Hub : Genes

NAB1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0620	0.0250	6.9e-05	0.062	0.041	0.027	0.043	0.044	4.3e-08	7.9e-06	2.9e-04	5.3e-06	4.3e-06
2	GTEx	Adipose Visceral Omentum	0.1510	0.0740	5.6e-03	0.004	NA	-0.004	NA	0.002	1.8e-01	NA	6.0e-01	NA	2.5e-01
3	GTEx	Esophagus Mucosa	0.3410	0.0620	2.2e-15	0.278	NA	0.277	NA	0.289	9.2e-19	NA	1.0e-18	NA	1.3e-19
4	GTEx	Esophagus Muscularis	0.1270	0.0520	2.1e-03	0.128	NA	0.080	NA	0.117	3.5e-08	NA	1.3e-05	NA	1.4e-07
5	GTEx	Testis	0.1440	0.0510	1.5e-04	0.056	NA	0.096	NA	0.084	1.6e-03	NA	5.1e-05	NA	1.4e-04
6	TCGA	Cervical Squamous Cell Carcinoma	0.1190	0.0570	3.3e-03	0.051	0.041	0.055	NA	0.056	1.6e-03	4.4e-03	1.1e-03	NA	9.4e-04
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0557	0.0262	5.6e-04	0.036	0.021	0.031	NA	0.034	5.4e-05	1.6e-03	2.0e-04	NA	9.8e-05
8	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0480	0.0260	8.0e-03	0.023	0.038	0.031	NA	0.029	1.7e-02	2.9e-03	7.0e-03	NA	8.8e-03
9	TCGA	Pancreatic Adenocarcinoma	0.1330	0.0760	1.0e-02	0.018	0.046	0.010	NA	0.019	5.7e-02	5.1e-03	1.2e-01	NA	5.3e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.1	0.1	0.4	-0.1	0.4	0.0	0.7	0.2	-0.5	-0.5	-0.3	0.4
Bipolar Disorder or Schizophrenia	0.7	1.6	6.5	-0.5	1.5	-0.6	-0.3	1.1	-1.5	-2.5	-1.4	0.1
Depressed Affect (Nagel 2018)	0.7	1.4	3.2	-0.6	1.1	-0.8	-0.1	1.7	-1.2	-1.7	-1.8	-0.2
Depression (Nagel 2018)	1.3	1.9	4.5	-0.9	1.5	-0.4	-0.2	1.9	-1.3	-2.1	-2.0	-0.5
Intelligence (Savage-Jansen 2018)	0.3	0.8	2.8	-0.4	1.2	-1.7	-0.7	0.9	0.8	0.6	-0.6	0.3
Neuroticism (Nagel 2018)	1.4	3.3	6.3	-1.6	1.2	-0.8	-0.7	2.3	-2.4	-1.9	-2.5	-2.0
Schizophrenia (2018)	1.0	2.1	8.4	-0.6	1.5	-0.8	-0.9	1.3	-1.6	-2.9	-1.6	-0.2
Schizophrenia vs Biploar Disorder	0.8	1.1	3.5	-1.5	1.4	-0.9	0.7	1.9	-0.2	-0.6	-0.1	0.1
Worry (Nagel 2018)	0.8	1.6	7.7	-0.8	0.4	-0.4	-1.1	0.9	-1.8	0.1	-0.9	-2.8
Alzheimer’s Disease (in mother)	2.3	2.7	8.6	-0.4	0.9	1.2	-1.0	0.7	-2.0	-2.9	-2.4	-1.6
Alzheimer’s Disease (in father)	0.2	0.2	0.8	0.8	-0.3	0.9	-0.3	-0.1	0.3	-0.2	-0.0	0.4
Alzheimer’s Disease (including proxy)	0.8	1.2	3.4	0.2	0.7	0.7	-1.1	0.5	-1.6	-1.8	-1.3	-0.8
Crohns Disease (2017)	1.1	2.5	6.9	-0.1	-1.4	-0.2	0.3	-1.6	-2.6	-1.5	-1.5	-2.6
Irritable Bowel Disease (IBD)	0.1	0.3	1.0	0.1	-0.5	0.2	0.7	-1.0	-0.4	-0.7	-0.6	-0.0
Ulcerative Colitis (UC)	0.7	1.3	6.5	0.2	0.8	0.0	0.7	0.0	1.9	0.6	0.6	2.5
Major Depression (MDD)	1.3	1.6	4.7	-0.8	1.5	0.6	-0.1	2.2	0.6	-1.6	-1.7	0.3
Reaction Time	1.6	3.1	6.6	1.2	-2.5	-0.4	-0.9	-2.6	-2.4	-2.1	-0.7	-1.4
Verbal and Numeric Reasoning (VNR)	0.4	0.9	3.3	-0.8	1.1	-1.8	0.2	1.4	0.2	0.4	-0.4	0.6
Breast Cancer	1.1	2.6	9.4	2.4	-2.0	0.2	-0.9	-3.1	0.7	1.1	1.4	-0.0
Ovarian Cancer	0.3	0.4	1.1	0.0	0.3	-0.1	-0.4	0.7	1.1	0.7	1.0	0.4
Prostate Cancer	1.7	2.4	6.7	-1.0	1.6	-2.6	2.0	1.5	0.4	1.0	1.1	1.5
Age at First Birth	0.7	0.9	3.1	0.5	-0.6	-0.4	0.2	1.0	1.8	-0.6	0.8	1.6
Bipolar Disorder (2011)	1.9	1.8	5.9	-0.8	1.4	1.2	0.5	0.9	-0.9	-2.4	-2.1	-0.4
Body Mass Index (BMI) (2010)	0.6	0.9	2.6	-1.0	1.6	-0.3	0.9	1.4	-0.1	-0.6	-1.1	0.0
Coronary Artery Disease (CAD)	2.2	2.6	8.0	-2.2	1.5	-1.2	2.8	2.3	0.7	0.8	-0.6	0.5
Crohns Disease (2012)	1.2	2.0	5.6	-0.6	-0.6	-1.5	2.1	-0.5	-2.4	-0.4	-1.0	-1.8
Mean Putamen Volume	0.3	0.3	1.5	-0.3	-0.2	0.2	-0.2	0.2	1.2	-0.1	0.3	0.9
Fasting Glucose	0.4	0.5	2.7	0.3	0.8	0.6	1.6	0.4	0.3	0.1	-0.1	0.7
HbA1C	0.4	0.4	1.5	-0.2	0.3	0.9	-0.0	1.2	0.9	-0.2	-0.5	-0.5
HDL Cholesterol	0.1	0.2	0.8	0.0	-0.4	0.9	0.0	-0.7	0.3	-0.0	0.2	0.6
LDL Cholesterol	2.1	3.3	9.4	1.8	-0.4	1.5	-1.1	-0.9	3.1	2.1	2.2	1.8
Lupus	17.9	27.2	75.9	-8.7	5.6	-2.0	3.5	6.4	-3.1	-3.1	-6.2	-4.7
Neuroticism (2016)	0.8	1.1	4.2	-0.1	0.1	-0.5	0.5	1.0	-2.1	-1.6	-1.0	-0.8
Primary Biliary Cirrhosis	11.7	16.6	38.6	-4.6	1.2	-2.0	2.1	1.5	-5.8	-3.6	-5.7	-6.2
Rheumatoid Arthritis	7.8	10.7	23.4	-4.8	3.0	1.2	1.5	4.2	-1.2	-2.9	-4.5	-3.4
Schizophrenia (2014)	1.4	3.1	7.9	-1.6	1.9	-1.0	0.2	2.2	-1.9	-2.8	-2.0	-0.4
Triglycerides	2.6	4.3	13.5	2.3	-0.9	1.0	-0.5	-1.4	3.7	1.7	2.3	2.8
Type 2 Diabetes (T2D) (2012)	0.5	0.6	1.5	-0.2	0.5	0.4	-1.2	1.0	1.1	-0.8	-0.6	-0.1
Ulcerative Colitis	0.8	1.1	3.6	0.2	-0.0	-0.5	1.4	0.0	1.2	1.2	1.1	1.9
Blood Eosinophil Count	1.1	8.7	17.6	4.2	-3.2	0.3	-3.0	-3.5	2.1	1.6	3.3	3.3
Blood Platelet Count	1.5	17.2	40.3	4.9	-1.1	-0.7	-1.6	-0.8	5.4	4.9	5.7	6.3
Blood Red Count	1.0	9.3	17.3	4.0	-4.2	0.1	-2.8	-3.4	1.0	3.7	3.8	1.1
Blood White Count	0.7	5.4	11.2	3.2	-3.3	0.5	-3.3	-0.5	2.1	1.3	2.3	2.1
Heel T-Score	3.3	26.3	62.7	7.5	-7.9	-2.4	-4.6	-6.7	1.7	3.6	5.0	2.0
BMI	0.1	0.6	2.8	0.0	-1.7	-0.0	0.7	-1.4	-0.5	0.5	0.3	-0.0
Height	1.2	23.0	62.9	-7.5	5.8	-3.2	3.1	7.9	-2.8	0.0	-3.2	-4.0
Waist Hip Ratio (WHR)	0.2	1.1	3.4	-0.2	1.5	1.8	-0.7	1.3	1.0	-0.5	-0.9	-0.1
Systolic Blood Pressure	4.8	24.2	49.7	5.8	-6.8	-0.3	-1.9	-6.9	1.1	5.8	7.0	1.4
Smoking Status	0.3	0.8	3.6	-0.1	0.7	1.0	-0.4	-0.1	-0.2	-1.9	-1.1	-0.6
Allergy or Eczema	1.8	4.7	17.4	0.6	-1.6	-3.7	0.6	-1.3	-4.2	-0.6	0.2	-2.5
Cardiovascular Disease	2.0	6.7	16.5	2.7	-4.0	-1.9	-1.3	-4.1	-1.9	2.0	2.9	0.1
Hypothyroidism (self reported)	9.3	21.3	41.6	-6.5	5.0	-1.5	4.3	5.8	-3.3	-3.9	-5.7	-3.4
Respiratory disease	1.0	2.2	8.9	0.2	-1.2	-2.3	-0.4	-0.7	-3.0	-0.3	0.1	-1.8
Type 2 Diabetes (T2D) (2018)	0.4	0.8	1.9	-0.8	0.7	1.0	-0.5	1.3	1.4	-0.8	-0.7	0.4
Lung FEV1/FVC ratio	0.3	1.5	3.6	0.9	-1.8	-0.1	0.6	-1.9	-0.1	1.8	1.4	-0.1
Lung FVC	1.2	6.0	19.1	1.7	-2.9	-2.7	-1.8	-1.9	-0.9	4.4	2.8	-1.3
Neuroticism	0.5	1.3	2.9	-1.0	0.2	-0.8	-0.1	1.4	-1.7	-0.7	-1.4	-1.6
Chronotype (morning person)	2.0	4.7	13.9	1.6	-1.7	-1.0	1.5	-2.4	1.9	2.1	3.7	2.5
Hair Pigment	0.1	2.2	4.2	-2.0	0.8	2.0	1.5	1.0	-1.9	0.2	-0.9	-1.7
Tanning	0.0	0.4	1.2	0.1	-0.2	-0.6	1.1	-0.2	-0.0	0.4	0.9	1.0
Hand grip strength (left)	1.0	2.7	8.9	-2.5	1.9	1.6	0.7	3.0	-0.6	-1.2	-1.1	-0.1
Number of treatments/medications taken	1.0	1.8	5.2	-0.3	-0.8	-2.3	0.2	-0.5	-2.3	0.5	-0.2	-2.1
Average weekly spirits intake	2.1	2.7	9.3	0.4	-1.3	2.0	-2.2	-0.7	-0.9	-0.8	-1.5	-3.0
Sensitivity / hurt feelings	1.0	1.7	3.6	0.9	-1.6	-1.9	-1.9	-0.6	-1.6	0.5	0.3	-1.2
Frequency of depressed mood in last 2 weeks	0.6	0.8	2.0	-0.4	0.7	-0.2	0.1	0.5	-1.3	-1.4	-1.3	-0.8
Hearing difficulty/problems: Yes	0.2	0.3	1.2	-0.7	0.4	-0.0	-0.0	0.3	1.1	1.0	0.1	-0.3
Relative age of first facial hair	0.4	0.9	2.5	-1.0	1.5	-0.7	-0.2	1.1	-1.6	-0.3	-0.3	-0.6
Other serious medical condition/disability diagnosed by doctor	3.8	4.9	9.5	-2.7	1.6	-2.2	0.8	2.8	-2.2	-2.0	-3.1	-1.7
Ever used hormone-replacement therapy (HRT)	0.8	1.0	3.0	0.8	-0.2	0.8	1.2	-1.7	0.5	0.9	1.0	1.0
Ever had hysterectomy (womb removed)	1.5	1.7	4.0	1.6	0.3	0.4	0.2	-1.5	1.3	1.2	1.9	2.0
Systolic blood pressure, automated reading	3.5	10.3	19.7	4.2	-4.3	-0.4	-1.9	-4.4	0.4	3.6	4.4	0.6
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	1.8	-1.0	0.9	0.3	0.7	1.3	1.3	0.3	0.4	0.5
Angina	0.9	1.2	2.2	1.1	-1.4	0.5	-0.7	-1.5	0.8	1.5	1.3	0.3
Medication for hormone replacement therapy	1.3	1.5	4.5	0.8	0.1	-0.3	0.4	-1.5	0.9	2.1	1.4	1.7
Vitamin and mineral supplements	1.7	2.3	5.1	1.5	0.1	0.9	1.1	-1.8	1.0	2.3	2.1	1.5
Supplements: Zinc	1.5	1.7	4.2	-1.6	1.5	-1.0	0.7	2.0	-0.2	-1.7	-1.2	0.6
Medication: Co-codamol	1.3	1.5	9.1	0.4	-0.8	-3.0	1.0	-1.0	-0.8	1.0	0.3	-0.2
Medication: Metformin	0.4	0.5	3.5	0.7	-1.9	0.4	-0.3	-0.3	0.5	-0.0	0.5	0.2
Diabetes (father)	1.0	1.2	3.1	-1.8	1.5	-0.3	1.4	1.3	-0.1	-0.5	-1.2	-0.5
Diabetes (mother)	0.6	0.7	1.8	1.4	-1.1	0.8	-1.2	-0.6	0.9	-0.6	-0.4	-0.2
Severe depression (siblings)	0.7	0.8	3.8	-0.5	0.7	-1.2	0.2	0.2	-2.0	-0.4	-0.7	-0.7
Pack years adult smoking proportion	0.8	1.2	3.4	0.6	-1.0	-1.8	1.1	-0.0	0.5	0.6	1.2	1.7
Impedance of leg (right)	0.1	0.5	1.2	0.4	0.2	-0.3	-0.3	-0.7	-1.0	-1.0	-0.7	-1.1
Leg fat-free mass (left)	0.3	1.4	4.0	-1.9	0.6	-0.4	1.8	2.0	-0.2	0.8	0.3	0.2
Trunk fat percentage	0.5	2.0	5.9	0.6	-2.4	0.2	1.6	-2.4	-1.3	0.7	0.8	-1.0
Hand grip strength (right)	1.0	2.7	7.1	-1.9	2.1	2.2	0.2	2.7	0.2	-1.4	-1.6	-0.1
Townsend deprivation index at recruitment	0.4	0.6	2.6	0.3	-0.6	-0.2	0.3	-0.1	0.5	0.8	1.6	1.2
Current tobacco smoking	0.3	0.4	2.3	-0.1	-0.3	-1.0	1.5	-0.4	-0.3	0.1	0.3	0.2
Average weekly fortified wine intake	0.7	0.8	3.2	-0.8	1.3	-1.8	0.6	0.3	-0.8	0.4	-0.2	-0.5
Maternal smoking around birth	0.4	0.6	1.8	-0.5	-0.3	0.4	-1.2	0.8	0.0	-0.8	-1.3	-0.7
Fed-up feelings	0.4	0.7	4.0	0.3	-0.4	-0.0	-2.0	0.3	-0.1	-0.4	-1.1	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.7	-0.0	0.8	-0.6	0.2	0.2	-0.5	-0.1	-0.1	0.6
Relative age voice broke	0.2	0.4	1.1	0.5	-0.6	0.1	-1.0	-0.4	-1.0	-0.5	0.3	-0.5
Taking other prescription medications	1.6	2.4	12.6	-0.9	0.0	-3.5	0.3	1.1	-1.8	1.2	-0.1	-1.5
Age when periods started (menarche)	1.8	4.2	9.5	2.3	-2.4	-0.9	0.4	-3.1	0.3	2.7	3.0	0.6
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	1.7	-0.2	0.6	1.3	1.2	-0.0	1.2	0.9	0.5	1.0
Heel bone mineral density (BMD) T-score, automated (left)	2.0	4.5	9.6	2.9	-3.1	-0.4	-1.0	-1.4	2.0	2.1	2.5	2.1
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	4.0	-0.8	1.8	0.3	0.9	1.2	1.4	0.8	0.6	2.0
Qualifications: CSEs or equivalent	0.2	0.2	0.6	0.1	-0.1	-0.7	-0.0	-0.8	-0.4	0.7	0.4	0.3
Serious illness, injury or assault to yourself	1.2	1.4	4.7	-1.5	1.1	-0.1	0.2	2.2	0.1	-1.4	-1.6	-0.3
High blood pressure	1.2	3.5	9.1	2.1	-3.0	-1.2	-1.2	-2.6	-1.8	1.0	2.0	-0.1
Hayfever, allergic rhinitis or eczema	1.7	3.8	14.3	0.3	-0.9	-3.8	1.0	-1.1	-3.5	-0.5	-0.2	-2.1
Multivitamins +/- minerals	2.6	3.3	11.2	-0.8	0.1	-1.1	-1.4	1.0	-2.2	-3.4	-2.5	-1.6
Stomach or abdominal pain in last month	0.8	1.0	2.4	-1.2	0.5	-0.6	-0.4	0.1	-1.5	0.1	-1.4	-1.5
Supplements: Glucosamine	0.6	0.7	2.0	-0.9	-0.3	-0.5	1.2	-0.6	-1.4	-0.5	-0.7	-1.1
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.6	0.4	0.8	-0.6	-0.4	0.0	0.3	-0.3	-0.5	0.5
Medication: Atenolol	1.2	1.6	3.8	0.7	-1.4	-1.2	0.7	-1.9	-0.4	1.8	1.4	-0.0
Medication: Levothyroxine sodium	7.9	13.4	28.9	-5.4	4.6	-1.6	3.5	5.4	-1.3	-2.1	-4.1	-1.9
Sitting height	0.8	5.9	16.5	-3.7	2.8	-1.8	3.3	4.1	-0.5	0.8	-0.1	-0.1
Chronic bronchitis/emphysema (father)	2.0	2.4	10.5	1.9	-1.5	-0.8	0.2	-3.2	-0.9	0.9	1.6	0.4
High blood pressure (mother)	1.2	1.7	5.2	0.2	-1.3	0.8	0.9	-0.3	1.6	2.3	1.8	1.1
Body mass index (BMI)	0.2	0.8	3.5	0.5	-1.9	0.9	0.1	-1.5	-0.6	0.1	0.1	-0.3
Impedance of leg (left)	0.0	0.2	0.5	0.4	0.0	0.2	-0.1	-0.6	-0.4	-0.7	-0.5	-0.7
Leg predicted mass (left)	0.3	1.4	4.0	-1.9	0.5	-0.4	1.8	2.0	-0.4	0.7	0.2	0.1
Trunk fat mass	0.3	1.1	2.8	-0.2	-1.6	0.1	1.7	-1.1	-1.4	0.5	0.4	-1.1
Waist circumference	0.1	0.3	0.6	-0.2	-0.6	0.7	-0.2	-0.2	-0.8	0.0	-0.5	-0.8
Number of incorrect matches in round	0.7	1.2	3.6	-0.8	1.2	-1.9	0.1	0.2	-1.2	-1.6	-0.8	0.6
Past tobacco smoking	0.4	0.8	2.8	-0.5	-0.7	-1.7	1.1	1.0	-0.7	0.8	0.4	0.3
Alcohol usually taken with meals	2.0	3.2	7.4	-1.7	1.3	-1.1	0.3	2.2	-1.6	-2.4	-2.7	-1.4
Nervous feelings	0.3	0.6	1.8	0.3	-0.2	-0.1	-1.3	-0.1	-0.4	1.3	0.9	-0.9
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	3.6	-0.4	-0.3	-0.7	-1.9	0.4	-1.6	-1.1	-1.3	-1.7
Hearing difficulty/problems with background noise	0.4	0.6	2.1	-0.8	0.7	-1.4	-0.8	0.6	-0.4	-0.1	-0.8	-0.7
Hair/balding pattern: Pattern 2	0.9	1.2	3.6	0.0	0.4	1.6	0.9	0.6	1.6	0.5	0.3	1.9
Had menopause	1.1	1.4	6.6	-0.4	0.5	0.1	-0.2	-0.5	-1.8	-0.4	-1.2	-2.6
Had other major operations	0.6	0.8	2.9	0.3	-0.0	-1.6	-0.5	-0.6	0.2	1.7	0.8	0.1
Forced vital capacity (FVC)	1.3	5.2	14.1	-3.8	2.2	-2.7	1.8	3.6	-0.9	1.5	-0.4	-0.9
Heel bone mineral density (BMD) T-score, automated (right)	1.9	4.3	10.5	2.9	-3.2	-1.6	-1.5	-1.2	1.0	1.7	2.5	1.7
Ever unenthusiastic/disinterested for a whole week	1.8	2.1	7.2	-1.6	2.0	0.2	1.9	2.7	0.6	-0.5	-0.8	1.0
Qualifications: None of the above	3.2	6.8	14.6	3.5	-2.8	0.2	-1.6	-3.8	1.0	2.5	3.7	1.7
Financial difficulties in last 2 years	0.8	1.1	4.8	1.0	-0.3	-1.6	0.4	-1.1	-2.2	0.1	0.4	0.0
Mouth/teeth dental problems	0.9	1.3	2.2	0.8	1.4	1.2	1.1	-1.4	1.2	-0.9	0.4	1.5
Heart attack	0.4	0.5	1.8	0.6	-0.6	-0.7	0.0	-0.2	0.1	1.2	1.3	0.5
Allergy	2.5	5.7	20.6	-0.6	1.6	3.9	-0.0	1.9	4.5	0.6	0.4	3.0
Pain all over the body in last month	1.9	2.1	6.2	2.5	-1.1	-0.3	-1.9	-2.0	0.5	1.1	1.2	0.9
Diabetes (self-reported)	0.3	0.5	1.2	-0.2	-0.1	0.8	0.3	0.7	1.0	-1.1	-0.3	0.9
Hayfever/allergic rhinitis (self-reported)	1.3	1.7	6.5	0.6	-0.3	-2.6	-0.2	-0.8	-2.4	0.3	0.0	-1.4
Medication: Ramipril	0.8	1.1	3.8	0.5	-0.2	0.1	-1.9	-0.5	1.4	1.3	0.9	0.8
Medication: Simvastatin	2.3	3.4	5.7	2.0	-1.4	0.5	-1.0	-1.8	2.4	2.2	2.0	2.4
Fluid intelligence score	0.4	0.8	3.3	-0.7	1.0	-1.8	0.5	1.1	-0.1	-0.2	-0.7	0.6
Illnesses of siblings	0.9	1.2	4.1	-0.8	0.5	0.3	-0.2	0.7	-0.8	-1.4	-1.6	-2.0
Neuroticism score	0.4	0.7	2.2	-0.6	0.4	-0.8	-0.5	0.7	-1.5	-0.0	-0.8	-1.4
Weight	0.2	0.9	2.7	-1.6	-0.2	-0.3	1.7	0.9	-1.1	0.5	-0.0	-0.6
Impedance of arm (right)	0.6	2.9	5.6	0.9	-2.4	-2.3	0.8	-2.3	-1.6	1.3	1.1	-1.6
Arm fat percentage (right)	0.7	2.6	9.7	0.8	-3.1	0.2	0.2	-2.8	-1.8	0.5	0.4	-1.5
Trunk fat-free mass	0.7	3.8	15.6	-3.2	2.2	-0.4	1.6	4.0	-0.5	-0.1	-0.7	-0.0
Hip circumference	0.2	1.0	2.6	-1.5	-0.5	-0.7	1.4	0.1	-1.6	0.0	-0.8	-1.2
Time employed in main current job	1.0	1.2	4.5	0.6	-1.6	-2.1	-1.0	-0.5	-0.1	1.1	0.8	0.2
Alcohol intake versus 10 years previously	0.8	1.3	5.1	-0.9	0.9	-2.2	1.1	1.2	-1.0	0.3	0.6	0.7
Father’s age at death	0.3	0.4	2.1	-0.5	1.0	-1.4	0.1	-0.2	0.1	-0.4	-0.3	0.3
Worrier / anxious feelings	0.7	1.2	3.8	0.1	-1.1	-1.3	-0.8	-0.6	-1.7	0.7	-0.0	-2.0
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	2.2	1.0	-1.5	-0.8	-0.4	-1.0	-0.2	1.5	1.1	0.3
Falls in the last year	1.4	1.9	5.1	-1.7	2.3	-1.2	1.3	1.6	-0.5	-1.4	-1.0	0.5
Hair/balding pattern: Pattern 3	0.7	1.0	2.2	-1.5	-0.1	-1.0	0.2	0.7	-0.8	-1.2	-1.3	-1.0
Number of live births	0.6	0.9	2.9	0.2	-0.1	-0.5	1.1	-0.3	0.4	1.5	1.7	1.1
Forced expiratory volume in 1-second (FEV1)	0.7	2.4	5.9	-2.4	1.1	-1.9	1.4	2.2	-0.4	2.0	0.4	-0.5
Pulse rate	2.1	3.6	8.0	2.2	-2.6	0.1	-1.0	-2.3	0.0	2.4	2.8	0.5
Happiness	0.7	0.9	3.0	0.4	1.1	0.4	-0.6	0.4	0.3	-1.7	-1.1	1.2
Noisy workplace	0.5	0.6	2.0	-0.4	1.4	1.4	0.5	0.3	0.8	0.5	-0.2	0.6
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.8	-0.9	1.0	0.3	-0.1	1.4	0.3	0.1	-0.8	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.7	-0.0	-0.2	-1.0	1.3	0.2	-0.3	-0.3	0.1	0.9
Mouth/teeth dental problems: Dentures	0.9	1.4	3.7	0.3	-1.4	-1.9	0.1	-0.6	-1.3	1.9	1.2	-0.5
Asthma	1.1	2.2	7.5	0.7	-1.4	-2.7	-0.3	-1.0	-2.2	1.3	1.2	-1.0
Medication: Ibuprofen (e.g. Nurofen)	1.9	2.4	6.0	2.3	-1.4	-0.8	-1.7	-2.5	0.1	1.0	1.5	1.0
Medication: Cholesterol lowering	0.9	1.3	2.8	1.1	-1.7	-0.9	0.0	-1.6	-0.1	1.5	1.5	-0.4
Depression (self-reported)	4.2	5.1	11.9	-2.6	2.2	-0.8	-0.1	2.2	-1.8	-2.8	-3.5	-2.4
Medication: Lansoprazole	0.6	0.7	2.4	1.1	-0.3	-0.6	-1.6	-0.2	0.3	0.8	0.8	0.8
Prospective memory result	1.1	1.3	5.5	1.3	-0.3	2.3	-1.2	-1.0	1.2	0.0	0.6	0.4
Lung cancer (father)	1.2	1.4	2.9	-1.5	0.8	1.1	1.1	0.5	-0.6	-0.9	-1.6	-1.7
Illnesses of mother	0.1	0.1	0.2	-0.3	0.5	-0.2	-0.1	-0.1	0.2	-0.2	-0.3	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	2.1	4.8	-1.4	0.7	-1.9	1.8	1.1	-0.6	2.2	1.4	0.6
Pulse wave Arterial Stiffness index	0.4	0.4	2.4	0.7	-0.4	-0.4	-0.0	-1.5	-0.3	0.5	0.4	-0.3
Impedance of arm (left)	0.4	1.7	3.3	0.5	-1.4	-1.8	1.2	-1.8	-1.4	0.6	0.6	-1.5
Arm fat mass (right)	0.2	0.9	3.5	-0.1	-1.9	0.3	0.8	-1.1	-1.3	0.4	0.2	-1.0
Trunk predicted mass	0.7	3.9	16.5	-3.2	2.1	-0.4	1.6	4.1	-0.5	-0.1	-0.8	-0.0
Standing height	1.0	9.8	28.8	-4.6	3.6	-2.8	3.9	5.4	-1.2	0.8	-0.3	-0.5
Length of working week for main job	1.3	1.4	2.5	1.6	-1.1	0.5	-1.2	-1.4	1.2	0.5	1.3	1.4
Exposure to tobacco smoke at home	0.9	1.1	4.5	0.7	-0.2	-0.0	0.5	-0.4	0.8	0.7	1.7	2.1
Breastfed as a baby	0.5	0.6	1.6	-0.5	0.8	-1.3	0.6	1.2	-0.3	-0.8	-0.4	0.6
Tense / ‘highly strung’	0.4	0.6	2.9	-0.3	-0.1	-0.3	-1.3	0.4	-0.5	0.3	-0.5	-1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.8	2.8	5.3	-2.1	1.3	-0.4	-0.8	1.9	-1.5	-1.5	-2.3	-2.2
Hair/balding pattern: Pattern 4	1.7	4.2	7.8	2.8	-2.5	2.3	-2.8	-2.7	-0.4	0.5	1.3	-1.0
Birth weight of first child	0.5	1.0	3.9	-0.2	1.3	0.2	2.0	0.7	0.7	0.4	0.4	1.2
Peak expiratory flow (PEF)	2.2	5.1	17.3	1.0	-1.6	-3.5	0.4	-1.6	-0.5	4.2	3.0	0.7
Pulse wave reflection index	0.8	0.9	2.2	0.3	0.1	-0.2	-0.7	-1.0	-1.5	-1.3	-1.3	-1.1
Ever highly irritable/argumentative for 2 days	0.9	1.1	2.5	-0.0	1.1	0.5	0.4	1.3	1.0	1.3	1.0	1.6
Loud music exposure frequency	0.6	0.7	3.1	0.6	-0.4	1.2	-0.1	0.2	-0.6	-1.8	-0.8	0.3
Qualifications: O levels/GCSEs or equivalent	0.9	1.5	5.3	1.9	-1.3	0.2	-2.3	-1.4	-0.1	-0.3	0.2	-0.8
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	4.9	-0.1	-2.2	-0.9	-1.1	0.6	-0.6	0.7	-0.2	-1.2
Blood clot in the leg (DVT)	0.1	0.2	0.5	-0.7	0.1	-0.1	0.0	-0.3	-0.1	0.0	-0.7	-0.5
Medication: Paracetamol	2.3	3.9	7.9	2.8	-2.7	-0.1	-2.2	-2.8	-1.2	1.2	1.3	-1.6
Headache pain in last month	0.5	0.8	1.8	0.5	-1.0	-0.8	-1.0	-1.2	-0.1	1.0	0.3	-1.3
Medication for cholesterol, blood pressure or diabetes	1.2	2.0	3.8	-1.7	1.8	-0.1	0.4	1.9	-0.9	-1.8	-1.9	-0.7
Glaucoma (self-reported)	0.1	0.1	0.7	0.9	-0.2	-0.1	0.1	-0.4	-0.1	-0.1	0.2	-0.1
Gout (self-reported)	1.3	1.8	3.5	-1.6	0.0	0.3	0.3	1.2	-1.6	-1.8	-1.9	-1.8
Hypothyroidism/myxoedema (self-reported)	9.4	18.3	35.8	-6.0	4.6	-1.8	4.2	5.8	-2.4	-3.6	-5.1	-2.7
Medication: Amlodipine	1.6	2.3	6.6	0.6	-1.0	-2.6	0.2	-0.7	0.2	2.2	2.1	1.6
Medication: Ventolin 100micrograms inhaler	0.5	0.7	1.8	0.7	-1.2	-1.3	-0.6	-0.6	-0.7	0.2	-0.0	-1.0
Birth weight	1.9	4.2	13.1	-2.3	2.9	-0.0	0.6	3.6	0.4	-2.1	-2.4	-0.0
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.6	0.6	-0.5	0.1	-0.6	-0.6	-0.5	-1.2	-0.6	0.0
High blood pressure (siblings)	0.4	0.6	1.4	0.3	-0.6	1.0	0.7	-0.7	0.3	1.2	1.1	0.6
Forced vital capacity (FVC), Best measure	0.7	2.4	6.9	-1.8	0.8	-2.6	1.6	1.8	-1.1	1.8	1.1	0.1
Body fat percentage	0.5	1.8	5.8	0.8	-2.4	0.3	0.8	-2.4	-1.3	0.4	0.6	-1.0
Leg fat percentage (right)	0.4	1.6	4.8	1.0	-2.2	0.7	-0.6	-2.0	-1.4	-0.6	-0.2	-1.1
Arm fat-free mass (right)	0.7	3.5	12.7	-2.7	2.4	0.5	2.1	3.6	0.4	-0.0	-0.4	0.7
Exposure to tobacco smoke outside home	0.9	1.2	3.4	-1.1	1.1	-1.3	0.3	1.3	-1.8	-0.5	-0.9	-0.7
Comparative body size at age 10	0.5	1.3	3.0	-1.7	0.7	0.3	0.3	1.4	-1.0	-1.4	-1.5	-0.4
Number of full brothers	1.0	1.3	2.5	1.4	-0.8	-1.0	-0.0	-1.4	1.0	1.6	1.2	1.2
Worry too long after embarrassment	2.7	4.6	12.6	-1.4	0.8	-1.6	-0.5	1.1	-3.6	-2.3	-2.7	-3.0
Seen a psychiatrist for nerves, anxiety, tension or depression	4.8	6.2	15.3	-3.7	3.9	-0.5	2.2	3.7	-0.9	-1.7	-2.0	-0.6
Wheeze or whistling in the chest in last year	1.4	2.5	10.1	-0.6	-0.8	-2.3	0.4	-0.2	-3.2	-0.9	-1.1	-1.9
Number of children fathered	1.2	1.3	4.6	-0.7	0.2	-0.3	-1.4	0.9	-0.2	-0.8	-1.8	-2.1
Reason for reducing amount of alcohol drunk: Health precaution	1.6	1.8	3.5	1.6	-0.6	-1.5	-0.0	-1.3	-0.0	1.8	1.9	1.7
Age at first live birth	0.2	0.3	1.7	0.3	-1.3	-0.2	0.4	-0.3	0.2	0.2	0.2	-0.8
Pulse wave peak to peak time	0.7	0.9	4.2	-1.4	0.7	-0.1	0.4	2.1	-0.2	-0.6	-0.8	-0.1
Health satisfaction	0.7	0.9	4.0	-1.2	2.0	0.9	1.0	1.1	0.2	0.0	-0.2	0.0
Shortness of breath walking on level ground	0.6	0.7	1.9	0.4	-0.4	0.1	-0.4	0.1	1.4	1.2	1.0	1.2
Qualifications: College or University degree	2.5	7.9	15.8	-3.4	3.3	2.8	1.3	3.6	0.9	-2.9	-4.0	-0.9
Eye problems/disorders: None of the above	1.0	1.2	3.2	0.8	-1.4	1.2	-0.6	-1.8	-0.8	-0.2	0.2	-1.5
Mouth/teeth dental problems: Loose teeth	0.6	0.7	1.8	0.9	-1.0	0.8	-0.6	-0.3	1.4	-0.9	0.0	0.7
Emphysema/chronic bronchitis	1.3	1.5	4.3	0.5	-0.8	-1.4	-0.2	-1.3	-2.1	-1.3	-0.8	-1.5
Medication for pain relief, constipation, heartburn	1.5	2.5	4.9	-2.1	2.2	0.9	1.6	2.0	0.4	-1.6	-1.6	0.1
Neck or shoulder pain in last month	1.2	1.7	4.6	1.7	-1.2	-0.6	-2.1	-0.5	0.4	1.5	1.5	0.9
Medication: Blood pressure	1.6	2.8	4.4	2.0	-2.1	1.0	-1.4	-2.0	1.5	1.7	2.0	1.0
Angina (self-reported)	1.1	1.5	2.8	1.4	-1.6	0.4	-1.1	-1.7	0.8	1.5	1.3	0.3
Migraine (self-reported)	0.8	1.0	1.7	-1.2	1.0	-1.2	0.6	0.6	-1.2	0.3	-0.7	-1.3
Medication: Ibuprofen	1.9	2.3	6.4	2.5	-1.2	-1.0	-1.4	-2.5	-0.1	0.8	1.4	1.1
Medication: Allopurinol	2.0	2.7	7.2	-2.0	0.2	-0.6	-0.0	1.6	-2.7	-1.0	-1.6	-2.6
Medication: Omeprazole	0.1	0.2	0.4	-0.7	-0.5	0.4	0.3	0.4	0.3	0.4	-0.2	0.0
Medication: Seretide 50 evohaler	0.6	0.7	1.5	-0.9	0.8	-0.6	1.2	1.1	0.4	1.1	0.3	0.4
Mean time to correctly identify matches	1.0	2.0	5.6	1.3	-2.4	-0.3	-0.8	-2.4	-1.4	-1.3	-0.1	-0.7
Heart disease (mother)	0.2	0.3	1.5	0.1	0.1	-0.4	-0.2	-0.3	-1.2	-0.2	-0.6	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.1	2.5	4.8	-1.7	1.5	2.2	0.5	2.1	0.3	-1.9	-1.9	-0.5
Whole body fat mass	0.2	0.9	2.8	-0.1	-1.7	0.1	1.0	-1.2	-1.3	0.4	0.4	-1.0
Leg fat mass (right)	0.2	0.7	3.0	0.2	-1.7	0.7	0.2	-1.1	-1.1	0.2	0.1	-0.8
Arm predicted mass (right)	0.6	3.2	12.0	-2.6	2.3	0.4	1.9	3.5	0.4	-0.1	-0.4	0.7
Pulse rate, automated reading	4.2	13.7	27.9	4.7	-5.3	-0.1	-3.1	-4.0	0.3	4.7	5.0	-0.0
Alcohol intake frequency.	0.2	0.5	1.5	-0.2	0.2	-1.2	0.1	0.6	1.1	-0.3	0.1	1.2
Comparative height size at age 10	1.1	6.2	21.9	-3.6	3.4	-1.4	2.6	4.7	0.0	-0.3	-1.1	0.3
Number of full sisters	1.5	1.8	5.1	1.8	-0.6	0.1	0.3	-2.3	0.5	1.4	2.0	1.2
Suffer from ‘nerves’	0.5	0.8	3.0	-0.3	-0.9	-0.6	-1.0	-0.2	-1.4	-0.0	-0.3	-1.7
Overall health rating	1.0	2.2	4.0	1.4	-1.7	-1.6	-1.1	-1.7	-1.3	2.0	1.5	-0.3
Chest pain or discomfort	1.0	1.5	4.7	-1.5	1.2	-0.3	2.2	1.2	0.3	0.8	0.4	1.6
Had major operations	2.5	2.9	10.4	-1.9	1.6	-3.2	2.5	0.6	-1.6	-0.1	-0.4	-0.3
Age at last live birth	0.1	0.2	0.5	0.4	-0.5	0.1	0.7	-0.5	0.6	-0.3	0.2	0.2
Family relationship satisfaction	0.9	1.1	3.8	-0.7	2.0	-0.1	0.7	0.8	-0.4	-1.4	-1.5	0.5
Leg pain on walking	0.9	1.1	3.1	-0.1	-0.1	-1.0	1.8	-1.2	0.1	1.4	1.2	1.2
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	4.2	-0.9	0.1	-2.1	0.0	0.8	-2.0	-0.2	-0.6	-0.9
Commuting to job workplace: Car/motor vehicle	0.8	0.9	2.9	-0.0	-0.1	-1.0	-0.6	1.0	1.3	1.7	1.0	0.2
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	3.3	-1.1	0.8	1.8	-0.4	0.0	0.1	-0.1	-0.6	-1.3
Medication: Aspirin	0.4	0.5	1.4	0.2	-1.2	0.4	-0.9	0.1	-0.9	0.1	0.2	-1.2
Supplements: Vitamin C	1.2	1.4	3.8	-1.5	1.2	-0.3	-0.3	1.8	2.0	-0.2	-0.4	1.1
Knee pain experienced in last month	1.2	1.9	4.4	-1.5	0.1	-1.0	-0.4	0.8	-2.0	-1.1	-2.1	-1.7
Hypertension (Self-reported)	1.0	2.7	6.6	1.6	-2.6	-1.3	-0.9	-2.4	-1.9	0.8	1.5	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.8	2.1	4.8	2.2	-2.0	0.2	-0.9	-1.7	0.9	0.8	1.8	1.3
Illnesses of father: Heart disease	0.5	0.7	2.1	0.8	-0.2	0.3	0.3	-1.5	-0.6	1.4	0.5	-1.1
Illnesses of siblings: Diabetes	0.5	0.6	2.6	0.6	-1.0	0.4	0.4	-0.8	0.8	-0.3	0.2	1.6
Smoking status: Previous	0.6	0.9	2.8	0.6	0.5	1.5	-1.7	-0.9	1.0	-0.8	-0.5	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.5	8.2	-2.9	0.9	-1.6	1.7	2.7	-0.5	0.5	-0.5	-0.5
Whole body fat-free mass	0.5	2.7	10.3	-2.7	1.6	-0.2	1.9	3.2	-0.2	0.3	-0.3	0.2
Leg fat-free mass (right)	0.3	1.6	4.5	-1.9	0.5	-0.3	1.9	2.1	0.3	1.1	0.6	0.6
Arm fat percentage (left)	0.5	2.0	7.3	0.6	-2.7	0.4	0.5	-2.4	-1.5	0.2	0.3	-1.3
Average weekly red wine intake	1.6	2.4	5.2	-1.8	2.1	-0.6	1.2	1.3	-1.1	-1.8	-2.3	-1.0
Handedness (chirality/laterality): Left-handed	1.2	1.4	5.4	-1.1	0.6	-2.3	0.4	0.8	-0.5	2.1	0.6	-0.1
Mood swings	0.6	1.1	4.0	-0.4	0.3	-1.3	1.3	0.2	-2.0	0.2	-0.4	-1.4
Loneliness, isolation	2.4	3.3	10.2	-1.3	1.9	0.5	-0.5	1.7	-1.1	-3.2	-2.9	-0.6
Long-standing illness, disability or infirmity	2.3	3.5	11.2	-1.9	1.1	-3.4	2.7	1.7	-2.0	0.1	-0.9	-0.5
Ever had bowel cancer screening	0.7	0.8	3.4	0.5	0.3	-0.5	-1.9	0.1	-0.9	-0.8	-0.8	-1.1
Diabetes diagnosed by doctor	0.2	0.3	0.6	0.1	-0.6	0.7	-0.5	0.6	0.6	-0.7	-0.1	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	3.7	-0.1	0.2	-1.9	-0.3	0.5	-0.5	0.4	0.5	0.5
Friendships satisfaction	2.2	2.7	6.8	-2.0	2.6	0.7	0.9	2.5	0.4	-1.4	-1.8	0.9
Qualifications: nursing, teaching	2.2	3.4	6.1	-2.2	2.0	0.1	2.2	1.4	-1.7	-2.2	-2.5	-1.1
Commuting to job workplace: Walk	2.0	2.2	6.1	2.5	-1.5	1.0	-1.3	-1.8	0.9	-0.3	1.3	1.8
Eye problems/disorders: Cataract	0.6	0.7	1.7	-0.5	0.9	-0.2	1.3	1.1	0.9	0.5	0.2	1.0
Mouth/teeth dental problems: Mouth ulcers	0.8	1.4	3.3	-0.7	0.8	0.1	-1.8	1.6	-0.9	-1.5	-1.4	-0.7
Medication for cholesterol	1.5	2.3	5.4	-1.5	1.3	1.4	0.9	1.8	-0.4	-2.3	-1.7	-1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	3.4	1.5	-0.5	-1.6	-0.8	-1.8	-0.8	-0.1	0.8	0.8
Back pain experienced in last month	0.3	0.5	1.7	0.2	-1.2	-1.3	-0.2	-0.3	-0.8	0.4	0.1	-0.1
Mineral and other dietary supplements	1.3	1.7	5.7	0.1	1.1	1.8	0.5	0.3	2.4	1.4	0.8	1.4
Breast cancer (self-reported)	0.7	0.9	3.5	-0.6	0.3	-1.2	0.4	0.2	-1.1	0.8	0.3	-1.9
Asthma (self-reported)	0.8	1.6	6.5	0.1	-0.8	-2.5	-0.1	-0.5	-2.1	0.9	0.6	-1.2
Osteoporosis (self-reported)	0.9	1.1	3.5	-0.2	0.4	-1.9	0.7	-0.4	-1.7	0.5	0.3	-1.4
Osteoarthritis (self-reported)	1.8	2.3	6.6	1.7	-0.3	-1.0	0.1	-1.6	0.9	2.6	2.3	1.4
Medication: Aspirin	0.4	0.5	1.4	0.4	-1.1	0.2	-0.6	-0.2	-1.2	-0.0	0.2	-1.2
Medication: Gliclazide	0.8	0.9	2.5	0.9	-0.7	1.6	-0.3	-0.6	1.4	0.6	0.8	0.8
Illnesses of father: None of the above (group 1)	2.4	3.0	9.4	-2.7	1.7	-0.9	0.8	3.1	-0.2	-1.5	-1.9	-0.2
Smoking status: Current	0.3	0.5	2.3	-0.3	-0.2	-0.8	1.5	-0.4	-0.9	-0.5	-0.1	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	1.1	-1.0	1.0	-1.0	0.8	-0.5	-0.9	1.0	0.0	-0.7
Whole body water mass	0.5	2.9	11.1	-2.8	1.8	-0.2	2.0	3.3	-0.1	0.3	-0.3	0.3
Leg predicted mass (right)	0.3	1.6	4.7	-1.9	0.6	-0.3	2.0	2.2	0.3	1.0	0.5	0.6
Arm fat mass (left)	0.2	0.8	2.5	-0.4	-1.6	0.3	1.0	-0.8	-1.2	0.3	0.1	-0.9
Number of self-reported non-cancer illnesses	1.5	2.7	14.4	0.4	-0.8	-3.8	-0.2	-1.0	-1.9	1.7	0.8	-0.8
Average weekly champagne plus white wine intake	3.6	5.0	13.5	-1.9	1.8	0.2	1.4	2.7	-1.7	-3.7	-3.3	-1.0
Miserableness	0.3	0.5	2.2	-0.5	0.6	-1.5	1.2	0.2	-0.6	0.0	-0.3	0.4
Guilty feelings	1.9	2.9	5.7	-2.3	1.5	0.9	0.5	2.0	-1.4	-1.6	-2.4	-1.8
Wears glasses or contact lenses	0.8	0.9	2.8	-0.3	-0.6	-0.8	0.1	-1.3	-1.3	0.5	-0.7	-1.7
Ever taken oral contraceptive pill	1.2	1.3	4.3	-1.5	0.4	-2.1	0.4	2.1	-0.5	0.1	-0.6	-0.3
Hearing aid user	0.8	0.9	3.7	0.0	-0.3	-1.1	-0.1	-0.8	-0.6	1.9	1.3	-0.9
Mother’s age at death	0.9	1.2	3.7	-0.5	1.9	0.2	0.8	0.9	-0.3	-1.5	-1.7	-0.1
Financial situation satisfaction	1.3	1.6	5.8	2.4	-0.8	0.5	-1.3	-1.3	1.0	0.0	1.2	1.3
Tinnitus: Yes, now most or all of the time	1.2	1.4	5.2	0.8	-1.3	-2.3	-1.8	-0.5	-0.2	1.0	0.9	-0.1
Commuting to job workplace: Public transport	3.4	4.0	8.2	-2.4	2.9	1.7	0.7	2.7	0.2	-2.5	-2.3	-0.1
Eye problems/disorders: Glaucoma	0.3	0.3	0.7	0.7	-0.7	-0.1	0.4	-0.4	0.2	0.8	0.8	0.6
Medication: Blood pressure	1.4	2.7	4.5	1.6	-2.0	-2.1	-0.3	-2.1	-1.1	1.8	2.1	0.7
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.2	0.4	-0.7	-0.3	-0.8	-0.8	-0.8	-1.1	-1.1	-0.3
Supplements: Fish oil (including cod liver oil)	1.5	2.0	4.3	-1.1	-0.2	-0.7	-1.1	0.9	-1.8	-2.1	-1.8	-1.9
High cholesterol (Self-reported)	1.5	2.6	4.6	1.9	-2.1	0.9	-1.8	-2.1	0.7	1.8	1.7	0.3
Medication: Bendroflumethiazide	0.9	1.4	3.0	0.5	-1.7	-1.5	0.3	-1.4	-1.7	1.0	0.9	-0.2
Medication: Paracetamol	1.6	2.4	6.8	2.6	-2.0	-0.1	-1.8	-2.0	-0.5	1.1	1.4	-0.8
Medication: Lisinopril	2.4	3.1	7.8	2.6	-2.8	1.2	-2.5	-1.4	0.3	1.0	1.4	-0.4
Medication: Atorvastatin	1.4	1.7	4.8	1.4	-2.2	0.2	-0.5	-1.7	0.1	1.5	1.8	-0.4
Illnesses of father: High blood pressure	0.6	0.8	3.9	0.1	-0.6	2.0	0.9	-1.3	-0.0	0.1	0.7	-0.2
Alcohol drinker status: Never	0.3	0.3	1.8	-0.4	-0.1	-1.3	-0.6	0.3	0.2	-0.1	-0.5	-0.2
Ever smoked	0.4	0.8	2.9	-0.1	1.2	1.7	0.0	-0.1	1.3	-0.7	-0.5	0.4
Basal metabolic rate	0.4	2.1	7.4	-2.5	1.2	-0.2	1.9	2.7	-0.4	0.3	-0.2	0.1
Leg fat percentage (left)	0.4	1.4	5.0	0.9	-2.2	1.0	-0.4	-1.9	-1.1	-0.4	-0.2	-0.9
Arm fat-free mass (left)	0.5	2.4	9.4	-2.5	1.8	0.0	1.7	3.1	0.0	0.3	-0.2	0.4
Number of operations (self-reported)	0.5	0.7	1.8	-1.0	1.3	-1.1	1.4	-0.3	-0.5	0.2	-0.4	-0.1
Average weekly beer plus cider intake	0.7	1.0	3.0	1.1	0.0	0.4	0.9	-0.5	0.6	1.3	1.7	1.4
Irritability	0.4	0.7	1.9	-0.2	0.2	-0.2	0.1	1.4	0.6	1.2	0.8	1.4
Risk taking	1.7	2.4	9.2	-2.0	1.8	-1.4	1.3	3.0	0.0	-0.5	-1.2	0.5
Ever had prostate specific antigen (PSA) test	0.6	0.7	2.3	-0.6	0.6	0.6	-0.1	0.1	-0.4	-1.1	-1.2	-1.5
Fractured/broken bones in last 5 years	0.8	1.0	3.6	-1.4	0.5	0.1	1.3	-0.2	-1.9	-0.6	-0.7	-0.6
Age started oral contraceptive pill	0.2	0.3	1.5	0.6	0.1	-1.2	-0.1	0.1	0.5	0.6	0.4	0.4
Diastolic blood pressure, automated reading	3.2	9.9	24.4	3.4	-4.9	-1.6	-1.2	-4.5	-2.9	2.6	3.3	-1.7
Ever depressed for a whole week	0.2	0.3	0.6	0.8	-0.2	0.6	0.6	-0.6	-0.2	-0.1	0.4	0.5
Unable to work because of sickness or disability	0.6	0.7	2.1	0.4	-0.5	-1.5	-0.5	-0.0	-0.5	1.4	1.2	0.3
Commuting to job workplace: Cycle	0.4	0.5	1.1	-0.2	0.8	-0.3	1.0	0.2	0.7	1.0	0.6	0.7
Myopia	0.4	0.6	1.8	0.5	-0.2	-1.3	0.9	-0.6	-0.6	0.5	1.1	0.8
Vascular/heart problems diagnosed by doctor	1.3	3.4	8.1	-2.0	2.9	1.3	0.6	2.7	1.5	-1.5	-2.2	-0.1
Cholesterol lowering medication	2.6	3.8	5.8	2.1	-1.6	1.4	-1.2	-2.0	2.2	2.4	2.2	2.1
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.4	-0.1	-0.6	0.5	-0.1	0.1	1.5	1.2	0.5	1.0
Pain experienced in last month	1.2	2.0	4.9	-1.6	1.7	2.2	2.0	1.0	0.2	-1.1	-0.6	-0.9
Supplements: Calcium	0.2	0.2	0.7	0.0	0.6	0.2	-0.0	-0.1	0.2	-0.9	-0.8	0.1
Basal cell carcinoma (self-reported)	0.4	0.5	1.1	-0.9	0.7	1.1	1.0	-0.0	0.3	0.5	-0.4	-0.5
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.3	0.4	-0.5	-0.7	0.0	-0.1	-0.1	1.1	1.1	0.3
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.2	-0.2	-0.2	-0.2	-0.4	-0.5	-0.1	0.3	-0.3	-0.4
Heart disease (siblings)	0.2	0.3	1.0	-0.4	0.7	-0.6	0.3	1.0	-0.1	-0.0	0.2	0.7
Alcohol drinker status: Previous	0.9	1.0	3.3	-0.4	0.1	-0.6	-1.6	0.4	-0.1	-1.8	-1.5	-0.5
Pack years of smoking	1.1	1.5	4.5	1.0	-0.8	-1.8	1.2	-0.2	0.6	0.6	1.5	2.1
Impedance of whole body	0.1	0.7	1.7	0.4	-0.7	-1.0	0.8	-1.3	-0.9	0.2	0.2	-1.1
Leg fat mass (left)	0.2	0.7	2.9	0.2	-1.7	0.9	0.3	-1.0	-0.8	0.3	0.2	-0.7
Arm predicted mass (left)	0.5	2.6	10.4	-2.6	1.9	0.0	1.7	3.2	-0.2	-0.1	-0.5	0.3