Best TWAS P=1.32e-11 · Best GWAS P=2.26e-11 conditioned to 0.0196
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | SDF4 | 0.06 | 0.05 | lasso | 2 | 0.06 | 1.9e-05 | -5.3 | 5.7 | 1.0e-08 | 0.05 | 0.01 | 0.97 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | SDF4 | 0.08 | 0.03 | enet | 12 | 0.04 | 8.0e-04 | -5.3 | 5.2 | 1.9e-07 | 0.03 | 0.01 | 0.98 | FALSE |
| 3 | METSIM | Adipose | MMEL1 | 0.07 | 0.08 | lasso | 4 | 0.08 | 5.5e-12 | -5.3 | 5.2 | 1.5e-07 | 0.28 | 0.87 | 0.13 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | C1orf93 | 0.06 | 0.04 | blup | 38 | 0.04 | 1.2e-04 | -5.3 | 5.5 | 3.4e-08 | 0.27 | 0.48 | 0.09 | FALSE |
| 5 | The Cancer Genome Atlas | Soft Tissue Sarcoma | MMEL1 | 0.05 | 0.01 | blup | 38 | 0.02 | 1.7e-02 | 4.6 | 6.8 | 1.3e-11 | 0.70 | 0.01 | 0.64 | TRUE |
| 6 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | MMEL1 | 0.13 | 0.14 | lasso | 6 | 0.13 | 2.2e-05 | -5.3 | 5.3 | 9.0e-08 | 0.28 | 0.40 | 0.12 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | MMEL1 | 0.05 | 0.07 | blup | 38 | 0.07 | 2.1e-07 | -5.3 | 5.5 | 4.9e-08 | 0.31 | 0.88 | 0.12 | FALSE |