-0.8	-1.2	-0.5	-1.7	1.7	-0.6	-0.7	-1.9	-0.5	-0.9	-0.7	-0.6	0.5	-3.1	-0.8	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	3.5	-1.5	1.1	-0.4	-0.0	-0.4	-0.3	-0.7	1.0	-0.2	-0.3	1.9	0.7	-0.7	0.0	-0.3	-0.5	-0.4	-0.7	0.3	0.7	-0.4	-0.8
Illnesses of father: Heart disease	0.2	0.3	0.8	-0.4	-0.9	0.7	-0.6	-0.2	-0.1	-0.6	0.4	-0.0	0.1	-0.7	-0.9	-0.6	-0.7	-0.2	-0.3	0.3	-0.5	0.2	-0.9	-0.2	0.4
Illnesses of siblings: Diabetes	0.2	0.3	1.5	0.9	0.4	-1.1	-0.6	-0.0	-0.1	0.2	0.0	-0.1	-0.2	0.9	0.8	0.2	0.2	0.0	0.0	-0.2	0.2	-0.0	0.5	-0.1	-1.2
Smoking status: Previous	0.7	1.1	2.6	1.0	1.6	0.1	0.7	1.1	1.2	1.0	0.7	0.8	1.2	0.1	1.0	0.8	1.4	1.0	1.2	1.1	0.8	-1.0	1.4	1.2	1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.5	1.4	-0.6	-1.2	0.1	-1.2	-0.8	-0.5	-0.7	-0.5	-0.6	-0.5	-0.9	-1.0	-0.8	-0.6	-0.9	-0.6	-0.7	-0.7	0.9	0.1	-0.6	-0.0
Whole body fat-free mass	0.4	2.0	3.8	0.1	-0.7	-0.6	-1.6	-1.6	-1.4	-1.9	-1.7	-1.8	-0.3	-1.5	-1.9	-1.9	-1.2	-1.6	-1.6	-1.4	-1.9	1.6	-0.1	-1.5	0.6
Leg fat-free mass (right)	0.4	2.0	3.7	0.1	-0.6	-1.2	-1.9	-1.6	-1.4	-1.9	-1.6	-1.8	-0.7	-0.2	-1.9	-1.9	-1.0	-1.6	-1.6	-1.5	-1.9	1.6	0.4	-1.5	0.8
Arm fat percentage (left)	0.4	1.5	3.2	0.3	-1.8	-1.2	-0.7	-1.4	-1.3	-1.3	-1.4	-1.4	-1.4	1.2	-0.4	-1.2	-1.5	-1.1	-1.3	-1.3	-1.1	1.2	-1.0	-1.4	0.9
Average weekly red wine intake	1.3	1.9	5.4	-1.9	-0.4	0.1	1.2	1.6	1.5	1.3	1.3	1.5	1.8	-2.3	0.9	1.3	0.7	1.7	1.5	1.7	1.3	-1.7	-0.7	1.5	0.2
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.9	0.8	-1.3	-0.7	-0.3	0.1	0.0	0.4	0.4	0.2	-0.9	-1.1	-1.4	0.6	-0.4	0.1	-0.0	0.1	0.5	-0.1	-1.3	0.1	-1.1
Mood swings	2.1	3.8	6.1	-0.8	-2.5	-1.2	-1.7	-2.0	-2.0	-2.2	-2.0	-2.2	-1.6	-1.2	-2.4	-2.1	-2.4	-2.0	-2.2	-2.0	-2.3	2.0	-2.1	-2.1	-0.9
Loneliness, isolation	0.3	0.4	4.4	1.2	-0.2	-0.2	0.2	0.0	0.1	-0.1	0.1	0.1	1.1	-2.1	0.2	-0.2	-0.7	0.0	0.1	0.1	-0.2	0.0	-1.0	0.0	-0.9
Long-standing illness, disability or infirmity	0.8	1.2	7.1	-2.7	-2.3	1.0	0.4	0.5	0.5	0.5	0.0	0.6	0.0	-2.1	-0.1	0.6	-0.6	0.6	0.3	0.6	0.6	-0.5	-2.1	0.5	0.4
Ever had bowel cancer screening	0.3	0.3	3.0	-0.5	0.6	1.7	0.1	-0.0	-0.1	-0.2	-0.6	0.1	0.2	-1.0	-0.4	-0.1	-0.5	0.2	0.0	-0.1	-0.0	-0.1	-0.9	-0.1	0.3
Diabetes diagnosed by doctor	0.6	1.0	1.9	-0.7	0.6	-0.5	0.2	1.2	1.2	1.0	1.3	1.4	1.1	1.1	0.1	1.0	1.0	1.2	1.1	1.2	1.2	-1.2	-0.0	1.2	0.5
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	4.9	-1.1	0.1	2.2	0.6	1.2	1.1	1.6	1.2	1.2	-0.2	0.5	0.3	1.6	0.7	1.3	1.1	1.0	1.6	-1.3	-0.8	1.1	0.1
Friendships satisfaction	0.8	1.0	5.2	1.8	0.3	-0.6	-0.8	-0.8	-0.8	-1.1	-1.1	-0.9	0.9	-2.3	-0.5	-1.1	-0.9	-0.7	-0.8	-0.8	-1.1	0.8	-0.6	-0.8	-0.3
Qualifications: nursing, teaching	0.4	0.7	7.0	0.7	-1.5	-0.2	-0.4	0.1	0.2	-0.5	0.2	0.3	1.4	-2.6	-0.2	-0.6	-0.7	0.2	-0.1	0.3	-0.3	-0.1	-1.0	0.1	0.4
Commuting to job workplace: Walk	0.6	0.7	4.5	0.2	1.8	-0.1	0.6	0.6	0.8	0.7	0.6	0.6	0.1	2.1	0.1	0.7	0.6	0.3	0.8	0.8	0.6	-0.3	1.0	0.7	1.0
Eye problems/disorders: Cataract	0.4	0.5	2.3	1.0	0.5	-0.3	-0.1	0.7	0.6	0.6	0.6	0.4	0.7	-0.2	0.2	0.6	1.1	0.7	0.6	0.4	0.5	-0.7	1.1	0.7	1.5
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	1.2	0.1	0.4	0.5	-0.3	0.0	-0.2	0.0	0.5	0.2	0.4	-1.1	-0.2	-0.1	-0.2	0.1	-0.0	0.1	-0.0	-0.1	-0.5	-0.1	-1.0
Medication for cholesterol	0.3	0.5	3.3	-0.3	-0.3	0.1	-0.3	0.8	0.8	0.2	1.0	0.8	1.8	-1.3	0.8	0.2	0.5	0.5	0.8	0.7	0.2	-0.5	0.4	0.8	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	3.5	-1.9	0.1	-0.9	-0.1	0.5	0.4	0.7	-0.1	0.5	-0.6	0.3	-0.7	0.7	-0.2	0.5	0.3	0.6	0.7	-0.5	-1.4	0.5	-0.5
Back pain experienced in last month	1.2	1.7	4.6	-1.9	-1.5	-0.4	-1.7	-1.3	-1.2	-0.9	-1.4	-1.2	-1.8	0.8	-0.1	-0.8	-1.4	-1.3	-1.1	-1.2	-1.0	1.3	-1.3	-1.3	-2.1
Mineral and other dietary supplements	2.0	2.7	6.9	0.4	1.9	1.1	1.8	1.7	1.6	1.2	1.8	1.8	2.0	0.1	2.1	1.2	2.5	1.6	1.5	1.5	1.3	-1.6	2.6	1.7	0.9
Breast cancer (self-reported)	1.3	1.5	5.4	-0.8	-1.5	-1.2	-2.3	-1.1	-1.3	-1.0	-1.5	-1.2	-1.3	-0.8	-1.5	-0.8	-1.2	-1.1	-1.3	-1.4	-0.9	1.1	-1.2	-1.2	0.5
Asthma (self-reported)	0.7	1.4	3.1	-1.6	-1.7	-0.2	-1.5	-1.1	-1.1	-1.3	-0.9	-1.2	-1.8	0.1	-1.2	-1.1	-1.4	-1.0	-1.2	-1.0	-1.2	1.0	-1.5	-1.2	0.3
Osteoporosis (self-reported)	0.9	1.1	5.0	-1.6	-2.1	0.6	-0.5	-0.9	-0.9	-0.5	-0.7	-0.7	-1.3	-1.0	-0.5	-0.5	-1.6	-0.8	-0.9	-0.8	-0.4	0.8	-2.2	-0.9	-0.0
Osteoarthritis (self-reported)	0.8	1.1	3.6	-1.9	0.3	0.6	-1.2	-1.1	-1.1	-1.5	-0.8	-1.1	-0.8	0.3	-0.6	-1.6	-0.5	-0.9	-1.3	-1.1	-1.5	0.9	0.1	-1.1	-0.3
Medication: Aspirin	1.2	1.6	3.0	0.3	-1.6	-0.4	-1.4	-1.3	-1.3	-1.1	-1.7	-1.1	-1.4	0.6	0.1	-1.1	-1.7	-1.3	-1.2	-1.2	-1.1	1.3	-1.7	-1.3	-1.5
Medication: Gliclazide	2.2	2.5	4.4	-0.1	0.9	0.0	1.5	1.8	1.7	1.7	1.9	2.0	1.4	1.6	2.1	1.7	1.8	1.8	1.7	1.9	1.8	-1.8	0.9	1.7	0.5
Illnesses of father: None of the above (group 1)	0.9	1.1	2.2	-0.3	0.2	-1.2	0.9	1.1	1.2	1.3	1.1	1.0	1.4	-1.5	0.8	1.2	1.0	1.0	1.2	1.3	1.2	-1.0	0.2	1.1	0.3
Smoking status: Current	0.2	0.3	1.9	-0.8	-1.2	-1.0	-0.2	0.1	-0.2	-0.1	0.5	0.2	-0.1	-0.2	-0.9	0.1	-0.3	0.2	-0.3	0.1	0.2	-0.2	-1.4	-0.1	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.4	3.1	-0.4	-1.3	-0.7	-0.4	-1.3	-1.1	-0.9	-1.8	-1.2	-1.5	-0.8	-1.4	-1.0	-1.1	-1.5	-1.1	-1.3	-1.0	1.5	-0.4	-1.2	-1.3
Whole body water mass	0.3	1.9	3.3	-0.1	-0.6	-0.7	-1.5	-1.5	-1.3	-1.8	-1.6	-1.7	-0.2	-1.6	-1.8	-1.8	-1.1	-1.5	-1.5	-1.3	-1.8	1.6	0.0	-1.4	0.7
Leg predicted mass (right)	0.3	1.9	3.6	0.1	-0.7	-1.1	-1.9	-1.5	-1.3	-1.9	-1.5	-1.7	-0.6	-0.3	-1.8	-1.8	-0.9	-1.6	-1.5	-1.4	-1.8	1.6	0.4	-1.4	0.9
Arm fat mass (left)	0.6	2.4	4.1	0.3	-1.6	-1.2	-1.1	-1.9	-1.7	-2.0	-2.0	-1.9	-1.2	0.3	-1.0	-1.9	-1.7	-1.7	-1.8	-1.7	-1.8	1.8	-0.8	-1.9	1.0
Number of self-reported non-cancer illnesses	1.7	2.9	6.4	-2.5	-1.8	-0.5	-1.1	-1.7	-1.7	-1.9	-1.8	-1.5	-1.9	-0.8	-1.7	-1.6	-2.2	-1.5	-1.9	-1.7	-1.6	1.5	-2.5	-1.7	-0.4
Average weekly champagne plus white wine intake	0.6	0.8	8.4	1.6	-0.9	0.2	-0.1	0.1	0.0	0.2	0.6	0.2	1.4	-2.9	-1.4	0.4	-0.7	0.2	0.3	0.1	0.4	-0.2	-1.0	0.0	0.3
Miserableness	0.3	0.6	2.7	0.3	-0.7	-0.8	-0.0	-0.7	-0.7	-0.8	-0.7	-0.9	-0.7	-0.7	-1.6	-0.8	-0.4	-0.8	-0.8	-1.1	-0.8	0.8	0.4	-0.7	-0.1
Guilty feelings	0.5	0.7	3.3	0.2	-1.7	-0.2	-0.9	-0.6	-0.6	-1.0	-0.6	-0.8	0.4	-1.8	0.4	-1.1	-0.9	-0.6	-0.6	-0.7	-1.0	0.6	-0.8	-0.6	-0.2
Wears glasses or contact lenses	1.9	2.2	3.9	-0.2	-1.7	0.9	-1.5	-1.5	-1.9	-1.7	-2.0	-1.6	-0.8	-0.8	-1.1	-1.7	-1.5	-1.1	-2.0	-1.5	-1.8	1.1	-1.6	-1.7	-1.1
Ever taken oral contraceptive pill	0.5	0.5	6.6	-2.6	-0.5	0.8	-0.9	-0.4	-0.6	-0.6	-0.1	-0.3	-0.1	-0.8	0.1	-0.4	-0.3	-0.0	-0.5	-0.6	-0.4	0.0	-0.5	-0.5	0.2
Hearing aid user	0.8	1.0	3.0	-1.0	-1.2	0.2	-1.5	-1.0	-1.0	-0.8	-1.1	-0.9	-1.2	-0.4	-1.7	-0.7	-0.8	-1.0	-1.0	-0.9	-0.8	1.0	-0.5	-1.0	-0.6
Mother’s age at death	1.8	2.2	5.8	-1.3	0.5	1.2	1.7	1.5	1.6	1.6	1.8	1.6	1.7	-2.4	1.1	1.6	0.7	1.5	1.6	1.9	1.6	-1.5	-0.3	1.5	1.2
Financial situation satisfaction	0.6	0.8	2.2	0.3	1.5	-0.8	-0.1	-0.9	-1.0	-1.2	-1.2	-0.9	-0.3	1.2	-0.5	-1.1	-0.3	-0.7	-1.0	-0.8	-1.1	0.7	0.5	-0.9	-0.9
Tinnitus: Yes, now most or all of the time	0.5	0.5	2.8	-1.5	0.7	-0.8	0.7	0.7	0.6	0.6	0.2	0.6	-0.6	1.7	0.7	0.7	0.5	0.6	0.6	0.5	0.6	-0.6	0.1	0.6	0.0
Commuting to job workplace: Public transport	0.6	0.7	5.5	2.3	0.4	0.8	-1.3	-0.1	-0.1	-0.5	0.2	-0.2	1.2	-1.8	-0.4	-0.4	-0.1	-0.2	-0.1	0.1	-0.3	0.2	0.4	-0.1	0.9
Eye problems/disorders: Glaucoma	0.9	1.1	2.9	-1.2	-0.2	-0.7	-1.1	-1.1	-1.0	-1.7	-1.4	-1.1	-0.6	0.6	-0.5	-1.6	-0.8	-1.0	-1.1	-0.8	-1.6	1.0	0.1	-1.1	0.6
Medication: Blood pressure	0.4	0.7	3.6	-1.9	-1.2	-0.2	0.0	-0.1	-0.2	0.2	-0.6	-0.1	-1.7	1.5	-1.0	0.1	-0.8	0.0	-0.4	-0.0	0.1	-0.0	-1.9	-0.2	-0.7
Pain type(s) experienced in last month: Hip pain	0.3	0.3	2.3	1.5	-0.3	1.3	0.4	-0.1	-0.0	-0.3	0.3	0.0	0.4	0.2	1.1	-0.5	-0.4	-0.1	-0.1	0.1	-0.4	0.1	-0.6	-0.1	-0.3
Supplements: Fish oil (including cod liver oil)	0.8	1.0	2.4	0.3	-0.9	-1.1	-1.5	-1.1	-1.0	-0.5	-1.4	-1.2	-1.1	-0.5	-1.3	-0.5	-1.6	-1.1	-0.7	-0.9	-0.6	1.1	-1.4	-1.1	-0.5
High cholesterol (Self-reported)	1.0	1.9	4.4	0.2	0.2	-0.5	-0.6	-1.6	-1.6	-1.7	-1.7	-1.3	-1.3	2.1	-0.7	-1.6	-0.8	-1.4	-1.7	-1.7	-1.5	1.4	0.4	-1.6	-1.8
Medication: Bendroflumethiazide	2.7	4.0	6.9	0.5	-2.2	-1.4	-1.7	-2.3	-2.3	-1.8	-2.5	-2.1	-2.4	0.3	-2.2	-1.9	-2.6	-2.0	-2.3	-1.9	-1.9	2.0	-2.4	-2.3	-1.3
Medication: Paracetamol	0.9	1.4	3.2	-0.8	-0.3	-1.2	-1.8	-1.2	-1.1	-1.4	-1.3	-1.1	-1.3	0.6	-0.0	-1.4	-1.4	-1.4	-1.1	-1.1	-1.3	1.4	-1.2	-1.2	-0.8
Medication: Lisinopril	1.2	1.5	4.8	-1.0	1.1	0.3	2.2	1.3	1.1	0.9	1.1	1.6	0.8	2.0	0.8	0.7	1.1	1.5	0.8	1.1	0.8	-1.5	0.1	1.3	-1.7
Medication: Atorvastatin	2.1	2.6	6.9	1.3	-0.8	-0.6	-2.6	-1.8	-1.9	-1.8	-2.0	-1.8	-1.6	1.6	-0.6	-1.8	-1.1	-1.7	-1.8	-1.9	-1.8	1.7	-0.0	-1.8	-0.5
Illnesses of father: High blood pressure	0.3	0.3	2.8	0.6	-0.6	1.7	-0.8	0.1	0.1	-0.2	0.1	0.2	0.1	1.2	0.9	-0.2	-0.1	0.2	0.0	0.0	-0.2	-0.2	-0.0	0.1	0.8
Alcohol drinker status: Never	0.2	0.2	1.6	0.2	-0.0	0.3	-1.1	0.3	0.3	0.0	0.4	0.2	0.4	-0.1	0.6	0.2	0.5	0.2	0.3	0.2	0.3	-0.2	0.2	0.3	1.2
Ever smoked	0.2	0.4	2.5	1.4	1.0	-0.5	-0.1	0.3	0.3	-0.1	0.3	-0.1	1.0	-0.2	-0.1	-0.2	0.6	0.2	0.2	0.5	-0.2	-0.2	0.8	0.3	1.6
Basal metabolic rate	0.4	2.5	4.4	0.2	-0.9	-0.9	-1.8	-1.8	-1.6	-2.1	-1.9	-2.0	-0.6	-1.2	-1.9	-2.0	-1.4	-1.8	-1.8	-1.6	-2.0	1.8	-0.2	-1.8	0.8
Leg fat percentage (left)	0.2	0.9	1.8	0.4	-0.9	-1.0	-0.1	-1.0	-0.9	-1.1	-1.3	-1.0	-0.8	1.3	0.4	-0.9	-1.1	-0.9	-0.9	-0.8	-0.9	0.9	-0.7	-1.0	1.3
Arm fat-free mass (left)	0.4	1.9	3.6	-0.1	-0.4	-1.0	-1.2	-1.6	-1.2	-1.9	-1.8	-1.8	-0.3	-1.6	-1.7	-1.8	-1.2	-1.7	-1.4	-1.3	-1.8	1.7	0.1	-1.5	1.1
Number of operations (self-reported)	0.7	1.0	2.2	-0.2	-0.2	0.3	0.5	1.2	1.4	1.3	0.5	1.0	0.6	-1.5	0.1	1.3	0.7	1.1	1.3	1.3	1.3	-1.1	-0.1	1.3	1.5
Average weekly beer plus cider intake	0.2	0.3	2.2	0.1	0.6	-0.2	0.3	0.2	0.3	0.7	-0.2	-0.1	-0.6	0.2	0.1	0.7	0.4	0.1	0.5	0.6	0.7	-0.1	0.3	0.2	1.5
Irritability	0.9	1.6	8.2	-0.7	0.6	-1.8	-0.8	-1.1	-0.9	-1.1	-1.2	-1.2	-1.1	0.4	-2.9	-1.2	-0.8	-1.3	-1.1	-1.5	-1.2	1.3	-0.0	-1.0	-1.6
Risk taking	0.6	0.9	3.9	-0.8	0.4	-0.4	-1.1	0.8	0.8	0.9	0.2	0.4	0.8	-2.0	-1.1	1.1	0.7	0.8	0.8	0.7	1.0	-0.8	0.1	0.8	1.7
Ever had prostate specific antigen (PSA) test	0.2	0.2	1.9	0.5	-0.1	0.6	-0.5	-0.2	-0.2	-0.2	-0.1	0.0	0.6	-1.4	0.1	-0.2	-0.4	-0.2	-0.2	-0.3	-0.1	0.2	-0.2	-0.2	-0.8
Fractured/broken bones in last 5 years	2.0	2.5	5.2	0.0	-2.3	-1.9	-0.5	-1.7	-1.6	-1.7	-1.4	-1.7	-1.4	-0.6	-0.9	-1.8	-2.2	-1.9	-1.6	-1.7	-1.8	1.9	-1.7	-1.7	-0.6
Age started oral contraceptive pill	0.3	0.4	4.3	-2.1	0.3	1.0	-0.2	0.3	0.0	0.2	0.2	0.5	0.3	-0.4	-0.1	0.5	0.5	0.6	0.0	0.1	0.5	-0.6	-0.1	0.2	0.9
Diastolic blood pressure, automated reading	5.0	15.5	24.8	-1.0	-3.9	-1.4	-4.1	-4.3	-4.2	-4.3	-4.3	-4.1	-5.0	2.7	-2.8	-4.3	-4.7	-4.1	-4.4	-4.3	-4.3	4.2	-3.8	-4.3	-3.4
Ever depressed for a whole week	2.1	2.6	4.5	1.2	-0.6	-0.4	-0.4	-2.1	-2.1	-2.0	-1.6	-1.8	-1.4	0.5	0.1	-2.0	-1.6	-2.0	-2.1	-2.1	-1.8	2.0	-0.4	-2.1	-1.5
Unable to work because of sickness or disability	0.2	0.3	2.3	-1.5	-0.3	-1.3	0.3	0.2	0.3	0.2	0.5	0.3	-0.6	0.7	0.5	0.2	-0.2	0.2	0.2	0.4	0.2	-0.2	-0.5	0.2	0.5
Commuting to job workplace: Cycle	0.4	0.4	1.6	0.6	-0.2	-0.1	-1.3	-0.7	-0.7	-0.3	-1.2	-0.9	-1.0	-0.0	-0.4	-0.4	-0.1	-0.7	-0.6	-0.6	-0.4	0.7	0.4	-0.7	0.3
Myopia	0.3	0.5	1.8	-0.5	-0.7	0.6	0.3	-0.5	-0.6	-0.8	-0.3	-0.7	-0.9	1.0	-1.3	-0.9	-0.4	-0.4	-0.8	-0.8	-0.8	0.4	-0.3	-0.5	0.2
Vascular/heart problems diagnosed by doctor	0.6	1.8	8.2	0.9	2.0	0.4	0.7	0.8	1.0	0.6	1.7	0.7	2.3	-2.5	0.8	0.5	1.8	0.6	1.0	0.8	0.4	-0.6	2.9	0.9	1.1
Cholesterol lowering medication	0.5	0.8	7.3	0.4	1.4	-1.5	0.8	-0.1	0.1	0.2	-0.8	-0.0	-0.8	2.7	0.6	0.2	0.7	-0.1	0.1	-0.3	0.3	0.1	1.4	0.0	0.4
Medication: Omeprazole (e.g. Zanprol)	1.5	1.9	3.6	-1.0	1.4	-0.4	1.8	1.5	1.6	1.3	1.3	1.3	1.1	0.6	1.0	1.1	1.9	1.5	1.4	1.5	1.1	-1.5	1.9	1.5	1.2
Pain experienced in last month	1.5	2.5	6.9	0.8	0.3	-0.8	1.9	1.8	1.6	1.7	1.4	1.4	1.8	-1.4	-0.2	1.8	1.5	1.9	1.7	1.6	1.7	-1.9	0.8	1.7	2.6
Supplements: Calcium	1.6	1.7	3.5	0.7	0.3	-0.2	0.8	1.6	1.6	1.8	1.2	1.4	1.1	-0.5	0.6	1.8	0.9	1.4	1.7	1.8	1.7	-1.4	-0.6	1.6	1.9
Basal cell carcinoma (self-reported)	0.4	0.5	1.3	-1.0	-0.8	1.0	-0.3	-0.7	-0.6	-0.5	-0.7	-0.5	0.0	-1.1	-0.9	-0.6	-0.5	-0.5	-0.8	-0.8	-0.6	0.6	-0.3	-0.7	-1.0
Heart attack/myocardial infarction (self-reported)	1.2	1.5	5.1	1.3	-0.7	0.2	-2.3	-1.3	-1.3	-0.9	-1.7	-1.1	-1.7	0.5	-0.9	-0.8	-1.3	-1.3	-1.1	-1.2	-0.8	1.3	-1.0	-1.3	-1.2
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	0.6	-0.8	0.3	0.8	0.1	0.3	0.0	0.3	-0.4	0.1	0.1	-0.7	-0.7	0.3	0.2	0.4	0.1	0.5	0.1	-0.4	-0.1	0.1	-0.4
Heart disease (siblings)	1.0	1.2	2.3	-0.9	0.2	0.8	0.9	1.4	1.5	1.3	1.3	1.5	0.9	-0.3	0.7	1.1	0.5	1.3	1.4	1.4	1.3	-1.3	-1.0	1.4	0.1
Alcohol drinker status: Previous	1.7	2.0	6.9	-0.1	1.4	2.6	2.0	1.5	1.4	1.1	1.6	1.5	1.3	0.4	1.7	1.1	1.2	1.6	1.4	1.4	1.2	-1.6	0.5	1.5	0.7
Pack years of smoking	0.9	1.3	2.8	-0.7	0.6	0.1	0.1	1.4	1.2	1.3	1.4	1.4	0.4	1.5	0.8	1.5	1.1	1.7	1.2	1.3	1.4	-1.7	-0.3	1.3	0.4
Impedance of whole body	0.1	0.6	2.5	-0.7	-1.6	-0.8	-0.7	-0.6	-0.9	-0.0	-0.0	-0.3	-1.2	0.0	-0.0	0.1	-0.6	-0.4	-0.6	-0.9	-0.0	0.4	-0.9	-0.7	-1.6
Leg fat mass (left)	0.4	1.6	3.4	0.4	-1.1	-1.3	-0.7	-1.5	-1.3	-1.6	-1.9	-1.6	-0.9	0.8	-0.4	-1.5	-1.3	-1.5	-1.3	-1.3	-1.4	1.5	-0.5	-1.4	1.4
Arm predicted mass (left)	0.4	2.0	3.5	0.2	-0.4	-0.8	-1.3	-1.6	-1.3	-1.9	-1.8	-1.8	-0.1	-1.7	-1.8	-1.8	-1.2	-1.6	-1.5	-1.3	-1.8	1.6	-0.0	-1.5	1.1