[Hub]/) : Traits : Hypothyroidism (self reported) : ← →

chr7:76,506,844-77,966,572

Best TWAS P=1.33e-07 · Best GWAS P=9.6e-08 conditioned to 0.19

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Artery Tibial	PTPN12	0.25	0.13	lasso	8	0.12	1.8e-09	5.2	-5.3	1.4e-07	-0.91	0.02	0.98	TRUE
5	The Cancer Genome Atlas	Thyroid Carcinoma	PTPN12	0.04	0.04	enet	4	0.04	1.0e-04	5.2	-5.3	1.3e-07	-0.99	0.01	0.98	FALSE
1	GTEx	Adrenal Gland	PTPN12	0.16	0.10	lasso	4	0.04	1.0e-02	5.3	-5.2	1.6e-07	-0.96	0.02	0.96	FALSE
4	The Cancer Genome Atlas	Breast Invasive Carcinoma	PHTF2	0.02	0.01	lasso	1	0.01	3.0e-03	5.2	-5.2	2.2e-07	-0.89	0.01	0.98	FALSE
3	GTEx	Colon Transverse	PTPN12	0.17	0.12	lasso	6	0.10	1.8e-05	5.3	-5.2	2.4e-07	-0.93	0.02	0.97	FALSE