[Hub]/) : Traits : Intelligence (Savage-Jansen 2018) :

chr7:43,964,217-45,583,220

Best TWAS P=1.63e-10 · Best GWAS P=4.14e-11 conditioned to 0.00226

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts ZMIZ2 0.12 0.09 lasso 4 0.06 2.3e-05 5.9 5.2 2.5e-07 0.81 0.05 0.94 FALSE
2 GTEx Muscle Skeletal OGDH 0.09 0.02 enet 12 0.03 5.4e-04 -4.2 -5.6 2.7e-08 -0.43 0.05 0.92 TRUE
3 GTEx Nerve Tibial ZMIZ2 0.12 0.06 lasso 5 0.06 5.1e-05 6.6 -6.0 1.9e-09 -0.57 0.00 1.00 FALSE
4 GTEx Thyroid H2AFV 0.15 0.04 lasso 6 0.08 1.8e-06 -4.8 -6.4 1.6e-10 -0.24 0.34 0.22 TRUE
5 NTR Blood ZMIZ2 0.08 0.06 enet 17 0.06 1.5e-18 -5.7 5.5 2.9e-08 0.38 0.14 0.86 FALSE
6 ROSMAP Brain Pre-frontal Cortex ZMIZ2 0.10 0.06 enet 15 0.07 1.3e-09 -5.4 -5.1 2.9e-07 -0.25 0.72 0.28 FALSE