Best TWAS P=4.4e-11 · Best GWAS P=3.55e-12 conditioned to 3.91e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TSPAN14 | 0.15 | 0.13 | enet | 17 | 0.15 | 3.2e-18 | -6.3 | 6.3 | 3.7e-10 | 0.04 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | TSPAN14 | 0.13 | 0.04 | lasso | 4 | 0.06 | 1.9e-05 | -6.3 | -5.9 | 3.2e-09 | -0.05 | 0.00 | 1.00 | FALSE |
| 3 | YFS | Blood | TSPAN14 | 0.31 | 0.34 | lasso | 7 | 0.38 | 8.3e-132 | -6.3 | -6.4 | 2.1e-10 | -0.05 | 0.00 | 1.00 | TRUE |
| 4 | YFS | Blood | ZMIZ1 | 0.02 | 0.02 | lasso | 2 | 0.02 | 4.8e-06 | -6.6 | -6.6 | 4.4e-11 | 0.61 | 0.02 | 0.98 | TRUE |