TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Hypothyroidism (self reported)
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chr8:23,139,436-23,678,000
Best TWAS P=3.66e-08 · Best GWAS P=9.22e-08 conditioned to 0.32
23.2M
23.3M
23.4M
23.5M
23.6M
23.7M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
SLC25A37
0.04
0.02
lasso
2
0.03
1.1e-04
-5.3
-5.5
3.7e-08
0.89
0
0.92
TRUE
1
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
SLC25A37
0.11
0.09
lasso
5
0.09
7.8e-10
-5.3
-5.5
3.9e-08
0.98
0
1.00
FALSE