Best TWAS P=2.33e-07 · Best GWAS P=3.93e-08 conditioned to 0.0221
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | SAE1 | 0.12 | 0.04 | lasso | 5 | 0.07 | 1.7e-10 | -3.6 | -5.2 | 2.3e-07 | 0.36 | 0.13 | 0.85 | TRUE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | GRLF1 | 0.07 | 0.01 | blup | 51 | 0.03 | 4.3e-04 | -2.7 | -5.2 | 2.5e-07 | 0.31 | 0.04 | 0.12 | TRUE |