TWAS hub - ICAM3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1750	0.0390	4.5e-08	0.119	0.059	0.106	0.099	0.108	2.6e-14	9.6e-08	6.9e-13	4.8e-12	5.0e-13
2	GTEx	Adipose Subcutaneous	0.1260	0.0440	1.9e-03	0.072	NA	0.041	NA	0.049	1.6e-06	NA	2.5e-04	NA	6.9e-05
3	GTEx	Brain Caudate basal ganglia	0.5560	0.0980	7.6e-06	0.340	NA	0.271	NA	0.333	1.5e-10	NA	2.0e-08	NA	2.5e-10
4	GTEx	Brain Cortex	0.3610	0.1170	4.7e-03	0.260	NA	0.329	NA	0.339	7.7e-08	NA	7.2e-10	NA	3.7e-10
5	GTEx	Brain Frontal Cortex BA9	0.3969	0.0933	1.8e-04	0.134	NA	0.090	NA	0.224	2.1e-04	NA	2.3e-03	NA	1.3e-06
6	GTEx	Brain Hippocampus	0.4943	0.1090	2.7e-04	0.188	NA	0.016	NA	0.078	3.5e-05	NA	1.3e-01	NA	6.9e-03
7	GTEx	Heart Left Ventricle	0.3162	0.0734	3.6e-05	0.170	NA	0.113	NA	0.187	2.1e-09	NA	1.3e-06	NA	3.0e-10
8	ROSMAP	Brain Pre-frontal Cortex	0.2855	0.0406	0.0e+00	0.270	0.204	0.251	0.258	0.265	1.0e-34	9.9e-26	4.7e-32	4.8e-33	5.9e-34
9	YFS	Blood	0.0816	0.0214	2.4e-10	0.062	0.034	0.053	0.061	0.058	1.2e-19	2.3e-11	8.8e-17	4.4e-19	2.2e-18
10	TCGA	Brain Lower Grade Glioma	0.0758	0.0292	6.9e-06	0.068	0.061	0.065	NA	0.066	3.2e-08	1.9e-07	6.9e-08	NA	5.8e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Lupus	9.7	14.6	26.7	-4.2	-3.7	-4.0	-4.8	-5.2	-0.0	-1.5	-4.3	3.0	-4.4
Primary Biliary Cirrhosis	8.5	12.1	20.2	-4.3	-3.9	-3.6	-4.1	-4.1	-0.8	-1.1	-4.4	0.6	-4.5
Medication: Lisinopril	7.7	9.9	15.1	3.1	3.9	3.1	3.4	3.0	2.9	3.6	3.2	0.9	3.4
Rheumatoid Arthritis	7.2	10.0	18.7	-3.5	-3.1	-3.5	-3.9	-4.3	-0.1	-0.7	-3.6	2.0	-3.7
Heart disease (siblings)	7.2	8.8	13.6	2.7	3.3	2.3	3.4	3.6	3.0	3.7	2.8	0.6	2.9
Medication: Atenolol	4.8	6.1	11.8	2.1	2.8	2.6	3.3	3.4	2.1	2.3	2.0	-0.2	2.3
Tinnitus: Yes, now most or all of the time	4.6	5.4	9.0	3.0	2.5	2.9	1.0	1.7	-1.0	0.1	3.0	2.9	2.8
Breast cancer (self-reported)	4.3	5.1	8.8	2.7	2.9	1.9	2.1	2.6	0.6	1.8	2.9	0.1	3.0
Ever had stillbirth, spontaneous miscarriage or termination	4.1	4.4	10.7	-1.8	-2.1	-1.6	-2.0	-1.5	-3.3	-3.0	-1.8	-0.7	-1.9
Osteoporosis (self-reported)	4.1	5.0	8.3	2.3	2.9	2.2	2.0	1.6	2.7	2.7	2.3	-0.4	2.4
Medication: Bendroflumethiazide	4.1	6.2	10.3	2.9	3.2	2.8	2.1	2.3	1.5	2.4	3.0	0.9	3.0
Medication: Blood pressure	4.0	7.5	12.6	3.4	3.5	3.0	2.0	2.8	0.7	2.2	3.5	-0.2	3.5
Respiratory disease	3.9	8.8	16.7	-3.1	-2.9	-3.3	-3.8	-4.1	-1.7	-2.1	-3.2	0.4	-3.2
Allergy or Eczema	3.7	9.8	22.0	-3.4	-3.2	-2.8	-4.0	-4.7	-0.4	-1.3	-3.5	1.7	-3.7
Medication for cholesterol	3.6	5.4	9.3	-2.9	-3.0	-2.6	-1.5	-2.7	-0.5	-1.5	-2.8	1.6	-2.7
Asthma	3.4	6.7	13.8	-2.5	-2.2	-2.6	-3.6	-3.7	-2.2	-1.9	-2.5	0.9	-2.6
Ever taken oral contraceptive pill	3.4	3.8	7.3	2.0	2.2	1.8	1.7	2.7	0.8	0.8	2.3	1.8	2.3
Mother’s age at death	3.4	4.3	6.3	-2.0	-2.4	-2.2	-2.4	-2.5	-1.8	-2.3	-1.8	-0.0	-1.9
Hayfever, allergic rhinitis or eczema	3.3	7.1	16.8	-2.7	-2.5	-2.2	-3.6	-4.1	-0.4	-1.4	-2.8	2.1	-2.9
Heart attack/myocardial infarction (self-reported)	3.1	4.0	5.7	2.1	2.4	1.9	2.0	2.2	2.0	1.9	2.0	1.0	2.1
Medication: Co-codamol	2.9	3.4	5.9	1.8	1.8	1.5	2.4	2.4	1.4	1.6	1.9	-1.3	2.0
Exposure to tobacco smoke at home	2.9	3.3	6.4	1.9	1.5	1.9	2.5	2.4	1.2	1.3	1.9	0.3	2.0
Illness, injury, bereavement, stress in last 2 years	2.9	3.5	10.2	1.5	1.8	1.6	2.0	2.0	3.2	2.1	1.4	-0.3	1.5
Asthma (self-reported)	2.9	5.8	13.3	-2.3	-2.0	-2.5	-3.4	-3.7	-1.7	-1.4	-2.3	1.2	-2.5
Blood White Count	2.8	20.6	45.2	4.5	4.4	4.0	5.2	6.7	0.9	3.9	4.6	-3.9	4.9
Allergy	2.8	6.4	14.3	2.6	2.3	2.5	3.4	3.8	0.4	0.7	2.7	-1.8	2.8
Headache pain in last month	2.8	4.8	7.1	-2.5	-2.5	-2.1	-2.0	-2.4	-1.5	-1.6	-2.7	1.4	-2.6
High blood pressure	2.7	7.5	9.9	2.9	3.1	2.7	2.8	3.0	2.1	3.2	3.0	-0.6	3.0
Heart attack	2.7	3.5	5.0	2.0	2.2	1.8	1.8	2.1	1.7	1.7	1.9	1.2	2.0
Vascular/heart problems diagnosed by doctor	2.7	7.3	10.1	-2.9	-3.2	-2.9	-2.8	-3.0	-2.0	-3.0	-2.9	-0.3	-3.0
Hypertension (Self-reported)	2.6	7.3	10.5	2.9	3.2	2.8	2.7	3.0	1.7	3.0	3.0	-0.5	3.0
High cholesterol (Self-reported)	2.6	4.7	15.7	1.1	1.7	1.5	3.2	4.0	2.4	2.0	1.1	-0.9	1.5
Eye problems/disorders: Diabetes related eye disease	2.5	2.8	5.3	-2.1	-2.1	-2.3	-1.0	-1.6	-0.0	-0.3	-1.9	-1.7	-1.9
Depression (self-reported)	2.5	3.0	5.7	-1.2	-1.9	-1.0	-2.3	-2.4	-2.0	-2.0	-1.2	1.2	-1.4
Illnesses of siblings: Diabetes	2.5	3.1	6.2	1.4	1.7	1.2	2.5	2.4	1.5	1.8	1.8	0.4	2.0
Fractured/broken bones in last 5 years	2.4	3.1	6.8	2.5	2.0	2.0	1.0	1.3	0.2	0.7	2.6	0.2	2.4
Father’s age at death	2.3	3.1	5.5	-1.6	-1.7	-1.3	-2.1	-2.3	-1.9	-2.2	-1.5	0.2	-1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.3	2.6	6.4	2.0	1.4	1.9	0.1	1.2	-1.2	-0.7	2.0	2.5	1.8
Serious illness, injury or assault to yourself	2.2	2.7	4.1	-2.0	-1.8	-2.0	-0.9	-0.9	-1.2	-1.1	-2.0	-1.9	-1.8
Blood clot in the leg (DVT)	2.2	2.9	5.2	-2.2	-2.2	-1.9	-1.3	-0.8	-0.8	-1.1	-2.3	-1.0	-2.2
Relative age voice broke	2.1	3.2	5.4	1.7	2.3	1.4	2.3	2.2	1.5	1.0	1.8	0.9	1.9
Diastolic blood pressure, automated reading	2.1	6.4	8.3	2.6	2.9	2.7	2.6	2.4	2.7	2.8	2.5	-0.8	2.6
Neuroticism	2.0	4.8	12.0	-1.6	-1.8	-1.5	-3.3	-3.5	-2.1	-1.9	-1.6	1.5	-1.9
Hair/balding pattern: Pattern 2	2.0	2.6	11.0	-0.7	-0.9	-1.0	-2.1	-1.2	-3.3	-2.2	-0.6	0.8	-0.9
Birth weight of first child	2.0	3.7	7.2	-2.3	-1.8	-1.2	-1.2	-1.1	-1.9	-2.7	-2.4	-1.7	-2.2
Frequency of depressed mood in last 2 weeks	1.9	2.7	6.4	-0.9	-1.4	-0.9	-2.5	-2.1	-2.2	-1.9	-0.9	1.3	-1.1
Taking other prescription medications	1.9	2.9	6.9	-1.2	-1.2	-0.9	-2.6	-2.6	-0.9	-1.1	-1.3	2.6	-1.3
Illnesses of siblings	1.9	2.6	4.6	-1.5	-2.1	-1.5	-1.4	-1.8	-1.5	-1.8	-1.8	0.4	-1.7
Serious illness, injury or assault of a close relative in last 2 years	1.9	2.2	4.2	-1.3	-1.5	-1.3	-1.2	-1.4	-2.1	-1.7	-1.2	-1.9	-1.2
Deep venous thrombosis (DVT) (self-reported)	1.9	2.5	4.5	-2.1	-2.1	-1.8	-1.1	-0.6	-0.7	-1.0	-2.1	-1.2	-2.0
Alzheimer’s Disease (including proxy)	1.8	2.6	3.8	-1.9	-1.9	-1.7	-1.6	-1.4	-1.1	-1.5	-1.9	-0.3	-1.9
Ovarian Cancer	1.8	2.4	3.5	-1.4	-1.7	-1.9	-1.7	-1.2	-1.8	-1.7	-1.4	1.1	-1.4
Fluid intelligence score	1.8	3.7	7.1	-1.7	-1.9	-1.2	-2.7	-2.5	-1.5	-2.3	-1.8	-1.3	-2.0
Type 2 Diabetes (T2D) (2012)	1.7	1.9	3.5	1.7	1.8	1.4	0.5	1.5	-0.9	0.4	1.9	1.0	1.8
Smoking status: Previous	1.7	2.5	3.2	1.6	1.8	1.6	1.6	1.6	0.8	1.8	1.8	-1.4	1.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.7	1.9	2.9	-1.7	-1.7	-1.7	-0.6	-1.1	-1.1	-1.5	-1.6	-1.1	-1.4
Cholesterol lowering medication	1.7	2.5	6.7	1.6	1.7	1.8	1.5	2.6	0.9	0.9	1.4	-1.5	1.4
Depression (Nagel 2018)	1.6	2.3	6.9	-0.2	-0.8	-0.2	-2.4	-2.0	-1.8	-1.5	-0.1	2.6	-0.4
Medication: Omeprazole (e.g. Zanprol)	1.6	1.9	4.4	1.8	1.7	2.1	0.6	0.5	0.7	1.0	1.7	1.4	1.5
Townsend deprivation index at recruitment	1.5	2.1	3.2	1.7	1.7	1.5	1.4	1.3	0.7	1.8	1.7	0.5	1.7
Diverticular disease/diverticulitis (self-reported)	1.5	1.8	4.7	1.9	1.4	1.6	0.1	0.1	0.1	0.4	2.2	1.0	1.9
Heel bone mineral density (BMD) T-score, automated (right)	1.5	3.4	6.1	-2.4	-2.2	-1.7	-1.6	-2.1	0.6	-0.3	-2.4	-1.2	-2.5
Hayfever/allergic rhinitis (self-reported)	1.5	2.0	5.9	-1.3	-1.4	-1.6	-1.8	-2.4	0.3	-0.5	-1.2	0.9	-1.4
Wheeze or whistling in the chest in last year	1.5	2.6	5.6	-1.4	-1.5	-1.5	-1.8	-2.4	-1.8	-1.4	-1.6	0.2	-1.6
Age at first live birth	1.5	2.6	4.9	-2.2	-1.9	-2.1	-0.8	-1.4	-0.2	-0.8	-2.2	-1.0	-2.0
Medication: Blood pressure	1.5	2.7	6.0	1.0	1.4	1.5	2.2	1.7	2.4	2.3	0.9	0.5	1.2
Cardiovascular Disease	1.4	4.5	7.0	2.0	2.3	2.2	2.2	2.6	1.6	2.5	2.1	-1.0	2.2
Had other major operations	1.4	1.7	2.8	1.7	1.5	1.3	1.3	1.4	0.2	0.8	1.7	-0.7	1.7
Mouth/teeth dental problems	1.4	2.2	5.0	-2.1	-1.4	-2.2	-0.2	-0.9	1.3	0.9	-1.9	-0.6	-1.7
Medication: Simvastatin	1.4	2.1	4.6	0.9	1.4	1.5	1.7	2.1	2.1	1.8	0.6	-0.5	0.7
Eye problems/disorders: None of the above	1.4	1.6	3.5	1.5	1.5	1.9	1.0	1.4	0.6	0.3	1.6	0.4	1.5
Suffer from ‘nerves’	1.4	2.3	4.9	2.1	1.8	1.8	0.3	0.8	0.0	0.0	2.2	1.1	2.1
Overall health rating	1.4	3.1	4.9	2.2	2.1	2.0	1.6	1.7	0.6	1.5	2.2	-0.6	2.2
Family relationship satisfaction	1.4	1.7	3.8	-1.0	-1.2	-0.9	-1.4	-1.4	-2.0	-1.6	-1.1	-1.1	-1.2
Medication: Aspirin	1.4	1.9	3.7	1.4	1.3	1.9	1.5	1.4	0.6	1.2	1.2	1.6	1.2
Crohns Disease (2012)	1.3	2.1	16.5	0.2	-0.3	0.3	-0.6	-0.3	-1.4	-1.3	0.2	4.1	0.1
BMI	1.3	7.6	15.8	2.6	2.9	2.6	4.0	4.0	1.3	1.7	2.6	-1.5	2.8
Heel bone mineral density (BMD) T-score, automated (left)	1.3	3.0	5.4	-2.2	-2.0	-1.5	-1.7	-2.1	0.2	-0.8	-2.2	-0.6	-2.3
Mouth/teeth dental problems: Loose teeth	1.3	1.5	3.8	1.5	1.4	1.4	0.7	1.0	-0.4	0.1	1.4	-1.9	1.2
Medication: Omeprazole	1.3	1.6	2.7	1.4	1.5	1.6	0.8	0.7	1.4	1.5	1.4	0.7	1.3
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.5	7.0	-0.6	-1.2	-1.1	-1.1	-0.6	-2.6	-1.3	-0.4	-1.1	-0.5
Medication: Atorvastatin	1.3	1.6	4.9	1.2	1.5	1.3	1.1	2.2	0.6	0.8	1.2	0.2	1.4
Irritability	1.3	2.2	4.7	-1.1	-1.2	-0.6	-2.2	-1.6	-2.0	-1.9	-1.2	-1.1	-1.2
Bipolar Disorder or Schizophrenia	1.2	3.0	4.6	2.1	2.0	2.0	1.3	1.8	1.1	1.3	2.1	0.6	2.1
Chronotype (morning person)	1.2	2.8	8.5	0.9	1.4	0.8	2.0	1.8	2.5	2.9	1.1	0.0	1.3
Medication: Paracetamol	1.2	2.0	4.1	-1.1	-1.5	-0.4	-1.7	-1.4	-1.9	-2.0	-1.2	-0.9	-1.4
Age at last live birth	1.2	1.7	3.8	-1.9	-1.7	-1.4	-0.5	-1.1	-0.3	-0.6	-1.9	-0.1	-1.7
Commuting to job workplace: Cycle	1.2	1.4	3.5	0.9	0.8	1.4	1.4	0.7	1.9	1.7	0.9	0.5	1.0
Heel T-Score	1.1	8.6	17.4	-3.2	-3.3	-1.8	-3.8	-4.2	-1.8	-2.2	-3.2	0.9	-3.5
Waist Hip Ratio (WHR)	1.1	5.0	8.6	2.5	2.4	2.1	1.4	1.8	1.8	2.9	2.4	2.1	2.3
Lung FEV1/FVC ratio	1.1	5.8	15.2	2.6	2.5	2.5	2.5	3.9	-1.6	-1.4	2.5	-0.4	2.6
Ever used hormone-replacement therapy (HRT)	1.1	1.4	11.5	0.3	0.6	0.5	0.1	0.4	0.8	0.9	0.2	3.4	0.2
Past tobacco smoking	1.1	1.9	3.3	-1.7	-1.6	-1.8	-1.1	-1.2	-0.2	-1.2	-1.8	0.3	-1.7
Medication: Lansoprazole	1.1	1.3	5.7	0.8	0.7	0.8	0.8	1.3	-1.1	-0.3	0.8	2.4	0.9
Hypothyroidism/myxoedema (self-reported)	1.1	2.1	4.4	-1.3	-1.1	-0.8	-1.1	-2.1	1.4	1.7	-1.4	1.8	-1.5
Leg pain on walking	1.1	1.3	3.9	0.1	-0.0	0.6	1.4	0.8	2.0	1.6	-0.2	-1.9	-0.0
Supplements: Fish oil (including cod liver oil)	1.1	1.4	4.2	-0.7	-0.9	-0.1	-2.1	-1.7	-1.4	-1.1	-0.6	1.1	-0.9
Hypothyroidism (self reported)	1.0	2.3	7.0	-0.8	-0.7	-0.3	-0.8	-1.9	1.9	2.3	-1.0	2.6	-1.1
Lung cancer (father)	1.0	1.2	1.7	0.9	1.1	0.9	1.2	1.2	1.1	1.3	0.7	-1.3	0.8
Impedance of arm (left)	1.0	4.5	8.4	-2.0	-2.1	-2.4	-2.7	-2.9	-1.0	-2.2	-1.8	1.4	-2.0
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	2.6	1.5	1.4	1.6	0.5	1.6	0.5	-0.2	1.2	-0.7	1.2
Medication: Allopurinol	1.0	1.3	2.3	-1.4	-0.9	-1.5	-0.5	-0.9	1.1	0.2	-1.4	-1.2	-1.4
Medication: Aspirin	1.0	1.3	3.1	1.1	1.0	1.8	1.3	1.2	0.1	0.9	1.0	1.3	1.0
Hearing aid user	1.0	1.1	2.3	1.3	0.9	1.1	0.4	0.7	0.5	1.0	1.3	1.5	1.2
Commuting to job workplace: Public transport	1.0	1.2	2.9	-0.1	-0.3	0.2	-1.4	-1.7	-1.5	-1.7	-0.1	1.2	-0.4
Illnesses of father: High blood pressure	1.0	1.2	3.1	0.6	1.1	0.4	1.6	1.3	1.6	1.7	0.5	0.1	0.7
Bipolar Disorder (2018)	0.9	1.4	2.6	1.5	1.2	1.2	0.7	1.0	0.0	1.1	1.6	1.2	1.6
Verbal and Numeric Reasoning (VNR)	0.9	2.2	4.6	-1.2	-1.3	-1.1	-2.1	-2.1	-1.1	-1.8	-1.1	-0.9	-1.4
Systolic blood pressure, automated reading	0.9	2.7	5.7	1.4	1.5	1.2	1.6	1.6	2.0	2.4	1.2	-1.9	1.3
Fed-up feelings	0.9	1.6	7.0	0.6	0.1	0.5	-1.4	-1.1	-2.6	-1.5	0.6	1.6	0.3
Age when periods started (menarche)	0.9	2.2	4.3	1.7	1.6	1.2	1.3	1.4	2.1	0.4	1.7	-0.9	1.8
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	2.2	-1.5	-0.9	-1.4	-0.4	-0.7	0.1	-0.5	-1.5	0.0	-1.3
Hearing difficulty/problems with background noise	0.9	1.4	4.7	-0.7	-1.5	-0.4	-0.4	-1.1	-1.9	-2.2	-0.7	0.6	-0.6
Qualifications: None of the above	0.9	2.0	3.1	1.1	1.4	1.1	1.6	1.6	1.8	1.3	1.1	1.7	1.3
Hair/balding pattern: Pattern 3	0.9	1.4	3.0	-1.6	-1.3	-1.1	-0.3	-0.8	0.7	-0.1	-1.7	-1.4	-1.5
Happiness	0.9	1.1	2.0	-1.1	-1.0	-1.1	-1.4	-1.4	-0.6	-0.9	-1.1	-0.3	-1.2
Qualifications: A levels/AS levels or equivalent	0.9	2.1	4.0	-1.5	-1.5	-1.5	-1.4	-2.0	-1.0	-0.7	-1.3	-1.6	-1.5
Leg fat percentage (right)	0.9	3.1	7.6	1.8	1.6	1.5	2.4	2.8	0.4	0.8	1.7	-1.6	1.9
Migraine (self-reported)	0.9	1.1	5.7	-0.4	-0.7	-0.7	-1.0	-0.9	-1.0	-1.0	-0.3	2.4	-0.4
Wears glasses or contact lenses	0.9	1.0	2.1	-1.1	-1.4	-0.8	-0.6	-0.7	-1.3	-1.2	-1.1	0.0	-1.1
Risk taking	0.9	1.3	2.7	1.6	1.5	1.5	0.3	0.5	0.4	0.6	1.6	0.6	1.3
Pain experienced in last month	0.9	1.5	4.2	0.3	0.7	0.1	1.9	1.9	2.1	1.3	0.4	-0.6	0.6
Schizophrenia (2018)	0.8	1.7	2.6	1.5	1.6	1.6	1.1	1.6	1.3	0.7	1.4	-0.2	1.4
Worry (Nagel 2018)	0.8	1.7	7.3	-0.2	-0.4	-0.1	-2.0	-2.0	-0.8	-0.7	-0.2	2.7	-0.4
HbA1C	0.8	0.9	2.0	-0.4	-0.8	-0.4	-1.4	-1.1	-1.2	-1.2	-0.4	1.1	-0.6
Hand grip strength (left)	0.8	2.2	4.9	1.3	1.6	0.7	1.4	1.3	1.9	2.2	1.4	1.1	1.4
Medication: Metformin	0.8	1.2	4.2	0.7	0.5	0.1	1.3	1.1	1.7	2.0	0.8	-0.1	0.9
Severe depression (siblings)	0.8	0.9	1.6	-0.8	-1.1	-0.7	-1.2	-0.9	-1.2	-1.3	-0.8	0.2	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.0	2.6	0.2	-0.4	0.1	-1.5	-1.2	-1.6	-1.4	0.3	1.3	0.1
Multivitamins +/- minerals	0.8	1.0	4.5	0.6	0.1	0.9	-0.7	-0.2	-2.1	-1.8	0.5	0.2	0.2
Supplements: Glucosamine	0.8	1.0	3.2	-0.6	-0.8	-0.7	-1.7	-1.8	-0.8	-0.9	-0.5	-0.1	-0.7
Body mass index (BMI)	0.8	3.5	7.1	1.8	1.9	2.0	2.6	2.7	0.9	1.5	1.6	-1.5	1.8
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	4.0	1.1	0.3	0.9	-0.5	0.0	-2.0	-1.2	1.2	1.2	1.1
Diabetes (self-reported)	0.8	1.2	3.7	0.9	0.8	0.6	1.3	1.1	1.3	1.9	0.9	-0.8	0.9
Neuroticism score	0.8	1.7	4.1	-0.4	-0.7	-0.7	-2.0	-2.0	-1.7	-1.2	-0.4	1.8	-0.6
Impedance of arm (right)	0.8	3.7	6.7	-1.5	-1.7	-2.2	-2.6	-2.6	-1.2	-2.2	-1.3	1.8	-1.5
Noisy workplace	0.8	1.0	3.4	-0.4	-0.9	-0.4	-1.1	-0.7	-1.8	-1.7	-0.4	-0.4	-0.5
Mouth/teeth dental problems: Dentures	0.8	1.4	3.2	1.5	1.2	1.8	0.7	0.7	-0.0	0.2	1.3	1.8	1.2
Medication: Cholesterol lowering	0.8	1.2	3.6	-0.0	0.6	0.4	1.6	1.9	1.8	1.3	-0.2	0.9	0.2
Tense / ‘highly strung’	0.8	1.3	3.0	-0.9	-1.0	-1.1	-1.4	-1.7	-0.9	-0.8	-1.0	1.4	-1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	3.5	0.4	-0.2	0.3	-1.1	-0.6	-1.7	-1.8	0.5	1.9	0.4
Chronic bronchitis/emphysema (mother)	0.8	1.0	5.7	0.8	0.8	0.9	-0.4	-0.5	-0.4	0.0	0.8	2.4	0.8
High blood pressure (siblings)	0.8	1.1	2.3	1.4	1.5	1.3	0.1	0.6	0.6	0.9	1.4	0.6	1.2
Comparative body size at age 10	0.8	2.1	4.1	1.7	1.6	2.0	1.8	1.7	-0.2	0.1	1.5	0.9	1.6
Handedness (chirality/laterality): Left-handed	0.8	1.0	3.2	0.5	0.0	0.9	-0.1	0.5	-1.8	-1.4	0.4	1.8	0.4
Loneliness, isolation	0.8	1.1	5.9	0.2	-0.2	0.5	-0.9	-0.8	-2.4	-1.5	0.2	1.0	0.0
Medication: Gliclazide	0.8	0.9	2.8	0.6	0.7	0.4	1.7	1.4	0.8	0.7	0.6	-1.0	0.7
Medication: Paracetamol	0.8	1.2	2.9	-0.2	-0.7	0.5	-1.4	-0.9	-1.7	-1.6	-0.3	-1.6	-0.6
Depressed Affect (Nagel 2018)	0.7	1.6	7.2	0.6	0.2	0.5	-1.2	-0.9	-2.7	-1.3	0.7	1.7	0.5
Intelligence (Savage-Jansen 2018)	0.7	2.2	6.2	-0.3	-0.8	-0.5	-2.4	-1.8	-2.3	-2.5	-0.1	-0.5	-0.5
Neuroticism (Nagel 2018)	0.7	1.7	4.6	-0.2	-0.5	-0.1	-2.0	-1.9	-1.7	-1.2	-0.1	2.1	-0.4
Schizophrenia (2014)	0.7	1.6	2.8	1.3	1.3	1.3	1.4	1.7	1.4	0.7	1.2	-0.3	1.3
Blood Platelet Count	0.7	8.5	21.1	-3.4	-2.2	-2.9	-3.6	-4.6	1.1	0.2	-3.5	0.1	-3.5
Medication: Levothyroxine sodium	0.7	1.2	5.1	-0.6	-0.2	-0.4	0.2	-0.6	2.2	2.3	-0.7	0.7	-0.6
High blood pressure (mother)	0.7	0.9	3.1	1.2	0.6	0.7	-0.3	-0.0	-1.8	-0.2	1.4	0.8	1.2
Had menopause	0.7	0.9	4.5	0.3	0.8	0.1	0.8	0.2	1.7	2.1	0.4	0.1	0.4
Glaucoma (self-reported)	0.7	0.8	1.8	-0.8	-0.7	-1.3	-1.1	-0.9	-1.1	-1.1	-0.6	-0.5	-0.7
Leg fat mass (right)	0.7	2.6	6.4	1.4	1.5	1.5	2.5	2.3	0.1	0.8	1.3	-1.8	1.5
Number of full sisters	0.7	0.8	2.8	0.5	0.5	0.6	1.2	1.0	1.7	1.4	0.3	-0.1	0.3
Supplements: Vitamin C	0.7	0.9	1.2	1.0	0.8	0.7	0.7	0.9	0.9	1.0	1.1	0.9	1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	4.2	-1.0	-0.8	-1.0	-0.7	-1.7	-1.3	-0.9	-0.9	-2.0	-1.1
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	5.6	0.4	-0.5	0.3	-0.7	-0.3	-2.4	-2.0	0.4	-0.4	0.2
Financial situation satisfaction	0.7	0.9	3.9	0.3	0.1	0.3	1.4	0.9	1.3	0.9	0.1	-2.0	0.2
Ever depressed for a whole week	0.7	0.8	1.5	-0.7	-1.0	-0.9	-1.1	-0.8	-1.2	-1.2	-0.7	0.5	-0.6
Supplements: Calcium	0.7	0.7	5.7	-0.5	-0.3	-0.3	-0.0	-0.3	2.4	0.5	-0.6	0.0	-0.6
Impedance of whole body	0.7	3.4	6.0	-1.7	-2.0	-2.5	-2.2	-2.3	-0.9	-1.9	-1.6	1.1	-1.7
Alzheimer’s Disease (in mother)	0.6	0.7	1.7	-1.2	-0.9	-0.8	0.3	0.3	-0.2	-0.3	-1.1	-1.3	-1.0
HDL Cholesterol	0.6	1.1	2.0	-0.7	-1.1	-0.9	-0.8	-1.4	-1.4	-1.1	-0.6	-1.3	-0.8
Smoking Status	0.6	1.5	3.5	1.5	1.4	1.9	1.0	0.8	0.2	1.0	1.3	1.2	1.2
Average weekly spirits intake	0.6	0.7	1.0	-0.9	-0.8	-0.8	-1.0	-0.7	-1.0	-0.7	-0.9	-0.8	-0.9
Hearing difficulty/problems: Yes	0.6	0.8	3.8	-0.0	-0.6	0.1	-0.2	-0.4	-2.0	-1.9	-0.2	0.4	-0.2
Relative age of first facial hair	0.6	1.3	2.4	1.5	1.5	1.5	0.8	1.0	-0.3	-0.2	1.4	0.9	1.3
Current tobacco smoking	0.6	1.0	3.4	0.0	-0.6	0.3	-1.2	-1.5	-0.9	-1.1	-0.3	1.8	-0.4
Financial difficulties in last 2 years	0.6	0.8	1.6	-0.6	-1.0	-0.5	-0.5	-0.6	-1.2	-1.3	-0.7	-1.1	-0.7
Pain all over the body in last month	0.6	0.6	1.7	1.0	0.7	1.1	-0.2	-0.1	1.3	0.7	0.9	0.4	0.7
Length of working week for main job	0.6	0.7	2.7	0.0	0.4	0.1	0.7	0.3	1.6	1.3	-0.1	-1.3	0.0
Number of full brothers	0.6	0.7	1.2	1.1	0.9	1.1	-0.1	0.7	-0.8	-0.7	1.1	-0.8	0.9
Worry too long after embarrassment	0.6	0.9	2.5	-0.8	-0.8	-1.0	-1.0	-1.5	0.0	0.0	-0.7	1.6	-0.9
Number of children fathered	0.6	0.7	1.2	-1.1	-0.8	-0.8	-0.7	-0.7	-0.5	-0.6	-1.1	-0.4	-1.1
Knee pain experienced in last month	0.6	0.9	3.4	0.3	0.2	0.4	-1.3	-1.0	-1.8	-1.2	0.2	-1.2	0.0
Qualifications: nursing, teaching	0.6	0.9	2.3	-1.0	-1.2	-0.6	-0.4	-1.3	-0.1	-0.3	-1.0	-1.5	-1.1
Eye problems/disorders: Glaucoma	0.6	0.7	1.5	-0.8	-0.7	-1.2	-0.9	-0.5	-1.2	-0.9	-0.7	-0.3	-0.8
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.8	-0.6	-0.7	-0.4	-1.1	-0.8	-0.9	-1.3	-0.7	0.6	-0.6
Crohns Disease (2017)	0.5	1.2	10.5	-0.1	-0.3	0.1	-0.4	-0.4	-0.6	-0.6	-0.1	3.2	-0.1
Coronary Artery Disease (CAD)	0.5	0.6	5.7	-0.3	-0.0	-0.2	0.1	0.6	-0.1	-0.1	-0.4	2.4	0.0
LDL Cholesterol	0.5	0.8	2.5	-0.4	-0.3	-1.0	-0.5	1.2	-1.4	-1.6	-0.3	-0.2	-0.5
Height	0.5	10.2	37.3	-2.6	-1.8	-2.6	-1.6	-3.9	-6.1	-3.2	-2.5	-2.6	-2.7
Type 2 Diabetes (T2D) (2018)	0.5	0.9	2.5	0.5	0.3	0.4	1.6	1.1	1.4	1.5	0.3	-0.4	0.5
Maternal smoking around birth	0.5	0.7	5.2	0.6	0.2	0.8	-0.2	-0.2	0.3	-0.5	0.4	2.3	0.5
Waist circumference	0.5	1.8	3.8	1.2	1.3	1.4	1.9	1.7	0.4	1.0	1.1	-1.7	1.1
Arm fat percentage (right)	0.5	1.8	3.3	1.5	1.4	1.5	1.6	1.8	0.3	0.5	1.4	-1.0	1.5
Prospective memory result	0.5	0.6	2.7	-0.3	-0.2	-0.0	0.2	-0.5	1.4	1.6	-0.4	-0.2	-0.5
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	2.5	-0.9	-1.0	-1.1	-0.3	-1.1	-0.5	-0.4	-0.8	-1.6	-0.8
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	3.6	0.5	-0.1	0.0	-1.2	-0.8	-1.9	-1.2	0.5	-0.9	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	1.4	1.0	0.8	0.9	0.7	1.2	-0.1	0.4	1.1	0.0	1.1
Emphysema/chronic bronchitis	0.5	0.6	3.8	-0.0	-0.2	-0.0	-1.0	-0.6	-0.3	0.4	-0.1	2.0	-0.3
Neck or shoulder pain in last month	0.5	0.7	2.5	0.8	0.4	0.8	-0.5	-0.5	-1.6	-0.5	0.8	1.4	0.5
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.4	-0.9	-0.8	-1.2	0.1	-0.5	0.9	0.7	-0.8	-0.5	-0.6
Eye problems/disorders: Cataract	0.5	0.6	2.2	0.1	0.5	-0.1	0.5	0.1	1.5	1.4	0.0	0.8	0.1
Mineral and other dietary supplements	0.5	0.7	2.5	0.6	0.8	0.4	1.6	1.5	0.3	0.5	0.6	-0.0	0.8
Smoking status: Current	0.5	0.8	2.8	0.4	-0.2	0.6	-0.9	-1.1	-1.0	-1.0	0.1	1.7	0.0
Arm fat mass (left)	0.5	1.9	4.3	1.4	1.5	1.5	2.1	1.7	0.2	0.8	1.2	-1.4	1.3
Miserableness	0.5	0.9	4.8	0.9	0.5	0.6	-0.3	-0.1	-1.0	-0.4	0.9	2.2	0.8
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.1	0.8	0.7	0.6	0.2	0.7	-1.5	-0.2	0.9	0.1	0.9
Leg fat percentage (left)	0.5	1.9	5.0	1.4	1.2	1.1	1.9	2.2	0.2	0.6	1.3	-1.3	1.4
Unable to work because of sickness or disability	0.5	0.6	1.8	1.0	0.8	0.8	0.4	0.4	-0.0	0.4	0.9	1.3	0.8
Alcohol drinker status: Previous	0.5	0.5	1.5	-1.0	-0.7	-0.8	0.4	0.4	0.1	0.2	-0.9	-1.2	-0.7
Breast Cancer	0.4	0.9	7.5	-0.1	0.1	-0.3	0.0	-0.0	1.1	0.8	-0.1	2.7	0.1
Fasting Glucose	0.4	0.5	1.0	0.9	1.0	1.0	0.7	0.4	0.5	0.4	0.8	-0.6	0.6
Ulcerative Colitis	0.4	0.6	3.9	-0.4	-0.4	-0.1	-0.1	0.3	-2.0	-1.2	-0.1	-0.0	-0.1
Average weekly fortified wine intake	0.4	0.5	3.1	-0.5	-0.3	-0.3	-0.6	-0.4	0.1	0.6	-0.4	1.8	-0.3
Worrier / anxious feelings	0.4	0.8	5.7	0.0	-0.0	0.1	-0.9	-1.3	-0.3	-0.3	-0.0	2.4	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	2.2	0.6	0.3	0.6	0.9	0.3	0.6	1.5	0.7	-0.7	0.7
Pulse rate	0.4	0.6	2.2	0.7	0.8	0.5	0.8	1.5	1.0	-0.0	0.6	0.3	0.8
Arm fat mass (right)	0.4	1.5	3.4	1.2	1.3	1.3	1.8	1.7	-0.2	0.5	1.0	-1.2	1.1
Standing height	0.4	4.4	12.1	-1.9	-1.2	-1.7	-1.2	-3.1	-3.5	-1.8	-1.9	-1.3	-2.1
Pulse wave reflection index	0.4	0.5	1.6	0.4	0.2	0.5	-0.7	-0.5	-1.3	-0.8	0.3	-1.0	0.2
Gout (self-reported)	0.4	0.6	0.9	-0.9	-0.9	-0.9	-0.6	-0.9	0.7	-0.1	-0.9	-0.6	-0.9
Medication: Ventolin 100micrograms inhaler	0.4	0.6	3.0	0.0	-0.0	-0.3	-0.4	-0.3	-1.3	-0.8	0.2	1.7	0.2
Shortness of breath walking on level ground	0.4	0.4	0.7	0.6	0.7	0.6	0.5	0.9	0.5	0.8	0.7	-0.7	0.7
Heart disease (mother)	0.4	0.5	1.5	0.2	0.3	0.5	1.1	1.2	0.0	1.2	0.3	-0.4	0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	0.9	-0.6	-0.7	-0.5	-0.8	-0.9	0.9	-0.2	-0.7	-0.7	-0.7
Arm predicted mass (right)	0.4	1.9	5.9	1.0	1.5	1.5	2.4	1.2	-0.4	1.2	0.8	-1.7	0.9
Comparative height size at age 10	0.4	2.4	6.5	-1.7	-1.0	-1.3	-0.9	-2.2	-2.5	-0.8	-1.6	-0.5	-1.7
Illnesses of father: Heart disease	0.4	0.6	2.0	-0.9	-0.8	-1.4	-1.0	-0.2	-0.2	0.2	-0.8	0.3	-0.8
Arm fat percentage (left)	0.4	1.5	2.5	1.3	1.3	1.4	1.6	1.6	0.5	0.5	1.2	-1.2	1.3
Alcohol drinker status: Never	0.4	0.5	2.6	0.0	-0.3	-0.5	-0.5	-1.1	-0.4	-0.1	0.2	1.6	0.0
Ever smoked	0.4	0.8	1.8	1.2	1.0	1.4	0.6	0.4	0.2	0.6	1.1	0.5	1.0
Myopia	0.4	0.5	1.6	0.9	0.8	1.3	-0.1	0.3	0.6	0.9	0.8	-0.1	0.6
Basal cell carcinoma (self-reported)	0.4	0.5	0.9	-0.8	-0.7	-0.4	-0.6	-0.6	-0.9	-0.9	-0.8	0.2	-0.8
Leg fat mass (left)	0.4	1.7	4.6	1.1	1.1	1.1	2.1	1.8	0.0	0.7	1.0	-1.7	1.1
Arm predicted mass (left)	0.4	1.9	4.5	1.2	1.6	1.7	2.1	1.2	-1.1	0.7	1.0	-1.5	1.1
Alzheimer’s Disease (in father)	0.3	0.3	1.3	0.1	-0.2	0.3	-0.7	-0.6	-0.5	-0.5	-0.0	1.1	-0.1
Prostate Cancer	0.3	0.5	1.3	0.6	0.4	0.4	1.1	0.8	0.2	0.5	0.6	-1.1	0.6
Age at First Birth	0.3	0.4	1.9	-0.6	-0.3	-1.4	0.5	-0.2	0.8	0.3	-0.5	-0.7	-0.4
Systolic Blood Pressure	0.3	1.4	6.0	1.0	1.0	0.9	0.4	0.4	1.6	2.4	0.9	-0.7	0.9
Lung FVC	0.3	1.3	1.7	1.2	1.1	1.2	1.0	1.0	1.3	1.3	1.1	-1.1	1.2
Number of treatments/medications taken	0.3	0.5	1.6	0.7	0.6	1.0	-0.7	-0.3	0.4	0.5	0.6	1.3	0.4
Sensitivity / hurt feelings	0.3	0.5	1.3	-0.5	-0.6	-0.7	-0.9	-0.8	-1.1	-0.8	-0.5	-0.5	-0.5
Angina	0.3	0.3	0.7	-0.7	-0.5	-0.5	-0.0	-0.1	0.5	0.9	-0.8	0.7	-0.7
Vitamin and mineral supplements	0.3	0.4	1.3	-0.3	0.0	-0.4	0.5	0.4	1.1	1.1	-0.3	-0.8	-0.1
Hand grip strength (right)	0.3	0.8	2.7	0.5	0.8	0.1	0.9	0.6	1.5	1.6	0.6	-0.3	0.5
Sitting height	0.3	2.0	6.0	-1.1	-0.7	-0.9	-1.2	-2.1	-2.5	-1.3	-1.1	-0.8	-1.3
Number of incorrect matches in round	0.3	0.6	1.7	0.8	0.9	0.6	0.4	0.6	-0.4	0.2	0.8	-1.3	0.8
Forced vital capacity (FVC)	0.3	1.0	3.2	-0.8	-0.8	-0.6	-0.4	-1.0	-1.8	-0.9	-0.7	-1.4	-0.8
Trunk fat-free mass	0.3	2.0	4.7	1.1	1.7	1.7	2.2	1.0	-0.8	1.0	0.9	-2.0	1.0
Hip circumference	0.3	1.2	8.0	0.1	0.5	0.3	1.5	0.9	-0.5	-0.1	-0.0	-2.8	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	0.9	-0.3	-0.5	-0.2	-0.6	-0.2	-0.8	-0.9	-0.3	-1.0	-0.4
Trunk predicted mass	0.3	2.0	4.5	1.1	1.7	1.7	2.1	1.0	-0.9	1.0	1.0	-1.8	1.0
Breastfed as a baby	0.3	0.4	2.1	0.0	0.1	-0.1	0.6	-0.1	0.2	1.2	0.1	-1.4	0.0
Ever highly irritable/argumentative for 2 days	0.3	0.4	2.6	0.7	0.1	0.3	-0.2	-0.3	-0.2	0.1	0.6	1.6	0.5
Medication: Amlodipine	0.3	0.4	1.2	0.8	0.6	0.7	0.2	0.2	0.4	1.1	0.8	-0.1	0.8
Birth weight	0.3	0.7	2.5	0.8	0.5	1.6	-0.8	-0.9	-1.1	-0.6	0.7	0.0	0.4
Arm fat-free mass (right)	0.3	1.6	4.7	0.8	1.3	1.3	2.2	0.9	-0.6	1.1	0.5	-2.0	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	1.0	-0.0	0.2	0.2	0.8	0.5	0.8	1.0	-0.1	0.8	0.0
Medication for pain relief, constipation, heartburn	0.3	0.5	1.9	-0.2	0.3	-0.9	0.6	0.3	1.4	1.3	0.1	0.1	0.2
Mean time to correctly identify matches	0.3	0.6	1.3	-0.9	-1.1	-0.6	-0.9	-0.3	-0.5	-0.7	-1.0	-0.2	-1.0
Chest pain or discomfort	0.3	0.5	1.1	1.1	0.7	0.7	0.5	0.5	0.3	0.3	1.0	-0.0	1.0
Whole body fat-free mass	0.3	1.5	4.0	0.8	1.4	1.4	2.0	0.7	-0.7	1.0	0.6	-1.9	0.7
Long-standing illness, disability or infirmity	0.3	0.4	2.0	-0.5	-0.4	-0.5	-0.6	-0.3	0.0	-0.2	-0.6	1.4	-0.6
Friendships satisfaction	0.3	0.4	2.6	0.2	0.1	0.2	-0.1	0.0	-0.7	-0.4	0.3	-1.6	0.2
Back pain experienced in last month	0.3	0.4	0.9	0.8	0.9	0.5	0.4	0.6	-0.3	0.3	0.8	-0.7	0.8
Whole body water mass	0.3	1.5	4.1	0.8	1.4	1.4	2.0	0.8	-0.7	1.0	0.6	-1.8	0.7
Number of self-reported non-cancer illnesses	0.3	0.5	3.7	0.1	0.2	0.5	-0.9	-0.7	-0.0	0.3	0.0	1.9	0.0
Average weekly champagne plus white wine intake	0.3	0.5	0.7	0.7	0.8	0.7	0.7	0.6	0.5	0.8	0.8	-0.4	0.8
Guilty feelings	0.3	0.4	2.7	0.3	0.2	0.7	-0.3	-0.7	0.2	0.6	0.2	1.7	0.0
Basal metabolic rate	0.3	1.5	4.2	0.8	1.3	1.3	2.0	0.9	-0.8	0.8	0.6	-1.9	0.7
Arm fat-free mass (left)	0.3	1.8	4.7	1.1	1.5	1.5	2.2	1.2	-1.0	0.8	0.9	-1.6	0.9
Age started oral contraceptive pill	0.3	0.4	1.8	0.3	0.4	0.2	0.3	-0.4	1.3	0.5	0.3	1.2	0.4
Schizophrenia vs Biploar Disorder	0.2	0.3	1.5	-0.5	0.1	-0.4	0.1	-0.0	1.2	0.9	-0.4	-0.0	-0.4
Irritable Bowel Disease (IBD)	0.2	0.6	3.2	-0.4	-0.5	-0.1	0.1	0.1	-1.0	-1.0	-0.3	1.8	-0.2
Major Depression (MDD)	0.2	0.3	1.4	0.0	0.0	0.0	0.0	-0.5	0.0	0.0	1.1	1.2	0.0
Reaction Time	0.2	0.3	1.1	-0.6	-1.1	-0.4	-0.6	-0.2	-0.3	-0.3	-0.6	0.6	-0.6
Body Mass Index (BMI) (2010)	0.2	0.3	1.1	-0.3	0.3	-0.3	0.6	0.4	0.9	1.1	-0.2	-0.3	-0.1
Mean Putamen Volume	0.2	0.3	1.0	0.3	0.3	0.7	-0.3	0.0	-1.0	-0.7	0.4	-0.7	0.3
Neuroticism (2016)	0.2	0.2	0.4	0.5	0.6	0.3	-0.6	-0.6	-0.3	0.1	0.6	0.4	0.5
Blood Eosinophil Count	0.2	1.8	5.6	-1.2	-0.8	-0.7	-1.8	-2.4	-0.7	-0.3	-1.6	-0.8	-1.6
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	0.5	-0.7	-0.4	-0.3	-0.2	0.2	-0.2	-0.2	-0.7	-0.5	-0.6
Ever had hysterectomy (womb removed)	0.2	0.3	1.0	-0.3	-0.2	-0.7	0.4	0.3	0.6	0.6	-0.2	1.0	-0.1
Medication for hormone replacement therapy	0.2	0.2	0.8	-0.3	-0.3	-0.2	-0.9	-0.5	-0.3	-0.4	-0.3	-0.2	-0.5
Supplements: Zinc	0.2	0.2	0.8	-0.3	-0.3	-0.1	-0.0	0.5	-0.4	-0.9	-0.4	-0.3	-0.4
Diabetes (father)	0.2	0.3	0.7	-0.3	-0.4	-0.4	-0.8	-0.8	0.1	-0.3	-0.4	0.8	-0.4
Leg fat-free mass (left)	0.2	1.1	3.4	0.6	1.0	1.2	1.8	0.6	-0.5	0.8	0.4	-1.7	0.5
Qualifications: CSEs or equivalent	0.2	0.3	1.5	0.3	-0.1	0.1	-0.6	-0.1	-1.2	-0.7	0.3	0.4	0.2
Chronic bronchitis/emphysema (father)	0.2	0.3	0.8	-0.5	-0.4	-0.2	0.8	0.4	0.7	0.4	-0.4	-0.9	-0.1
Impedance of leg (left)	0.2	1.1	3.3	-0.9	-1.1	-1.8	-1.0	-0.7	-0.9	-1.5	-0.6	0.5	-0.7
Leg predicted mass (left)	0.2	1.0	3.3	0.6	1.1	1.2	1.8	0.6	-0.5	0.8	0.4	-1.6	0.5
Trunk fat mass	0.2	0.8	2.9	0.6	0.8	0.7	1.4	0.9	-0.4	0.0	0.5	-1.7	0.5
Nervous feelings	0.2	0.3	0.8	-0.2	-0.1	-0.2	-0.9	-0.9	0.9	-0.0	-0.3	0.6	-0.3
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	1.2	0.2	-0.1	0.3	-0.3	-0.1	-1.1	-0.8	0.1	0.8	0.1
Weight	0.2	1.2	3.8	0.7	1.1	1.0	1.8	0.9	-0.7	0.5	0.6	-1.9	0.6
Time employed in main current job	0.2	0.2	0.7	-0.5	-0.3	-0.5	0.1	0.0	0.6	0.0	-0.5	-0.9	-0.5
Alcohol intake versus 10 years previously	0.2	0.3	0.5	0.7	0.7	0.2	-0.2	-0.2	0.5	0.7	0.7	0.6	0.6
Falls in the last year	0.2	0.3	1.1	0.4	0.3	0.4	0.5	0.2	1.1	1.0	0.3	-0.0	0.4
Number of live births	0.2	0.3	0.8	0.6	0.4	0.6	-0.3	0.3	-0.4	-0.1	0.7	0.9	0.7
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	4.2	-0.3	-0.3	-0.1	0.0	-0.1	-2.1	-1.3	-0.3	-1.3	-0.3
Illnesses of mother	0.2	0.3	2.3	-0.2	0.0	-0.3	0.3	0.2	1.5	0.4	-0.2	-0.2	-0.2
Loud music exposure frequency	0.2	0.2	1.0	-0.3	-0.1	0.1	-0.7	-0.2	-1.0	-0.2	-0.3	0.1	-0.4
Forced vital capacity (FVC), Best measure	0.2	0.8	3.1	-0.8	-0.8	-0.5	-0.0	-0.8	-1.2	-0.6	-0.8	-1.8	-0.9
Body fat percentage	0.2	0.9	1.9	0.9	0.9	0.8	1.4	1.4	0.0	0.2	0.9	-1.2	1.0
Exposure to tobacco smoke outside home	0.2	0.3	2.2	-0.1	-0.2	0.3	0.7	0.4	0.2	0.1	-0.2	-1.5	-0.2
Qualifications: College or University degree	0.2	0.7	2.4	-0.7	-0.4	0.1	-0.6	-0.7	1.6	1.0	-0.8	-0.6	-1.0
Angina (self-reported)	0.2	0.3	1.1	-0.4	-0.2	-0.3	0.3	0.1	0.8	1.1	-0.5	0.8	-0.4
Whole body fat mass	0.2	1.0	2.8	0.8	0.9	0.8	1.6	1.2	-0.4	0.2	0.6	-1.7	0.8
Alcohol intake frequency.	0.2	0.4	2.9	-0.1	-0.2	-0.6	-0.6	-0.1	-0.3	-0.1	0.1	1.7	0.1
Average weekly red wine intake	0.2	0.3	2.3	-0.1	-0.1	0.4	-0.1	0.0	-0.3	-0.2	-0.3	-1.5	-0.3
Mood swings	0.2	0.3	1.0	-0.1	-0.4	-0.4	-0.9	-0.6	-1.0	-0.7	-0.1	-0.2	-0.3
Ever had bowel cancer screening	0.2	0.2	0.7	-0.1	-0.1	0.7	-0.9	-0.4	-0.7	-0.2	-0.3	0.5	-0.3
Diabetes diagnosed by doctor	0.2	0.4	1.5	0.2	-0.1	-0.1	0.9	0.5	1.1	1.2	0.2	0.0	0.3
Commuting to job workplace: Walk	0.2	0.2	0.8	0.4	0.2	0.3	-0.1	0.6	-0.6	-0.9	0.3	-0.1	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	2.6	-0.0	0.0	0.3	0.9	1.2	-0.1	-0.2	0.0	-1.6	0.1
Average weekly beer plus cider intake	0.2	0.2	1.3	-0.2	-0.4	-0.3	0.5	-0.3	0.6	0.3	-0.3	-1.1	-0.3
Pack years of smoking	0.2	0.2	1.2	0.2	-0.2	0.2	-0.7	-0.4	-0.5	-0.4	0.2	1.1	0.0
Ulcerative Colitis (UC)	0.1	0.3	0.9	-0.5	-0.3	-0.3	0.4	0.5	-0.7	-0.9	-0.3	-0.6	-0.2
Triglycerides	0.1	0.2	0.4	-0.4	-0.2	-0.5	0.3	-0.3	0.6	0.2	-0.5	-0.4	-0.4
Blood Red Count	0.1	0.8	3.3	-0.4	-0.3	-0.7	1.0	0.6	1.8	1.6	-0.2	-0.1	-0.1
Hair Pigment	0.1	1.5	3.3	1.3	1.1	1.3	0.9	1.8	1.0	1.1	1.3	-0.6	1.3
Tanning	0.1	0.8	2.8	1.1	0.5	1.7	0.3	0.9	-0.8	-0.6	0.8	0.7	0.8
Diabetes (mother)	0.1	0.2	0.8	0.0	-0.2	0.3	-0.4	0.1	-0.6	-0.9	-0.0	0.6	0.0
Pack years adult smoking proportion	0.1	0.1	0.4	0.3	-0.1	0.2	-0.5	0.0	-0.5	-0.4	0.3	0.7	0.1
Impedance of leg (right)	0.1	0.5	1.7	-0.4	-0.7	-1.3	-0.4	-0.1	-0.8	-1.3	-0.2	-0.0	-0.2
Trunk fat percentage	0.1	0.5	1.4	0.6	0.6	0.4	1.1	0.9	-0.1	-0.1	0.4	-1.2	0.5
Bilateral oophorectomy (both ovaries removed)	0.1	0.2	1.0	-0.1	0.1	-0.1	0.6	1.0	0.0	-0.4	0.0	-0.2	0.1
Stomach or abdominal pain in last month	0.1	0.2	0.5	0.5	0.2	0.3	0.6	0.1	-0.7	0.2	0.5	-0.0	0.5
Alcohol usually taken with meals	0.1	0.1	0.7	0.0	0.1	0.4	0.4	0.1	-0.1	0.4	0.1	-0.9	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	1.9	-0.1	-0.0	0.3	0.5	0.3	-1.1	-0.8	-0.2	-1.4	-0.2
Pulse wave Arterial Stiffness index	0.1	0.1	0.3	0.3	0.1	0.4	-0.5	-0.4	-0.4	-0.2	0.1	0.1	-0.0
Hair/balding pattern: Pattern 4	0.1	0.1	0.9	0.2	0.3	0.9	-0.1	0.1	0.4	0.2	0.1	0.1	0.2
Peak expiratory flow (PEF)	0.1	0.2	1.0	0.2	0.2	0.3	0.1	0.2	-1.0	-0.6	0.1	0.4	0.0
Pulse wave peak to peak time	0.1	0.2	0.6	-0.6	-0.5	-0.8	0.2	-0.1	0.0	0.0	-0.5	-0.3	-0.4
Health satisfaction	0.1	0.1	0.6	0.1	0.1	0.2	0.5	0.3	0.8	0.5	0.1	0.4	0.1
Medication: Ibuprofen	0.1	0.1	0.3	-0.1	-0.3	-0.0	-0.4	-0.1	-0.2	-0.3	-0.1	-0.5	-0.2
Medication: Seretide 50 evohaler	0.1	0.2	0.7	-0.2	-0.1	-0.5	-0.1	0.0	-0.9	-0.7	-0.1	0.1	-0.0
Pulse rate, automated reading	0.1	0.4	1.6	0.6	0.8	0.3	0.6	1.2	-0.4	-0.4	0.6	0.2	0.7
Had major operations	0.1	0.1	0.2	-0.3	-0.1	-0.1	0.2	-0.5	0.4	0.1	-0.3	-0.4	-0.2
Leg fat-free mass (right)	0.1	0.5	1.5	0.2	0.7	0.9	1.2	0.1	-0.8	0.5	0.1	-1.2	0.1
Osteoarthritis (self-reported)	0.1	0.2	0.9	0.2	0.3	0.8	-0.1	-0.1	-0.3	-0.3	-0.0	-1.0	-0.0
Illnesses of father: None of the above (group 1)	0.1	0.2	0.5	0.5	0.3	0.3	0.0	-0.4	-0.2	-0.7	0.4	-0.4	0.3
Leg predicted mass (right)	0.1	0.5	1.7	0.2	0.7	0.8	1.2	0.0	-0.8	0.5	0.0	-1.3	0.1
Number of operations (self-reported)	0.1	0.2	1.5	0.1	0.1	-0.1	0.1	0.1	-0.6	-0.4	0.1	-1.2	0.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Medication: Ramipril	0.0	0.0	0.1	-0.2	-0.1	-0.0	0.0	0.3	0.3	0.1	-0.2	-0.1	-0.2

Hub : Genes

ICAM3

Models

Trait associations