[Hub]/) : Traits : Intelligence (Savage-Jansen 2018) : ← →

chr10:64,195,778-66,034,105

Best TWAS P=2.33e-11 · Best GWAS P=2.88e-10 conditioned to 0.288

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	REEP3	0.05	0.05	lasso	3	0.04	5.9e-06	5.4	5.4	5.9e-08	0.71	0.23	0.77	FALSE
2	GTEx	Brain Frontal Cortex BA9	NRBF2	0.25	0.17	lasso	6	0.16	6.1e-05	5.2	-5.3	1.4e-07	-0.71	0.13	0.77	FALSE
3	GTEx	Esophagus Muscularis	NRBF2	0.10	0.03	enet	22	0.03	3.8e-03	6.3	-5.2	2.2e-07	-0.77	0.01	0.97	FALSE
4	GTEx	Nerve Tibial	NRBF2	0.08	0.09	enet	11	0.06	5.0e-05	5.2	-5.3	1.4e-07	-0.71	0.19	0.80	FALSE
5	GTEx	Testis	NRBF2	0.14	0.08	lasso	12	0.09	6.7e-05	5.2	-5.3	1.3e-07	-0.75	0.08	0.90	FALSE
6	GTEx	Testis	JMJD1C-AS1	0.22	0.08	enet	23	0.10	3.7e-05	-4.7	-5.2	1.6e-07	-0.33	0.63	0.10	FALSE
7	ROSMAP	Brain Pre-frontal Cortex	NRBF2	0.34	0.46	lasso	5	0.46	3.1e-66	5.2	-5.2	2.0e-07	-0.71	0.21	0.79	FALSE
8	The Cancer Genome Atlas	Breast Invasive Carcinoma	NRBF2	0.05	0.06	lasso	2	0.06	5.5e-12	5.2	-5.3	9.1e-08	-0.74	0.25	0.75	FALSE
9	The Cancer Genome Atlas	Glioblastoma Multiforme	JMJD1C	0.11	0.02	blup	87	0.05	1.4e-02	5.4	-5.9	3.1e-09	-0.68	0.03	0.40	FALSE
10	The Cancer Genome Atlas	Glioblastoma Multiforme	NRBF2	0.17	0.09	enet	10	0.13	1.1e-04	5.2	-5.5	3.1e-08	-0.67	0.05	0.57	FALSE
11	The Cancer Genome Atlas	Brain Lower Grade Glioma	NRBF2	0.08	0.08	enet	6	0.08	4.3e-09	5.2	-5.3	1.1e-07	-0.78	0.15	0.85	FALSE
12	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	LOC84989	0.10	0.05	blup	19	0.04	7.7e-03	-4.8	-5.3	1.5e-07	-0.52	0.01	0.39	FALSE
13	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	NRBF2	0.18	0.13	enet	11	0.08	2.5e-04	5.4	-5.8	5.7e-09	-0.82	0.01	0.96	FALSE
14	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	NRBF2	0.08	0.02	blup	40	0.04	8.6e-03	5.2	-5.3	9.8e-08	-0.63	0.02	0.24	FALSE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	NRBF2	0.08	0.09	lasso	6	0.08	9.7e-09	5.4	-5.2	1.9e-07	-0.72	0.20	0.80	FALSE
16	The Cancer Genome Atlas	Thyroid Carcinoma	NRBF2	0.14	0.10	enet	16	0.09	8.1e-09	5.4	-6.7	2.3e-11	-0.86	0.03	0.97	TRUE