[Hub]/) : Traits : Heel T-Score : ← →

chr2:195,751,653-198,871,417

Best TWAS P=1.41e-12 · Best GWAS P=2.23e-14 conditioned to 0.000248

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous STK17B 0.16 0.04 enet 23 0.06 6.0e-06 -6.8 -5.8 7.7e-09 0.14 0.06 0.93 FALSE
2 GTEx Artery Aorta HECW2 0.16 0.03 enet 29 0.06 2.6e-04 -3.4 -5.6 2.2e-08 0.48 0.14 0.64 FALSE
3 GTEx Breast Mammary Tissue SLC39A10 0.10 0.08 lasso 3 0.04 4.2e-03 6.7 -6.7 1.7e-11 -0.01 0.14 0.36 TRUE
4 GTEx Esophagus Muscularis SLC39A10 0.07 0.03 lasso 3 0.02 2.4e-02 4.6 -5.1 2.8e-07 -0.10 0.12 0.15 FALSE
5 GTEx Lung ANKRD44 0.16 0.01 lasso 10 0.06 4.7e-05 -2.0 -6.7 2.9e-11 0.61 0.12 0.83 FALSE
6 GTEx Muscle Skeletal STK17B 0.15 0.06 lasso 4 0.05 5.0e-06 -6.9 -7.1 1.4e-12 -0.01 0.44 0.56 TRUE
7 GTEx Skin Sun Exposed Lower leg STK17B 0.20 0.14 lasso 6 0.17 1.2e-13 -6.8 -6.1 8.4e-10 0.06 0.53 0.47 FALSE
8 GTEx Skin Sun Exposed Lower leg HECW2 0.09 0.09 lasso 3 0.08 2.4e-07 -7.1 7.1 1.5e-12 -0.78 0.17 0.83 TRUE
9 GTEx Thyroid SLC39A10 0.08 0.06 lasso 3 0.05 1.5e-04 6.5 -6.6 4.5e-11 -0.01 0.21 0.50 FALSE
10 ROSMAP Brain Pre-frontal Cortex DNAH7 0.18 0.17 enet 25 0.22 1.7e-28 5.0 5.3 1.2e-07 0.15 1.00 0.00 FALSE
11 The Cancer Genome Atlas Breast Invasive Carcinoma DNAH7 0.04 0.01 blup 102 0.02 1.4e-05 4.3 -5.2 1.6e-07 -0.09 0.88 0.09 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma DNAH7 0.05 0.01 blup 102 0.03 1.0e-04 3.6 6.3 2.8e-10 0.02 0.05 0.90 FALSE
13 The Cancer Genome Atlas Pancreatic Adenocarcinoma DNAH7 0.08 0.05 lasso 2 0.05 3.2e-03 6.1 -6.5 5.6e-11 -0.07 0.04 0.57 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma DNAH7 0.15 0.17 lasso 6 0.14 5.2e-14 4.9 -5.2 2.1e-07 -0.10 1.00 0.00 FALSE