TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Hypothyroidism (self reported)
:
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chr1:7,792,411-9,190,254
Best TWAS P=1.61e-07 · Best GWAS P=2.15e-07 conditioned to 1
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Thyroid
RP5-1115A15.1
0.09
0.12
lasso
2
0.09
1.5e-07
5.2
-5.2
1.6e-07
-0.99
0
1.00
TRUE
1
GTEx
Lung
RP5-1115A15.1
0.05
0.08
lasso
1
0.07
1.0e-05
5.2
-5.2
2.2e-07
-1.00
0
0.99
FALSE