Best TWAS P=1.68e-13 · Best GWAS P=2.62e-13 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Transverse | KIAA1683 | 0.15 | 0.02 | lasso | 3 | 0.02 | 3.3e-02 | 4.12 | -6.3 | 2.4e-10 | 0.88 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Nerve Tibial | KIAA1683 | 0.25 | 0.22 | lasso | 9 | 0.28 | 5.2e-20 | -7.31 | -5.5 | 2.8e-08 | 0.87 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Pituitary | KIAA1683 | 0.43 | 0.25 | lasso | 3 | 0.17 | 3.9e-05 | -6.68 | -6.8 | 1.5e-11 | 0.80 | 0.02 | 0.91 | FALSE |
| 4 | GTEx | Thyroid | KIAA1683 | 0.11 | 0.07 | enet | 14 | 0.12 | 2.1e-09 | -6.68 | -5.5 | 3.7e-08 | 0.75 | 0.02 | 0.98 | FALSE |
| 5 | GTEx | Vagina | LRRC25 | 0.63 | 0.02 | enet | 2 | 0.04 | 5.3e-02 | -7.31 | 7.3 | 3.2e-13 | -1.00 | 0.02 | 0.69 | FALSE |
| 6 | ROSMAP | Brain Pre-frontal Cortex | JUND | 0.17 | 0.17 | lasso | 5 | 0.20 | 2.7e-25 | -7.31 | -5.8 | 5.3e-09 | 0.92 | 0.00 | 1.00 | FALSE |
| 7 | YFS | Blood | KIAA1683 | 0.51 | 0.40 | enet | 65 | 0.46 | 9.9e-171 | -7.24 | -5.6 | 1.9e-08 | 0.91 | 0.00 | 1.00 | FALSE |
| 8 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | JUND | 0.05 | 0.04 | lasso | 1 | 0.04 | 4.3e-05 | -7.31 | -7.3 | 2.6e-13 | 1.00 | 0.00 | 0.99 | FALSE |
| 9 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | JUND | 0.11 | 0.03 | blup | 58 | 0.04 | 1.4e-03 | 0.62 | -5.8 | 7.8e-09 | 0.57 | 0.03 | 0.41 | FALSE |
| 10 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | KIAA1683 | 0.13 | 0.02 | blup | 65 | 0.05 | 1.0e-03 | -6.81 | -5.4 | 5.5e-08 | 0.79 | 0.00 | 0.98 | FALSE |
| 11 | The Cancer Genome Atlas | Brain Lower Grade Glioma | JUND | 0.04 | 0.03 | lasso | 2 | 0.02 | 7.9e-04 | -7.31 | -7.4 | 1.7e-13 | 1.00 | 0.00 | 0.99 | TRUE |