TWAS
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About
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Models
Genes
Traits
[Hub]/) :
Traits
:
Hypothyroidism (self reported)
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chr8:128,107,136-129,812,343
Best TWAS P=1.48e-07 · Best GWAS P=9.13e-14 conditioned to 7.39e-14
128.2M
128.4M
128.6M
128.8M
129M
129.2M
129.4M
129.6M
129.8M
0
5
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Whole Blood
PVT1
0.12
0.07
lasso
4
0.06
6.3e-06
5.2
5.2
1.5e-07
0.01
0.97
0
TRUE
1
GTEx
Lung
PVT1
0.19
0.12
lasso
2
0.09
3.1e-07
5.2
5.1
3.0e-07
0.00
0.99
0
FALSE