TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Hypothyroidism (self reported)
:
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→
chr4:122,961,964-124,352,460
Best TWAS P=1.74e-07 · Best GWAS P=3.88e-09 conditioned to 0.00657
123M
123.2M
123.4M
123.6M
123.8M
124M
124.2M
124.4M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
BBS12
0.1
0.02
lasso
6
0.02
0.0072
-5.8
-5.2
1.7e-07
0.87
0.01
0.84
TRUE