Best TWAS P=1.97e-09 · Best GWAS P=6.87e-07 conditioned to 0.418
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | CCDC93 | 0.37 | 0.10 | lasso | 9 | 0.22 | 2.4e-16 | -4.2 | 6.0 | 2.0e-09 | 0.74 | 0.02 | 0.97 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CCDC93 | 0.02 | 0.02 | lasso | 5 | 0.01 | 9.3e-04 | 4.9 | 5.2 | 2.4e-07 | 0.99 | 0.00 | 0.88 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CCDC93 | 0.04 | 0.01 | enet | 6 | 0.02 | 3.5e-03 | 4.9 | 5.1 | 2.7e-07 | 0.90 | 0.00 | 0.92 | FALSE |