[Hub]/) : Traits : Hypothyroidism (self reported) : ← →

chr7:127,878,155-129,284,182

Best TWAS P=8.11e-09 · Best GWAS P=5.89e-08 conditioned to 0.000772

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IRF5	0.11	0.05	blup	30	0.07	2.2e-08	4.5	5.8	8.1e-09	0.41	0.05	0.92	TRUE
3	The Cancer Genome Atlas	Lung Adenocarcinoma	IRF5	0.18	0.11	enet	9	0.14	1.6e-15	4.5	5.6	2.3e-08	0.36	0.05	0.92	FALSE
4	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	IRF5	0.14	0.15	enet	6	0.14	7.0e-10	-4.7	5.4	7.4e-08	0.37	0.03	0.95	FALSE
1	METSIM	Adipose	IRF5	0.05	0.04	lasso	7	0.04	2.2e-06	4.5	5.1	2.9e-07	0.42	0.11	0.87	FALSE