[Hub]/) : Traits : Hypothyroidism (self reported) : ←

chr22:41,071,659-42,614,362

Best TWAS P=1.24e-07 · Best GWAS P=1.5e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Nerve Tibial ACO2 0.06 0.05 lasso 5 0.04 8.5e-04 -4.8 -5.2 1.6e-07 0.88 0.10 0.88 FALSE
2 GTEx Testis TEF 0.06 0.05 lasso 5 0.04 5.5e-03 -5.2 -5.1 2.9e-07 0.96 0.04 0.90 FALSE
3 NTR Blood TEF 0.01 0.02 lasso 2 0.02 3.8e-06 -5.2 -5.3 1.2e-07 0.97 0.02 0.97 TRUE
4 YFS Blood TEF 0.09 0.17 lasso 2 0.17 9.0e-53 -5.3 -5.3 1.3e-07 0.95 0.02 0.98 FALSE
5 The Cancer Genome Atlas Colon Adenocarcinoma TEF 0.04 0.03 blup 36 0.03 9.5e-03 -4.8 -5.3 1.4e-07 0.97 0.02 0.79 FALSE