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chr9:131,169,528-132,601,229

Best TWAS P=7.17e-10 · Best GWAS P=9.66e-10 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CRAT	0.08	0.08	lasso	1	0.07	7.1e-09	5.7	-5.7	1.6e-08	-0.89	0.05	0.95	FALSE
2	GTEx	Adipose Subcutaneous	PPP2R4	0.12	0.08	enet	12	0.09	4.4e-08	5.7	-6.1	1.0e-09	-0.85	0.04	0.96	FALSE
3	GTEx	Adipose Visceral Omentum	CRAT	0.13	0.09	lasso	9	0.06	5.3e-04	5.7	-5.3	1.2e-07	-0.86	0.04	0.93	FALSE
4	GTEx	Artery Aorta	CRAT	0.24	0.32	lasso	4	0.31	1.9e-17	5.7	-5.7	1.5e-08	-0.89	0.05	0.95	FALSE
5	GTEx	Artery Aorta	PPP2R4	0.18	0.08	lasso	4	0.09	1.6e-05	5.7	-5.7	1.6e-08	-0.89	0.05	0.95	FALSE
6	GTEx	Artery Coronary	CRAT	0.18	0.12	lasso	5	0.12	9.2e-05	5.7	-5.7	1.0e-08	-0.87	0.04	0.92	FALSE
7	GTEx	Artery Tibial	CRAT	0.15	0.12	lasso	5	0.10	5.6e-08	5.7	-6.0	2.0e-09	-0.92	0.04	0.96	FALSE
8	GTEx	Artery Tibial	PPP2R4	0.14	0.16	lasso	1	0.14	3.0e-11	5.7	-5.7	1.6e-08	-0.89	0.05	0.95	FALSE
9	GTEx	Brain Cerebellum	CRAT	0.35	0.27	lasso	8	0.27	1.1e-08	5.6	-6.0	1.5e-09	-0.91	0.03	0.96	FALSE
10	GTEx	Breast Mammary Tissue	PPP2R4	0.11	0.08	lasso	3	0.05	1.9e-03	5.7	-5.7	1.6e-08	-0.89	0.04	0.88	FALSE
11	GTEx	Cells EBV-transformed lymphocytes	CRAT	0.17	0.17	lasso	3	0.11	1.6e-04	5.7	-5.7	1.4e-08	-0.87	0.04	0.93	FALSE
12	GTEx	Cells Transformed fibroblasts	CRAT	0.23	0.26	lasso	5	0.26	2.1e-19	5.7	-5.8	5.3e-09	-0.89	0.04	0.96	FALSE
13	GTEx	Cells Transformed fibroblasts	RP11-247A12.1	0.07	0.04	enet	8	0.04	5.0e-04	5.9	-5.9	2.9e-09	-0.95	0.02	0.96	FALSE
14	GTEx	Colon Sigmoid	CRAT	0.21	0.06	lasso	7	0.04	1.8e-02	5.7	-6.0	2.5e-09	-0.83	0.03	0.72	FALSE
15	GTEx	Colon Transverse	CRAT	0.30	0.26	lasso	3	0.31	1.7e-15	5.7	-5.8	6.9e-09	-0.87	0.05	0.95	FALSE
16	GTEx	Colon Transverse	RP11-247A12.1	0.12	0.10	lasso	4	0.08	9.8e-05	5.7	-5.7	1.2e-08	-0.89	0.04	0.94	FALSE
17	GTEx	Esophagus Gastroesophageal Junction	CRAT	0.14	0.11	lasso	8	0.06	3.9e-03	5.7	-5.8	8.1e-09	-0.88	0.04	0.90	FALSE
18	GTEx	Esophagus Mucosa	CRAT	0.23	0.14	enet	19	0.23	2.1e-15	5.7	-5.8	7.5e-09	-0.87	0.05	0.95	FALSE
19	GTEx	Esophagus Mucosa	DOLPP1	0.21	0.18	enet	16	0.19	6.7e-13	5.9	-5.9	2.7e-09	-0.92	0.02	0.98	FALSE
20	GTEx	Esophagus Mucosa	RP11-247A12.1	0.23	0.13	enet	16	0.16	4.3e-11	5.3	-5.8	6.9e-09	-0.84	0.05	0.95	FALSE
21	GTEx	Esophagus Muscularis	CRAT	0.13	0.09	enet	7	0.11	5.4e-07	5.7	-5.9	2.7e-09	-0.91	0.04	0.96	FALSE
22	GTEx	Heart Atrial Appendage	CRAT	0.26	0.24	lasso	4	0.25	2.0e-11	5.7	-5.7	1.4e-08	-0.88	0.04	0.95	FALSE
23	GTEx	Heart Left Ventricle	CRAT	0.18	0.13	lasso	5	0.14	1.1e-07	5.8	-6.1	1.0e-09	-0.90	0.04	0.96	FALSE
24	GTEx	Heart Left Ventricle	RP11-247A12.1	0.14	0.11	lasso	5	0.13	1.7e-07	5.8	-5.6	1.9e-08	-0.82	0.04	0.95	FALSE
25	GTEx	Lung	CRAT	0.19	0.16	enet	17	0.17	6.7e-13	5.6	-5.8	5.0e-09	-0.88	0.06	0.94	FALSE
26	GTEx	Lung	PPP2R4	0.07	0.03	lasso	3	0.03	3.8e-03	5.6	-5.8	6.7e-09	-0.91	0.04	0.95	FALSE
27	GTEx	Muscle Skeletal	CRAT	0.13	0.14	lasso	4	0.13	8.3e-13	5.7	-5.7	1.0e-08	-0.89	0.05	0.95	FALSE
28	GTEx	Muscle Skeletal	RP11-247A12.1	0.08	0.10	lasso	2	0.09	1.9e-09	5.7	-5.7	1.0e-08	-0.89	0.05	0.95	FALSE
29	GTEx	Nerve Tibial	CRAT	0.14	0.07	lasso	3	0.05	2.6e-04	5.6	-5.7	1.6e-08	-0.80	0.04	0.94	FALSE
30	GTEx	Pancreas	CRAT	0.31	0.40	lasso	6	0.43	8.0e-20	5.8	5.9	4.4e-09	0.87	0.04	0.96	FALSE
31	GTEx	Pancreas	DOLPP1	0.14	0.14	lasso	3	0.08	2.7e-04	5.6	5.6	2.8e-08	0.75	0.03	0.95	FALSE
32	GTEx	Pancreas	RP11-247A12.1	0.27	0.35	lasso	7	0.36	8.4e-16	5.8	5.9	3.1e-09	0.87	0.04	0.96	FALSE
33	GTEx	Skin Sun Exposed Lower leg	PPP2R4	0.08	0.03	lasso	4	0.02	8.1e-03	5.6	-5.8	7.4e-09	-0.83	0.04	0.95	FALSE
34	GTEx	Stomach	CRAT	0.26	0.10	lasso	7	0.08	1.6e-04	5.6	-5.8	4.9e-09	-0.86	0.04	0.94	FALSE
35	GTEx	Thyroid	CRAT	0.12	0.09	lasso	6	0.09	1.3e-07	5.8	-5.9	3.9e-09	-0.92	0.03	0.97	FALSE
36	GTEx	Whole Blood	CRAT	0.07	0.09	lasso	1	0.08	3.4e-08	5.7	-5.7	1.0e-08	-0.88	0.04	0.96	FALSE
37	GTEx	Whole Blood	RP11-247A12.1	0.10	0.03	lasso	6	0.01	1.7e-02	5.8	-5.8	6.1e-09	-0.86	0.04	0.88	FALSE
38	YFS	Blood	CRAT	0.13	0.19	enet	27	0.22	2.6e-71	5.9	-5.9	3.5e-09	-0.85	0.03	0.97	FALSE
39	The Cancer Genome Atlas	Glioblastoma Multiforme	PPP2R4	0.16	0.04	blup	42	0.08	2.3e-03	4.2	-5.4	5.8e-08	-0.83	0.03	0.61	FALSE
40	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	IER5L	0.02	0.03	lasso	2	0.02	1.1e-03	6.1	-6.2	7.2e-10	-0.97	0.01	0.93	TRUE
41	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CRAT	0.03	0.01	blup	32	0.01	8.9e-03	5.6	-5.9	3.1e-09	-0.87	0.02	0.93	FALSE
42	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CRAT	0.06	0.04	enet	6	0.05	6.3e-04	5.8	-5.6	2.8e-08	-0.79	0.02	0.93	FALSE
43	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PPP2R4	0.06	0.05	blup	41	0.08	3.7e-05	5.7	-5.9	3.5e-09	-0.87	0.03	0.94	FALSE
44	The Cancer Genome Atlas	Brain Lower Grade Glioma	CRAT	0.03	0.04	blup	31	0.03	1.6e-04	5.8	-5.8	5.3e-09	-0.88	0.02	0.98	FALSE
45	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	CRAT	0.07	0.08	enet	3	0.10	2.7e-05	5.7	-5.7	9.7e-09	-0.87	0.02	0.97	FALSE
46	The Cancer Genome Atlas	Lung Adenocarcinoma	CRAT	0.07	0.08	lasso	4	0.09	3.0e-10	5.7	-5.8	5.7e-09	-0.85	0.02	0.98	FALSE
47	The Cancer Genome Atlas	Lung Adenocarcinoma	PPP2R4	0.03	0.01	blup	40	0.03	2.9e-04	5.6	-6.0	2.3e-09	-0.88	0.02	0.94	FALSE
48	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CRAT	0.03	0.03	blup	31	0.03	1.6e-04	5.7	-5.5	3.3e-08	-0.88	0.02	0.97	FALSE
49	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	PPP2R4	0.13	0.06	lasso	2	0.06	1.1e-04	5.7	-5.8	8.0e-09	-0.87	0.04	0.90	FALSE
50	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CRAT	0.07	0.05	lasso	1	0.03	2.7e-02	5.6	-5.6	1.6e-08	-0.80	0.01	0.69	FALSE
51	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	PPP2R4	0.07	0.04	blup	45	0.03	1.8e-02	5.8	-6.0	1.6e-09	-0.94	0.01	0.75	FALSE
52	The Cancer Genome Atlas	Prostate Adenocarcinoma	CRAT	0.02	0.02	blup	31	0.02	4.5e-03	5.7	-5.5	2.9e-08	-0.88	0.02	0.86	FALSE
53	The Cancer Genome Atlas	Prostate Adenocarcinoma	PPP2R4	0.03	0.01	blup	43	0.02	1.7e-03	5.7	-5.9	3.9e-09	-0.92	0.03	0.84	FALSE
54	The Cancer Genome Atlas	Soft Tissue Sarcoma	CRAT	0.10	0.06	blup	28	0.07	6.4e-05	5.3	-5.2	2.3e-07	-0.84	0.02	0.96	FALSE
55	The Cancer Genome Atlas	Soft Tissue Sarcoma	PPP2R4	0.13	0.11	blup	40	0.10	1.1e-06	5.7	-5.1	3.0e-07	-0.83	0.06	0.94	FALSE
56	The Cancer Genome Atlas	Stomach Adenocarcinoma	CRAT	0.07	0.06	blup	29	0.08	3.1e-06	5.6	-5.7	1.5e-08	-0.86	0.02	0.98	FALSE
57	The Cancer Genome Atlas	Stomach Adenocarcinoma	PPP2R4	0.09	0.10	blup	40	0.09	7.2e-07	5.6	-5.8	5.0e-09	-0.88	0.04	0.96	FALSE
58	The Cancer Genome Atlas	Thyroid Carcinoma	CRAT	0.06	0.11	enet	10	0.11	7.1e-11	5.7	-5.7	9.8e-09	-0.86	0.02	0.98	FALSE