TWAS hub - MMEL1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	METSIM	Adipose	0.0673	0.0184	5.4e-09	0.085	0.062	0.080	0.072	0.080	1.2e-12	1.1e-09	5.7e-12	5.4e-11	5.5e-12
2	YFS	Blood	0.0429	0.0108	1.1e-13	0.052	0.049	0.053	0.051	0.054	1.1e-16	9.2e-16	9.5e-17	3.3e-16	4.6e-17
3	TCGA	Breast Invasive Carcinoma	0.0199	0.0124	8.3e-06	0.020	0.026	0.019	NA	0.022	4.6e-05	3.3e-06	6.4e-05	NA	1.6e-05
4	TCGA	Colon Adenocarcinoma	0.0380	0.0250	2.3e-03	0.048	0.036	0.044	NA	0.036	9.3e-04	3.7e-03	1.5e-03	NA	3.8e-03
5	TCGA	Lung Adenocarcinoma	0.0471	0.0300	2.8e-06	0.031	0.050	0.044	NA	0.039	1.4e-04	1.6e-06	6.8e-06	NA	2.1e-05
6	TCGA	Lung Squamous Cell Carcinoma	0.0343	0.0300	3.3e-03	0.011	0.009	0.021	NA	0.010	1.9e-02	2.7e-02	1.8e-03	NA	2.3e-02
7	TCGA	Prostate Adenocarcinoma	0.1047	0.0545	2.5e-13	0.121	0.141	0.154	NA	0.139	1.4e-12	1.6e-14	8.5e-16	NA	2.2e-14
8	TCGA	Soft Tissue Sarcoma	0.0520	0.0340	4.8e-03	0.008	0.022	0.010	NA	0.011	1.1e-01	1.7e-02	7.4e-02	NA	6.8e-02
9	TCGA	Testicular Germ Cell Tumors	0.1300	0.0850	2.6e-04	0.139	0.100	0.123	NA	0.132	1.3e-05	2.1e-04	4.3e-05	NA	2.2e-05
10	TCGA	Thyroid Carcinoma	0.0450	0.0240	3.9e-07	0.072	0.071	0.064	NA	0.069	1.5e-07	2.1e-07	7.0e-07	NA	3.0e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Rheumatoid Arthritis	17.3	23.9	35.4	5.3	3.9	4.1	4.8	4.5	4.8	4.4	6.0	5.3	5.4
Ulcerative Colitis	15.0	21.8	31.5	4.5	5.0	5.5	4.3	5.5	4.4	5.6	2.1	4.4	4.4
Ulcerative Colitis (UC)	14.6	27.5	38.2	5.1	5.6	6.0	4.9	6.2	5.3	5.7	2.6	5.1	5.0
Primary Biliary Cirrhosis	11.5	16.4	19.4	-4.3	-3.5	-3.8	-4.1	-4.1	-4.1	-3.6	-4.2	-4.3	-4.4
Hypothyroidism/myxoedema (self-reported)	11.5	22.5	36.2	5.0	4.3	4.1	5.1	4.0	4.1	4.0	6.0	5.1	5.3
Medication: Levothyroxine sodium	11.2	19.0	31.2	4.6	4.2	3.6	4.7	3.6	4.0	3.3	5.6	4.6	4.8
Hypothyroidism (self reported)	10.5	24.0	45.8	5.2	4.3	3.8	5.1	3.8	4.5	3.8	6.8	5.3	5.5
Pain type(s) experienced in last month: Hip pain	8.2	10.4	13.6	-3.2	-3.4	-3.5	-3.0	-3.7	-3.3	-3.3	-2.0	-3.2	-3.2
Body Mass Index (BMI) (2010)	5.8	7.9	12.0	-2.6	-3.3	-3.5	-2.6	-3.4	-2.7	-3.4	-0.7	-2.5	-2.5
Bipolar Disorder or Schizophrenia	5.5	13.5	15.7	-3.9	-3.5	-3.5	-3.4	-3.8	-4.0	-3.3	-3.4	-3.9	-3.9
Prospective memory result	5.4	6.6	9.1	-2.6	-2.2	-2.0	-2.9	-2.6	-2.9	-1.6	-3.0	-2.5	-2.9
Schizophrenia (2018)	4.8	10.0	11.8	-3.4	-3.4	-3.1	-2.9	-3.1	-3.3	-3.0	-2.7	-3.3	-3.2
Severe depression (siblings)	4.3	4.8	7.7	-2.1	-2.6	-2.5	-2.1	-2.8	-2.4	-1.9	-0.8	-2.0	-2.1
Medication: Ventolin 100micrograms inhaler	4.1	5.3	8.5	2.3	2.2	2.9	2.0	2.8	2.1	2.5	1.1	2.4	2.2
Wears glasses or contact lenses	4.1	4.7	9.4	-2.3	-2.1	-1.4	-2.1	-1.9	-3.1	-0.9	-2.6	-2.3	-2.3
Ever used hormone-replacement therapy (HRT)	3.9	4.9	6.9	2.3	2.4	2.3	2.6	2.4	1.9	1.9	1.8	2.1	2.4
Sensitivity / hurt feelings	3.8	6.5	12.0	-2.8	-2.1	-1.6	-2.3	-2.4	-3.1	-1.2	-3.5	-2.8	-2.8
Breastfed as a baby	3.8	4.7	6.8	-2.3	-2.3	-2.1	-2.6	-1.9	-1.8	-1.7	-2.4	-2.2	-2.4
Irritable Bowel Disease (IBD)	3.7	8.7	15.0	2.8	3.3	3.8	2.4	3.9	2.8	3.4	0.2	2.8	2.5
Type 2 Diabetes (T2D) (2012)	3.7	4.2	6.0	2.1	2.5	1.9	2.3	1.8	2.1	1.6	2.0	2.0	2.1
Financial difficulties in last 2 years	3.6	4.8	6.6	-2.3	-2.2	-1.9	-2.1	-2.2	-2.6	-1.6	-2.1	-2.4	-2.3
Leg fat percentage (left)	3.6	13.2	18.9	-3.6	-4.4	-4.1	-3.1	-4.0	-3.7	-4.2	-1.5	-3.6	-3.3
Blood clot in the leg (DVT)	3.4	4.4	6.1	2.2	1.9	1.9	2.5	1.9	2.2	1.6	2.3	2.2	2.3
Deep venous thrombosis (DVT) (self-reported)	3.4	4.4	6.2	2.2	1.9	1.9	2.5	1.9	2.1	1.7	2.3	2.2	2.3
Townsend deprivation index at recruitment	3.3	4.6	8.2	-2.2	-2.1	-1.7	-1.7	-2.3	-2.9	-1.7	-2.1	-2.3	-2.2
Respiratory disease	3.2	7.0	11.8	2.6	2.7	3.4	2.2	3.4	2.4	3.0	0.6	2.6	2.4
Leg fat mass (left)	3.2	12.5	19.1	-3.3	-4.4	-4.3	-2.9	-4.1	-3.4	-4.4	-0.7	-3.3	-3.0
Blood Eosinophil Count	3.1	23.8	41.2	4.7	4.8	6.4	4.1	6.2	3.7	6.2	1.1	4.8	4.5
Other serious medical condition/disability diagnosed by doctor	3.1	4.0	5.9	2.0	2.0	1.7	2.2	1.8	1.7	1.7	2.4	2.0	2.2
Leg fat percentage (right)	3.1	11.2	16.6	-3.3	-4.1	-3.7	-2.8	-3.6	-3.5	-4.0	-1.5	-3.3	-3.0
Asthma (self-reported)	3.1	6.2	11.1	2.5	2.4	3.3	1.8	3.3	2.0	3.1	0.5	2.6	2.3
Diabetes (self-reported)	2.9	4.4	9.4	2.2	1.4	1.5	2.5	1.7	1.8	1.6	3.1	2.2	2.4
Leg fat mass (right)	2.8	11.0	17.2	-3.1	-4.1	-4.0	-2.7	-3.9	-3.2	-4.2	-0.6	-3.1	-2.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.8	3.3	4.8	1.8	1.7	1.9	1.9	2.0	2.2	1.8	1.2	1.7	1.8
Lupus	2.7	4.1	5.2	2.1	1.6	2.1	2.2	2.0	1.8	1.7	2.2	2.2	2.3
Schizophrenia (2014)	2.7	6.0	8.6	-2.7	-2.6	-1.9	-2.3	-2.0	-2.9	-1.6	-2.9	-2.7	-2.6
Taking other prescription medications	2.7	4.2	5.2	2.3	1.9	2.1	1.9	1.9	1.3	2.2	2.3	2.3	2.2
Body fat percentage	2.7	10.7	15.9	-3.1	-3.8	-3.8	-2.8	-3.7	-3.3	-4.0	-1.1	-3.1	-2.9
Diabetes (father)	2.6	3.3	4.4	-1.9	-1.8	-1.7	-1.7	-1.9	-2.1	-1.4	-1.7	-2.0	-1.9
Trunk fat percentage	2.6	10.5	15.6	-3.1	-3.7	-3.8	-2.9	-3.7	-3.1	-4.0	-1.2	-3.1	-3.0
Asthma	2.6	5.0	9.4	2.2	2.1	3.1	1.5	3.0	1.8	2.8	0.2	2.3	1.9
Medication: Amlodipine	2.6	3.7	7.3	-2.1	-1.7	-1.5	-1.4	-2.2	-2.7	-1.1	-1.8	-2.1	-2.0
BMI	2.5	14.3	22.4	-3.4	-4.7	-4.7	-2.9	-4.6	-4.1	-4.6	-0.1	-3.4	-3.0
Lung FEV1/FVC ratio	2.5	12.4	17.6	-3.6	-4.2	-4.0	-3.1	-3.5	-3.5	-4.0	-1.9	-3.7	-3.2
Chronotype (morning person)	2.5	5.8	8.1	-2.5	-2.8	-2.7	-2.2	-2.8	-2.2	-2.1	-1.5	-2.5	-2.4
Trunk fat mass	2.5	10.8	16.5	-3.1	-3.9	-4.0	-2.9	-3.9	-3.1	-4.1	-0.7	-3.0	-2.9
Whole body fat mass	2.5	10.3	16.1	-3.0	-3.9	-3.9	-2.6	-3.8	-3.1	-4.0	-0.4	-3.0	-2.7
Bipolar Disorder (2018)	2.4	3.8	4.8	-2.1	-1.4	-1.7	-1.9	-2.2	-2.2	-1.5	-2.0	-2.1	-2.2
Fractured/broken bones in last 5 years	2.4	3.1	3.7	1.9	1.9	1.5	1.9	1.7	1.7	1.4	1.9	1.8	1.9
Mean Putamen Volume	2.3	2.7	5.5	-1.7	-1.5	-1.1	-1.5	-1.6	-2.4	-1.1	-1.7	-1.7	-1.7
Number of incorrect matches in round	2.3	3.8	5.8	-2.0	-1.8	-1.5	-2.2	-1.9	-2.4	-1.1	-2.2	-1.9	-2.1
Pulse rate, automated reading	2.3	7.5	10.5	2.9	2.7	2.6	2.4	2.9	3.2	2.4	2.4	3.0	2.8
Diabetes diagnosed by doctor	2.3	3.9	6.2	2.0	1.3	1.7	2.2	1.8	1.7	1.8	2.5	2.1	2.3
Nervous feelings	2.2	4.0	9.0	-2.1	-1.6	-1.3	-2.1	-1.8	-1.9	-1.3	-3.0	-2.1	-2.3
Illnesses of mother	2.2	2.8	3.4	1.7	1.9	1.8	1.7	1.9	1.3	1.9	1.3	1.6	1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	2.2	3.4	6.2	-2.0	-1.9	-1.6	-1.8	-1.8	-2.5	-0.9	-1.7	-2.1	-1.9
Knee pain experienced in last month	2.2	3.4	5.7	-1.5	-2.2	-2.2	-1.1	-2.3	-2.2	-2.4	0.0	-1.6	-1.4
Mother’s age at death	2.2	2.7	6.2	1.5	2.5	1.8	1.9	1.6	1.2	1.5	0.9	1.3	1.6
Waist circumference	2.1	7.6	14.2	-2.5	-3.5	-3.5	-1.9	-3.2	-2.6	-3.8	0.0	-2.5	-2.1
Long-standing illness, disability or infirmity	2.1	3.2	4.7	2.0	1.3	1.9	1.8	1.6	0.8	2.2	2.0	2.0	2.0
Body mass index (BMI)	2.0	8.5	16.6	-2.5	-3.7	-3.8	-1.8	-3.6	-2.7	-4.1	0.6	-2.5	-2.1
Arm fat mass (left)	2.0	8.2	14.8	-2.5	-3.6	-3.7	-2.1	-3.5	-2.7	-3.8	0.3	-2.5	-2.2
Hearing difficulty/problems: Yes	1.9	2.8	4.2	1.7	0.8	1.6	2.1	1.7	1.6	1.6	1.7	1.7	1.9
Had other major operations	1.9	2.3	3.2	1.5	1.6	1.7	1.7	1.4	1.3	1.8	1.2	1.5	1.5
Fluid intelligence score	1.9	3.9	4.7	2.0	2.1	2.1	2.2	2.0	1.6	2.0	1.6	1.9	2.0
Exposure to tobacco smoke outside home	1.9	2.5	4.5	-1.4	-2.1	-2.0	-1.5	-1.9	-1.2	-1.9	-0.3	-1.3	-1.3
Medication for hormone replacement therapy	1.8	2.0	3.1	1.4	1.6	1.8	1.6	1.4	0.6	1.7	1.0	1.3	1.5
Allergy	1.8	4.0	9.5	-1.2	-1.9	-3.1	-1.3	-2.9	-1.4	-2.7	2.1	-1.3	-1.0
Arm fat mass (right)	1.8	7.3	13.8	-2.3	-3.3	-3.5	-1.9	-3.3	-2.5	-3.7	0.3	-2.3	-2.0
Arm fat percentage (left)	1.8	7.1	11.6	-2.4	-3.2	-3.3	-2.0	-3.3	-2.8	-3.4	0.1	-2.4	-2.1
Number of self-reported non-cancer illnesses	1.8	3.0	5.0	1.8	1.3	1.8	2.1	1.3	0.5	1.8	2.2	1.8	2.0
Number of operations (self-reported)	1.8	2.7	4.8	1.5	1.7	2.0	2.2	1.7	1.1	1.7	1.1	1.3	1.7
Weight	1.7	8.3	16.3	-2.5	-3.6	-3.9	-2.0	-3.5	-2.3	-4.0	0.4	-2.5	-2.1
Comparative body size at age 10	1.7	4.8	9.5	-1.9	-2.3	-3.1	-2.0	-2.6	-1.5	-3.0	-0.0	-1.9	-1.8
Handedness (chirality/laterality): Left-handed	1.7	2.1	4.5	-1.5	-1.0	-0.9	-1.5	-1.3	-1.8	-0.7	-2.1	-1.4	-1.6
Ever depressed for a whole week	1.7	2.1	4.5	1.4	1.4	1.7	1.0	1.7	1.2	2.1	0.5	1.4	1.3
Heart attack/myocardial infarction (self-reported)	1.7	2.2	5.4	-1.4	-1.9	-1.3	-1.6	-1.5	-2.3	-0.8	-0.7	-1.3	-1.3
Alzheimer’s Disease (including proxy)	1.6	2.4	3.7	-1.4	-1.6	-1.9	-1.9	-1.8	-1.2	-1.5	-0.9	-1.4	-1.7
Fasting Glucose	1.6	1.9	3.7	1.6	0.8	0.7	1.2	1.3	1.8	0.9	1.9	1.7	1.5
Eye problems/disorders: Diabetes related eye disease	1.5	1.6	3.5	1.2	1.1	1.8	1.2	1.3	0.3	1.9	0.6	1.2	1.2
Maternal smoking around birth	1.5	2.2	3.8	1.3	1.2	1.5	1.7	1.9	1.9	1.4	0.7	1.3	1.5
Heart attack	1.5	2.0	4.8	-1.3	-1.8	-1.3	-1.6	-1.5	-2.2	-0.7	-0.6	-1.3	-1.2
Medication: Ramipril	1.5	1.9	5.2	-1.4	-1.6	-1.0	-0.8	-1.5	-2.3	-1.0	-1.1	-1.5	-1.2
Arm fat percentage (right)	1.5	5.9	10.4	-2.1	-2.9	-3.0	-1.8	-3.0	-2.5	-3.2	0.1	-2.1	-1.9
Qualifications: O levels/GCSEs or equivalent	1.5	2.4	3.5	-1.6	-1.4	-1.9	-1.6	-1.8	-1.2	-1.7	-0.9	-1.5	-1.6
Illnesses of father: High blood pressure	1.5	1.9	3.1	1.4	1.5	1.7	1.0	1.7	1.0	1.8	0.5	1.4	1.3
Lung FVC	1.4	6.9	9.3	2.5	3.0	2.3	3.0	2.7	3.0	2.0	2.4	2.3	2.8
Alcohol usually taken with meals	1.4	2.2	3.2	-1.6	-1.0	-1.4	-1.7	-1.7	-1.5	-0.7	-1.6	-1.6	-1.8
Hip circumference	1.4	6.1	11.0	-2.2	-3.0	-3.2	-2.0	-3.0	-2.1	-3.3	-0.1	-2.2	-2.0
Pulse wave peak to peak time	1.4	1.6	3.4	1.1	1.4	1.6	0.6	1.9	1.4	1.4	-0.5	1.2	0.9
Smoking status: Previous	1.4	2.0	3.2	1.5	1.8	1.5	1.5	1.4	1.1	1.0	1.2	1.4	1.6
Breast cancer (self-reported)	1.4	1.7	2.7	1.2	1.3	1.5	1.3	1.5	1.4	1.6	0.6	1.2	1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.4	2.9	3.9	-1.9	-1.5	-1.5	-1.5	-1.5	-1.5	-1.5	-1.9	-2.0	-1.8
Age started oral contraceptive pill	1.4	1.7	3.1	-1.4	-1.4	-1.7	-0.7	-1.3	-1.0	-1.8	-0.7	-1.6	-1.2
Alzheimer’s Disease (in mother)	1.3	1.5	2.6	-1.1	-1.2	-1.5	-1.5	-1.6	-1.1	-1.1	-0.6	-1.0	-1.3
Crohns Disease (2017)	1.3	2.8	8.8	-1.6	-1.4	-0.9	-1.9	-0.9	-1.4	-1.2	-3.0	-1.6	-1.9
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	3.1	1.1	1.3	1.6	1.1	1.8	1.2	1.1	-0.0	1.0	1.1
Qualifications: A levels/AS levels or equivalent	1.3	2.9	4.9	-1.9	-1.2	-1.3	-1.8	-1.4	-1.9	-1.1	-2.2	-1.9	-1.9
Depression (self-reported)	1.3	1.5	3.4	-1.3	-1.0	-0.5	-1.2	-0.8	-1.8	0.5	-1.8	-1.3	-1.3
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	2.9	-1.2	-1.5	-1.5	-0.8	-1.5	-1.3	-1.7	-0.3	-1.4	-1.1
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.5	2.1	1.3	1.4	1.3	1.0	1.3	1.4	1.2	0.9	1.3	1.2
Vascular/heart problems diagnosed by doctor	1.3	3.4	5.2	1.8	2.1	2.0	1.9	2.3	2.3	1.3	0.8	1.8	1.8
Worry (Nagel 2018)	1.2	2.5	10.5	-1.5	-0.6	-0.2	-1.7	-0.8	-1.6	0.3	-3.2	-1.5	-1.8
HbA1C	1.2	1.3	2.0	1.1	1.4	1.1	1.3	1.2	1.4	0.9	0.8	0.9	1.2
Hand grip strength (right)	1.2	3.4	4.7	-2.1	-1.9	-1.9	-1.7	-1.9	-1.6	-1.3	-1.7	-2.2	-2.0
Ever unenthusiastic/disinterested for a whole week	1.2	1.4	5.1	0.9	1.0	1.6	0.8	1.4	0.5	2.2	-0.0	1.0	0.9
Father’s age at death	1.2	1.6	4.8	1.3	2.2	1.3	0.6	1.1	1.0	1.6	0.4	1.2	0.9
Pulse wave Arterial Stiffness index	1.2	1.4	3.0	-1.0	-1.4	-1.6	-0.5	-1.7	-1.2	-1.4	0.6	-1.1	-0.8
Gout (self-reported)	1.2	1.7	3.1	-1.3	-1.3	-1.6	-0.8	-1.8	-1.4	-1.4	-0.3	-1.4	-1.2
Angina (self-reported)	1.2	1.5	2.2	-1.3	-1.4	-1.3	-1.0	-1.1	-0.9	-1.5	-1.1	-1.4	-1.2
Had major operations	1.2	1.4	2.7	-1.4	-1.0	-0.6	-1.1	-0.9	-1.6	-0.3	-1.6	-1.4	-1.2
Allergy or Eczema	1.1	2.9	7.5	0.6	1.5	2.5	0.7	2.5	0.8	2.3	-2.7	0.6	0.4
Ever had hysterectomy (womb removed)	1.1	1.2	2.1	0.9	1.4	1.4	1.4	1.2	1.1	1.0	0.2	0.8	1.0
Hayfever, allergic rhinitis or eczema	1.1	2.5	10.6	0.2	1.3	2.2	0.4	2.0	0.5	1.7	-3.2	0.1	-0.1
Multivitamins +/- minerals	1.1	1.4	1.8	-1.3	-1.4	-1.1	-1.1	-1.1	-0.9	-1.3	-1.3	-1.3	-1.2
Time employed in main current job	1.1	1.3	3.0	1.2	0.5	0.8	1.1	0.6	1.0	1.1	1.7	1.3	1.2
Average weekly champagne plus white wine intake	1.1	1.5	2.7	1.3	1.3	0.8	1.2	1.1	1.6	0.7	1.4	1.3	1.3
Supplements: Calcium	1.1	1.2	2.3	1.0	0.8	1.5	1.0	1.4	0.9	1.5	-0.0	1.0	0.9
Number of treatments/medications taken	1.0	1.7	3.1	1.3	1.3	1.8	1.4	1.2	0.0	1.6	1.1	1.3	1.4
Angina	1.0	1.3	2.2	-1.2	-1.3	-1.3	-1.0	-1.0	-0.7	-1.5	-1.1	-1.3	-1.2
Relative age voice broke	1.0	1.5	3.5	-1.4	-0.8	-0.9	-1.1	-0.8	-0.8	-1.1	-1.9	-1.5	-1.4
Loud music exposure frequency	1.0	1.1	2.3	1.0	1.2	1.0	1.5	0.8	1.0	0.4	1.2	1.0	1.2
Number of full brothers	1.0	1.3	3.9	-1.2	-0.9	-1.2	-0.2	-0.9	-0.9	-2.0	-0.8	-1.4	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	2.1	-1.3	-1.3	-0.9	-1.2	-0.9	-1.4	0.1	-1.2	-1.3	-1.1
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.2	3.6	-1.2	-0.9	-0.4	-1.0	-0.7	-1.3	0.2	-1.9	-1.1	-1.2
Suffer from ‘nerves’	1.0	1.6	2.7	-1.3	-0.9	-1.0	-1.3	-1.4	-1.6	-0.8	-1.5	-1.3	-1.4
Myopia	1.0	1.5	2.4	-1.4	-0.7	-1.2	-1.0	-1.5	-1.6	-0.6	-1.1	-1.5	-1.4
Major Depression (MDD)	0.9	1.1	2.1	0.0	0.0	1.4	1.3	1.3	1.3	1.4	0.2	1.0	1.0
Frequency of depressed mood in last 2 weeks	0.9	1.2	3.6	-1.2	-0.8	-0.3	-0.9	-0.6	-1.6	0.2	-1.9	-1.3	-1.1
High blood pressure	0.9	2.4	4.0	-1.5	-1.7	-1.7	-1.5	-2.0	-2.0	-1.1	-0.5	-1.5	-1.5
Stomach or abdominal pain in last month	0.9	1.1	1.9	1.0	1.2	1.4	0.6	1.3	1.1	1.1	0.0	1.1	0.8
Past tobacco smoking	0.9	1.6	2.4	-1.3	-1.3	-0.9	-1.5	-1.3	-1.6	-0.5	-1.3	-1.2	-1.4
Illnesses of siblings	0.9	1.3	2.0	1.0	1.4	1.3	1.4	1.3	0.9	1.1	0.5	0.9	1.1
Exposure to tobacco smoke at home	0.9	1.0	1.6	1.1	1.3	0.8	0.8	0.9	1.2	0.5	1.0	1.1	1.0
Headache pain in last month	0.9	1.6	3.6	1.4	1.9	1.4	1.3	1.0	0.8	1.1	0.8	1.4	1.2
Arm fat-free mass (right)	0.9	4.7	9.8	-1.8	-3.0	-3.1	-1.2	-2.6	-1.3	-3.1	0.9	-1.8	-1.4
Eye problems/disorders: None of the above	0.9	1.0	2.0	-1.1	-1.0	-1.1	-0.9	-0.8	-0.8	-1.4	-0.7	-1.1	-0.9
Medication: Allopurinol	0.9	1.2	2.2	-1.1	-1.2	-1.2	-0.7	-1.5	-1.3	-0.9	-0.2	-1.2	-1.0
Arm predicted mass (right)	0.9	4.6	9.9	-1.7	-3.0	-3.1	-1.1	-2.6	-1.2	-3.0	1.0	-1.7	-1.3
Family relationship satisfaction	0.9	1.1	2.2	0.8	1.1	1.5	1.1	1.4	0.8	1.1	-0.1	0.8	0.9
Illnesses of siblings: Diabetes	0.9	1.0	2.2	-0.8	-1.5	-1.5	-0.9	-1.1	-0.6	-1.4	0.2	-0.7	-0.7
Alcohol drinker status: Never	0.9	1.1	2.5	0.8	1.2	1.6	1.1	1.3	0.5	1.5	-0.1	0.8	0.9
Ever smoked	0.9	1.6	2.9	1.2	1.2	0.8	1.7	1.1	1.5	0.8	1.5	1.1	1.4
Coronary Artery Disease (CAD)	0.8	0.9	1.5	0.0	0.5	1.0	1.1	1.2	1.1	0.9	1.1	1.0	1.2
Crohns Disease (2012)	0.8	1.2	4.5	-1.0	-0.9	-0.2	-1.0	-0.4	-1.5	0.1	-2.1	-1.0	-1.1
Blood Platelet Count	0.8	9.2	13.1	3.1	3.0	2.6	3.3	2.8	3.6	2.1	3.3	3.1	3.2
Cardiovascular Disease	0.8	2.5	3.6	-1.5	-1.9	-1.8	-1.7	-1.9	-1.7	-1.4	-0.6	-1.4	-1.5
Hand grip strength (left)	0.8	2.0	2.9	-1.5	-1.4	-1.7	-1.6	-1.6	-1.1	-1.2	-1.0	-1.6	-1.5
Chronic bronchitis/emphysema (father)	0.8	0.9	1.6	-1.2	-1.2	-0.7	-0.5	-0.7	-1.0	-0.7	-1.1	-1.3	-0.9
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	1.5	-1.0	-1.0	-0.7	-1.2	-0.7	-1.2	-0.7	-1.2	-0.9	-1.1
Medication: Blood pressure	0.8	1.3	4.5	-1.1	-1.4	-0.8	-0.9	-1.2	-2.1	-0.7	-0.6	-1.0	-0.9
Medication: Seretide 50 evohaler	0.8	1.0	2.9	0.8	0.9	1.5	0.7	1.2	0.4	1.7	-0.2	0.8	0.8
Commuting to job workplace: Public transport	0.8	1.0	1.5	-1.0	-1.1	-1.2	-1.0	-1.2	-1.0	-0.8	-0.2	-1.0	-0.9
Basal metabolic rate	0.8	4.3	9.1	-1.6	-2.8	-3.0	-1.2	-2.6	-1.2	-3.0	1.1	-1.6	-1.2
Unable to work because of sickness or disability	0.8	1.0	2.4	-0.7	-1.0	-1.3	-1.1	-1.2	-0.9	-1.5	0.1	-0.7	-0.8
Arm predicted mass (left)	0.8	4.3	9.5	-1.6	-2.9	-3.0	-1.2	-2.4	-1.1	-3.1	0.8	-1.6	-1.3
Breast Cancer	0.7	1.6	2.3	-1.3	-1.2	-1.2	-1.3	-1.1	-1.0	-1.2	-1.5	-1.3	-1.4
Prostate Cancer	0.7	1.0	2.1	-1.0	-1.2	-0.8	-0.9	-1.0	-1.5	-0.8	-0.9	-1.0	-1.0
LDL Cholesterol	0.7	1.1	1.8	-1.1	-0.7	-0.9	-1.1	-1.0	-0.8	-1.0	-1.3	-1.0	-1.2
Age when periods started (menarche)	0.7	1.6	3.2	-1.2	-0.9	-1.2	-1.5	-1.8	-1.4	-0.7	-0.8	-1.2	-1.5
Qualifications: CSEs or equivalent	0.7	0.9	2.2	-0.7	-0.9	-1.3	-0.8	-1.2	-0.8	-1.5	0.5	-0.6	-0.6
Lung cancer (father)	0.7	0.8	1.5	-0.8	-0.9	-0.8	-1.0	-0.7	-0.5	-1.2	-1.0	-0.7	-0.9
Worry too long after embarrassment	0.7	1.1	1.5	-1.0	-1.1	-1.2	-1.1	-1.2	-0.7	-1.2	-0.8	-1.0	-1.1
Leg fat-free mass (right)	0.7	3.8	8.9	-1.4	-2.4	-3.0	-1.1	-2.6	-0.9	-2.7	1.5	-1.3	-1.1
Loneliness, isolation	0.7	1.0	2.2	0.8	0.9	1.2	1.2	1.5	0.9	1.0	0.1	0.7	1.0
Eye problems/disorders: Cataract	0.7	0.8	1.0	-0.9	-0.8	-0.9	-0.8	-1.0	-0.7	-0.7	-0.8	-0.9	-1.0
Mouth/teeth dental problems: Mouth ulcers	0.7	1.2	1.8	1.1	1.0	1.4	1.3	0.9	0.1	1.1	1.1	1.1	1.2
Leg predicted mass (right)	0.7	3.8	9.0	-1.4	-2.4	-3.0	-1.1	-2.6	-1.0	-2.7	1.5	-1.3	-1.1
Tinnitus: Yes, now most or all of the time	0.7	0.8	1.3	0.9	1.0	0.8	1.1	0.9	1.1	0.6	0.8	0.9	1.0
Arm fat-free mass (left)	0.7	3.7	8.1	-1.5	-2.7	-2.8	-1.1	-2.3	-1.0	-2.9	0.8	-1.5	-1.2
Ever had prostate specific antigen (PSA) test	0.7	0.8	1.4	1.0	0.8	0.9	0.5	0.8	0.3	1.2	1.1	1.1	0.9
HDL Cholesterol	0.6	1.1	2.4	0.9	1.5	1.1	1.1	1.2	1.3	0.8	0.3	0.7	0.9
Triglycerides	0.6	1.0	2.7	-0.9	-1.6	-1.0	-1.2	-0.9	-0.9	-0.9	-0.7	-0.5	-0.9
Leg fat-free mass (left)	0.6	3.4	8.0	-1.2	-2.3	-2.8	-1.0	-2.4	-0.8	-2.7	1.5	-1.2	-1.0
Average weekly fortified wine intake	0.6	0.7	1.2	-0.9	-1.1	-0.7	-0.6	-0.7	-1.0	-0.4	-0.9	-0.9	-0.8
Leg predicted mass (left)	0.6	3.3	7.8	-1.2	-2.3	-2.8	-0.9	-2.4	-0.8	-2.7	1.6	-1.2	-0.9
Had menopause	0.6	0.8	1.9	0.8	1.0	0.9	1.4	1.0	0.8	0.4	0.7	0.6	1.0
Pulse rate	0.6	0.9	1.4	1.0	1.2	1.0	0.6	1.0	0.9	1.1	0.8	1.1	0.9
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.6	2.5	-0.8	-0.3	-0.1	-1.1	-0.4	-0.6	0.4	-1.6	-0.7	-0.9
Shortness of breath walking on level ground	0.6	0.7	1.7	-0.8	-1.2	-0.6	-0.8	-0.7	-1.3	-0.3	-0.9	-0.8	-0.8
Medication: Omeprazole	0.6	0.7	1.4	-0.6	-0.6	-1.1	-0.9	-1.2	-0.8	-1.2	0.2	-0.6	-0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.0	-0.8	-0.3	-0.8	-0.6	-1.0	-0.9	-1.0	-0.8	-0.9	-0.9
Qualifications: nursing, teaching	0.6	1.0	2.1	-1.1	-0.5	-0.7	-1.3	-0.7	-0.8	-0.7	-1.4	-1.0	-1.1
Medication: Aspirin	0.6	0.8	1.8	-1.0	-0.8	-0.4	-0.7	-0.6	-1.3	-0.1	-1.3	-1.0	-0.9
Supplements: Fish oil (including cod liver oil)	0.6	0.7	2.4	-0.9	-0.5	-0.5	-0.8	-0.5	-0.5	-0.8	-1.5	-0.9	-1.0
Medication: Bendroflumethiazide	0.6	0.9	1.5	-0.8	-1.0	-1.0	-1.1	-1.2	-1.2	-0.6	-0.4	-0.8	-1.0
Medication: Atorvastatin	0.6	0.8	1.6	-0.8	-1.1	-0.6	-1.2	-0.8	-1.2	0.2	-0.8	-0.7	-0.9
Heart disease (siblings)	0.6	0.8	1.6	-0.7	-0.8	-1.1	-1.2	-1.0	-0.5	-1.1	-0.4	-0.6	-0.9
Age at First Birth	0.5	0.7	1.4	1.1	0.8	1.2	1.0	0.0	0.0	0.0	0.8	1.1	1.1
Pack years adult smoking proportion	0.5	0.8	1.4	-0.8	-0.8	-1.2	-0.6	-1.2	-0.5	-1.1	-0.4	-0.9	-0.9
Alcohol intake versus 10 years previously	0.5	0.8	1.5	-0.9	-1.1	-0.9	-0.4	-1.2	-0.9	-0.9	-0.4	-1.0	-0.9
Worrier / anxious feelings	0.5	1.0	2.7	-0.8	-0.7	0.0	-1.1	-0.7	-1.4	0.7	-1.6	-0.8	-1.0
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.1	0.7	0.2	1.3	1.0	0.7	-0.8	1.4	0.5	0.6	0.9
Tense / ‘highly strung’	0.5	0.9	3.9	-0.2	0.8	1.1	-0.3	0.4	-0.6	1.4	-2.0	-0.3	-0.5
Pulse wave reflection index	0.5	0.6	1.8	-0.5	-0.8	-1.0	0.1	-1.1	-0.6	-1.4	0.5	-0.7	-0.4
Medication: Paracetamol	0.5	0.8	2.1	-0.8	-0.6	-0.3	-0.9	-0.8	-1.3	-0.4	-1.4	-0.8	-1.0
Forced vital capacity (FVC), Best measure	0.5	1.7	3.2	1.2	1.8	1.1	1.4	1.5	1.8	0.8	0.8	1.1	1.3
Qualifications: College or University degree	0.5	1.6	2.9	-1.4	-0.6	-1.0	-1.1	-1.6	-1.7	-0.2	-1.2	-1.5	-1.5
Commuting to job workplace: Car/motor vehicle	0.5	0.6	0.9	0.9	0.7	0.8	0.7	0.8	0.8	0.6	0.6	0.9	0.8
Supplements: Vitamin C	0.5	0.6	2.9	-0.3	0.1	0.9	-0.1	0.4	-0.6	1.3	-1.7	-0.2	-0.3
Whole body fat-free mass	0.5	3.1	7.2	-1.2	-2.4	-2.7	-0.9	-2.2	-0.7	-2.5	1.3	-1.2	-0.9
Whole body water mass	0.5	2.9	6.8	-1.2	-2.3	-2.6	-0.8	-2.1	-0.7	-2.5	1.3	-1.2	-0.8
Irritability	0.5	0.8	2.7	0.6	1.2	1.2	0.4	0.8	0.7	1.6	-0.6	0.5	0.3
Neuroticism (Nagel 2018)	0.4	1.0	5.2	-0.9	-0.3	0.1	-0.9	-0.3	-0.7	0.6	-2.3	-0.9	-1.1
Impedance of leg (right)	0.4	1.9	11.7	-0.4	0.6	1.5	-0.9	1.0	-0.5	1.2	-3.4	-0.4	-0.8
High blood pressure (mother)	0.4	0.6	0.8	-0.8	-0.9	-0.6	-0.7	-0.8	-0.7	-0.7	-0.8	-0.7	-0.8
Impedance of leg (left)	0.4	2.0	12.9	-0.9	0.2	1.0	-1.2	0.5	-0.9	0.9	-3.6	-0.8	-1.2
Hearing difficulty/problems with background noise	0.4	0.6	1.7	0.8	0.1	0.4	1.0	0.5	0.7	0.4	1.3	0.7	1.0
Qualifications: None of the above	0.4	0.9	2.0	1.0	0.1	0.5	1.2	0.9	0.9	-0.1	1.4	0.9	1.2
Impedance of arm (right)	0.4	1.9	5.2	0.5	1.9	1.9	-0.4	1.4	0.5	1.9	-2.3	0.6	-0.1
Impedance of arm (left)	0.4	1.7	3.9	0.6	1.8	1.9	-0.2	1.4	0.5	2.0	-1.8	0.7	0.1
Length of working week for main job	0.4	0.4	1.8	-0.3	-0.9	-0.9	0.0	-0.6	0.1	-1.3	0.6	-0.4	-0.1
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	3.0	0.6	1.1	0.2	0.6	0.7	1.7	0.0	0.2	0.5	0.5
Health satisfaction	0.4	0.5	0.9	0.7	0.4	0.9	0.6	0.7	0.4	0.9	0.3	0.8	0.7
Mouth/teeth dental problems: Loose teeth	0.4	0.5	0.8	-0.7	-0.9	-0.9	0.0	-0.8	-0.3	-0.8	-0.1	-0.9	-0.5
Neck or shoulder pain in last month	0.4	0.6	2.3	-0.0	-0.8	-1.2	0.0	-1.1	-0.2	-0.8	1.5	-0.1	-0.0
Migraine (self-reported)	0.4	0.5	0.9	0.8	1.0	0.8	0.7	0.2	-0.1	0.7	0.8	0.8	0.7
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.2	0.8	0.8	0.6	0.3	0.7	1.1	0.2	0.4	0.9	0.6
Hypertension (Self-reported)	0.4	1.2	2.3	-1.0	-1.3	-1.2	-0.9	-1.5	-1.5	-0.8	0.1	-0.9	-0.9
Ever had bowel cancer screening	0.4	0.4	1.3	0.5	0.4	0.3	1.2	0.5	0.5	-0.1	1.0	0.4	0.8
Miserableness	0.4	0.7	1.4	0.6	0.8	1.0	1.2	1.0	0.5	1.0	0.5	0.6	0.9
Guilty feelings	0.4	0.7	1.1	0.7	1.1	0.7	1.0	0.8	0.9	0.5	1.0	0.5	0.9
Medication: Lisinopril	0.4	0.5	1.5	-0.7	-0.7	-0.4	-0.8	-0.7	-1.2	-0.3	-0.8	-0.7	-0.8
Cholesterol lowering medication	0.4	0.6	1.2	-0.6	-1.0	-1.1	-0.2	-1.1	-0.7	-1.0	0.6	-0.7	-0.4
Pack years of smoking	0.4	0.6	1.3	-0.6	-0.7	-1.1	-0.5	-1.1	-0.4	-1.0	-0.1	-0.7	-0.8
Reaction Time	0.3	0.7	1.8	0.7	0.1	0.8	0.9	-0.0	-0.8	1.1	1.3	0.7	0.8
Systolic Blood Pressure	0.3	1.6	4.7	1.4	0.8	0.8	1.1	0.8	1.0	1.0	2.2	1.4	1.4
Smoking Status	0.3	0.7	1.5	0.8	0.9	0.5	1.0	1.0	1.2	0.0	0.7	0.7	0.9
Neuroticism	0.3	0.7	3.8	-0.7	0.2	0.3	-0.6	-0.2	-0.7	0.5	-2.0	-0.8	-0.9
Relative age of first facial hair	0.3	0.7	2.1	-1.1	-0.4	-0.5	-0.3	-0.4	-0.0	-0.9	-1.4	-1.2	-0.9
Pain all over the body in last month	0.3	0.3	1.0	-0.7	-0.6	-0.3	-0.1	-0.2	-0.3	-0.6	-1.0	-0.8	-0.5
Neuroticism score	0.3	0.7	3.1	-0.8	-0.2	0.2	-0.6	-0.4	-1.1	0.6	-1.8	-0.8	-0.8
Trunk fat-free mass	0.3	1.9	4.4	-0.9	-2.1	-2.1	-0.5	-1.6	-0.5	-2.0	1.2	-0.9	-0.6
Number of live births	0.3	0.4	1.1	-0.4	-0.8	-1.0	-0.2	-0.9	-0.2	-1.1	0.7	-0.3	-0.3
Trunk predicted mass	0.3	1.8	4.2	-0.9	-2.0	-2.0	-0.5	-1.6	-0.5	-2.0	1.2	-0.9	-0.6
Medication for pain relief, constipation, heartburn	0.3	0.5	1.8	0.6	0.2	-0.1	0.4	0.4	1.3	-0.1	1.1	0.7	0.6
Medication: Ibuprofen	0.3	0.4	0.8	0.6	0.7	0.9	0.7	0.5	-0.0	0.8	0.4	0.6	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.3	0.5	0.4	0.7	-0.1	0.7	0.3	1.1	-0.1	0.6	0.3
Number of full sisters	0.3	0.3	1.9	0.0	-0.4	-0.5	0.2	-0.2	0.6	-1.4	0.6	-0.0	0.1
Medication: Aspirin	0.3	0.4	1.1	-0.6	-0.6	-0.1	-0.4	-0.4	-1.1	0.2	-0.8	-0.7	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.7	0.5	0.6	0.4	0.8	0.5	0.4	0.1	0.7	0.4	0.7
Average weekly beer plus cider intake	0.3	0.5	2.5	0.1	0.2	-0.5	-0.2	0.4	1.6	-1.4	-0.3	0.1	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.1	-0.4	-0.5	-1.0	-0.8	-0.8	-0.3	-1.0	0.3	-0.3	-0.5
Impedance of whole body	0.3	1.7	8.6	-0.1	1.3	1.6	-0.7	1.1	0.1	1.5	-2.9	-0.0	-0.5
Depressed Affect (Nagel 2018)	0.2	0.5	1.6	0.4	0.4	1.0	0.5	0.9	0.3	1.3	-0.6	0.3	0.4
Depression (Nagel 2018)	0.2	0.2	0.9	-0.2	0.1	0.5	-0.2	0.4	-0.5	0.9	-0.9	-0.2	-0.2
Heel T-Score	0.2	1.6	2.9	1.2	1.6	1.7	1.3	1.2	0.5	1.7	0.4	1.1	1.1
Height	0.2	3.7	5.8	-1.9	-2.0	-1.8	-2.4	-1.6	-1.2	-2.0	-2.2	-1.8	-2.1
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.1	-0.6	-1.0	-0.7	-0.4	-0.6	-0.4	-0.6	-0.2	-0.6	-0.5
Average weekly spirits intake	0.2	0.2	0.6	0.5	0.1	0.3	0.6	0.5	0.3	0.1	0.8	0.5	0.7
Vitamin and mineral supplements	0.2	0.2	0.9	-0.1	-0.3	-0.7	-0.1	-0.5	-0.1	-0.8	0.9	-0.1	0.0
Supplements: Zinc	0.2	0.2	0.6	-0.6	-0.6	-0.1	-0.3	-0.1	-0.6	0.2	-0.8	-0.6	-0.4
Medication: Co-codamol	0.2	0.2	0.9	-0.3	-0.4	-0.2	-0.1	-0.4	-0.8	-0.9	-0.1	-0.3	-0.2
Fed-up feelings	0.2	0.3	1.6	0.4	-0.0	0.8	0.3	0.8	0.1	1.3	-0.2	0.4	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.8	-0.6	-0.6	-0.3	-0.3	-0.4	-0.9	-0.0	-0.7	-0.7	-0.5
Tinnitus: Yes, but not now, but have in the past	0.2	0.3	0.9	-0.3	-0.9	-0.5	-0.6	-0.5	-0.7	-0.2	-0.0	-0.2	-0.3
Serious illness, injury or assault to yourself	0.2	0.2	0.8	0.3	0.5	-0.1	0.2	-0.3	0.4	0.6	0.9	0.3	0.2
Medication: Atenolol	0.2	0.3	1.3	-0.2	0.2	0.5	-0.4	0.3	-0.5	0.8	-1.1	-0.2	-0.3
Sitting height	0.2	1.3	3.0	1.2	1.3	1.0	0.9	1.2	1.7	0.7	0.8	1.2	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.4	1.9	-0.3	0.2	0.5	-0.3	0.1	-0.7	0.6	-1.4	-0.3	-0.5
Hair/balding pattern: Pattern 2	0.2	0.3	0.9	0.4	0.4	-0.0	0.6	0.3	0.8	0.2	1.0	0.4	0.6
Forced vital capacity (FVC)	0.2	0.9	2.0	0.7	1.4	0.9	1.0	1.1	1.1	0.8	0.4	0.6	0.9
Happiness	0.2	0.3	0.6	0.5	0.4	0.6	0.1	0.8	0.6	0.7	0.3	0.6	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.6	0.3	0.7	0.8	0.3	0.5	-0.0	0.6	-0.5	0.3	0.2
Peak expiratory flow (PEF)	0.2	0.4	1.7	0.2	-0.1	-0.4	0.7	0.0	0.4	-0.8	1.3	0.1	0.6
Glaucoma (self-reported)	0.2	0.3	0.8	-0.3	-0.6	-0.6	-0.5	-0.9	-0.6	-0.6	0.2	-0.3	-0.5
Birth weight	0.2	0.3	0.8	-0.5	-0.7	-0.9	-0.3	-0.8	-0.1	-0.7	0.3	-0.5	-0.5
Chronic bronchitis/emphysema (mother)	0.2	0.3	1.4	-0.4	-0.3	0.0	-0.3	0.3	0.3	-0.7	-1.2	-0.4	-0.4
Mean time to correctly identify matches	0.2	0.4	2.7	-0.2	-0.7	-0.1	-0.1	-0.8	-1.6	0.5	0.4	-0.2	-0.2
Heart disease (mother)	0.2	0.3	0.7	0.6	0.3	0.2	0.3	0.3	0.9	0.2	0.8	0.7	0.5
Overall health rating	0.2	0.3	1.7	0.2	-0.6	-0.4	0.0	-0.5	-0.7	-0.3	1.3	0.3	0.3
Chest pain or discomfort	0.2	0.3	0.8	0.6	0.4	0.2	0.6	0.4	0.7	0.0	0.9	0.6	0.6
Age at last live birth	0.2	0.3	0.7	-0.3	-0.8	-0.8	-0.6	-0.5	-0.0	-0.4	0.2	-0.3	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	0.7	0.6	0.8	0.6	0.5	0.7	0.8	0.3	0.3	0.6	0.5
Average weekly red wine intake	0.2	0.3	1.3	-0.6	-0.2	-0.1	-0.5	-0.2	-0.6	0.1	-1.2	-0.6	-0.6
Mood swings	0.2	0.3	0.9	-0.4	-0.4	0.1	-0.4	-0.4	-0.8	0.5	-0.9	-0.4	-0.5
Friendships satisfaction	0.2	0.2	1.5	-0.4	-0.1	-0.0	-0.3	0.3	0.4	-0.3	-1.2	-0.4	-0.4
Back pain experienced in last month	0.2	0.3	1.9	0.4	-0.7	-0.1	0.5	-0.2	-0.2	0.4	1.4	0.4	0.5
Mineral and other dietary supplements	0.2	0.2	1.3	0.4	-0.0	-0.1	0.3	0.2	0.3	0.0	1.1	0.5	0.6
Illnesses of father: None of the above (group 1)	0.2	0.2	0.4	-0.4	-0.6	-0.4	-0.5	-0.5	-0.6	-0.3	-0.3	-0.3	-0.4
Ever taken oral contraceptive pill	0.2	0.3	0.6	-0.2	-0.5	-0.7	-0.2	-0.8	-0.5	-0.6	0.7	-0.1	-0.2
Financial situation satisfaction	0.2	0.2	0.7	-0.5	-0.4	-0.3	-0.3	-0.0	0.3	-0.2	-0.9	-0.5	-0.4
High cholesterol (Self-reported)	0.2	0.3	1.8	-0.3	-0.8	0.0	0.0	-0.3	-1.3	0.1	0.2	-0.3	-0.0
Pain experienced in last month	0.2	0.3	1.8	-0.5	0.1	0.3	-0.2	0.2	-0.2	0.2	-1.3	-0.5	-0.4
Alzheimer’s Disease (in father)	0.1	0.1	0.3	-0.2	-0.0	-0.6	-0.6	-0.5	0.0	-0.4	0.2	-0.1	-0.3
Verbal and Numeric Reasoning (VNR)	0.1	0.3	0.7	-0.5	-0.4	-0.4	-0.5	-0.7	-0.8	-0.3	-0.5	-0.5	-0.6
Neuroticism (2016)	0.1	0.2	0.8	0.5	0.9	0.4	0.3	0.3	0.4	0.1	0.3	0.4	0.3
Blood Red Count	0.1	0.8	1.4	0.9	0.6	1.0	1.0	1.2	0.7	0.4	0.6	0.9	1.1
Hair Pigment	0.1	1.6	4.2	-1.1	-1.5	-1.9	-0.6	-1.4	-0.6	-2.0	0.5	-1.1	-0.8
Systolic blood pressure, automated reading	0.1	0.2	1.5	0.3	-0.1	-0.2	0.3	-0.1	-0.1	-0.1	1.2	0.3	0.4
Diabetes (mother)	0.1	0.2	0.5	0.3	-0.2	-0.1	0.3	0.1	0.5	-0.7	0.6	0.3	0.3
Supplements: Glucosamine	0.1	0.1	0.2	-0.2	-0.4	-0.4	-0.1	-0.4	-0.4	-0.3	0.1	-0.3	-0.2
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.5	-0.2	-0.2	-0.0	-0.1	-0.0	-0.7	-0.1	-0.2	-0.2	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.1	0.7	-0.2	-0.2	0.3	0.1	-0.1	-0.8	0.4	-0.4	-0.3	-0.1
Mouth/teeth dental problems	0.1	0.1	0.4	-0.0	0.3	0.2	-0.5	0.2	0.4	0.5	-0.6	0.2	-0.2
Medication: Simvastatin	0.1	0.1	0.5	0.0	-0.4	0.1	0.5	-0.1	-0.6	0.2	0.7	0.0	0.3
Falls in the last year	0.1	0.1	0.3	0.1	-0.2	-0.2	0.5	-0.1	0.3	-0.4	0.6	-0.0	0.2
Hair/balding pattern: Pattern 3	0.1	0.2	0.9	-0.3	0.3	0.3	-0.2	0.2	-0.4	0.2	-1.0	-0.3	-0.3
Noisy workplace	0.1	0.1	0.5	-0.2	0.0	-0.5	0.2	-0.7	-0.2	-0.5	0.3	-0.3	-0.2
Mouth/teeth dental problems: Dentures	0.1	0.2	0.6	0.2	-0.2	-0.3	0.3	-0.0	0.5	-0.6	0.8	0.2	0.3
Medication: Cholesterol lowering	0.1	0.2	0.7	0.2	-0.1	0.5	0.2	0.2	-0.8	0.7	0.4	0.3	0.4
Hair/balding pattern: Pattern 4	0.1	0.3	1.1	0.3	-0.5	-0.6	-0.2	-0.6	0.2	-0.5	1.0	0.3	0.1
Birth weight of first child	0.1	0.1	0.8	-0.1	0.1	0.1	-0.3	0.3	0.2	-0.1	-0.9	-0.1	-0.3
Ever highly irritable/argumentative for 2 days	0.1	0.2	0.6	0.4	0.2	0.4	-0.2	0.4	0.2	0.8	-0.0	0.5	0.2
High blood pressure (siblings)	0.1	0.2	0.4	-0.2	-0.6	-0.5	-0.4	-0.6	-0.4	-0.6	0.4	-0.1	-0.2
Wheeze or whistling in the chest in last year	0.1	0.2	0.5	0.2	-0.1	0.5	0.2	0.7	0.4	0.4	-0.7	0.1	0.1
Number of children fathered	0.1	0.1	0.4	-0.0	0.0	-0.5	0.1	-0.2	0.2	-0.5	0.7	-0.1	0.1
Age at first live birth	0.1	0.2	0.4	0.5	0.2	0.2	0.1	0.4	0.3	0.4	0.6	0.5	0.5
Emphysema/chronic bronchitis	0.1	0.1	0.5	0.0	-0.3	-0.3	-0.2	-0.3	0.0	-0.7	0.3	0.1	-0.1
Alcohol intake frequency.	0.1	0.2	1.1	-0.2	-0.3	0.3	0.0	-0.3	-1.0	0.5	-0.1	-0.2	-0.1
Comparative height size at age 10	0.1	0.4	1.2	0.7	0.4	0.2	0.2	0.5	1.1	0.1	0.9	0.8	0.6
Leg pain on walking	0.1	0.2	0.4	-0.4	-0.7	-0.4	-0.3	-0.3	-0.3	-0.1	-0.5	-0.4	-0.4
Illnesses of father: Heart disease	0.1	0.1	0.3	0.4	0.6	0.4	0.3	0.3	0.3	0.3	0.3	0.4	0.3
Commuting to job workplace: Walk	0.1	0.2	0.6	0.1	0.4	0.2	0.8	0.1	0.7	-0.3	0.2	-0.0	0.3
Medication for cholesterol	0.1	0.1	0.5	0.2	0.0	0.1	-0.1	0.5	0.7	-0.5	-0.1	0.3	0.2
Osteoarthritis (self-reported)	0.1	0.2	1.1	-0.1	-0.2	-0.4	-0.1	-0.4	-0.3	-1.1	0.2	-0.1	-0.1
Medication: Gliclazide	0.1	0.1	0.3	-0.0	-0.4	-0.0	-0.6	0.1	-0.1	0.3	-0.4	0.1	-0.2
Smoking status: Current	0.1	0.1	0.4	-0.0	-0.5	-0.3	0.1	0.1	0.6	-0.3	0.3	0.0	0.1
Eye problems/disorders: Glaucoma	0.1	0.1	0.3	0.4	0.2	0.1	0.2	-0.1	0.2	0.2	0.5	0.4	0.2
Risk taking	0.1	0.2	0.8	0.3	0.2	0.2	0.6	0.2	0.1	-0.2	0.9	0.2	0.5
Diastolic blood pressure, automated reading	0.1	0.3	1.2	0.5	-0.0	-0.2	0.0	0.1	0.7	0.1	1.1	0.6	0.4
Commuting to job workplace: Cycle	0.1	0.1	0.2	0.2	0.0	0.3	0.4	0.2	0.2	0.4	-0.0	0.1	0.2
Basal cell carcinoma (self-reported)	0.1	0.1	0.3	-0.1	-0.0	0.1	0.3	-0.2	-0.4	0.5	-0.1	-0.2	-0.1
Alcohol drinker status: Previous	0.1	0.1	0.2	0.3	0.0	0.3	0.1	0.0	-0.4	0.3	0.4	0.3	0.3
Intelligence (Savage-Jansen 2018)	0.0	0.1	0.4	0.2	0.6	-0.1	0.1	-0.3	-0.2	-0.1	0.2	0.2	-0.1
Schizophrenia vs Biploar Disorder	0.0	0.1	0.2	-0.1	-0.3	-0.1	-0.4	0.1	-0.0	0.2	-0.4	-0.0	-0.2
Ovarian Cancer	0.0	0.0	0.1	-0.0	0.0	-0.0	-0.1	-0.0	0.2	-0.2	-0.3	-0.0	-0.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood White Count	0.0	0.0	0.2	0.1	-0.1	-0.1	0.1	0.2	0.2	-0.1	0.5	0.0	0.3
Waist Hip Ratio (WHR)	0.0	0.1	0.3	0.0	0.1	-0.1	0.6	0.0	0.4	-0.5	0.2	-0.0	0.2
Tanning	0.0	0.2	1.0	-0.1	0.8	-0.1	-0.4	-0.2	-0.3	1.0	-0.5	-0.3	-0.4
Medication: Metformin	0.0	0.1	0.3	0.1	-0.3	-0.2	-0.0	-0.4	-0.4	-0.0	0.5	0.2	0.0
Current tobacco smoking	0.0	0.1	0.2	-0.1	-0.5	-0.3	-0.0	-0.0	0.3	-0.2	0.1	-0.1	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.0	0.3	-0.0	-0.0	0.2	0.2	0.0	-0.6	0.3	-0.0	-0.1	0.1
Forced expiratory volume in 1-second (FEV1)	0.0	0.1	0.5	-0.3	0.0	-0.4	0.1	-0.1	0.1	-0.7	-0.1	-0.5	-0.1
Medication: Lansoprazole	0.0	0.0	0.2	-0.0	-0.1	-0.1	-0.0	0.2	0.5	-0.0	-0.2	-0.0	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.2	0.9	-0.2	0.1	-0.5	0.1	0.1	0.6	-0.9	0.0	-0.3	-0.0
Standing height	0.0	0.2	0.6	-0.4	-0.4	-0.6	-0.8	-0.3	0.4	-0.4	-0.5	-0.3	-0.5
Osteoporosis (self-reported)	0.0	0.0	0.1	0.2	0.3	0.3	-0.1	0.0	0.0	-0.1	0.1	0.3	0.1
Hearing aid user	0.0	0.0	0.1	-0.2	-0.1	-0.3	0.0	-0.2	0.1	-0.3	0.1	-0.2	-0.1
Medication: Blood pressure	0.0	0.1	0.2	-0.3	-0.4	-0.3	0.0	-0.4	-0.2	0.3	0.1	-0.3	-0.2
Medication: Paracetamol	0.0	0.1	0.2	-0.0	0.2	0.1	-0.3	-0.2	-0.3	-0.3	-0.4	0.0	-0.3

Hub : Genes

MMEL1

Models

Trait associations