Best TWAS P=3e-08 · Best GWAS P=1.54e-12 conditioned to 9.6e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Frontal Cortex BA9 | ICAM3 | 0.40 | 0.13 | lasso | 8 | 0.22 | 1.3e-06 | 4.3 | -5.2 | 2.3e-07 | 0.26 | 0.20 | 0.07 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ICAM5 | 0.03 | 0.02 | blup | 48 | 0.02 | 4.5e-03 | 4.8 | 5.5 | 3.0e-08 | -0.33 | 0.02 | 0.78 | TRUE |