[Hub]/) : Traits : Hypothyroidism (self reported) : →

chr1:752,566-3,261,925

Best TWAS P=1.32e-11 · Best GWAS P=2.26e-11 conditioned to 0.0196

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	The Cancer Genome Atlas	Soft Tissue Sarcoma	MMEL1	0.05	0.01	blup	38	0.02	1.7e-02	4.6	6.8	1.3e-11	0.70	0.01	0.64	TRUE
1	GTEx	Artery Tibial	SDF4	0.06	0.05	lasso	2	0.06	1.9e-05	-5.3	5.7	1.0e-08	0.05	0.01	0.97	TRUE
4	The Cancer Genome Atlas	Prostate Adenocarcinoma	C1orf93	0.06	0.04	blup	38	0.04	1.2e-04	-5.3	5.5	3.4e-08	0.27	0.48	0.09	FALSE
7	The Cancer Genome Atlas	Thyroid Carcinoma	MMEL1	0.05	0.07	blup	38	0.07	2.1e-07	-5.3	5.5	4.9e-08	0.31	0.88	0.12	FALSE
6	The Cancer Genome Atlas	Testicular Germ Cell Tumors	MMEL1	0.13	0.14	lasso	6	0.13	2.2e-05	-5.3	5.3	9.0e-08	0.28	0.40	0.12	FALSE
3	METSIM	Adipose	MMEL1	0.07	0.08	lasso	4	0.08	5.5e-12	-5.3	5.2	1.5e-07	0.28	0.87	0.13	FALSE
2	GTEx	Cells Transformed fibroblasts	SDF4	0.08	0.03	enet	12	0.04	8.0e-04	-5.3	5.2	1.9e-07	0.03	0.01	0.98	FALSE