Best TWAS P=1.89e-09 · Best GWAS P=2.23e-09 conditioned to 0.0092
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CDC42 | 0.07 | 0.01 | enet | 10 | 0.01 | 0.0095 | 5.9 | 6.0 | 1.9e-09 | 0.68 | 0.00 | 0.79 | TRUE |
2 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | HSPC157 | 0.19 | 0.05 | lasso | 1 | 0.04 | 0.0350 | 5.2 | 5.2 | 1.8e-07 | 0.85 | 0.01 | 0.50 | FALSE |