TWAS
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Models
Genes
Traits
[Hub]/) :
Traits
:
Hypothyroidism (self reported)
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chr2:159,476,732-161,166,234
Best TWAS P=1.64e-07 · Best GWAS P=1.78e-07 conditioned to 1
159.4M
159.6M
159.8M
160M
160.2M
160.4M
160.6M
160.8M
161M
161.2M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Artery Tibial
AC009506.1
0.11
0.11
lasso
4
0.10
5.5e-08
5.2
-5.2
1.6e-07
-1.00
0.02
0.98
TRUE
2
NTR
Blood
BAZ2B
0.05
0.05
lasso
6
0.05
5.1e-16
4.9
5.1
2.9e-07
0.76
0.06
0.94
FALSE