[Hub]/) : Traits : Intelligence (Savage-Jansen 2018) :

chr4:17,104,059-18,507,692

Best TWAS P=5.6e-13 · Best GWAS P=5.6e-13 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta DCAF16 0.10 0.01 enet 6 0.02 4.7e-02 -6.8 7.0 3.1e-12 -0.84 0.04 0.85 FALSE
2 GTEx Breast Mammary Tissue DCAF16 0.12 0.08 lasso 4 0.10 6.4e-06 3.5 5.4 7.3e-08 -0.57 0.05 0.87 FALSE
3 GTEx Breast Mammary Tissue (Male) DCAF16 0.24 0.03 enet 18 -0.01 4.4e-01 -6.6 6.1 1.1e-09 -0.75 0.03 0.66 FALSE
4 GTEx Spleen DCAF16 0.35 0.02 lasso 5 0.11 8.5e-04 3.6 6.0 2.1e-09 -0.61 0.07 0.43 FALSE
5 ROSMAP Brain Pre-frontal Cortex DCAF16 0.04 0.02 bslmm 379 0.01 3.9e-02 -6.6 5.6 2.6e-08 -0.85 0.06 0.80 FALSE
6 The Cancer Genome Atlas Colon Adenocarcinoma NCAPG 0.08 0.04 blup 34 0.09 1.1e-05 -7.2 -6.4 1.5e-10 0.92 0.01 0.99 FALSE
7 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma NCAPG 0.14 0.07 lasso 3 0.07 5.2e-08 -6.6 -6.5 7.6e-11 0.97 0.14 0.86 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma DCAF16 0.09 0.02 lasso 3 0.04 5.2e-05 3.7 6.2 5.1e-10 -0.70 0.17 0.58 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma NCAPG 0.02 0.03 lasso 1 0.02 9.0e-04 -7.2 -7.2 5.6e-13 1.00 0.00 0.92 TRUE
10 The Cancer Genome Atlas Prostate Adenocarcinoma DCAF16 0.04 0.04 blup 31 0.04 2.2e-05 3.6 6.0 2.3e-09 -0.63 0.27 0.23 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma NCAPG 0.02 0.02 blup 34 0.02 3.4e-03 -6.9 -6.4 1.6e-10 0.85 0.02 0.64 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma DCAF16 0.07 0.04 blup 31 0.07 4.9e-07 3.7 5.7 9.7e-09 -0.74 0.17 0.74 FALSE