Best TWAS P=6.95e-08 · Best GWAS P=2.23e-07 conditioned to 0.0175
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Vagina | MED19 | 0.26 | 0.03 | lasso | 10 | 0.06 | 1.5e-02 | 4.0 | 5.4 | 6.9e-08 | -0.61 | 0.06 | 0.39 | TRUE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | SERPING1 | 0.06 | 0.03 | blup | 52 | 0.04 | 6.3e-05 | -4.8 | 5.3 | 1.4e-07 | -0.87 | 0.01 | 0.98 | FALSE |