[Hub]/) : Traits : Intelligence (Savage-Jansen 2018) :

chr1:31,402,148-32,762,733

Best TWAS P=1.31e-12 · Best GWAS P=2.51e-12 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PEF1 0.04 0.04 lasso 4 0.03 0.00028 -5.7 5.7 9.7e-09 -0.81 0.23 0.74 FALSE
2 GTEx Artery Aorta PEF1 0.15 0.05 lasso 5 0.04 0.00222 -6.6 7.1 1.3e-12 -0.95 0.02 0.97 TRUE
3 GTEx Colon Sigmoid PEF1 0.16 0.09 lasso 3 0.09 0.00043 -5.7 6.6 5.3e-11 -0.88 0.04 0.82 FALSE
4 GTEx Skin Sun Exposed Lower leg PEF1 0.05 0.03 enet 9 0.02 0.00462 -6.6 6.2 4.6e-10 -0.86 0.02 0.97 FALSE
5 METSIM Adipose PEF1 0.03 0.02 enet 17 0.02 0.00079 -5.8 5.2 2.1e-07 -0.59 0.16 0.63 FALSE
6 ROSMAP Brain Pre-frontal Cortex PEF1 0.04 0.04 lasso 3 0.02 0.00042 -5.8 5.4 6.3e-08 -0.79 0.13 0.84 FALSE