[Hub]/) : Traits : LDL Cholesterol :

chr9:135,629,944-137,034,272

Best TWAS P=6.2e-30 · Best GWAS P=2.34e-21 conditioned to 0.00206

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial CACFD1 0.10 0.03 lasso 4 0.03 1.7e-03 -1.5 5.5 3.9e-08 0.41 0.13 0.37 FALSE
2 GTEx Testis CACFD1 0.26 0.05 enet 25 0.10 5.3e-05 6.7 5.5 3.1e-08 0.34 0.30 0.15 FALSE
3 The Cancer Genome Atlas Breast Invasive Carcinoma ABO 0.07 0.08 lasso 3 0.08 5.0e-16 7.3 7.1 1.0e-12 0.63 1.00 0.00 FALSE
4 The Cancer Genome Atlas Breast Invasive Carcinoma OBP2B 0.03 0.02 blup 33 0.02 5.5e-05 -5.2 6.6 3.3e-11 0.21 0.23 0.46 FALSE
5 The Cancer Genome Atlas Colon Adenocarcinoma ABO 0.27 0.31 blup 43 0.33 2.1e-19 6.9 5.1 2.7e-07 0.52 1.00 0.00 FALSE
6 The Cancer Genome Atlas Esophageal Carcinoma ABO 0.27 0.13 lasso 2 0.11 1.8e-04 6.9 6.9 5.3e-12 0.63 0.35 0.03 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ABO 0.20 0.19 blup 43 0.33 3.0e-38 -3.8 5.6 1.7e-08 0.37 1.00 0.00 FALSE
8 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ABO 0.31 0.38 lasso 5 0.42 3.1e-26 8.1 7.7 1.4e-14 0.54 1.00 0.00 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma ABO 0.26 0.23 enet 10 0.26 6.0e-29 7.3 6.4 1.2e-10 0.66 1.00 0.00 FALSE
10 The Cancer Genome Atlas Liver Hepatocellular Carcinoma ABO 0.23 0.23 lasso 2 0.24 2.2e-11 8.1 8.1 8.2e-16 0.53 1.00 0.00 FALSE
11 The Cancer Genome Atlas Lung Adenocarcinoma ABO 0.21 0.25 lasso 5 0.25 2.1e-29 7.3 7.2 5.6e-13 0.59 1.00 0.00 FALSE
12 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ABO 0.08 0.06 blup 43 0.09 1.7e-10 7.3 5.8 7.1e-09 0.40 1.00 0.00 FALSE
13 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma ABO 0.28 0.22 lasso 8 0.22 1.2e-14 7.3 7.5 6.9e-14 0.63 1.00 0.00 FALSE
14 The Cancer Genome Atlas Pancreatic Adenocarcinoma ABO 0.23 0.21 lasso 5 0.20 6.7e-09 8.1 6.0 2.1e-09 0.49 0.99 0.00 FALSE
15 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ABO 0.23 0.23 lasso 3 0.23 2.0e-09 6.9 7.2 5.5e-13 0.61 0.99 0.00 FALSE
16 The Cancer Genome Atlas Rectum Adenocarcinoma ABO 0.48 0.23 enet 10 0.27 4.7e-07 8.3 8.2 3.0e-16 0.65 0.18 0.24 FALSE
17 The Cancer Genome Atlas Soft Tissue Sarcoma ABO 0.32 0.18 enet 10 0.20 2.3e-12 7.3 5.2 1.9e-07 0.49 1.00 0.00 FALSE
18 The Cancer Genome Atlas Testicular Germ Cell Tumors ABO 0.41 0.17 enet 12 0.25 3.0e-09 -3.9 5.9 3.6e-09 0.37 0.85 0.02 FALSE
19 The Cancer Genome Atlas Thyroid Carcinoma ABO 0.44 0.57 enet 18 0.60 1.9e-73 7.3 6.5 8.4e-11 0.51 1.00 0.00 FALSE
20 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma ABO 0.23 0.07 blup 44 0.12 4.3e-04 8.1 11.4 6.2e-30 0.62 0.02 0.15 TRUE