Best TWAS P=2.31e-14 · Best GWAS P=2.19e-15 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | CALN1 | 0.05 | 0.02 | lasso | 4 | 0.01 | 1.0e-02 | -7.6 | 7.6 | 2.3e-14 | -0.98 | 0.02 | 0.97 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | CALN1 | 0.11 | 0.08 | bslmm | 475 | 0.07 | 9.5e-10 | -6.0 | 6.2 | 6.9e-10 | -0.72 | 0.59 | 0.41 | FALSE |