TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Hypothyroidism (self reported)
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chr9:4,758,022-6,168,335
Best TWAS P=9.35e-08 · Best GWAS P=2.68e-11 conditioned to 3.27e-08
4.8M
5M
5.2M
5.4M
5.6M
5.8M
6M
6.2M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Pancreas
CD274
0.52
0.27
lasso
10
0.31
7.6e-14
5
-5.3
9.3e-08
-0.24
0.91
0.09
TRUE