Best TWAS P=4.9e-08 · Best GWAS P=1.51e-07 conditioned to 0.245
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | EVI5 | 0.03 | 0.01 | blup | 335 | 0.02 | 1.3e-03 | -5.1 | -5.2 | 1.7e-07 | 0.92 | 0.03 | 0.93 | FALSE |
| 2 | GTEx | Artery Tibial | EVI5 | 0.08 | 0.08 | lasso | 10 | 0.12 | 9.5e-10 | -5.1 | -5.4 | 6.7e-08 | 0.88 | 0.04 | 0.96 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | EVI5 | 0.18 | 0.11 | enet | 28 | 0.20 | 5.9e-15 | -4.3 | -5.3 | 9.9e-08 | 0.83 | 0.18 | 0.81 | FALSE |
| 4 | GTEx | Heart Atrial Appendage | EVI5 | 0.09 | 0.06 | lasso | 7 | 0.05 | 4.2e-03 | -5.1 | -5.2 | 2.6e-07 | 1.00 | 0.03 | 0.92 | FALSE |
| 5 | GTEx | Whole Blood | EVI5 | 0.03 | 0.01 | lasso | 2 | 0.01 | 6.8e-02 | -5.2 | -5.3 | 1.3e-07 | 0.96 | 0.04 | 0.94 | FALSE |
| 6 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | EVI5 | 0.08 | 0.04 | blup | 96 | 0.06 | 8.6e-08 | -4.0 | -5.3 | 1.0e-07 | 0.88 | 0.04 | 0.96 | FALSE |
| 7 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | EVI5 | 0.04 | 0.02 | blup | 96 | 0.04 | 1.4e-03 | -4.5 | -5.5 | 4.9e-08 | 0.85 | 0.03 | 0.63 | TRUE |
| 8 | The Cancer Genome Atlas | Prostate Adenocarcinoma | EVI5 | 0.06 | 0.10 | blup | 94 | 0.10 | 1.7e-10 | -5.2 | -5.4 | 6.8e-08 | 0.92 | 0.01 | 0.98 | FALSE |