[Hub]/) : Traits : LDL Cholesterol : ← →

chr9:135,629,944-137,034,272

Best TWAS P=6.2e-30 · Best GWAS P=2.34e-21 conditioned to 0.00206

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Tibial	CACFD1	0.10	0.03	lasso	4	0.03	1.7e-03	-1.5	5.5	3.9e-08	0.41	0.13	0.37	FALSE
2	GTEx	Testis	CACFD1	0.26	0.05	enet	25	0.10	5.3e-05	6.7	5.5	3.1e-08	0.34	0.30	0.15	FALSE
3	The Cancer Genome Atlas	Breast Invasive Carcinoma	ABO	0.07	0.08	lasso	3	0.08	5.0e-16	7.3	7.1	1.0e-12	0.63	1.00	0.00	FALSE
4	The Cancer Genome Atlas	Breast Invasive Carcinoma	OBP2B	0.03	0.02	blup	33	0.02	5.5e-05	-5.2	6.6	3.3e-11	0.21	0.23	0.46	FALSE
5	The Cancer Genome Atlas	Colon Adenocarcinoma	ABO	0.27	0.31	blup	43	0.33	2.1e-19	6.9	5.1	2.7e-07	0.52	1.00	0.00	FALSE
6	The Cancer Genome Atlas	Esophageal Carcinoma	ABO	0.27	0.13	lasso	2	0.11	1.8e-04	6.9	6.9	5.3e-12	0.63	0.35	0.03	FALSE
7	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ABO	0.20	0.19	blup	43	0.33	3.0e-38	-3.8	5.6	1.7e-08	0.37	1.00	0.00	FALSE
8	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ABO	0.31	0.38	lasso	5	0.42	3.1e-26	8.1	7.7	1.4e-14	0.54	1.00	0.00	FALSE
9	The Cancer Genome Atlas	Brain Lower Grade Glioma	ABO	0.26	0.23	enet	10	0.26	6.0e-29	7.3	6.4	1.2e-10	0.66	1.00	0.00	FALSE
10	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ABO	0.23	0.23	lasso	2	0.24	2.2e-11	8.1	8.1	8.2e-16	0.53	1.00	0.00	FALSE
11	The Cancer Genome Atlas	Lung Adenocarcinoma	ABO	0.21	0.25	lasso	5	0.25	2.1e-29	7.3	7.2	5.6e-13	0.59	1.00	0.00	FALSE
12	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ABO	0.08	0.06	blup	43	0.09	1.7e-10	7.3	5.8	7.1e-09	0.40	1.00	0.00	FALSE
13	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ABO	0.28	0.22	lasso	8	0.22	1.2e-14	7.3	7.5	6.9e-14	0.63	1.00	0.00	FALSE
14	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ABO	0.23	0.21	lasso	5	0.20	6.7e-09	8.1	6.0	2.1e-09	0.49	0.99	0.00	FALSE
15	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ABO	0.23	0.23	lasso	3	0.23	2.0e-09	6.9	7.2	5.5e-13	0.61	0.99	0.00	FALSE
16	The Cancer Genome Atlas	Rectum Adenocarcinoma	ABO	0.48	0.23	enet	10	0.27	4.7e-07	8.3	8.2	3.0e-16	0.65	0.18	0.24	FALSE
17	The Cancer Genome Atlas	Soft Tissue Sarcoma	ABO	0.32	0.18	enet	10	0.20	2.3e-12	7.3	5.2	1.9e-07	0.49	1.00	0.00	FALSE
18	The Cancer Genome Atlas	Testicular Germ Cell Tumors	ABO	0.41	0.17	enet	12	0.25	3.0e-09	-3.9	5.9	3.6e-09	0.37	0.85	0.02	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	ABO	0.44	0.57	enet	18	0.60	1.9e-73	7.3	6.5	8.4e-11	0.51	1.00	0.00	FALSE
20	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	ABO	0.23	0.07	blup	44	0.12	4.3e-04	8.1	11.4	6.2e-30	0.62	0.02	0.15	TRUE