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Lupus
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chr19:9,755,448-11,146,499
Best TWAS P=3e-08 · Best GWAS P=1.54e-12 conditioned to 9.6e-08
9.8M
10M
10.2M
10.4M
10.6M
10.8M
11M
11.2M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
ICAM5
0.03
0.02
blup
48
0.02
4.5e-03
4.8
5.5
3.0e-08
-0.33
0.02
0.78
TRUE
1
GTEx
Brain Frontal Cortex BA9
ICAM3
0.40
0.13
lasso
8
0.22
1.3e-06
4.3
-5.2
2.3e-07
0.26
0.20
0.07
TRUE