TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Hypothyroidism (self reported)
:
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chr3:191,820,205-193,330,022
Best TWAS P=5.52e-08 · Best GWAS P=6.31e-08 conditioned to 1
191.8M
192M
192.2M
192.4M
192.6M
192.8M
193M
193.2M
193.4M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells EBV-transformed lymphocytes
MB21D2
0.73
0.56
lasso
3
0.63
6.9e-26
-5.4
-5.4
5.5e-08
0.99
0
1
TRUE