TWAS
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Genes
Traits
[Hub]/) :
Traits
:
Hypothyroidism (self reported)
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chr8:140,969,818-142,706,843
Best TWAS P=2.31e-07 · Best GWAS P=1.91e-10 conditioned to 9.65e-06
141M
141.2M
141.4M
141.6M
141.8M
142M
142.2M
142.4M
142.6M
142.8M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
YFS
Blood
PTK2
0.02
0
blup
538
0.01
0.00086
3.8
-5.2
2.3e-07
-0.48
0.11
0.03
TRUE