Best TWAS P=7.97e-09 · Best GWAS P=1e-09 conditioned to NaN
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | DDX56 | 0.07 | 0.01 | lasso | 4 | 0.01 | 4.8e-02 | -5.0 | 5.5 | 5.0e-08 | 0.38 | 0.02 | 0.94 | FALSE |
| 2 | METSIM | Adipose | NPC1L1 | 0.11 | 0.12 | bslmm | 357 | 0.14 | 5.0e-20 | 6.1 | 5.8 | 8.0e-09 | 0.75 | 0.00 | 1.00 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | DDX56 | 0.05 | 0.03 | lasso | 8 | 0.03 | 9.3e-05 | 4.3 | 5.6 | 1.7e-08 | 0.34 | 0.22 | 0.21 | FALSE |
| 4 | YFS | Blood | TMED4 | 0.13 | 0.12 | lasso | 13 | 0.15 | 1.3e-45 | -5.3 | 5.4 | 8.2e-08 | 0.53 | 0.02 | 0.98 | TRUE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | DDX56 | 0.02 | 0.02 | enet | 5 | 0.01 | 2.5e-02 | -5.0 | 5.3 | 1.1e-07 | 0.27 | 0.03 | 0.79 | TRUE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DDX56 | 0.03 | 0.02 | blup | 44 | 0.02 | 2.0e-03 | -5.0 | 5.3 | 9.4e-08 | 0.25 | 0.04 | 0.92 | TRUE |