TWAS
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Traits
[Hub]/) :
Traits
:
Hypothyroidism (self reported)
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chr19:9,763,152-11,186,711
Best TWAS P=1.12e-07 · Best GWAS P=1.81e-11 conditioned to 1.42e-05
9.8M
10M
10.2M
10.4M
10.6M
10.8M
11M
11.2M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adrenal Gland
TYK2
0.27
0.06
lasso
5
0.12
6e-05
2.8
-5.3
1.1e-07
0.63
0.01
0.91
TRUE