Hub : Genes

TSPAN14

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1520 0.0320 2.5e-14 0.133 0.147 0.153 0.153 0.143 7.1e-16 1.7e-17 3.2e-18 3.7e-18 4.5e-17
2 GTEx Brain Cerebellar Hemisphere 0.2910 0.1040 7.2e-04 0.079 NA 0.140 NA 0.083 4.6e-03 NA 2.0e-04 NA 3.8e-03
3 GTEx Brain Cerebellum 0.4020 0.0960 6.2e-06 0.083 NA 0.156 NA 0.121 1.9e-03 NA 2.3e-05 NA 2.0e-04
4 GTEx Lung 0.0710 0.0262 8.3e-04 0.019 NA 0.027 NA 0.034 1.2e-02 NA 3.7e-03 NA 1.2e-03
5 GTEx Skin Sun Exposed Lower leg 0.1280 0.0420 2.8e-04 0.037 NA 0.050 NA 0.056 4.6e-04 NA 5.1e-05 NA 1.9e-05
6 GTEx Thyroid 0.1060 0.0390 1.5e-04 0.052 NA 0.059 NA 0.066 7.8e-05 NA 2.4e-05 NA 8.4e-06
7 GTEx Whole Blood 0.0840 0.0270 8.6e-05 0.080 NA 0.068 NA 0.065 7.6e-08 NA 7.6e-07 NA 1.3e-06
8 METSIM Adipose 0.0626 0.0222 2.2e-05 0.007 0.022 0.014 0.020 0.008 2.4e-02 2.5e-04 2.7e-03 4.0e-04 1.9e-02
9 ROSMAP Brain Pre-frontal Cortex 0.0564 0.0273 3.2e-03 0.041 0.011 0.014 0.016 0.029 5.2e-06 1.4e-02 5.1e-03 2.9e-03 1.0e-04
10 YFS Blood 0.3145 0.0325 0.0e+00 0.338 0.335 0.368 0.367 0.377 2.5e-115 3.0e-114 3.1e-128 1.2e-127 8.3e-132
11 TCGA Kidney Renal Clear Cell Carcinoma 0.1089 0.0352 5.9e-10 0.054 0.093 0.082 NA 0.075 1.0e-06 1.2e-10 1.8e-09 NA 8.5e-09
12 TCGA Kidney Renal Papillary Cell Carcinoma 0.1140 0.0440 2.2e-04 0.053 0.062 0.060 NA 0.077 5.6e-04 1.8e-04 2.4e-04 NA 3.4e-05
13 TCGA Soft Tissue Sarcoma 0.1660 0.0750 1.1e-03 0.022 0.040 0.029 NA 0.028 1.6e-02 1.9e-03 7.2e-03 NA 8.2e-03
14 TCGA Thyroid Carcinoma 0.1180 0.0440 1.1e-08 0.118 0.101 0.122 NA 0.114 1.6e-11 4.4e-10 7.4e-12 NA 3.2e-11

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 0.4 0.7 2.9 1.7 -0.0 -0.3 -0.5 0.2 -0.1 -1.7 0.8 0.6 0.1 0.9 0.1 1.3 0.5
Bipolar Disorder or Schizophrenia 0.7 1.7 6.1 1.1 0.9 1.8 0.3 -0.9 0.7 0.2 0.7 0.5 -0.8 2.3 2.5 0.8 1.9
Depressed Affect (Nagel 2018) 0.1 0.2 0.9 -0.2 0.6 0.1 0.1 0.2 -0.1 1.0 0.8 -0.7 0.2 -0.1 -0.6 0.2 0.1
Depression (Nagel 2018) 0.5 0.7 1.7 0.1 0.2 -1.3 -1.0 0.4 -1.0 -0.4 -0.3 -1.0 0.7 -1.2 -1.2 0.3 -1.1
Intelligence (Savage-Jansen 2018) 1.7 5.2 15.5 -3.9 1.4 1.8 2.9 3.0 2.8 2.1 1.9 1.3 3.4 -1.6 0.3 -1.9 -0.2
Neuroticism (Nagel 2018) 0.1 0.2 1.0 0.2 0.5 0.5 -0.1 -0.7 -0.4 0.6 0.5 -1.0 -0.6 -0.0 0.0 0.2 0.3
Schizophrenia (2018) 1.2 2.4 9.6 0.1 1.2 2.5 0.7 -1.4 1.0 1.6 0.2 0.1 -1.1 2.3 3.1 0.0 2.0
Schizophrenia vs Biploar Disorder 0.7 0.9 2.8 -1.1 0.4 1.7 1.2 0.1 0.9 1.3 -0.1 0.4 0.2 0.1 1.2 -1.7 0.1
Worry (Nagel 2018) 0.2 0.4 1.6 0.9 0.3 0.7 -0.1 -1.1 -0.6 -0.1 -0.4 -1.3 -1.0 0.2 0.4 -0.1 0.4
Alzheimer’s Disease (in mother) 1.7 2.0 6.5 2.5 -1.3 -0.7 -1.3 -2.0 -1.4 -1.7 -1.3 -0.9 -2.1 1.2 0.2 0.5 -0.3
Alzheimer’s Disease (in father) 1.4 1.5 7.3 1.6 -1.2 -1.2 -0.8 -0.9 -1.1 -1.6 -0.6 0.5 -1.2 -0.3 -0.5 2.7 -1.2
Alzheimer’s Disease (including proxy) 3.3 4.8 14.0 3.7 -2.1 -1.4 -1.8 -3.0 -2.1 -2.5 -2.5 -0.3 -2.5 1.7 0.7 2.7 -0.6
Crohns Disease (2017) 5.9 13.0 40.1 6.2 -2.4 -1.0 -2.4 -6.0 -3.1 -2.1 -3.4 -1.4 -6.3 3.6 3.2 1.9 0.2
Irritable Bowel Disease (IBD) 5.3 12.6 40.4 6.3 -2.4 -1.2 -1.9 -5.9 -2.4 -3.0 -3.1 -1.8 -6.4 3.4 3.1 1.4 -0.0
Ulcerative Colitis (UC) 2.1 3.9 13.0 3.6 -1.4 -0.8 -1.0 -3.2 -1.1 -2.7 -1.2 -1.1 -3.4 1.6 1.3 0.3 -0.4
Major Depression (MDD) 1.3 1.6 4.9 0.7 -2.0 -2.2 -1.7 -0.3 -1.0 -1.2 -0.9 -1.3 -0.3 -1.0 -0.9 0.6 -1.6
Reaction Time 0.7 1.4 3.4 -0.6 0.2 1.4 1.3 0.8 1.0 1.7 1.6 0.4 1.2 1.1 0.4 -1.8 1.5
Verbal and Numeric Reasoning (VNR) 1.9 4.5 12.9 -3.6 1.3 1.0 2.7 2.9 2.4 2.2 1.9 1.5 3.1 -1.6 -0.2 -1.7 -0.3
Breast Cancer 0.2 0.5 1.6 0.8 -0.3 -0.1 0.8 -0.5 0.5 0.3 0.9 0.6 -0.4 1.0 0.7 -1.3 0.4
Ovarian Cancer 0.3 0.5 1.5 0.1 -0.1 -1.2 -0.8 0.0 -0.4 -0.4 -0.0 -0.4 -0.2 -1.1 -1.0 0.3 -1.2
Prostate Cancer 0.6 0.9 3.0 1.1 0.2 0.2 -0.8 -1.7 -0.9 0.1 -1.1 -0.6 -1.7 0.7 1.3 -0.4 0.2
Age at First Birth 1.8 2.6 8.2 1.3 0.1 -1.8 -1.9 -0.8 -1.1 -2.9 -2.2 -1.8 -0.9 0.8 0.3 2.4 -1.6
Bipolar Disorder (2011) 0.8 0.7 2.9 1.0 0.3 0.4 0.1 -0.3 0.6 -0.9 -0.0 0.7 -0.2 1.4 1.2 1.7 1.0
Body Mass Index (BMI) (2010) 0.5 0.7 2.0 -1.2 0.6 -0.2 0.3 1.0 0.2 0.6 1.3 -0.0 1.1 -1.1 -0.8 -1.4 0.2
Coronary Artery Disease (CAD) 3.4 4.0 14.8 -2.1 -1.4 -0.3 0.2 2.9 0.1 -0.1 0.6 0.2 3.0 -3.8 -3.3 -1.8 -1.7
Crohns Disease (2012) 3.8 6.2 18.3 3.9 -2.0 -0.6 -1.8 -4.1 -1.9 -1.7 -2.4 -1.6 -4.3 2.3 2.3 1.5 0.7
Mean Putamen Volume 0.1 0.1 0.4 -0.4 0.5 0.3 -0.4 -0.2 -0.1 0.4 -0.5 -0.2 0.1 -0.4 0.6 -0.3 -0.2
Fasting Glucose 0.6 0.7 3.5 -0.7 0.2 0.9 1.0 0.5 1.9 0.3 0.7 0.2 -0.0 1.0 0.9 0.3 1.1
HbA1C 0.6 0.6 4.5 -0.8 -0.5 0.2 -0.4 -0.1 0.4 2.1 0.4 1.0 0.2 0.7 0.7 -0.1 1.1
HDL Cholesterol 1.3 2.2 6.7 1.2 -0.5 -1.7 -2.4 -0.5 -2.6 -1.2 -1.5 -2.2 -0.3 -1.1 -1.4 -0.0 -1.5
LDL Cholesterol 3.5 5.5 14.4 2.8 -1.8 -1.4 -3.5 -2.5 -3.1 -1.7 -3.8 -1.7 -2.7 -0.9 -0.9 1.9 -1.8
Lupus 0.3 0.4 1.6 -0.5 0.2 0.1 -0.1 0.1 0.6 -0.2 -1.0 -0.9 -0.2 0.2 0.8 1.3 0.6
Neuroticism (2016) 0.2 0.3 1.7 0.4 -0.7 -0.2 -0.7 0.3 -0.4 -0.9 0.2 -0.6 0.1 -0.4 -0.6 1.3 0.2
Primary Biliary Cirrhosis 0.7 1.0 2.8 -1.2 -0.5 -0.9 -0.3 0.6 -0.3 1.0 1.3 0.0 1.3 -0.6 -1.7 -1.5 -0.8
Rheumatoid Arthritis 6.2 8.6 18.8 -4.3 2.5 2.3 4.3 4.0 3.9 2.0 2.8 1.8 3.9 -1.4 0.3 -2.8 0.6
Schizophrenia (2014) 1.0 2.1 9.6 0.6 1.8 1.9 0.2 -1.6 0.7 0.6 0.1 0.1 -1.4 2.2 3.1 0.3 1.4
Triglycerides 0.3 0.4 1.3 0.4 0.2 0.4 0.1 -0.7 0.4 0.1 -1.1 1.1 -1.0 -0.0 0.6 1.2 0.1
Type 2 Diabetes (T2D) (2012) 1.6 1.9 7.6 0.7 1.0 0.8 0.3 -2.7 0.1 1.4 -0.1 0.9 -1.7 1.7 2.3 -0.8 1.4
Ulcerative Colitis 1.4 2.0 5.9 2.4 -1.4 -1.0 -0.6 -2.4 -0.5 -2.2 -0.9 -1.0 -2.3 0.7 0.7 0.3 -0.1
Blood Eosinophil Count 0.2 1.5 5.2 1.5 -0.6 -1.0 -1.4 -2.3 -1.4 -0.6 -1.3 -0.7 -2.1 1.3 0.5 0.1 0.0
Blood Platelet Count 0.8 9.0 19.1 -1.9 3.1 3.2 4.2 -0.3 3.7 4.0 2.6 1.1 0.1 3.1 3.8 -2.0 4.4
Blood Red Count 0.5 4.5 18.3 -2.0 -2.1 -2.5 -1.6 1.5 -0.2 -0.4 -1.5 -0.1 1.9 -4.3 -3.2 0.2 -3.1
Blood White Count 1.7 12.9 26.4 5.0 -2.4 -3.5 -4.6 -5.1 -4.3 -1.5 -3.5 -3.1 -5.1 2.0 -0.5 3.4 -2.3
Heel T-Score 2.6 21.0 38.9 5.2 -3.4 -4.7 -6.2 -4.5 -4.5 -5.4 -5.6 -3.3 -5.0 -0.5 -1.4 5.6 -4.9
BMI 0.3 1.7 7.2 -0.6 -1.9 -1.0 -1.4 0.9 -1.4 0.2 0.0 -0.4 0.9 -2.2 -2.7 -0.2 -1.3
Height 0.3 6.3 12.5 -1.6 2.0 2.8 3.5 1.3 3.2 1.9 3.4 2.1 0.9 2.8 2.7 -1.2 3.5
Waist Hip Ratio (WHR) 0.7 3.1 7.7 -2.4 0.3 0.9 1.9 2.8 1.8 0.6 2.6 -0.2 2.6 -1.3 -1.3 -2.1 0.5
Systolic Blood Pressure 2.7 13.6 29.4 -4.6 2.5 5.1 4.5 4.0 2.9 5.4 4.0 2.9 4.3 -1.7 0.0 -3.1 3.1
Smoking Status 0.1 0.3 1.1 -0.2 -0.8 -0.2 -0.5 -0.4 -0.5 -0.1 -0.5 -1.0 -0.6 -0.4 -0.0 0.2 -0.5
Allergy or Eczema 0.3 0.8 1.6 -0.8 -0.6 1.1 1.1 1.3 -0.2 0.5 1.0 1.0 1.0 -0.1 -0.7 -1.2 0.8
Cardiovascular Disease 1.3 4.4 11.4 -2.5 0.5 1.4 1.3 3.0 -0.0 2.1 1.8 -0.0 3.4 -2.9 -3.0 -2.4 -0.2
Hypothyroidism (self reported) 0.0 0.1 0.3 -0.3 0.4 0.2 0.2 0.2 0.3 -0.0 -0.3 -0.2 0.2 0.2 0.5 0.5 0.5
Respiratory disease 3.0 6.8 22.5 -4.7 1.7 0.9 2.6 3.6 1.9 2.2 2.2 1.7 3.9 -2.2 -1.2 -3.4 0.0
Type 2 Diabetes (T2D) (2018) 0.5 0.9 3.4 0.1 0.8 1.5 0.2 -0.8 0.7 1.3 -0.8 0.6 -0.5 1.9 1.4 0.2 0.6
Lung FEV1/FVC ratio 9.9 50.2 94.3 9.7 -3.9 -8.2 -9.0 -7.5 -7.6 -8.8 -7.8 -4.9 -8.1 -0.0 -2.7 7.2 -6.5
Lung FVC 0.1 0.6 2.0 -1.0 1.4 0.2 1.1 0.8 0.4 0.5 0.8 0.6 0.8 -0.6 0.4 -1.2 0.3
Neuroticism 0.3 0.6 1.7 -1.2 0.7 0.9 0.8 0.6 0.8 1.3 0.9 -0.6 0.6 -0.1 0.0 0.3 1.1
Chronotype (morning person) 0.8 1.8 4.2 -2.0 0.3 1.5 2.0 0.6 1.9 1.5 0.2 1.4 0.9 0.4 1.1 -1.2 1.5
Hair Pigment 0.1 3.3 7.0 2.6 -0.6 -1.2 -1.7 -2.6 -1.4 -1.4 -2.4 -1.4 -2.6 1.4 0.8 2.6 -0.2
Tanning 0.7 8.1 20.9 -3.5 1.9 3.2 3.3 2.1 2.2 3.0 4.2 2.4 2.7 -0.9 0.9 -4.6 2.2
Hand grip strength (left) 0.4 1.1 6.2 -0.9 1.0 0.6 1.4 0.8 1.1 1.0 0.7 0.4 1.0 -0.7 0.4 -2.5 -0.0
Number of treatments/medications taken 1.4 2.5 7.1 -0.8 1.5 2.4 2.1 0.5 0.9 2.7 1.0 0.8 0.6 0.4 0.7 -2.1 2.5
Average weekly spirits intake 0.7 0.9 2.2 -1.5 -0.2 -1.1 -0.4 1.0 -0.7 -0.5 0.8 -1.0 0.9 -1.4 -1.5 -0.6 -0.8
Sensitivity / hurt feelings 0.5 0.8 2.1 0.3 0.8 1.4 0.6 -0.8 0.6 0.6 -0.0 0.5 -1.0 1.2 1.0 1.0 1.5
Frequency of depressed mood in last 2 weeks 0.2 0.3 0.7 -0.1 0.4 0.7 0.2 0.5 -0.1 0.7 0.7 -0.5 0.7 -0.7 -0.3 -0.8 0.9
Hearing difficulty/problems: Yes 1.3 1.9 6.1 -1.9 0.4 0.7 1.7 2.5 1.0 -0.2 0.9 -0.4 2.4 -1.3 -1.0 -1.7 0.8
Relative age of first facial hair 0.6 1.2 4.1 -1.4 1.7 0.9 2.0 1.0 1.5 0.6 1.1 0.5 0.8 -0.0 0.9 -0.2 0.7
Other serious medical condition/disability diagnosed by doctor 0.4 0.5 1.3 -0.8 -0.7 0.4 0.6 0.6 0.7 -0.1 -1.1 -0.2 0.7 -1.1 -0.6 -1.1 -0.0
Ever used hormone-replacement therapy (HRT) 1.9 2.4 6.7 -1.7 1.1 1.8 1.1 1.1 1.5 2.1 1.8 0.6 1.3 -0.1 0.6 -2.6 2.2
Ever had hysterectomy (womb removed) 1.0 1.2 4.3 1.0 1.4 1.8 0.1 -0.7 -0.2 1.4 0.4 2.1 -0.5 0.9 0.6 -0.1 1.2
Systolic blood pressure, automated reading 1.3 3.7 7.6 -1.8 0.7 2.8 2.4 2.4 1.3 2.2 2.5 0.4 2.4 -0.8 -0.3 -2.4 2.1
Eye problems/disorders: Diabetes related eye disease 1.5 1.7 7.2 -0.8 0.5 2.7 1.3 -0.1 1.3 1.7 0.5 1.6 -0.1 1.4 1.2 -0.5 1.6
Angina 2.0 2.6 7.6 0.4 -2.8 -1.4 -1.9 -0.3 -1.6 -1.4 -1.3 -1.1 -0.5 -2.5 -2.0 -0.3 -2.2
Medication for hormone replacement therapy 0.2 0.2 0.7 -0.8 0.1 -0.1 -0.3 0.2 0.8 -0.3 -0.4 0.0 0.1 0.2 0.4 0.8 -0.4
Vitamin and mineral supplements 1.5 2.0 8.0 -1.7 -0.7 -1.2 -1.1 0.5 -0.5 -1.0 -1.7 1.2 1.2 -2.8 -1.4 -0.4 -2.2
Supplements: Zinc 1.5 1.6 3.7 1.6 0.7 1.4 0.4 -1.6 -1.0 0.9 1.5 -0.1 -1.9 1.8 1.3 -0.8 1.1
Medication: Co-codamol 1.4 1.6 4.9 -1.4 1.0 1.1 1.9 0.2 1.4 2.0 0.8 2.2 0.8 0.0 1.1 0.1 1.2
Medication: Metformin 2.0 2.9 8.8 -0.3 1.4 2.1 1.6 -0.8 2.0 1.5 -0.2 2.0 -0.7 2.9 3.0 0.5 1.4
Diabetes (father) 1.0 1.2 3.8 0.2 0.3 1.7 0.8 -0.4 0.2 1.9 1.2 0.8 -0.2 1.2 0.8 -1.4 1.9
Diabetes (mother) 2.2 2.8 8.9 0.9 -1.2 -1.9 -1.6 0.9 -1.7 -2.1 -1.1 -1.2 0.8 -1.9 -3.0 0.9 -2.5
Severe depression (siblings) 0.7 0.8 2.9 -0.4 -0.0 -1.4 -1.4 0.1 -0.8 -0.0 -0.1 -0.4 0.4 -1.3 -0.9 0.8 -1.7
Pack years adult smoking proportion 1.1 1.7 5.2 -2.3 -0.7 -0.6 0.8 1.9 1.1 -0.0 -0.1 -1.1 2.3 -1.5 -0.9 -1.6 -0.3
Impedance of leg (right) 0.5 2.6 9.2 -1.2 1.1 3.0 1.9 1.2 1.7 0.9 1.5 0.5 1.5 1.0 1.7 -1.0 2.4
Leg fat-free mass (left) 0.1 0.3 0.8 -0.7 0.3 0.2 0.9 0.6 0.7 0.6 0.8 0.8 0.4 -0.3 -0.0 -0.2 0.3
Trunk fat percentage 0.3 1.2 3.5 -1.5 -0.0 1.9 0.9 1.3 0.8 1.3 1.3 0.7 1.2 -0.8 -0.3 -1.0 1.2
Hand grip strength (right) 1.1 2.9 7.0 -1.9 1.7 1.6 2.2 1.7 1.7 2.0 2.0 0.8 2.0 -0.7 0.5 -2.6 0.7
Townsend deprivation index at recruitment 0.1 0.2 0.8 0.3 -0.5 0.9 -0.0 0.2 -0.0 0.5 -0.0 0.1 0.3 -0.5 -0.7 -0.1 0.2
Current tobacco smoking 0.4 0.7 3.5 -1.1 -0.2 -1.1 -0.4 -0.0 0.4 -0.4 -0.9 0.1 -0.0 -1.4 -0.3 0.2 -1.9
Average weekly fortified wine intake 0.4 0.4 4.9 -0.1 -0.3 0.2 0.2 0.1 0.2 0.7 0.3 2.2 0.1 0.2 0.3 -0.3 -0.4
Maternal smoking around birth 4.7 6.8 22.0 -4.7 1.9 1.0 2.5 3.5 2.9 1.9 3.2 2.0 3.6 -2.6 -0.6 -1.8 0.3
Fed-up feelings 0.1 0.2 0.6 0.1 -0.2 -0.5 -0.2 -0.7 0.0 0.8 0.1 -0.2 -0.6 -0.1 -0.3 0.5 -0.0
Frequency of unenthusiasm / disinterest in last 2 weeks 0.4 0.6 2.2 0.7 0.3 -0.6 -1.0 -0.4 -0.7 -0.9 -1.5 -0.3 -0.4 -0.9 -0.2 1.1 -0.7
Relative age voice broke 0.5 0.8 1.8 -1.3 0.5 0.5 1.4 1.0 1.3 0.1 1.3 0.9 0.9 -0.4 0.3 -0.9 0.6
Taking other prescription medications 0.4 0.7 2.3 -0.3 0.3 1.5 1.0 0.3 0.4 1.2 0.4 0.5 0.3 -0.1 -0.3 -1.4 1.4
Age when periods started (menarche) 2.3 5.6 10.8 3.2 -2.7 -2.0 -3.3 -2.5 -3.3 -2.4 -2.4 -2.2 -2.7 0.3 -0.5 1.5 -1.7
Bilateral oophorectomy (both ovaries removed) 0.6 0.7 2.6 -0.1 -0.2 -0.6 -1.3 0.1 -1.2 -0.6 -0.6 -0.5 0.1 -1.6 -1.3 -0.0 -1.3
Heel bone mineral density (BMD) T-score, automated (left) 4.8 10.8 21.4 3.4 -3.8 -3.8 -4.5 -2.0 -3.5 -4.2 -2.8 -1.8 -2.4 -1.5 -2.1 3.4 -4.6
Tinnitus: Yes, but not now, but have in the past 1.6 1.8 5.7 -0.9 0.5 -0.4 0.4 2.1 -0.7 0.1 1.1 -0.8 1.9 -1.7 -2.4 -1.8 -0.8
Qualifications: CSEs or equivalent 0.8 1.1 4.4 -0.4 -2.1 -1.6 -1.0 0.2 -0.6 -0.5 -0.6 -1.1 0.2 -1.5 -1.4 0.2 -0.9
Serious illness, injury or assault to yourself 0.4 0.4 2.9 -0.9 0.3 0.7 0.4 -0.1 0.4 0.3 0.0 0.5 0.2 -0.1 0.4 -1.7 1.0
High blood pressure 1.6 4.6 12.5 -2.4 0.6 0.9 0.8 3.4 -0.3 1.4 1.7 -0.1 3.4 -3.5 -3.4 -1.8 -0.9
Hayfever, allergic rhinitis or eczema 0.5 1.1 3.3 -0.9 -0.8 0.4 1.1 1.8 -0.1 0.5 1.3 1.3 1.6 -0.4 -1.3 -1.4 0.3
Multivitamins +/- minerals 1.5 1.9 7.3 1.1 0.7 1.5 1.0 -0.6 0.8 0.2 1.6 -0.4 -1.4 2.7 2.2 0.4 1.8
Stomach or abdominal pain in last month 0.2 0.2 1.1 -0.3 0.1 -0.3 -0.0 0.6 -0.3 -0.3 0.4 -1.1 0.6 -0.4 -0.3 0.1 0.5
Supplements: Glucosamine 0.6 0.7 4.8 0.6 0.5 1.1 0.5 0.0 -0.3 0.3 0.6 0.1 0.0 1.4 0.7 0.8 2.2
Diverticular disease/diverticulitis (self-reported) 0.3 0.4 1.6 -0.7 -1.0 -0.3 -0.6 -0.0 -0.3 -0.1 -0.1 0.6 0.1 -0.9 -0.4 -0.2 -1.3
Medication: Atenolol 0.6 0.8 2.5 -0.9 0.2 0.0 -0.7 1.1 -0.5 0.5 1.5 -0.6 1.2 -1.1 -1.6 0.2 0.4
Medication: Levothyroxine sodium 0.1 0.1 0.5 -0.7 0.3 0.1 0.2 0.3 0.5 -0.2 -0.7 0.3 0.3 -0.2 0.4 0.1 -0.3
Sitting height 0.2 1.7 10.4 1.0 -1.9 -1.4 -0.6 0.4 -0.5 -3.2 -0.7 -1.1 -0.4 -0.8 -0.4 0.8 -1.8
Chronic bronchitis/emphysema (father) 0.5 0.6 2.4 -0.5 0.2 1.6 0.7 0.4 0.6 1.0 1.0 0.5 0.5 0.7 0.9 -0.6 0.5
High blood pressure (mother) 0.4 0.6 1.1 -1.0 0.9 0.9 1.0 0.5 0.6 0.9 0.7 -0.7 0.7 -0.5 -0.1 -0.7 1.1
Body mass index (BMI) 0.2 1.0 3.3 0.0 -1.7 -1.1 -1.0 0.2 -1.1 -0.6 -0.6 -0.7 0.0 -1.7 -1.8 0.3 -0.6
Impedance of leg (left) 0.4 2.0 6.2 -1.1 0.8 2.5 1.5 1.0 1.4 1.3 1.3 0.1 1.2 1.0 1.6 -1.1 2.2
Leg predicted mass (left) 0.1 0.3 0.8 -0.8 0.3 0.2 0.9 0.6 0.7 0.5 0.8 0.7 0.4 -0.4 -0.0 -0.2 0.2
Trunk fat mass 0.2 0.9 1.9 -1.4 -0.2 1.4 0.9 1.3 0.7 0.9 1.0 0.6 1.1 -0.9 -0.5 -0.9 1.0
Waist circumference 0.3 1.1 2.8 -1.4 -0.7 0.5 1.0 1.7 0.5 0.5 1.0 0.2 1.5 -1.2 -1.5 -1.1 0.3
Number of incorrect matches in round 4.3 7.2 25.2 5.0 -1.1 -1.7 -4.1 -3.2 -4.2 -1.5 -1.8 -1.7 -2.9 1.6 -1.1 2.1 -1.3
Past tobacco smoking 0.3 0.5 1.6 0.9 -0.1 -0.5 -0.9 -0.6 -0.6 -0.1 -0.6 -0.3 -0.3 -1.3 -0.7 -0.6 -1.3
Alcohol usually taken with meals 0.4 0.7 2.4 0.7 -0.5 -0.9 -1.4 -0.3 -0.5 -0.9 -1.2 -1.6 -0.8 -0.1 0.3 0.6 -0.2
Nervous feelings 1.1 2.0 4.9 2.1 0.1 -0.7 -1.4 -2.2 -1.3 -0.9 -1.2 -1.1 -2.1 1.7 0.5 1.9 0.5
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.4 2.4 0.3 0.8 0.1 -0.7 0.0 -0.4 -1.0 -1.5 -0.5 -0.0 -0.9 -0.3 0.0 0.2
Hearing difficulty/problems with background noise 1.1 1.8 5.0 -0.4 -0.3 0.7 1.0 2.2 0.4 -1.0 0.6 -1.6 2.1 -0.8 -2.1 -2.0 -0.9
Hair/balding pattern: Pattern 2 0.5 0.7 1.8 -0.5 1.0 0.1 1.0 1.3 1.2 -1.3 0.6 -0.6 0.8 -0.1 -0.2 -0.1 1.0
Had menopause 0.4 0.5 1.4 -0.2 0.9 0.6 0.7 0.5 0.2 1.0 1.0 0.2 0.7 0.4 0.2 -1.0 1.2
Had other major operations 0.2 0.3 2.3 -0.0 -0.2 -0.4 0.2 0.2 0.2 -0.1 -0.7 0.2 0.0 0.0 0.1 1.5 0.7
Forced vital capacity (FVC) 0.9 3.3 7.4 -1.7 1.8 1.9 2.7 0.7 2.2 1.8 2.1 1.5 0.7 0.9 2.3 -2.0 2.1
Heel bone mineral density (BMD) T-score, automated (right) 4.1 9.3 19.1 3.0 -4.1 -2.9 -4.4 -2.0 -3.1 -4.1 -2.8 -1.9 -2.2 -1.1 -1.5 3.2 -4.1
Ever unenthusiastic/disinterested for a whole week 0.8 1.0 2.1 1.0 -1.2 -1.3 -1.4 0.2 -1.3 -0.8 -0.4 1.0 -0.1 -0.3 -1.3 1.0 -1.4
Qualifications: None of the above 0.2 0.4 1.7 -0.5 0.9 0.5 1.3 0.3 0.5 0.5 0.6 0.2 0.2 0.5 0.4 -1.3 -0.2
Financial difficulties in last 2 years 0.6 0.8 2.6 -1.3 -0.4 0.6 1.0 1.0 1.0 0.7 0.8 1.6 0.9 0.1 -0.1 -0.3 1.1
Mouth/teeth dental problems 0.2 0.4 2.1 0.5 -0.1 -0.8 -0.8 -0.1 -0.0 -0.7 -0.9 -0.1 -0.1 0.2 -0.1 1.4 -0.5
Heart attack 2.5 3.2 11.3 0.7 -1.4 -2.2 -1.4 0.4 -1.4 -2.7 -2.2 -3.4 0.1 -1.8 -1.6 -0.5 -1.7
Allergy 0.8 1.8 4.5 1.8 0.7 -0.2 -0.4 -2.0 0.4 -0.8 -1.4 -1.1 -1.8 1.6 2.1 1.9 0.6
Pain all over the body in last month 0.6 0.7 2.7 0.0 0.1 1.3 0.5 -0.3 0.6 1.6 0.3 1.5 -0.1 1.1 0.6 -0.3 0.4
Diabetes (self-reported) 0.9 1.5 4.2 -0.6 1.5 2.1 0.7 -0.8 1.6 1.4 -0.6 0.8 -0.5 1.9 1.6 -0.2 0.7
Hayfever/allergic rhinitis (self-reported) 0.7 0.9 2.6 -0.6 0.4 0.9 1.6 0.7 0.8 1.4 1.0 1.3 0.6 -0.1 0.5 -1.5 0.9
Medication: Ramipril 1.0 1.3 4.4 -1.0 -0.5 0.6 -0.5 1.5 -1.3 0.6 -0.6 -0.3 1.6 -2.1 -1.8 -1.2 0.1
Medication: Simvastatin 1.0 1.5 4.9 -0.2 0.2 -0.1 -0.4 1.0 -1.1 -0.5 0.5 -1.1 1.3 -2.0 -2.2 -2.2 -0.9
Fluid intelligence score 0.9 1.9 5.2 -2.3 0.9 1.2 1.9 1.4 1.5 1.9 1.4 1.1 1.6 -0.5 0.3 -1.4 0.2
Illnesses of siblings 1.7 2.3 5.8 1.8 -1.0 -0.7 -1.3 -1.9 -0.9 -1.0 -2.3 0.2 -2.4 1.3 1.3 2.4 -0.8
Neuroticism score 0.1 0.2 1.0 -0.2 0.5 0.1 0.2 -0.3 0.2 0.5 -0.3 -1.0 -0.3 0.3 0.2 0.8 0.7
Weight 0.1 0.4 1.0 -0.8 -0.8 0.5 0.7 1.0 0.3 0.5 0.6 0.2 0.7 -0.9 -0.5 -0.5 0.7
Impedance of arm (right) 1.1 5.3 16.6 -1.7 2.3 4.1 2.6 1.2 2.3 2.5 2.7 2.3 1.5 1.3 2.1 -1.6 2.3
Arm fat percentage (right) 0.1 0.5 1.5 -0.9 -0.5 0.7 0.1 0.9 -0.2 0.5 0.8 0.2 0.8 -1.2 -1.2 -0.9 0.3
Trunk fat-free mass 0.0 0.2 0.8 -0.5 -0.4 -0.6 0.9 0.6 0.6 -0.1 0.3 -0.2 0.3 -0.2 -0.1 -0.6 0.4
Hip circumference 0.1 0.3 0.8 -0.9 0.0 0.4 0.6 0.6 0.1 0.8 0.4 0.7 0.5 -0.8 -0.4 -0.3 0.7
Time employed in main current job 1.2 1.4 3.1 1.8 -1.4 -1.2 -1.4 -1.4 -1.3 -1.4 -0.8 -0.8 -1.4 0.2 -0.9 -0.0 -1.1
Alcohol intake versus 10 years previously 0.8 1.3 3.8 0.6 0.3 1.9 0.3 -0.8 -0.6 1.0 1.3 1.6 -0.7 1.3 0.5 -1.1 1.9
Father’s age at death 1.0 1.4 5.4 1.9 -0.5 -0.3 -0.7 -2.3 -1.1 -0.1 -0.6 0.2 -2.3 1.1 1.0 0.4 -0.3
Worrier / anxious feelings 0.2 0.4 1.3 0.1 1.1 0.6 1.0 -0.2 0.6 0.2 0.4 0.5 -0.5 0.4 1.0 0.2 0.7
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.6 1.6 -0.8 0.2 0.6 0.8 1.0 0.5 1.0 -0.1 1.3 1.2 -0.2 -0.6 -0.5 0.5
Falls in the last year 0.7 1.0 4.8 -1.4 -1.1 0.2 0.7 0.7 0.0 0.4 0.8 0.6 1.0 -1.4 -0.7 -2.2 -0.1
Hair/balding pattern: Pattern 3 0.1 0.2 0.8 -0.7 -0.7 -0.0 0.3 0.7 0.5 -0.3 -0.2 -0.4 0.9 0.3 -0.2 -0.1 -0.3
Number of live births 0.5 0.7 2.8 -1.2 0.4 0.6 -0.3 0.5 -0.6 1.7 -0.5 -0.3 1.2 -0.4 -0.5 -1.5 0.3
Forced expiratory volume in 1-second (FEV1) 0.2 0.8 2.8 1.0 0.4 -0.1 -0.1 -1.6 -0.1 -0.7 -0.7 0.2 -1.6 1.0 1.7 0.3 0.2
Pulse rate 0.5 0.9 2.6 1.0 -0.6 -1.6 -1.2 -0.8 -0.9 0.1 -0.7 -1.3 -0.8 0.3 -0.5 1.2 -0.7
Happiness 0.6 0.8 2.6 0.5 -1.5 -0.7 -0.7 0.4 -0.8 -0.7 0.2 0.0 0.5 -0.9 -1.6 0.5 -1.5
Noisy workplace 1.7 2.1 7.6 1.0 -0.9 -2.1 -1.4 -0.4 -1.4 -2.1 -1.2 -1.7 -0.6 -0.6 -1.0 2.8 -0.9
Qualifications: A levels/AS levels or equivalent 0.4 1.0 4.6 -0.8 1.5 1.3 0.9 0.2 1.0 0.7 -0.3 1.3 -0.0 0.2 2.1 0.6 0.1
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.5 1.9 -0.2 -0.2 1.1 0.0 -0.1 0.1 -0.1 -0.8 1.4 0.0 -1.4 0.2 -0.8 -1.1
Mouth/teeth dental problems: Dentures 0.3 0.5 1.2 0.9 -0.4 0.4 -0.4 -0.4 -1.0 -0.6 -1.1 -0.0 -0.7 1.1 0.0 0.6 0.9
Asthma 2.5 5.0 15.3 -3.9 1.3 0.8 1.7 3.2 1.2 2.0 2.0 1.9 3.4 -2.3 -2.0 -2.3 -0.2
Medication: Ibuprofen (e.g. Nurofen) 1.8 2.3 5.0 -2.0 1.2 0.6 2.1 2.1 1.6 2.0 2.2 0.3 1.7 -0.4 0.5 0.5 1.3
Medication: Cholesterol lowering 0.4 0.6 3.0 -0.4 -0.5 0.0 -0.3 1.0 -0.2 0.0 -0.1 -1.3 1.1 -0.6 -1.7 -0.5 -0.0
Depression (self-reported) 0.2 0.3 1.1 -0.3 -0.6 -1.1 -0.2 0.2 0.1 0.2 -0.3 0.4 0.3 -0.5 -0.6 0.7 -1.1
Medication: Lansoprazole 0.3 0.3 1.6 0.9 -0.5 -0.0 -0.4 -0.4 -0.2 -0.7 -1.3 -0.6 -0.2 -0.7 -0.5 0.1 -0.3
Prospective memory result 4.7 5.8 14.6 3.8 -1.3 -2.4 -3.3 -2.5 -2.8 -2.6 -2.9 -2.0 -2.8 0.7 -0.5 2.4 -0.5
Lung cancer (father) 1.7 2.0 6.3 -0.2 1.6 1.0 1.6 -0.7 1.7 0.7 0.4 1.5 -0.8 2.5 2.4 -0.5 1.5
Illnesses of mother 1.4 1.7 8.6 -0.1 0.4 1.0 0.9 -1.2 1.5 1.0 -0.5 1.6 -1.1 1.8 2.9 0.8 1.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 0.8 2.3 1.2 0.2 -0.6 -0.4 -1.5 -0.5 -1.0 -0.7 -0.0 -1.5 1.0 1.4 0.6 -0.1
Pulse wave Arterial Stiffness index 0.9 1.1 2.8 -0.4 -1.0 -0.9 0.3 1.6 -0.2 0.0 1.5 -0.9 1.5 -1.0 -1.7 -1.0 -0.2
Impedance of arm (left) 1.2 5.8 17.8 -1.5 2.8 4.2 2.7 1.1 2.5 2.3 2.6 2.4 1.4 1.9 2.5 -0.8 2.7
Arm fat mass (right) 0.1 0.5 1.5 -0.8 -0.8 0.4 0.3 0.9 -0.1 0.2 0.6 -0.1 0.6 -1.2 -1.1 -0.8 0.3
Trunk predicted mass 0.0 0.2 1.0 -0.6 -0.4 -0.5 1.0 0.6 0.7 -0.1 0.4 -0.2 0.3 -0.2 0.0 -0.6 0.4
Standing height 0.6 6.2 14.0 -1.8 2.2 3.4 3.7 1.6 3.0 2.0 2.7 2.0 1.3 1.8 2.9 -2.0 2.8
Length of working week for main job 1.1 1.2 5.2 1.3 -0.1 0.0 -0.8 -1.4 -0.8 -0.6 -2.3 0.1 -1.7 0.7 1.0 1.3 -0.4
Exposure to tobacco smoke at home 0.5 0.5 1.4 -0.7 1.2 0.1 1.0 1.1 1.1 0.3 0.1 -0.2 0.9 -0.6 -0.3 -0.1 0.7
Breastfed as a baby 1.5 1.8 5.5 0.1 -1.2 -1.7 -0.9 0.9 -0.6 -2.3 -1.2 -1.4 0.7 -1.0 -1.5 1.1 -2.4
Tense / ‘highly strung’ 0.5 0.9 3.6 1.0 1.2 0.3 -0.7 -1.9 -0.9 1.1 -0.7 -0.9 -1.3 0.1 0.3 0.2 0.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.4 0.6 2.0 -0.8 0.4 -0.5 -0.3 0.6 0.2 0.2 -0.6 0.8 0.7 -1.4 -0.8 0.9 -1.4
Hair/balding pattern: Pattern 4 0.2 0.5 2.9 -0.6 -0.7 0.2 -0.2 0.5 -0.2 -0.3 0.3 1.7 0.8 -0.8 -0.7 0.2 -0.9
Birth weight of first child 4.2 7.5 18.5 4.1 -2.4 -1.4 -3.2 -4.1 -3.0 -3.0 -1.8 -2.4 -4.3 1.9 0.9 1.6 -1.3
Peak expiratory flow (PEF) 0.9 2.0 6.0 2.4 -0.7 -0.3 -1.4 -2.0 -1.4 -1.2 -1.8 0.6 -2.1 0.8 1.0 1.8 -0.4
Pulse wave reflection index 1.2 1.5 4.3 -0.5 -0.3 -1.8 -0.1 1.8 -0.2 -0.6 0.8 -1.1 1.8 -1.8 -2.1 -1.0 -0.5
Ever highly irritable/argumentative for 2 days 1.6 1.9 5.3 0.6 -1.3 -1.0 -1.4 0.5 -1.6 -1.4 -1.2 -0.6 0.8 -1.9 -2.2 -0.8 -2.3
Loud music exposure frequency 0.5 0.5 2.0 0.1 -0.1 -0.3 -1.4 -0.9 -1.2 0.1 -0.7 -0.7 -0.6 -0.6 -0.1 0.7 -0.8
Qualifications: O levels/GCSEs or equivalent 2.2 3.5 7.0 -2.5 1.7 2.3 2.0 1.6 2.7 1.9 1.6 2.4 1.9 0.0 1.8 -0.4 1.4
Mouth/teeth dental problems: Bleeding gums 1.4 1.8 8.2 -1.1 -1.3 -1.3 -0.6 0.7 -0.7 -0.8 -0.3 -0.6 0.4 -2.9 -1.6 -0.7 -2.5
Blood clot in the leg (DVT) 2.6 3.3 8.5 1.8 -0.9 -1.8 -2.9 -2.0 -2.0 -1.9 -1.7 -1.4 -2.3 -0.3 -0.2 1.8 -2.3
Medication: Paracetamol 1.7 2.8 6.6 -0.9 2.1 2.1 2.5 0.2 2.0 1.8 1.7 0.4 0.4 1.1 1.8 -1.4 2.6
Headache pain in last month 1.6 2.7 8.5 -1.9 1.3 1.4 2.4 2.9 1.8 0.4 1.5 1.1 2.2 -1.7 -0.5 -1.1 0.9
Medication for cholesterol, blood pressure or diabetes 0.5 0.8 4.6 0.3 1.1 0.1 0.5 -0.7 0.9 -0.5 0.5 1.5 -0.9 0.5 2.1 0.5 -0.1
Glaucoma (self-reported) 2.1 2.4 7.7 2.2 -0.2 0.6 -1.8 -2.8 -2.0 0.8 -1.2 -0.4 -2.5 1.6 1.2 1.0 0.1
Gout (self-reported) 0.9 1.3 4.8 1.8 0.4 -0.8 -0.2 -1.4 -0.2 -0.6 -2.1 -0.4 -1.3 0.8 0.2 2.2 -0.2
Hypothyroidism/myxoedema (self-reported) 0.3 0.6 1.7 0.6 0.1 -0.1 -0.5 -1.1 0.0 -0.6 -1.3 -0.3 -1.0 1.1 1.2 1.0 0.2
Medication: Amlodipine 2.0 2.8 8.0 -2.8 1.4 1.8 1.8 2.4 1.3 1.1 1.4 1.2 2.2 -1.6 -1.5 -0.7 0.2
Medication: Ventolin 100micrograms inhaler 0.7 1.0 2.8 -1.2 -0.0 0.4 0.7 1.5 0.2 0.4 0.7 0.2 1.4 -1.7 -1.4 -1.1 -0.2
Birth weight 4.0 8.7 15.5 3.9 -2.5 -3.4 -2.9 -3.4 -3.9 -3.4 -3.2 -2.1 -3.7 0.1 -0.6 1.1 -3.5
Chronic bronchitis/emphysema (mother) 0.1 0.1 0.5 0.4 0.2 0.2 0.0 -0.0 0.3 0.4 0.3 -0.4 0.3 0.2 -0.7 -0.6 0.6
High blood pressure (siblings) 1.6 2.4 5.6 -1.9 1.7 0.8 0.8 2.0 0.4 0.6 1.7 -1.4 2.4 -1.8 -1.3 -2.2 0.7
Forced vital capacity (FVC), Best measure 0.5 1.9 4.2 -1.4 1.4 1.4 2.0 0.7 1.3 1.1 1.8 1.6 0.8 0.4 1.5 -1.6 1.2
Body fat percentage 0.2 0.7 2.6 -1.1 -0.4 1.6 0.6 0.8 0.4 1.1 0.8 0.4 0.8 -0.8 -0.4 -0.8 1.1
Leg fat percentage (right) 0.1 0.5 2.5 -0.3 -1.6 0.7 -0.1 0.6 -0.6 0.0 0.1 -0.2 0.4 -1.2 -1.1 -0.2 0.5
Arm fat-free mass (right) 0.0 0.2 0.8 -0.3 -0.5 -0.9 0.4 0.4 0.2 -0.4 0.0 -0.4 0.1 -0.5 -0.3 -0.1 0.0
Exposure to tobacco smoke outside home 2.9 3.8 7.6 -2.5 0.9 2.0 2.0 2.0 1.9 2.8 2.4 2.2 2.2 -0.5 0.3 -1.7 2.2
Comparative body size at age 10 0.6 1.6 9.1 0.6 -0.3 -3.0 -0.7 -0.7 -0.4 -2.3 -0.7 -1.2 -1.0 -0.2 -0.6 0.8 -1.6
Number of full brothers 0.6 0.7 3.9 -0.3 0.7 1.1 2.0 0.8 1.0 -0.6 -0.3 0.0 0.6 -0.1 0.4 -1.2 0.9
Worry too long after embarrassment 0.3 0.6 1.9 -0.9 1.4 0.9 0.3 0.8 0.4 0.2 1.1 0.1 0.8 -0.4 0.0 1.2 0.4
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.6 2.7 0.3 -0.8 -0.5 -0.9 0.5 -0.8 -0.0 -0.7 -1.6 0.8 -0.7 -1.3 0.4 -0.1
Wheeze or whistling in the chest in last year 0.7 1.2 5.9 -1.2 0.0 0.6 0.3 1.1 -0.3 0.6 0.3 0.3 1.2 -1.3 -1.8 -2.4 -1.1
Number of children fathered 0.6 0.7 2.0 0.5 -0.9 -0.3 -0.6 0.5 -1.3 -1.4 -0.3 -1.0 -0.0 -1.3 -1.1 -0.0 -0.5
Reason for reducing amount of alcohol drunk: Health precaution 2.0 2.4 5.0 1.3 -2.0 -0.8 -2.0 -0.4 -1.8 -2.2 -1.9 -1.9 -0.6 -1.0 -1.4 0.9 -1.9
Age at first live birth 0.3 0.5 1.6 1.3 -0.7 0.2 -0.1 -0.5 -0.9 -1.1 -0.1 -0.8 -0.8 0.8 0.5 -0.0 -0.6
Pulse wave peak to peak time 0.9 1.0 3.0 0.4 1.1 1.1 -0.1 -1.5 0.3 0.1 -1.1 0.8 -1.5 1.1 1.7 0.7 0.4
Health satisfaction 0.7 0.9 2.8 -0.5 -0.3 -0.8 0.1 1.0 -0.5 0.7 0.1 -0.5 1.2 -1.7 -1.6 -1.3 -0.8
Shortness of breath walking on level ground 0.1 0.1 0.3 -0.6 0.3 0.5 -0.1 0.4 -0.3 0.3 -0.1 -0.0 0.3 -0.2 0.3 0.3 0.2
Qualifications: College or University degree 0.1 0.3 1.5 0.3 0.1 0.3 -0.1 -0.6 0.1 -0.4 -1.2 0.2 -0.5 0.7 1.1 0.5 -0.2
Eye problems/disorders: None of the above 2.1 2.4 8.3 -1.3 0.7 0.7 2.0 0.5 2.1 0.5 1.2 2.9 0.8 2.1 2.0 0.2 1.9
Mouth/teeth dental problems: Loose teeth 1.2 1.4 3.9 -0.7 1.6 1.8 1.1 -0.7 0.8 2.0 -0.1 1.1 -0.2 0.2 1.5 -0.9 1.8
Emphysema/chronic bronchitis 0.7 0.8 2.2 -1.0 -0.2 0.6 0.5 1.5 -0.2 1.2 0.5 -0.6 1.3 -0.5 -1.3 -1.0 0.4
Medication for pain relief, constipation, heartburn 1.6 2.8 8.1 1.8 -1.7 -1.9 -2.9 -0.9 -2.1 -2.2 -1.9 -0.2 -0.7 -0.2 -1.7 1.2 -1.5
Neck or shoulder pain in last month 0.4 0.5 2.2 -0.2 -0.0 1.1 0.6 0.8 0.7 0.0 0.6 -0.9 0.4 0.9 0.3 0.4 1.5
Medication: Blood pressure 0.7 1.3 6.3 -1.0 -1.1 -0.5 0.3 1.6 -0.6 0.2 0.0 -0.9 1.8 -1.0 -2.5 -1.1 -0.2
Angina (self-reported) 2.2 2.9 8.6 0.3 -2.9 -1.4 -1.9 -0.2 -1.7 -1.3 -1.3 -1.1 -0.5 -2.8 -2.1 -0.6 -2.4
Migraine (self-reported) 1.0 1.3 4.8 -0.5 2.2 1.5 2.1 1.1 1.4 0.5 0.3 -0.0 0.7 0.1 0.8 -0.8 1.1
Medication: Ibuprofen 1.9 2.2 5.2 -1.8 1.4 0.8 2.0 1.9 1.4 2.3 2.2 0.3 1.4 -0.3 0.6 0.2 1.7
Medication: Allopurinol 0.7 0.9 3.3 1.6 -0.2 -1.1 -0.1 -0.9 -0.2 -0.6 -1.7 -0.4 -0.8 0.9 -0.4 1.8 0.3
Medication: Omeprazole 0.5 0.6 2.2 0.7 -0.7 0.4 0.6 -0.4 -0.3 0.6 0.0 -1.3 -0.9 1.0 0.2 -0.2 1.5
Medication: Seretide 50 evohaler 0.6 0.7 2.1 -0.9 -0.1 0.4 0.6 0.5 0.4 1.3 1.1 0.7 0.8 -0.6 -1.0 -1.4 0.0
Mean time to correctly identify matches 0.9 1.8 4.6 -0.5 0.2 1.6 1.6 0.7 1.1 1.8 1.7 0.7 1.1 1.6 0.5 -2.1 1.5
Heart disease (mother) 2.5 3.1 8.6 1.3 -1.8 -1.7 -1.9 -0.4 -2.1 -1.9 -0.9 -1.2 -0.6 -2.9 -2.2 -0.2 -2.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 2.1 0.4 0.4 1.4 -0.3 -1.5 -0.1 1.3 -0.3 0.9 -1.0 0.3 0.8 0.1 0.8
Whole body fat mass 0.1 0.5 1.0 -0.9 -0.6 1.0 0.6 0.9 0.2 0.5 0.5 0.3 0.7 -1.0 -0.6 -0.8 0.6
Leg fat mass (right) 0.1 0.3 1.7 -0.1 -1.3 0.3 -0.3 0.4 -0.7 -0.2 -0.1 -0.2 0.2 -1.0 -1.0 -0.2 0.2
Arm predicted mass (right) 0.1 0.3 0.8 -0.9 -0.1 -0.6 0.9 0.8 0.7 0.1 0.5 -0.1 0.6 -0.6 -0.2 -0.3 0.3
Pulse rate, automated reading 0.4 1.2 4.3 0.5 -0.9 -2.1 -0.8 -0.3 -0.8 -1.1 -1.2 -1.4 -0.2 -0.7 -0.9 1.3 -1.5
Alcohol intake frequency. 0.7 1.6 7.2 -0.5 0.7 1.8 1.3 0.1 0.2 2.0 0.4 1.0 0.0 -0.5 0.3 -2.7 2.1
Comparative height size at age 10 0.3 1.8 3.1 -1.2 0.8 1.3 1.5 1.8 1.4 1.5 1.4 0.7 1.7 0.0 0.4 -1.8 1.6
Number of full sisters 1.9 2.3 7.6 -2.2 -0.1 -1.1 0.2 2.7 0.7 -0.2 1.2 -0.0 2.8 -2.0 -1.8 0.2 -1.4
Suffer from ‘nerves’ 0.5 0.7 3.0 0.6 -0.9 0.6 -0.6 -0.5 -1.3 0.6 -0.4 -0.4 -0.3 -1.1 -0.9 -1.7 -0.8
Overall health rating 1.7 3.7 7.6 -1.8 2.4 2.5 2.7 1.6 1.4 2.8 1.6 1.6 1.8 -0.8 0.1 -2.5 1.3
Chest pain or discomfort 0.5 0.8 3.6 -0.7 0.6 1.9 0.4 0.3 0.5 1.4 -0.6 0.3 0.4 -0.5 0.1 -1.6 0.6
Had major operations 1.0 1.2 3.9 2.0 -1.8 -0.3 -0.7 -0.5 -0.9 -1.8 -0.7 -1.2 -1.0 1.1 0.2 0.3 -0.2
Age at last live birth 1.4 2.1 5.0 1.8 -0.9 -0.0 -1.0 -2.2 -1.1 0.5 -2.1 -0.5 -2.1 2.2 1.6 1.2 0.1
Family relationship satisfaction 0.9 1.1 4.6 0.0 -1.3 -1.3 -0.6 0.7 -0.6 -1.1 0.3 -1.8 0.5 -0.9 -2.1 0.0 -1.1
Leg pain on walking 0.1 0.1 0.9 -0.1 0.2 0.3 0.0 -0.2 -0.3 0.8 0.9 0.0 -0.3 -0.1 0.0 0.2 -0.2
Qualifications: NVQ or HND or HNC or equivalent 2.0 2.4 8.9 2.1 -2.0 -1.4 -2.1 -1.0 -1.5 -1.5 -0.9 -1.6 -1.1 0.4 -0.4 3.0 0.5
Commuting to job workplace: Car/motor vehicle 1.4 1.6 5.0 0.3 0.0 -2.2 -1.5 0.4 -1.2 -1.9 -1.6 -0.6 0.3 -1.1 -1.9 0.9 -1.1
Illness, injury, bereavement, stress in last 2 years 0.4 0.5 2.1 -0.2 0.6 0.6 0.6 -0.0 0.1 1.4 1.3 -1.0 0.1 0.7 0.2 -0.7 0.4
Medication: Aspirin 0.9 1.2 4.3 -0.6 -0.8 -0.4 -0.4 0.5 -0.7 -0.3 -0.9 -1.3 0.5 -2.1 -1.2 -1.9 -1.6
Supplements: Vitamin C 0.9 1.1 5.5 1.8 -0.7 -1.0 -0.2 -1.1 -0.7 -0.4 0.2 -2.3 -1.3 1.1 -0.2 -0.3 0.3
Knee pain experienced in last month 2.7 4.2 10.4 -2.4 0.2 1.2 2.4 3.2 1.8 0.9 2.7 1.1 3.0 -1.7 -1.5 -2.4 1.9
Hypertension (Self-reported) 1.5 4.1 11.0 -2.5 0.5 1.0 1.0 3.1 -0.2 1.7 1.8 0.1 3.3 -3.0 -3.0 -1.9 -0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.2 0.3 0.8 0.9 -0.7 -0.6 -0.5 -0.5 -0.1 -0.7 -0.6 -0.2 -0.6 0.1 -0.0 0.3 -0.3
Illnesses of father: Heart disease 3.4 4.6 15.7 -2.7 -1.2 -1.0 -0.3 3.5 -0.1 0.5 0.7 -0.2 3.5 -4.0 -3.5 0.4 -1.4
Illnesses of siblings: Diabetes 1.9 2.3 4.7 -1.5 1.7 1.7 1.7 1.2 1.3 1.3 2.2 1.3 1.6 0.9 0.5 -1.8 1.6
Smoking status: Previous 0.4 0.7 3.8 0.0 0.6 0.4 0.5 0.0 -0.0 0.5 0.7 -0.4 -0.3 1.7 0.8 0.3 2.0
Forced expiratory volume in 1-second (FEV1), predicted 0.5 1.1 3.8 -1.0 1.0 1.7 1.9 1.2 1.3 0.4 0.1 0.8 0.9 -0.7 0.2 -1.4 0.2
Whole body fat-free mass 0.0 0.2 0.8 -0.6 -0.1 -0.3 0.9 0.6 0.6 0.2 0.6 0.2 0.3 -0.2 -0.0 -0.4 0.4
Leg fat-free mass (right) 0.0 0.2 0.4 -0.6 0.1 -0.3 0.6 0.5 0.4 0.6 0.6 0.7 0.2 -0.5 -0.2 -0.2 -0.0
Arm fat percentage (left) 0.1 0.4 1.2 -0.7 -0.4 0.6 0.1 0.8 -0.0 0.3 0.4 0.3 0.7 -1.1 -1.1 -0.2 0.4
Average weekly red wine intake 1.7 2.5 4.5 2.1 -1.5 -0.7 -2.0 -1.1 -1.9 -2.1 -2.0 -1.5 -1.7 -0.9 -0.2 1.8 -1.0
Handedness (chirality/laterality): Left-handed 0.5 0.6 1.7 1.0 -0.7 -0.9 -0.5 -1.3 -0.9 0.4 -0.7 -0.5 -1.3 0.2 0.1 0.7 0.1
Mood swings 0.2 0.4 2.4 0.7 0.0 -0.1 -0.0 -0.8 0.1 -0.1 -0.2 -1.2 -0.9 0.2 0.2 1.6 -0.3
Loneliness, isolation 1.6 2.2 6.5 -1.5 2.1 1.4 1.0 0.9 1.2 1.7 1.9 0.7 1.2 0.9 0.9 -1.4 2.5
Long-standing illness, disability or infirmity 0.5 0.7 2.9 -0.6 1.2 1.7 0.8 0.8 0.4 0.9 0.2 0.4 0.6 -0.4 -0.2 -1.2 0.7
Ever had bowel cancer screening 3.5 4.1 8.6 2.9 -1.5 -2.0 -2.4 -2.2 -2.3 -2.2 -2.2 -0.8 -2.1 1.3 0.0 2.6 -1.9
Diabetes diagnosed by doctor 0.6 1.0 4.1 -0.8 1.3 2.0 0.3 -0.6 0.8 1.1 -1.4 0.7 -0.4 1.1 1.2 -0.7 -0.2
Ever had stillbirth, spontaneous miscarriage or termination 0.7 0.8 2.1 0.6 -0.5 1.0 0.2 -1.0 -0.7 1.4 -0.6 -0.0 -0.7 1.5 1.0 0.1 1.3
Friendships satisfaction 0.4 0.5 2.4 -0.5 -0.3 1.6 0.9 0.3 0.8 0.6 0.8 0.7 0.4 0.1 0.0 -1.1 -0.2
Qualifications: nursing, teaching 0.6 0.9 2.4 -1.0 0.3 1.0 0.6 0.5 1.1 -1.0 -0.9 1.3 -0.2 1.0 1.6 1.3 0.7
Commuting to job workplace: Walk 1.3 1.4 2.7 -0.3 1.2 1.2 1.6 -0.5 1.1 1.5 1.6 -0.2 -0.6 0.8 1.6 -0.8 1.6
Eye problems/disorders: Cataract 1.6 1.8 7.0 -0.5 -0.6 -1.0 -0.3 1.6 -0.3 -1.2 -0.2 -1.2 1.1 -2.6 -2.1 -0.9 -2.1
Mouth/teeth dental problems: Mouth ulcers 2.8 4.4 10.7 -2.1 0.9 2.3 3.0 1.8 1.8 2.3 3.0 1.9 2.0 -0.3 0.6 -3.3 1.6
Medication for cholesterol 0.8 1.2 3.8 1.1 -0.1 -0.9 0.1 -1.2 0.1 -0.5 -1.0 1.1 -1.3 2.0 1.3 1.5 1.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.3 1.2 -0.1 -0.2 0.0 -0.2 0.7 0.1 -1.1 0.1 0.3 0.2 -0.8 -0.2 0.8 -0.8
Back pain experienced in last month 0.8 1.1 3.1 1.7 -0.8 -0.7 -1.2 -0.4 -1.7 -0.9 -0.3 -1.7 -0.3 -0.3 -1.5 0.2 -0.8
Mineral and other dietary supplements 0.9 1.3 5.7 -1.6 -1.0 -1.4 -0.7 0.6 0.1 -0.0 -0.8 0.2 0.9 -2.4 -1.3 -0.5 -1.5
Breast cancer (self-reported) 1.3 1.6 4.1 0.1 -1.5 -2.0 -0.1 1.4 -0.2 -1.6 -1.1 -1.6 0.9 -1.4 -1.9 0.6 -0.6
Asthma (self-reported) 3.4 6.8 19.5 -4.4 1.7 1.3 2.3 3.6 1.7 2.5 2.4 2.5 3.8 -2.3 -1.9 -2.9 0.2
Osteoporosis (self-reported) 0.9 1.1 3.8 -0.1 0.8 1.7 0.3 -1.0 -0.0 1.0 -1.5 1.5 -0.8 -0.7 0.4 -2.0 -0.2
Osteoarthritis (self-reported) 0.3 0.4 1.3 -0.5 1.1 0.7 0.9 0.9 0.6 0.4 -0.4 1.0 0.7 -0.4 -0.3 0.1 0.1
Medication: Aspirin 1.4 1.9 6.0 -0.2 -1.1 -0.4 -0.8 0.2 -1.3 -0.8 -1.4 -1.5 0.1 -2.5 -1.4 -2.1 -2.2
Medication: Gliclazide 0.5 0.5 1.5 0.3 0.8 0.3 -0.1 -1.0 0.7 0.1 -0.4 0.1 -1.0 1.2 1.1 0.9 0.5
Illnesses of father: None of the above (group 1) 1.2 1.5 5.1 1.7 0.6 -0.4 -0.3 -1.9 -0.3 -1.0 -1.1 0.2 -2.1 2.3 1.3 0.7 0.5
Smoking status: Current 0.4 0.7 3.5 -1.1 -0.5 -0.8 -0.5 0.2 0.4 -0.6 -0.9 0.1 0.2 -1.4 -0.4 0.2 -1.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.1 2.3 4.8 2.0 -1.1 -0.9 -2.0 -2.1 -2.0 -2.2 -2.0 -1.4 -1.7 -0.5 0.0 0.2 -0.8
Whole body water mass 0.0 0.2 0.7 -0.6 -0.1 -0.4 0.8 0.7 0.5 0.1 0.6 0.1 0.4 -0.4 -0.2 -0.5 0.3
Leg predicted mass (right) 0.0 0.2 0.4 -0.6 0.1 -0.3 0.6 0.5 0.4 0.5 0.6 0.6 0.2 -0.6 -0.3 -0.2 -0.1
Arm fat mass (left) 0.1 0.5 1.4 -1.0 -0.5 0.4 0.4 1.1 0.1 0.2 0.7 0.1 0.9 -1.2 -1.1 -0.5 0.4
Number of self-reported non-cancer illnesses 1.1 1.9 8.2 -0.3 0.5 0.9 0.1 1.3 -1.2 0.7 -0.2 0.4 1.4 -2.1 -2.9 -2.2 -1.4
Average weekly champagne plus white wine intake 0.5 0.7 3.0 0.5 0.8 1.1 0.6 -0.6 0.6 -0.1 0.5 -0.4 -0.8 1.1 1.7 -0.6 0.9
Miserableness 0.6 1.0 2.8 -1.2 0.8 0.3 1.2 1.5 0.9 1.2 1.7 -0.6 1.3 -0.5 -0.8 0.1 0.4
Guilty feelings 1.4 2.2 7.2 0.5 -1.1 -1.9 -1.3 0.6 -1.6 -1.6 -0.3 -2.0 0.6 -1.6 -2.7 -1.1 -1.6
Wears glasses or contact lenses 0.4 0.5 1.5 0.2 0.1 -0.5 -0.9 -0.8 -0.8 0.8 -1.2 -0.0 -0.5 0.2 -0.2 1.2 0.4
Ever taken oral contraceptive pill 1.2 1.3 5.2 -2.3 -0.1 -0.1 0.4 1.8 0.6 1.3 0.5 -0.8 1.9 -1.2 -1.0 -0.7 0.4
Hearing aid user 2.5 2.8 7.4 -2.4 1.2 0.1 2.6 2.5 2.7 0.1 1.0 -0.6 2.4 -0.8 0.4 -1.7 0.4
Mother’s age at death 3.0 3.8 7.2 2.7 -0.5 -2.3 -2.0 -2.4 -2.3 -2.7 -1.9 -2.3 -2.3 0.5 -0.5 0.6 -1.6
Financial situation satisfaction 1.0 1.3 2.8 -1.2 -0.3 0.6 0.8 1.7 0.4 1.1 1.6 1.0 1.7 -0.6 -1.2 -1.6 0.7
Tinnitus: Yes, now most or all of the time 0.3 0.3 1.2 0.9 -0.2 -0.4 -0.6 -0.1 -0.7 -0.8 -0.5 -0.9 -0.2 -0.0 -0.2 1.1 0.1
Commuting to job workplace: Public transport 0.4 0.5 2.0 1.4 -0.8 -0.1 -0.5 -1.1 -0.9 0.2 -0.5 -0.4 -1.1 -0.3 0.0 -0.2 -0.4
Eye problems/disorders: Glaucoma 3.3 4.0 9.0 3.0 -0.5 0.2 -2.8 -3.0 -2.8 -0.3 -2.2 -1.4 -2.9 1.2 0.6 2.1 -0.6
Medication: Blood pressure 0.9 1.7 4.8 -1.2 0.3 1.6 0.3 1.3 -0.4 1.9 1.4 -0.8 1.6 -2.2 -1.4 -1.7 -0.1
Pain type(s) experienced in last month: Hip pain 0.5 0.6 5.1 0.4 2.3 0.6 0.8 0.0 0.2 0.4 0.0 0.3 -0.1 0.1 0.6 -1.0 0.9
Supplements: Fish oil (including cod liver oil) 0.4 0.5 2.7 1.0 0.2 0.1 0.3 -0.3 -0.0 -0.8 0.9 -0.4 -0.7 1.6 0.5 0.2 0.3
High cholesterol (Self-reported) 0.5 0.8 4.5 0.7 -0.3 -0.8 -0.9 -0.1 -1.4 0.1 -0.4 -1.6 0.2 -0.6 -2.1 -0.1 -0.4
Medication: Bendroflumethiazide 0.8 1.3 3.6 -1.6 1.0 0.5 1.0 1.8 0.5 1.6 0.8 -0.8 1.9 -1.1 -0.9 -0.4 0.5
Medication: Paracetamol 2.1 3.2 7.7 -1.2 2.1 2.8 2.5 0.5 2.0 2.1 1.6 1.1 0.6 0.4 1.5 -1.8 2.7
Medication: Lisinopril 0.6 0.7 2.0 1.4 -1.2 -0.3 -0.4 -1.3 -0.9 -0.5 -1.0 -0.5 -1.4 0.1 -0.3 -0.3 -0.6
Medication: Atorvastatin 0.5 0.6 2.5 -0.9 -0.7 -0.2 -0.4 0.6 -0.1 -0.2 -1.6 -0.6 0.5 -1.2 -0.9 -0.1 -0.8
Illnesses of father: High blood pressure 2.7 3.4 10.8 -2.1 0.6 1.3 1.4 3.2 1.0 0.8 2.9 0.2 3.3 -1.7 -1.6 -0.7 1.3
Alcohol drinker status: Never 0.6 0.7 2.6 -0.8 -0.2 -1.1 0.1 0.9 0.2 0.8 -0.2 -1.0 1.0 -1.4 -0.8 -1.6 -0.0
Ever smoked 0.4 0.6 1.6 -1.2 -0.3 0.5 0.9 0.6 1.1 -0.5 -0.0 0.8 0.2 1.2 0.9 0.8 0.8
Basal metabolic rate 0.0 0.2 0.6 -0.7 -0.3 -0.2 0.8 0.7 0.5 0.2 0.5 0.1 0.4 -0.5 -0.2 -0.4 0.4
Leg fat percentage (left) 0.1 0.5 2.7 -0.3 -1.6 0.4 -0.3 0.4 -0.7 0.3 0.0 -0.4 0.2 -1.2 -1.1 -0.2 0.4
Arm fat-free mass (left) 0.0 0.2 0.3 -0.6 -0.5 -0.4 0.6 0.5 0.4 0.1 0.3 -0.3 0.2 -0.5 -0.2 -0.5 0.4
Number of operations (self-reported) 0.4 0.6 2.5 0.1 -1.2 -0.3 -0.7 -0.1 -0.7 -1.3 -1.6 -0.4 -0.3 -1.2 -0.2 -0.5 -0.4
Average weekly beer plus cider intake 1.2 1.8 4.7 -1.4 0.8 -1.3 0.7 2.0 0.6 -0.8 1.7 -1.9 2.2 -0.2 -1.9 -0.6 -0.1
Irritability 0.2 0.4 2.0 0.2 0.8 -0.9 -0.0 -0.8 -0.2 -0.0 -0.3 -1.4 -0.8 -0.1 0.1 -0.2 -0.2
Risk taking 0.1 0.1 0.5 -0.1 0.1 0.4 -0.2 0.3 -0.1 0.1 -0.3 0.1 0.4 -0.5 -0.7 0.0 0.3
Ever had prostate specific antigen (PSA) test 0.6 0.7 2.5 0.8 0.5 1.6 0.7 -0.4 0.2 0.5 0.2 0.3 -0.7 1.4 0.9 0.5 1.5
Fractured/broken bones in last 5 years 1.6 2.0 11.6 -1.6 0.1 1.4 1.6 1.0 0.1 1.3 1.4 0.6 1.1 -1.5 -0.6 -3.4 0.9
Age started oral contraceptive pill 0.8 0.9 7.2 0.4 0.2 -0.6 -0.5 0.3 -0.7 -0.8 0.7 -2.7 0.1 -0.5 -1.1 -1.3 0.5
Diastolic blood pressure, automated reading 1.2 3.8 14.1 -0.2 -2.7 -1.4 -1.1 1.8 -1.7 -0.8 -0.5 -2.1 1.7 -3.8 -3.2 -0.7 -1.9
Ever depressed for a whole week 0.4 0.5 1.8 -0.3 0.4 -1.1 -0.8 0.7 -0.7 -0.1 -0.0 0.8 0.8 -0.4 -0.2 1.4 -0.8
Unable to work because of sickness or disability 1.0 1.3 5.2 -0.1 -2.3 0.5 -0.6 -0.1 -1.2 0.6 -1.1 1.8 0.1 -1.3 -0.7 -1.1 -1.4
Commuting to job workplace: Cycle 1.1 1.3 5.5 0.6 0.6 1.0 0.5 -1.7 0.2 1.5 -0.9 -0.8 -1.5 1.1 2.3 0.6 0.7
Myopia 1.0 1.5 4.2 -0.0 0.3 1.8 1.1 -1.0 1.1 1.0 0.2 2.0 -0.8 1.8 1.9 -0.5 0.9
Vascular/heart problems diagnosed by doctor 1.8 5.0 15.8 2.6 -0.4 -0.5 -0.7 -3.4 0.2 -0.8 -1.5 0.5 -3.5 4.0 3.6 2.2 1.4
Cholesterol lowering medication 1.1 1.6 7.2 -0.6 0.7 0.4 0.5 1.1 -0.4 -0.6 0.2 -0.9 1.1 -2.2 -1.8 -2.7 -1.3
Medication: Omeprazole (e.g. Zanprol) 0.9 1.0 4.9 0.3 -0.2 1.2 1.4 -0.5 0.3 1.1 0.4 -0.1 -1.0 1.5 1.0 -0.3 2.2
Pain experienced in last month 1.0 1.6 5.9 0.5 0.2 -0.8 -0.7 -2.4 -0.1 -0.2 -1.8 1.2 -2.0 1.4 1.6 1.3 -0.7
Supplements: Calcium 2.3 2.5 6.1 1.4 2.3 1.3 1.2 -1.8 0.8 0.7 -0.6 0.4 -1.9 2.5 2.0 -0.2 2.3
Basal cell carcinoma (self-reported) 0.8 1.0 3.4 0.5 0.1 -1.4 -0.5 -0.1 -0.2 -1.9 -1.0 -1.5 -0.3 -0.6 -1.1 -0.0 -1.7
Heart attack/myocardial infarction (self-reported) 2.5 3.3 11.3 0.8 -1.3 -2.2 -1.4 0.3 -1.5 -2.9 -2.4 -3.4 -0.0 -1.7 -1.6 -0.6 -1.7
Deep venous thrombosis (DVT) (self-reported) 3.4 4.4 11.4 2.0 -1.3 -2.1 -3.4 -2.3 -2.5 -2.1 -2.0 -2.0 -2.6 -0.4 -0.4 1.8 -2.4
Heart disease (siblings) 0.7 0.9 2.1 1.0 -1.4 -1.4 -0.7 0.2 -0.9 -1.2 -0.3 -1.3 0.0 -0.8 -1.3 0.2 -0.7
Alcohol drinker status: Previous 0.9 1.0 3.0 -0.9 0.3 1.5 1.7 0.3 0.9 1.1 0.6 0.2 0.0 0.4 0.7 -1.3 1.7
Pack years of smoking 0.8 1.2 3.1 -1.6 -0.8 -0.7 0.4 1.5 0.5 -0.3 -0.2 -1.7 1.8 -1.1 -0.9 -1.6 -0.1
Impedance of whole body 0.9 4.7 16.0 -1.4 2.2 4.0 2.4 0.9 2.4 2.1 2.1 1.8 1.2 1.8 2.5 -0.9 2.8
Leg fat mass (left) 0.1 0.3 1.8 -0.2 -1.3 0.2 -0.3 0.3 -0.6 0.1 -0.1 -0.3 0.1 -0.9 -0.9 -0.2 0.3
Arm predicted mass (left) 0.1 0.4 0.8 -0.8 -0.8 -0.6 0.6 0.9 0.3 0.0 0.4 -0.5 0.6 -0.8 -0.6 -0.6 0.4