TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Hypothyroidism (self reported)
:
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chr3:104,683,753-106,283,820
Best TWAS P=7.97e-09 · Best GWAS P=1.76e-18 conditioned to 1.54e-18
104.6M
104.8M
105M
105.2M
105.4M
105.6M
105.8M
106M
106.2M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
CBLB
0.05
0.00
blup
104
0.02
0.0022
-5.6
-5.8
8.0e-09
0.00
0.01
0.90
TRUE
1
GTEx
Thyroid
CBLB
0.10
0.02
lasso
9
0.02
0.0083
-4.3
5.2
2.6e-07
-0.03
0.36
0.08
FALSE