Best TWAS P=7.47e-09 · Best GWAS P=1.18e-07 conditioned to 0.398
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | TMEM200B | 0.09 | 0.12 | lasso | 12 | 0.12 | 5.9e-15 | -5.2 | -5.2 | 1.8e-07 | 0.98 | 0.01 | 0.99 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TMEM200B | 0.03 | 0.02 | blup | 38 | 0.02 | 1.0e-03 | -4.0 | -5.8 | 7.5e-09 | 0.84 | 0.01 | 0.75 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | EPB41 | 0.07 | 0.05 | lasso | 3 | 0.06 | 1.8e-06 | -5.1 | 5.8 | 8.0e-09 | -0.75 | 0.01 | 0.98 | FALSE |