Best TWAS P=1.31e-12 · Best GWAS P=2.51e-12 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PEF1 | 0.04 | 0.04 | lasso | 4 | 0.03 | 0.00028 | -5.7 | 5.7 | 9.7e-09 | -0.81 | 0.23 | 0.74 | FALSE |
| 2 | GTEx | Artery Aorta | PEF1 | 0.15 | 0.05 | lasso | 5 | 0.04 | 0.00222 | -6.6 | 7.1 | 1.3e-12 | -0.95 | 0.02 | 0.97 | TRUE |
| 3 | GTEx | Colon Sigmoid | PEF1 | 0.16 | 0.09 | lasso | 3 | 0.09 | 0.00043 | -5.7 | 6.6 | 5.3e-11 | -0.88 | 0.04 | 0.82 | FALSE |
| 4 | GTEx | Skin Sun Exposed Lower leg | PEF1 | 0.05 | 0.03 | enet | 9 | 0.02 | 0.00462 | -6.6 | 6.2 | 4.6e-10 | -0.86 | 0.02 | 0.97 | FALSE |
| 5 | METSIM | Adipose | PEF1 | 0.03 | 0.02 | enet | 17 | 0.02 | 0.00079 | -5.8 | 5.2 | 2.1e-07 | -0.59 | 0.16 | 0.63 | FALSE |
| 6 | ROSMAP | Brain Pre-frontal Cortex | PEF1 | 0.04 | 0.04 | lasso | 3 | 0.02 | 0.00042 | -5.8 | 5.4 | 6.3e-08 | -0.79 | 0.13 | 0.84 | FALSE |